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Diagnostic Dilemma in the Treatment of a Fatal Case of Bloody Diarrhea.

Mahapatra S, Michie SA, Sylvester K, Cornfield D.

J Investig Med High Impact Case Rep. 2016 Mar 17;4(1):2324709616638698. doi: 10.1177/2324709616638698. eCollection 2016 Jan-Mar.


Humanized thymidine kinase-NOG mice can be used to identify drugs that cause animal-specific hepatotoxicity: a case study with furosemide.

Xu D, Michie SA, Zheng M, Takeda S, Wu M, Peltz G.

J Pharmacol Exp Ther. 2015 Jul;354(1):73-8. doi: 10.1124/jpet.115.224493. Epub 2015 May 11.


A silk-based encapsulation platform for pancreatic islet transplantation improves islet function in vivo.

Hamilton DC, Shih HH, Schubert RA, Michie SA, Staats PN, Kaplan DL, Fontaine MJ.

J Tissue Eng Regen Med. 2015 Jan 26. doi: 10.1002/term.1990. [Epub ahead of print]


Chimeric TK-NOG mice: a predictive model for cholestatic human liver toxicity.

Xu D, Wu M, Nishimura S, Nishimura T, Michie SA, Zheng M, Yang Z, Yates AJ, Day JS, Hillgren KM, Takeda ST, Guan Y, Guo Y, Peltz G.

J Pharmacol Exp Ther. 2015 Feb;352(2):274-80. doi: 10.1124/jpet.114.220798. Epub 2014 Nov 25.


VCAM-1/α4β1 integrin interaction is crucial for prompt recruitment of immune T cells into the brain during the early stage of reactivation of chronic infection with Toxoplasma gondii to prevent toxoplasmic encephalitis.

Sa Q, Ochiai E, Sengoku T, Wilson ME, Brogli M, Crutcher S, Michie SA, Xu B, Payne L, Wang X, Suzuki Y.

Infect Immun. 2014 Jul;82(7):2826-39. doi: 10.1128/IAI.01494-13. Epub 2014 Apr 21.


Fialuridine induces acute liver failure in chimeric TK-NOG mice: a model for detecting hepatic drug toxicity prior to human testing.

Xu D, Nishimura T, Nishimura S, Zhang H, Zheng M, Guo YY, Masek M, Michie SA, Glenn J, Peltz G.

PLoS Med. 2014 Apr 15;11(4):e1001628. doi: 10.1371/journal.pmed.1001628. eCollection 2014 Apr.


CCR7 directs the recruitment of T cells into inflamed pancreatic islets of nonobese diabetic (NOD) mice.

Shan Z, Xu B, Mikulowska-Mennis A, Michie SA.

Immunol Res. 2014 May;58(2-3):351-7. doi: 10.1007/s12026-014-8500-9.


Systems analysis of primary Sjögren's syndrome pathogenesis in salivary glands identifies shared pathways in human and a mouse model.

Horvath S, Nazmul-Hossain AN, Pollard RP, Kroese FG, Vissink A, Kallenberg CG, Spijkervet FK, Bootsma H, Michie SA, Gorr SU, Peck AB, Cai C, Zhou H, Wong DT.

Arthritis Res Ther. 2012 Nov 1;14(6):R238. doi: 10.1186/ar4081.


Protein polymer hydrogels: effects of endotoxin on biocompatibility.

Beenken-Rothkopf LN, Karfeld-Sulzer LS, Zhang X, Kissler H, Michie SA, Kaufman DB, Fontaine MJ, Barron AE.

J Biomater Appl. 2013 Sep;28(3):395-406. doi: 10.1177/0885328212454555. Epub 2012 Jul 24.


Text-mining applied to autoimmune disease research: the Sjögren's syndrome knowledge base.

Gorr SU, Wennblom TJ, Horvath S, Wong DT, Michie SA.

BMC Musculoskelet Disord. 2012 Jul 3;13:119. doi: 10.1186/1471-2474-13-119.


Alpha4beta7 integrin/MAdCAM-1 adhesion pathway is crucial for B cell migration into pancreatic lymph nodes in nonobese diabetic mice.

Xu B, Cook RE, Michie SA.

J Autoimmun. 2010 Sep;35(2):124-9. doi: 10.1016/j.jaut.2010.04.002. Epub 2010 May 21.


Removal of Toxoplasma gondii cysts from the brain by perforin-mediated activity of CD8+ T cells.

Suzuki Y, Wang X, Jortner BS, Payne L, Ni Y, Michie SA, Xu B, Kudo T, Perkins S.

Am J Pathol. 2010 Apr;176(4):1607-13. doi: 10.2353/ajpath.2010.090825. Epub 2010 Feb 18.


Expression of endothelia and lymphocyte adhesion molecules in bronchus-associated lymphoid tissue (BALT) in adult human lung.

Kawamata N, Xu B, Nishijima H, Aoyama K, Kusumoto M, Takeuchi T, Tei C, Michie SA, Matsuyama T.

Respir Res. 2009 Oct 22;10:97. doi: 10.1186/1465-9921-10-97.


PPAR-delta senses and orchestrates clearance of apoptotic cells to promote tolerance.

Mukundan L, Odegaard JI, Morel CR, Heredia JE, Mwangi JW, Ricardo-Gonzalez RR, Goh YP, Eagle AR, Dunn SE, Awakuni JU, Nguyen KD, Steinman L, Michie SA, Chawla A.

Nat Med. 2009 Nov;15(11):1266-72. doi: 10.1038/nm.2048. Epub 2009 Oct 18.


Targeting tumor-associated macrophages in an experimental glioma model with a recombinant immunotoxin to folate receptor beta.

Nagai T, Tanaka M, Tsuneyoshi Y, Xu B, Michie SA, Hasui K, Hirano H, Arita K, Matsuyama T.

Cancer Immunol Immunother. 2009 Oct;58(10):1577-86. doi: 10.1007/s00262-009-0667-x. Epub 2009 Feb 24.


Systems biology analysis of Sjögren's syndrome and mucosa-associated lymphoid tissue lymphoma in parotid glands.

Hu S, Zhou M, Jiang J, Wang J, Elashoff D, Gorr S, Michie SA, Spijkervet FK, Bootsma H, Kallenberg CG, Vissink A, Horvath S, Wong DT.

Arthritis Rheum. 2009 Jan;60(1):81-92. doi: 10.1002/art.24150.


TSG-6 protein expression in the pancreatic islets of NOD mice.

Kvezereli M, Michie SA, Yu T, Creusot RJ, Fontaine MJ.

J Mol Histol. 2008 Dec;39(6):585-93. doi: 10.1007/s10735-008-9199-5. Epub 2008 Nov 1.


Interferon-alpha initiates type 1 diabetes in nonobese diabetic mice.

Li Q, Xu B, Michie SA, Rubins KH, Schreriber RD, McDevitt HO.

Proc Natl Acad Sci U S A. 2008 Aug 26;105(34):12439-44. doi: 10.1073/pnas.0806439105. Epub 2008 Aug 20.


Keratin overexpression levels correlate with the extent of spontaneous pancreatic injury.

Toivola DM, Nakamichi I, Strnad P, Michie SA, Ghori N, Harada M, Zeh K, Oshima RG, Baribault H, Omary MB.

Am J Pathol. 2008 Apr;172(4):882-92. doi: 10.2353/ajpath.2008.070830. Epub 2008 Mar 18.


Lack of lymphoid chemokines CCL19 and CCL21 enhances allergic airway inflammation in mice.

Xu B, Aoyama K, Kusumoto M, Matsuzawa A, Butcher EC, Michie SA, Matsuyama T, Takeuchi T.

Int Immunol. 2007 Jun;19(6):775-84. Epub 2007 May 19.

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