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Results: 1 to 20 of 42

1.

Airway Basal stem/progenitor cells have diminished capacity to regenerate airway epithelium in chronic obstructive pulmonary disease.

Staudt MR, Buro-Auriemma LJ, Walters MS, Salit J, Vincent T, Shaykhiev R, Mezey JG, Tilley AE, Kaner RJ, Ho MW, Crystal RG.

Am J Respir Crit Care Med. 2014 Oct 15;190(8):955-8. doi: 10.1164/rccm.201406-1167LE. No abstract available.

PMID:
25317467
[PubMed - in process]
2.

Smoking accelerates aging of the small airway epithelium.

Walters MS, De BP, Salit J, Buro-Auriemma LJ, Wilson T, Rogalski AM, Lief L, Hackett NR, Staudt MR, Tilley AE, Harvey BG, Kaner RJ, Mezey JG, Ashbridge B, Moore MA, Crystal RG.

Respir Res. 2014 Sep 24;15(1):94. [Epub ahead of print]

PMID:
25248511
[PubMed - as supplied by publisher]
Free PMC Article
3.

lrgpr: interactive linear mixed model analysis of genome-wide association studies with composite hypothesis testing and regression diagnostics in R.

Hoffman GE, Mezey JG, Schadt EE.

Bioinformatics. 2014 Nov 1;30(21):3134-5. doi: 10.1093/bioinformatics/btu435. Epub 2014 Jul 16.

PMID:
25035399
[PubMed - in process]
4.

Smoking dysregulates the human airway basal cell transcriptome at COPD risk locus 19q13.2.

Ryan DM, Vincent TL, Salit J, Walters MS, Agosto-Perez F, Shaykhiev R, Strulovici-Barel Y, Downey RJ, Buro-Auriemma LJ, Staudt MR, Hackett NR, Mezey JG, Crystal RG.

PLoS One. 2014 Feb 3;9(2):e88051. doi: 10.1371/journal.pone.0088051. eCollection 2014.

PMID:
24498427
[PubMed - indexed for MEDLINE]
Free PMC Article
5.

HEFT: eQTL analysis of many thousands of expressed genes while simultaneously controlling for hidden factors.

Gao C, Tignor NL, Salit J, Strulovici-Barel Y, Hackett NR, Crystal RG, Mezey JG.

Bioinformatics. 2014 Feb 1;30(3):369-76. doi: 10.1093/bioinformatics/btt690. Epub 2013 Dec 4.

PMID:
24307700
[PubMed - indexed for MEDLINE]
6.

Prevalence of the apolipoprotein E Arg145Cys dyslipidemia at-risk polymorphism in African-derived populations.

Abou Ziki MD, Strulovici-Barel Y, Hackett NR, Rodriguez-Flores JL, Mezey JG, Salit J, Radisch S, Hollmann C, Chouchane L, Malek J, Zirie MA, Jayyuosi A, Gotto AM Jr, Crystal RG.

Am J Cardiol. 2014 Jan 15;113(2):302-8. doi: 10.1016/j.amjcard.2013.09.021. Epub 2013 Oct 3.

PMID:
24239320
[PubMed - indexed for MEDLINE]
7.

Exome sequencing identifies potential risk variants for Mendelian disorders at high prevalence in Qatar.

Rodriguez-Flores JL, Fakhro K, Hackett NR, Salit J, Fuller J, Agosto-Perez F, Gharbiah M, Malek JA, Zirie M, Jayyousi A, Badii R, Al-Nabet Al-Marri A, Chouchane L, Stadler DJ, Mezey JG, Crystal RG.

Hum Mutat. 2014 Jan;35(1):105-16. doi: 10.1002/humu.22460. Epub 2013 Nov 10.

PMID:
24123366
[PubMed - indexed for MEDLINE]
8.

IQCB1 and PDE6B mutations cause similar early onset retinal degenerations in two closely related terrier dog breeds.

Goldstein O, Mezey JG, Schweitzer PA, Boyko AR, Gao C, Bustamante CD, Jordan JA, Aguirre GD, Acland GM.

Invest Ophthalmol Vis Sci. 2013 Oct 25;54(10):7005-19. doi: 10.1167/iovs.13-12915.

PMID:
24045995
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

High correlation of the response of upper and lower lobe small airway epithelium to smoking.

Harvey BG, Strulovici-Barel Y, Vincent TL, Mezey JG, Raviram R, Gordon C, Salit J, Tilley AE, Chung A, Sanders A, Crystal RG.

PLoS One. 2013 Sep 9;8(9):e72669. doi: 10.1371/journal.pone.0072669. eCollection 2013.

PMID:
24039793
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Spectrum of ocular manifestations in CLN2-associated batten (Jansky-Bielschowsky) disease correlate with advancing age and deteriorating neurological function.

Orlin A, Sondhi D, Witmer MT, Wessel MM, Mezey JG, Kaminsky SM, Hackett NR, Yohay K, Kosofsky B, Souweidane MM, Kaplitt MG, D'Amico DJ, Crystal RG, Kiss S.

PLoS One. 2013 Aug 28;8(8):e73128. doi: 10.1371/journal.pone.0073128. eCollection 2013.

PMID:
24015292
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Differential expression of vitamin E and selenium-responsive genes by disease severity in chronic obstructive pulmonary disease.

Agler AH, Crystal RG, Mezey JG, Fuller J, Gao C, Hansen JG, Cassano PA.

COPD. 2013 Aug;10(4):450-8. doi: 10.3109/15412555.2012.761958.

PMID:
23875740
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

PUMA: a unified framework for penalized multiple regression analysis of GWAS data.

Hoffman GE, Logsdon BA, Mezey JG.

PLoS Comput Biol. 2013;9(6):e1003101. doi: 10.1371/journal.pcbi.1003101. Epub 2013 Jun 27.

PMID:
23825936
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Safety of direct cardiac administration of AdVEGF-All6A+, a replication-deficient adenovirus vector cDNA/genomic hybrid expressing all three major isoforms of human vascular endothelial growth factor, to the ischemic myocardium of rats.

Kaminsky SM, Quach L, Chen S, Pierre-Destine L, Van de Graaf B, Monette S, Rosenberg JB, De BP, Sondhi D, Hackett NR, Mezey JG, Rosengart TK, Crystal RG.

Hum Gene Ther Clin Dev. 2013 Mar;24(1):38-46. doi: 10.1089/humc.2013.054.

PMID:
23692382
[PubMed - indexed for MEDLINE]
14.

Lung adenocarcinoma subtypes based on expression of human airway basal cell genes.

Fukui T, Shaykhiev R, Agosto-Perez F, Mezey JG, Downey RJ, Travis WD, Crystal RG.

Eur Respir J. 2013 Nov;42(5):1332-44. doi: 10.1183/09031936.00144012. Epub 2013 May 3.

PMID:
23645403
[PubMed - indexed for MEDLINE]
15.

PCAdmix: principal components-based assignment of ancestry along each chromosome in individuals with admixed ancestry from two or more populations.

Brisbin A, Bryc K, Byrnes J, Zakharia F, Omberg L, Degenhardt J, Reynolds A, Ostrer H, Mezey JG, Bustamante CD.

Hum Biol. 2012 Aug;84(4):343-64. doi: 10.3378/027.084.0401.

PMID:
23249312
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Exome sequencing of only seven Qataris identifies potentially deleterious variants in the Qatari population.

Rodriguez-Flores JL, Fuller J, Hackett NR, Salit J, Malek JA, Al-Dous E, Chouchane L, Zirie M, Jayoussi A, Mahmoud MA, Crystal RG, Mezey JG.

PLoS One. 2012;7(11):e47614. doi: 10.1371/journal.pone.0047614. Epub 2012 Nov 6.

PMID:
23139751
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Airway epithelial expression of TLR5 is downregulated in healthy smokers and smokers with chronic obstructive pulmonary disease.

Wang R, Ahmed J, Wang G, Hassan I, Strulovici-Barel Y, Salit J, Mezey JG, Crystal RG.

J Immunol. 2012 Sep 1;189(5):2217-25. doi: 10.4049/jimmunol.1101895. Epub 2012 Aug 1.

PMID:
22855713
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Four loci explain 83% of size variation in the horse.

Makvandi-Nejad S, Hoffman GE, Allen JJ, Chu E, Gu E, Chandler AM, Loredo AI, Bellone RR, Mezey JG, Brooks SA, Sutter NB.

PLoS One. 2012;7(7):e39929. doi: 10.1371/journal.pone.0039929. Epub 2012 Jul 11.

PMID:
22808074
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inferring genome-wide patterns of admixture in Qataris using fifty-five ancestral populations.

Omberg L, Salit J, Hackett N, Fuller J, Matthew R, Chouchane L, Rodriguez-Flores JL, Bustamante C, Crystal RG, Mezey JG.

BMC Genet. 2012 Jun 26;13:49. doi: 10.1186/1471-2156-13-49.

PMID:
22734698
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Empirical Bayes conditional independence graphs for regulatory network recovery.

Mahdi R, Madduri AS, Wang G, Strulovici-Barel Y, Salit J, Hackett NR, Crystal RG, Mezey JG.

Bioinformatics. 2012 Aug 1;28(15):2029-36. doi: 10.1093/bioinformatics/bts312. Epub 2012 Jun 8.

PMID:
22685074
[PubMed - indexed for MEDLINE]
Free PMC Article

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