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Results: 20

1.

In vivo safety, biodistribution and antitumor effects of uPAR retargeted oncolytic measles virus in syngeneic cancer models.

Jing Y, Zaias J, Duncan R, Russell SJ, Merchan JR.

Gene Ther. 2014 Mar;21(3):289-97. doi: 10.1038/gt.2013.84. Epub 2014 Jan 16.

PMID:
24430235
[PubMed - in process]
Free PMC Article
2.

Successful use of Trastuzumab with anthracycline-based chemotherapy followed by trastuzumab maintenance in patients with advanced HER2-positive gastric cancer.

Palacio S, Loaiza-Bonilla A, Kittaneh M, Kyriakopoulos C, Ochoa RE, Escobar M, Arango B, Restrepo MH, Merchan JR, Rocha Lima CM, Hosein PJ.

Anticancer Res. 2014 Jan;34(1):301-6.

PMID:
24403478
[PubMed - indexed for MEDLINE]
3.

Preclinical safety and activity of recombinant VSV-IFN-β in an immunocompetent model of squamous cell carcinoma of the head and neck.

Kurisetty VV, Heiber J, Myers R, Pereira GS, Goodwin JW, Federspiel MJ, Russell SJ, Peng KW, Barber G, Merchan JR.

Head Neck. 2013 Sep 30. doi: 10.1002/hed.23502. [Epub ahead of print]

PMID:
24115092
[PubMed - as supplied by publisher]
4.

Pazopanib versus sunitinib in metastatic renal-cell carcinoma.

Motzer RJ, Hutson TE, Cella D, Reeves J, Hawkins R, Guo J, Nathan P, Staehler M, de Souza P, Merchan JR, Boleti E, Fife K, Jin J, Jones R, Uemura H, De Giorgi U, Harmenberg U, Wang J, Sternberg CN, Deen K, McCann L, Hackshaw MD, Crescenzo R, Pandite LN, Choueiri TK.

N Engl J Med. 2013 Aug 22;369(8):722-31. doi: 10.1056/NEJMoa1303989.

PMID:
23964934
[PubMed - indexed for MEDLINE]
Free Article
5.

Endoplasmic reticulum stress induced by 2-deoxyglucose but not glucose starvation activates AMPK through CaMKKβ leading to autophagy.

Xi H, Barredo JC, Merchan JR, Lampidis TJ.

Biochem Pharmacol. 2013 May 15;85(10):1463-77. doi: 10.1016/j.bcp.2013.02.037. Epub 2013 Mar 13.

PMID:
23500541
[PubMed - indexed for MEDLINE]
6.

Role of plasminogen activator inhibitor-1 in urokinase's paradoxical in vivo tumor suppressing or promoting effects.

Jing Y, Kovacs K, Kurisetty V, Jiang Z, Tsinoremas N, Merchan JR.

Mol Cancer Res. 2012 Oct;10(10):1271-81. doi: 10.1158/1541-7786.MCR-12-0145. Epub 2012 Aug 21.

PMID:
22912336
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

A retrospective study of neoadjuvant FOLFIRINOX in unresectable or borderline-resectable locally advanced pancreatic adenocarcinoma.

Hosein PJ, Macintyre J, Kawamura C, Maldonado JC, Ernani V, Loaiza-Bonilla A, Narayanan G, Ribeiro A, Portelance L, Merchan JR, Levi JU, Rocha-Lima CM.

BMC Cancer. 2012 May 29;12:199. doi: 10.1186/1471-2407-12-199.

PMID:
22642850
[PubMed - indexed for MEDLINE]
Free PMC Article
8.

A phase II trial of nab-Paclitaxel as second-line therapy in patients with advanced pancreatic cancer.

Hosein PJ, de Lima Lopes G Jr, Pastorini VH, Gomez C, Macintyre J, Zayas G, Reis I, Montero AJ, Merchan JR, Rocha Lima CM.

Am J Clin Oncol. 2013 Apr;36(2):151-6. doi: 10.1097/COC.0b013e3182436e8c.

PMID:
22307213
[PubMed - indexed for MEDLINE]
9.

The anticancer effects of chaetocin are independent of programmed cell death and hypoxia, and are associated with inhibition of endothelial cell proliferation.

Isham CR, Tibodeau JD, Bossou AR, Merchan JR, Bible KC.

Br J Cancer. 2012 Jan 17;106(2):314-23. doi: 10.1038/bjc.2011.522. Epub 2011 Dec 20.

PMID:
22187030
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Combined histone deacetylase and cyclooxygenase inhibition achieves enhanced antiangiogenic effects in lung cancer cells.

Wang X, Li G, Wang A, Zhang Z, Merchan JR, Halmos B.

Mol Carcinog. 2013 Mar;52(3):218-28. doi: 10.1002/mc.21846. Epub 2011 Nov 28.

PMID:
22121107
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Phase II study of gemcitabine, oxaliplatin, and cetuximab in advanced pancreatic cancer.

Merchan JR, Ferrell A, Macintyre J, Ciombor KK, Levi J, Ribeiro A, Sleeman D, Flores A, Lopes G, Rocha-Lima CM.

Am J Clin Oncol. 2012 Oct;35(5):446-50.

PMID:
21552097
[PubMed - indexed for MEDLINE]
12.

Antiangiogenic activity of 2-deoxy-D-glucose.

Merchan JR, Kovács K, Railsback JW, Kurtoglu M, Jing Y, Piña Y, Gao N, Murray TG, Lehrman MA, Lampidis TJ.

PLoS One. 2010 Oct 27;5(10):e13699. doi: 10.1371/journal.pone.0013699.

PMID:
21060881
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Tumor and vascular targeting of a novel oncolytic measles virus retargeted against the urokinase receptor.

Jing Y, Tong C, Zhang J, Nakamura T, Iankov I, Russell SJ, Merchan JR.

Cancer Res. 2009 Feb 15;69(4):1459-68. doi: 10.1158/0008-5472.CAN-08-2628. Epub 2009 Feb 10.

PMID:
19208845
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Sunitinib in patients with metastatic renal cell carcinoma.

Motzer RJ, Rini BI, Bukowski RM, Curti BD, George DJ, Hudes GR, Redman BG, Margolin KA, Merchan JR, Wilding G, Ginsberg MS, Bacik J, Kim ST, Baum CM, Michaelson MD.

JAMA. 2006 Jun 7;295(21):2516-24.

PMID:
16757724
[PubMed - indexed for MEDLINE]
15.

Protease activity of urokinase and tumor progression in a syngeneic mammary cancer model.

Merchan JR, Tang J, Hu G, Lin Y, Mutter W, Tong C, Karumanchi SA, Russell SJ, Sukhatme VP.

J Natl Cancer Inst. 2006 Jun 7;98(11):756-64.

PMID:
16757700
[PubMed - indexed for MEDLINE]
Free Article
16.

A scoring algorithm to predict survival for patients with metastatic clear cell renal cell carcinoma: a stratification tool for prospective clinical trials.

Leibovich BC, Cheville JC, Lohse CM, Zincke H, Frank I, Kwon ED, Merchan JR, Blute ML.

J Urol. 2005 Nov;174(5):1759-63; discussion 1763.

PMID:
16217278
[PubMed - indexed for MEDLINE]
17.

Targeted measles virus vector displaying echistatin infects endothelial cells via alpha(v)beta3 and leads to tumor regression.

Hallak LK, Merchan JR, Storgard CM, Loftus JC, Russell SJ.

Cancer Res. 2005 Jun 15;65(12):5292-300.

PMID:
15958576
[PubMed - indexed for MEDLINE]
Free Article
18.

Increased endothelial uptake of paclitaxel as a potential mechanism for its antiangiogenic effects: potentiation by Cox-2 inhibition.

Merchan JR, Jayaram DR, Supko JG, He X, Bubley GJ, Sukhatme VP.

Int J Cancer. 2005 Jan 20;113(3):490-8.

PMID:
15455390
[PubMed - indexed for MEDLINE]
19.

Antiangiogenic property of human thrombin.

Chan B, Merchan JR, Kale S, Sukhatme VP.

Microvasc Res. 2003 Jul;66(1):1-14. Review.

PMID:
12826069
[PubMed - indexed for MEDLINE]
20.

In vitro and in vivo induction of antiangiogenic activity by plasminogen activators and captopril.

Merchan JR, Chan B, Kale S, Schnipper LE, Sukhatme VP.

J Natl Cancer Inst. 2003 Mar 5;95(5):388-99.

PMID:
12618504
[PubMed - indexed for MEDLINE]
Free Article

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