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Results: 1 to 20 of 294


Targeting Notch, Hedgehog, and Wnt pathways in cancer stem cells: clinical update.

Takebe N, Miele L, Harris PJ, Jeong W, Bando H, Kahn M, Yang SX, Ivy SP.

Nat Rev Clin Oncol. 2015 Apr 7. doi: 10.1038/nrclinonc.2015.61. [Epub ahead of print] Review.


Severe cholestatic hepatitis due to temozolomide: an adverse drug effect to keep in mind. Case report and review of literature.

Grieco A, Tafuri MA, Biolato M, Diletto B, Di Napoli N, Balducci N, Vecchio FM, Miele L.

Medicine (Baltimore). 2015 Mar;94(12):e476. doi: 10.1097/MD.0000000000000476.


Manic Fringe Promotes a Claudin-Low Breast Cancer Phenotype through Notch-Mediated PIK3CG Induction.

Zhang S, Chung WC, Wu G, Egan SE, Miele L, Xu K.

Cancer Res. 2015 May 15;75(10):1936-43. doi: 10.1158/0008-5472.CAN-14-3303. Epub 2015 Mar 25.


AKT and 14-3-3 regulate Notch4 nuclear localization.

Ramakrishnan G, Davaakhuu G, Chung WC, Zhu H, Rana A, Filipovic A, Green AR, Atfi A, Pannuti A, Miele L, Tzivion G.

Sci Rep. 2015 Mar 5;5:8782. doi: 10.1038/srep08782.


The effect of CYP, GST, and SULT polymorphisms and their interaction with smoking on the risk of hepatocellular carcinoma.

Boccia S, Miele L, Panic N, Turati F, Arzani D, Cefalo C, Amore R, Bulajic M, Pompili M, Rapaccini G, Gasbarrini A, La Vecchia C, Grieco A.

Biomed Res Int. 2015;2015:179867. doi: 10.1155/2015/179867. Epub 2015 Jan 14.


Notch1 phenotype and clinical stage progression in non-small cell lung cancer.

Nguyen D, Rubinstein L, Takebe N, Miele L, Tomaszewski JE, Ivy P, Doroshow JH, Yang SX.

J Hematol Oncol. 2015 Feb 6;8(1):9. doi: 10.1186/s13045-014-0104-2.


Decreased Notch pathway signaling in the endometrium of women with endometriosis impairs decidualization.

Su RW, Strug MR, Joshi NR, Jeong JW, Miele L, Lessey BA, Young SL, Fazleabas AT.

J Clin Endocrinol Metab. 2015 Mar;100(3):E433-42. doi: 10.1210/jc.2014-3720. Epub 2014 Dec 29.


Role of diffusion-weighted imaging, apparent diffusion coefficient and correlation with hepatobiliary phase findings in the differentiation of hepatocellular carcinoma from dysplastic nodules in cirrhotic liver.

Inchingolo R, De Gaetano AM, Curione D, Ciresa M, Miele L, Pompili M, Vecchio FM, Giuliante F, Bonomo L.

Eur Radiol. 2015 Apr;25(4):1087-96. doi: 10.1007/s00330-014-3500-7. Epub 2014 Nov 28.


Hepatocellular carcinoma treated by conventional transarterial chemoembolization in field-practice: serum sodium predicts survival.

Biolato M, Miele L, Vero V, Racco S, Di Stasi C, Iezzi R, Zanché A, Pompili M, Rapaccini GL, La Torre G, Gasbarrini A, Grieco A.

World J Gastroenterol. 2014 Jul 7;20(25):8158-65. doi: 10.3748/wjg.v20.i25.8158.


Sunitinib significantly suppresses the proliferation, migration, apoptosis resistance, tumor angiogenesis and growth of triple-negative breast cancers but increases breast cancer stem cells.

Chinchar E, Makey KL, Gibson J, Chen F, Cole SA, Megason GC, Vijayakumar S, Miele L, Gu JW.

Vasc Cell. 2014 Jun 1;6:12. doi: 10.1186/2045-824X-6-12. eCollection 2014.


NOTCH1 Can Initiate NF-κB Activation via Cytosolic Interactions with Components of the T Cell Signalosome.

Shin HM, Tilahun ME, Cho OH, Chandiran K, Kuksin CA, Keerthivasan S, Fauq AH, Golde TE, Miele L, Thome M, Osborne BA, Minter LM.

Front Immunol. 2014 May 26;5:249. doi: 10.3389/fimmu.2014.00249. eCollection 2014.


The liver may act as a firewall mediating mutualism between the host and its gut commensal microbiota.

Balmer ML, Slack E, de Gottardi A, Lawson MA, Hapfelmeier S, Miele L, Grieco A, Van Vlierberghe H, Fahrner R, Patuto N, Bernsmeier C, Ronchi F, Wyss M, Stroka D, Dickgreber N, Heim MH, McCoy KD, Macpherson AJ.

Sci Transl Med. 2014 May 21;6(237):237ra66. doi: 10.1126/scitranslmed.3008618.


Hyper-activation of Notch3 amplifies the proliferative potential of rhabdomyosarcoma cells.

De Salvo M, Raimondi L, Vella S, Adesso L, Ciarapica R, Verginelli F, Pannuti A, Citti A, Boldrini R, Milano GM, Cacchione A, Ferrari A, Collini P, Rosolen A, Bisogno G, Alaggio R, Inserra A, Locatelli M, Stifani S, Screpanti I, Miele L, Locatelli F, Rota R.

PLoS One. 2014 May 5;9(5):e96238. doi: 10.1371/journal.pone.0096238. eCollection 2014.


Uteroglobin, a possible ligand of the lipoxin receptor inhibits serum amyloid A-driven inflammation.

Antico G, Aloman M, Lakota K, Miele L, Fiore S, Sodin-Semrl S.

Mediators Inflamm. 2014;2014:876395. doi: 10.1155/2014/876395. Epub 2014 Mar 23.


Adenosine limits the therapeutic effectiveness of anti-CTLA4 mAb in a mouse melanoma model.

Iannone R, Miele L, Maiolino P, Pinto A, Morello S.

Am J Cancer Res. 2014 Mar 1;4(2):172-81. eCollection 2014.


Intestinal permeability is increased in children with non-alcoholic fatty liver disease, and correlates with liver disease severity.

Giorgio V, Miele L, Principessa L, Ferretti F, Villa MP, Negro V, Grieco A, Alisi A, Nobili V.

Dig Liver Dis. 2014 Jun;46(6):556-60. doi: 10.1016/j.dld.2014.02.010. Epub 2014 Mar 12.


Non-Canonical Notch Signaling Drives Activation and Differentiation of Peripheral CD4(+) T Cells.

Dongre A, Surampudi L, Lawlor RG, Fauq AH, Miele L, Golde TE, Minter LM, Osborne BA.

Front Immunol. 2014 Feb 12;5:54. doi: 10.3389/fimmu.2014.00054. eCollection 2014.


Abstract 121: Evaluation of Otology Outcomes After Surgical Treatment of Symptomatic Pierre Robin Sequence: A Cohort Comparison Study Between Furlow Palatoplasty vs. Radical Intravelar Veloplasty.

Miele LF, Dedhia K, Chi D, Mehta D, Kumar AR.

Plast Reconstr Surg. 2014 Mar;133(3 Suppl):136-7. doi: 10.1097/01.prs.0000444947.31475.b9. No abstract available.


Targeting Met and Notch in the Lfng-deficient, Met-amplified triple-negative breast cancer.

Zhang S, Chung WC, Miele L, Xu K.

Cancer Biol Ther. 2014 May;15(5):633-42. doi: 10.4161/cbt.28180. Epub 2014 Feb 20.

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