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Items: 1 to 20 of 75

1.

Long-Term Persistence of Bi-functionality Contributes to the Robustness of Microbial Life through Exaptation.

Plach MG, Reisinger B, Sterner R, Merkl R.

PLoS Genet. 2016 Jan 29;12(1):e1005836. doi: 10.1371/journal.pgen.1005836. eCollection 2016 Jan.

2.

An assessment of catalytic residue 3D ensembles for the prediction of enzyme function.

Žváček C, Friedrichs G, Heizinger L, Merkl R.

BMC Bioinformatics. 2015 Nov 4;16:359. doi: 10.1186/s12859-015-0807-6.

3.

Conversion of anthranilate synthase into isochorismate synthase: implications for the evolution of chorismate-utilizing enzymes.

Plach MG, Löffler P, Merkl R, Sterner R.

Angew Chem Int Ed Engl. 2015 Sep 14;54(38):11270-4. doi: 10.1002/anie.201505063.

PMID:
26352034
4.

Ancestral protein reconstruction: techniques and applications.

Merkl R, Sterner R.

Biol Chem. 2016 Jan 1;397(1):1-21. doi: 10.1515/hsz-2015-0158.

PMID:
26351909
5.

The extended AT-hook is a novel RNA binding motif.

Filarsky M, Zillner K, Araya I, Villar-Garea A, Merkl R, Längst G, Németh A.

RNA Biol. 2015;12(8):864-76. doi: 10.1080/15476286.2015.1060394.

6.

Maize EMBRYO SAC family peptides interact differentially with pollen tubes and fungal cells.

Woriedh M, Merkl R, Dresselhaus T.

J Exp Bot. 2015 Aug;66(17):5205-16. doi: 10.1093/jxb/erv268. Epub 2015 Jun 12.

7.

Improving thermal and detergent stability of Bacillus stearothermophilus neopullulanase by rational enzyme design.

Ece S, Evran S, Janda JO, Merkl R, Sterner R.

Protein Eng Des Sel. 2015 Jun;28(6):147-51. doi: 10.1093/protein/gzv001. Epub 2015 Feb 12.

PMID:
25680359
8.

TNFα signalling primes chromatin for NF-κB binding and induces rapid and widespread nucleosome repositioning.

Diermeier S, Kolovos P, Heizinger L, Schwartz U, Georgomanolis T, Zirkel A, Wedemann G, Grosveld F, Knoch TA, Merkl R, Cook PR, Längst G, Papantonis A.

Genome Biol. 2014 Dec 3;15(12):536. doi: 10.1186/s13059-014-0536-6.

9.

TrpB2 enzymes are O-phospho-l-serine dependent tryptophan synthases.

Busch F, Rajendran C, Mayans O, Löffler P, Merkl R, Sterner R.

Biochemistry. 2014 Sep 30;53(38):6078-83. doi: 10.1021/bi500977y. Epub 2014 Sep 17.

PMID:
25184516
10.

Generation of catalytic human Ago4 identifies structural elements important for RNA cleavage.

Hauptmann J, Kater L, Löffler P, Merkl R, Meister G.

RNA. 2014 Oct;20(10):1532-8. doi: 10.1261/rna.045203.114. Epub 2014 Aug 11.

11.

[Skin changes in the face. " I have such odd acne around the nose". Perioral dermatitis].

Müller A, Merkl RK, Möbius D.

MMW Fortschr Med. 2014 May 28;156(10):7, 47. German. No abstract available.

PMID:
24930211
12.

Oleic acid is a precursor of linoleic acid and the male sex pheromone in Nasonia vitripennis.

Blaul B, Steinbauer R, Merkl P, Merkl R, Tschochner H, Ruther J.

Insect Biochem Mol Biol. 2014 Aug;51:33-40. doi: 10.1016/j.ibmb.2014.05.007. Epub 2014 May 27.

PMID:
24874439
13.

H2rs: deducing evolutionary and functionally important residue positions by means of an entropy and similarity based analysis of multiple sequence alignments.

Janda JO, Popal A, Bauer J, Busch M, Klocke M, Spitzer W, Keller J, Merkl R.

BMC Bioinformatics. 2014 Apr 27;15:118. doi: 10.1186/1471-2105-15-118.

14.

The NHL domain of BRAT is an RNA-binding domain that directly contacts the hunchback mRNA for regulation.

Loedige I, Stotz M, Qamar S, Kramer K, Hennig J, Schubert T, Löffler P, Längst G, Merkl R, Urlaub H, Meister G.

Genes Dev. 2014 Apr 1;28(7):749-64. doi: 10.1101/gad.236513.113.

15.

Exploiting protein symmetry to design light-controllable enzyme inhibitors.

Reisinger B, Kuzmanovic N, Löffler P, Merkl R, König B, Sterner R.

Angew Chem Int Ed Engl. 2014 Jan 7;53(2):595-8. doi: 10.1002/anie.201307207. Epub 2013 Nov 25.

PMID:
24520030
16.

Evidence for the existence of elaborate enzyme complexes in the Paleoarchean era.

Reisinger B, Sperl J, Holinski A, Schmid V, Rajendran C, Carstensen L, Schlee S, Blanquart S, Merkl R, Sterner R.

J Am Chem Soc. 2014 Jan 8;136(1):122-9. doi: 10.1021/ja4115677. Epub 2013 Dec 23.

PMID:
24364418
17.

CLIPS-4D: a classifier that distinguishes structurally and functionally important residue-positions based on sequence and 3D data.

Janda JO, Meier A, Merkl R.

Bioinformatics. 2013 Dec 1;29(23):3029-35. doi: 10.1093/bioinformatics/btt519. Epub 2013 Sep 18.

18.

Antioxidant effect of mono- and dihydroxyphenols in sunflower oil with different levels of naturally present tocopherols.

Hrádková I, Merkl R, Smidrkal J, Kyselka J, Filip V.

Eur J Lipid Sci Technol. 2013 Jul;115(7):747-755. Epub 2013 May 17.

19.

[The nodule hurts more and more... Deep venous thrombosis].

Müller A, Möbius D, Merkl RK.

MMW Fortschr Med. 2013 Jul 25;155(13):5. German. No abstract available.

PMID:
23964484
20.

[Objective and subjective findings. There are considerable differences].

Möbius D, Müller A, Merkl RK.

MMW Fortschr Med. 2013 Apr 4;155(6):5. German. No abstract available.

PMID:
23729047
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