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Results: 1 to 20 of 214


Drug resistance. K13-propeller mutations confer artemisinin resistance in Plasmodium falciparum clinical isolates.

Straimer J, Gnädig NF, Witkowski B, Amaratunga C, Duru V, Ramadani AP, Dacheux M, Khim N, Zhang L, Lam S, Gregory PD, Urnov FD, Mercereau-Puijalon O, Benoit-Vical F, Fairhurst RM, Ménard D, Fidock DA.

Science. 2015 Jan 23;347(6220):428-31. doi: 10.1126/science.1260867. Epub 2014 Dec 11.


Red cells from ferrochelatase-deficient erythropoietic protoporphyria patients are resistant to growth of malarial parasites.

Smith CM, Jerkovic A, Puy H, Winship I, Deybach JC, Gouya L, van Dooren G, Goodman CD, Sturm A, Manceau H, McFadden GI, David P, Mercereau-Puijalon O, Burgio G, McMorran BJ, Foote SJ.

Blood. 2015 Jan 15;125(3):534-41. doi: 10.1182/blood-2014-04-567149. Epub 2014 Nov 20.


Comparative analysis of IgG responses to Plasmodium falciparum MSP1p19 and PF13-DBL1α1 using ELISA and a magnetic bead-based duplex assay (MAGPIX®-Luminex) in a Senegalese meso-endemic community.

Perraut R, Richard V, Varela ML, Trape JF, Guillotte M, Tall A, Toure A, Sokhna C, Vigan-Womas I, Mercereau-Puijalon O.

Malar J. 2014 Oct 17;13:410. doi: 10.1186/1475-2875-13-410.


Effects of mefloquine use on Plasmodium vivax multidrug resistance.

Khim N, Andrianaranjaka V, Popovici J, Kim S, Ratsimbasoa A, Benedet C, Barnadas C, Durand R, Thellier M, Legrand E, Musset L, Menegon M, Severini C, Nour BY, Tichit M, Bouchier C, Mercereau-Puijalon O, Ménard D.

Emerg Infect Dis. 2014 Oct;20(10):1637-44. doi: 10.3201/eid2010.140411.


A novel Plasmodium-specific prodomain fold regulates the malaria drug target SUB1 subtilase.

Giganti D, Bouillon A, Tawk L, Robert F, Martinez M, Crublet E, Weber P, Girard-Blanc C, Petres S, Haouz A, Hernandez JF, Mercereau-Puijalon O, Alzari PM, Barale JC.

Nat Commun. 2014 Sep 10;5:4833. doi: 10.1038/ncomms5833.


Independent emergence of artemisinin resistance mutations among Plasmodium falciparum in Southeast Asia.

Takala-Harrison S, Jacob CG, Arze C, Cummings MP, Silva JC, Dondorp AM, Fukuda MM, Hien TT, Mayxay M, Noedl H, Nosten F, Kyaw MP, Nhien NT, Imwong M, Bethell D, Se Y, Lon C, Tyner SD, Saunders DL, Ariey F, Mercereau-Puijalon O, Menard D, Newton PN, Khanthavong M, Hongvanthong B, Starzengruber P, Fuehrer HP, Swoboda P, Khan WA, Phyo AP, Nyunt MM, Nyunt MH, Brown TS, Adams M, Pepin CS, Bailey J, Tan JC, Ferdig MT, Clark TG, Miotto O, MacInnis B, Kwiatkowski DP, White NJ, Ringwald P, Plowe CV.

J Infect Dis. 2015 Mar 1;211(5):670-9. doi: 10.1093/infdis/jiu491. Epub 2014 Sep 1.


[Towards a better understanding of the molecular mechanisms of P. falciparum resistance to artemisinin].

Khim N, Witkowski B, Duru V, Ariey F, Mercereau-Puijalon O, Ménard D.

Med Sci (Paris). 2014 Aug-Sep;30(8-9):727-9. doi: 10.1051/medsci/20143008004. Epub 2014 Sep 1. French. No abstract available.


Molecular surveillance for artemisinin resistance in Africa.

Roper C, Alifrangis M, Ariey F, Talisuna A, Menard D, Mercereau-Puijalon O, Ringwald P.

Lancet Infect Dis. 2014 Aug;14(8):668-70. doi: 10.1016/S1473-3099(14)70826-6. No abstract available.


Association of antibody responses to the conserved Plasmodium falciparum merozoite surface protein 5 with protection against clinical malaria.

Perraut R, Joos C, Sokhna C, Polson HE, Trape JF, Tall A, Marrama L, Mercereau-Puijalon O, Richard V, Longacre S.

PLoS One. 2014 Jul 21;9(7):e101737. doi: 10.1371/journal.pone.0101737. eCollection 2014.


The rise and fall of malaria in a West African rural community, Dielmo, Senegal, from 1990 to 2012: a 22 year longitudinal study.

Trape JF, Tall A, Sokhna C, Ly AB, Diagne N, Ndiath O, Mazenot C, Richard V, Badiane A, Dieye-Ba F, Faye J, Ndiaye G, Diene Sarr F, Roucher C, Bouganali C, Bassène H, Touré-Baldé A, Roussilhon C, Perraut R, Spiegel A, Sarthou JL, da Silva LP, Mercereau-Puijalon O, Druilhe P, Rogier C.

Lancet Infect Dis. 2014 Jun;14(6):476-88. doi: 10.1016/S1473-3099(14)70712-1. Epub 2014 May 6.


Global analysis of Plasmodium falciparum Na(+)/H(+) exchanger (pfnhe-1) allele polymorphism and its usefulness as a marker of in vitro resistance to quinine.

Ménard D, Andriantsoanirina V, Khim N, Ratsimbasoa A, Witkowski B, Benedet C, Canier L, Mercereau-Puijalon O, Durand R.

Int J Parasitol Drugs Drug Resist. 2012 Oct 26;3:8-19. doi: 10.1016/j.ijpddr.2012.10.001. eCollection 2013 Dec. Review.


An exported kinase (FIKK4.2) that mediates virulence-associated changes in Plasmodium falciparum-infected red blood cells.

Kats LM, Fernandez KM, Glenister FK, Herrmann S, Buckingham DW, Siddiqui G, Sharma L, Bamert R, Lucet I, Guillotte M, Mercereau-Puijalon O, Cooke BM.

Int J Parasitol. 2014 Apr;44(5):319-28. doi: 10.1016/j.ijpara.2014.01.003. Epub 2014 Feb 14.


Reduced erythrocyte deformability associated with hypoargininemia during Plasmodium falciparum malaria.

Rey J, Buffet PA, Ciceron L, Milon G, Mercereau-Puijalon O, Safeukui I.

Sci Rep. 2014 Jan 20;4:3767. doi: 10.1038/srep03767.


A molecular marker of artemisinin-resistant Plasmodium falciparum malaria.

Ariey F, Witkowski B, Amaratunga C, Beghain J, Langlois AC, Khim N, Kim S, Duru V, Bouchier C, Ma L, Lim P, Leang R, Duong S, Sreng S, Suon S, Chuor CM, Bout DM, Ménard S, Rogers WO, Genton B, Fandeur T, Miotto O, Ringwald P, Le Bras J, Berry A, Barale JC, Fairhurst RM, Benoit-Vical F, Mercereau-Puijalon O, Ménard D.

Nature. 2014 Jan 2;505(7481):50-5. doi: 10.1038/nature12876. Epub 2013 Dec 18.


De novo assembly of a field isolate genome reveals novel Plasmodium vivax erythrocyte invasion genes.

Hester J, Chan ER, Menard D, Mercereau-Puijalon O, Barnwell J, Zimmerman PA, Serre D.

PLoS Negl Trop Dis. 2013 Dec 5;7(12):e2569. doi: 10.1371/journal.pntd.0002569. eCollection 2013.


Whole genome sequencing of field isolates reveals a common duplication of the Duffy binding protein gene in Malagasy Plasmodium vivax strains.

Menard D, Chan ER, Benedet C, Ratsimbasoa A, Kim S, Chim P, Do C, Witkowski B, Durand R, Thellier M, Severini C, Legrand E, Musset L, Nour BY, Mercereau-Puijalon O, Serre D, Zimmerman PA.

PLoS Negl Trop Dis. 2013 Nov 21;7(11):e2489. doi: 10.1371/journal.pntd.0002489. eCollection 2013 Nov.


A key role for Plasmodium subtilisin-like SUB1 protease in egress of malaria parasites from host hepatocytes.

Tawk L, Lacroix C, Gueirard P, Kent R, Gorgette O, Thiberge S, Mercereau-Puijalon O, Ménard R, Barale JC.

J Biol Chem. 2013 Nov 15;288(46):33336-46. doi: 10.1074/jbc.M113.513234. Epub 2013 Oct 2.


Novel phenotypic assays for the detection of artemisinin-resistant Plasmodium falciparum malaria in Cambodia: in-vitro and ex-vivo drug-response studies.

Witkowski B, Amaratunga C, Khim N, Sreng S, Chim P, Kim S, Lim P, Mao S, Sopha C, Sam B, Anderson JM, Duong S, Chuor CM, Taylor WR, Suon S, Mercereau-Puijalon O, Fairhurst RM, Menard D.

Lancet Infect Dis. 2013 Dec;13(12):1043-9. doi: 10.1016/S1473-3099(13)70252-4. Epub 2013 Sep 11.


Asthma and atopic dermatitis are associated with increased risk of clinical Plasmodium falciparum malaria.

Herrant M, Loucoubar C, Bassène H, Gonçalves B, Boufkhed S, Diene Sarr F, Fontanet A, Tall A, Baril L, Mercereau-Puijalon O, Mécheri S, Sakuntabhai A, Paul R.

BMJ Open. 2013 Jul 24;3(7). pii: e002835. doi: 10.1136/bmjopen-2013-002835. Print 2013.


[Plasmodium falciparum susceptibility to antimalarial drugs: global data issued from the Pasteur Institutes international network].

Ménard D, Ariey F, Mercereau-Puijalon O.

Med Sci (Paris). 2013 Jun-Jul;29(6-7):647-55. doi: 10.1051/medsci/2013296020. Epub 2013 Jul 12. Review. French.

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