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Results: 1 to 20 of 242

1.

Distinct methylation profiles characterize fusion-positive and fusion-negative rhabdomyosarcoma.

Sun W, Chatterjee B, Wang Y, Stevenson HS, Edelman DC, Meltzer PS, Barr FG.

Mod Pathol. 2015 Jul 31. doi: 10.1038/modpathol.2015.82. [Epub ahead of print]

PMID:
26226845
2.

miR-23a impairs bone differentiation in osteosarcoma via down-regulation of GJA1.

Gindin Y, Jiang Y, Francis P, Walker RL, Abaan OD, Zhu YJ, Meltzer PS.

Front Genet. 2015 Jul 2;6:233. doi: 10.3389/fgene.2015.00233. eCollection 2015.

3.

Erratum: Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jul 7;21(7):827. doi: 10.1038/nm0715-827a. No abstract available.

PMID:
26151328
4.

An Integrated Prognostic Classifier for Stage I Lung Adenocarcinoma Based on mRNA, microRNA, and DNA Methylation Biomarkers.

Robles AI, Arai E, Mathé EA, Okayama H, Schetter AJ, Brown D, Petersen D, Bowman ED, Noro R, Welsh JA, Edelman DC, Stevenson HS, Wang Y, Tsuchiya N, Kohno T, Skaug V, Mollerup S, Haugen A, Meltzer PS, Yokota J, Kanai Y, Harris CC.

J Thorac Oncol. 2015 Jul;10(7):1037-48. doi: 10.1097/JTO.0000000000000560.

PMID:
26134223
5.

A genome-wide scan identifies variants in NFIB associated with metastasis in patients with osteosarcoma.

Mirabello L, Koster R, Moriarity BS, Spector LG, Meltzer PS, Gary J, Machiela MJ, Pankratz N, Panagiotou OA, Largaespada D, Wang Z, Gastier-Foster JM, Gorlick R, Khanna C, Caminada de Toledo SR, Petrilli AS, Patino-Garcia A, Sierrasesumaga L, Lecanda F, Andrulis IL, Wunder JS, Gokgoz N, Serra M, Hattinger C, Picci P, Scotlandi K, Flanagan AM, Tirabosco R, Fernanda Amary M, Halai D, Ballinger ML, Thomas DM, Davis S, Barkauskas DA, Marina N, Helman L, Otto GM, Becklin KL, Wolf NK, Weg MT, Tucker M, Wacholder S, Fraumeni JF Jr, Caporaso NE, Boland JF, Hicks BD, Vogt A, Burdett L, Yeager M, Hoover RN, Chanock SJ, Savage SA.

Cancer Discov. 2015 Jun 17. pii: CD-15-0125. [Epub ahead of print]

PMID:
26084801
6.

Functionally defined therapeutic targets in diffuse intrinsic pontine glioma.

Grasso CS, Tang Y, Truffaux N, Berlow NE, Liu L, Debily MA, Quist MJ, Davis LE, Huang EC, Woo PJ, Ponnuswami A, Chen S, Johung TB, Sun W, Kogiso M, Du Y, Qi L, Huang Y, Hütt-Cabezas M, Warren KE, Le Dret L, Meltzer PS, Mao H, Quezado M, van Vuurden DG, Abraham J, Fouladi M, Svalina MN, Wang N, Hawkins C, Nazarian J, Alonso MM, Raabe EH, Hulleman E, Spellman PT, Li XN, Keller C, Pal R, Grill J, Monje M.

Nat Med. 2015 Jun;21(6):555-9. doi: 10.1038/nm.3855. Epub 2015 May 4.

PMID:
25939062
7.

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling.

Grøntved L, Waterfall JJ, Kim DW, Baek S, Sung MH, Zhao L, Park JW, Nielsen R, Walker RL, Zhu YJ, Meltzer PS, Hager GL, Cheng SY.

Nat Commun. 2015 Apr 28;6:7048. doi: 10.1038/ncomms8048.

PMID:
25916672
8.

SLFN11 is a transcriptional target of EWS-FLI1 and a determinant of drug response in Ewing's sarcoma.

Tang SW, Bilke S, Cao L, Murai J, Sousa FG, Yamade M, Rajapakse V, Varma S, Helman LJ, Khan J, Meltzer PS, Pommier Y.

Clin Cancer Res. 2015 Mar 16. pii: clincanres.2112.2014. [Epub ahead of print]

PMID:
25779942
9.

EWS-FLI1 employs an E2F switch to drive target gene expression.

Schwentner R, Papamarkou T, Kauer MO, Stathopoulos V, Yang F, Bilke S, Meltzer PS, Girolami M, Kovar H.

Nucleic Acids Res. 2015 Mar 11;43(5):2780-9. doi: 10.1093/nar/gkv123. Epub 2015 Feb 20.

10.

Avalanching mutations in biallelic mismatch repair deficiency syndrome.

Waterfall JJ, Meltzer PS.

Nat Genet. 2015 Mar;47(3):194-6. doi: 10.1038/ng.3227.

PMID:
25711864
11.

Molecular profiling and targeted therapy for advanced thoracic malignancies: a biomarker-derived, multiarm, multihistology phase II basket trial.

Lopez-Chavez A, Thomas A, Rajan A, Raffeld M, Morrow B, Kelly R, Carter CA, Guha U, Killian K, Lau CC, Abdullaev Z, Xi L, Pack S, Meltzer PS, Corless CL, Sandler A, Beadling C, Warrick A, Liewehr DJ, Steinberg SM, Berman A, Doyle A, Szabo E, Wang Y, Giaccone G.

J Clin Oncol. 2015 Mar 20;33(9):1000-7. doi: 10.1200/JCO.2014.58.2007. Epub 2015 Feb 9.

PMID:
25667274
12.

Recurrent epimutation of SDHC in gastrointestinal stromal tumors.

Killian JK, Miettinen M, Walker RL, Wang Y, Zhu YJ, Waterfall JJ, Noyes N, Retnakumar P, Yang Z, Smith WI Jr, Killian MS, Lau CC, Pineda M, Walling J, Stevenson H, Smith C, Wang Z, Lasota J, Kim SY, Boikos SA, Helman LJ, Meltzer PS.

Sci Transl Med. 2014 Dec 24;6(268):268ra177. doi: 10.1126/scitranslmed.3009961.

PMID:
25540324
13.

Building through breaking: the development of cancer neochromosomes.

Waterfall JJ, Meltzer PS.

Cancer Cell. 2014 Nov 10;26(5):593-5. doi: 10.1016/j.ccell.2014.10.013. Epub 2014 Nov 10.

PMID:
25517741
14.

Identification of RECQ1-regulated transcriptome uncovers a role of RECQ1 in regulation of cancer cell migration and invasion.

Li XL, Lu X, Parvathaneni S, Bilke S, Zhang H, Thangavel S, Vindigni A, Hara T, Zhu Y, Meltzer PS, Lal A, Sharma S.

Cell Cycle. 2014;13(15):2431-45. doi: 10.4161/cc.29419.

15.

Mutations of epigenetic regulatory genes are common in thymic carcinomas.

Wang Y, Thomas A, Lau C, Rajan A, Zhu Y, Killian JK, Petrini I, Pham T, Morrow B, Zhong X, Meltzer PS, Giaccone G.

Sci Rep. 2014 Dec 8;4:7336. doi: 10.1038/srep07336.

16.

Replicon: a software to accurately predict DNA replication timing in metazoan cells.

Gindin Y, Meltzer PS, Bilke S.

Front Genet. 2014 Nov 3;5:378. doi: 10.3389/fgene.2014.00378. eCollection 2014.

17.

Genetic and epigenetic analysis of monozygotic twins discordant for testicular cancer.

Kratz CP, Edelman DC, Wang Y, Meltzer PS, Greene MH.

Int J Mol Epidemiol Genet. 2014 Oct 22;5(3):135-9. eCollection 2014.

18.

The role of mutation of metabolism-related genes in genomic hypermethylation.

Waterfall JJ, Killian JK, Meltzer PS.

Biochem Biophys Res Commun. 2014 Dec 5;455(1-2):16-23. doi: 10.1016/j.bbrc.2014.08.003. Epub 2014 Aug 8. Review.

PMID:
25111818
19.

NCI-60 whole exome sequencing and pharmacological CellMiner analyses.

Reinhold WC, Varma S, Sousa F, Sunshine M, Abaan OD, Davis SR, Reinhold SW, Kohn KW, Morris J, Meltzer PS, Doroshow JH, Pommier Y.

PLoS One. 2014 Jul 17;9(7):e101670. doi: 10.1371/journal.pone.0101670. eCollection 2014.

20.

Lineage of origin in rhabdomyosarcoma informs pharmacological response.

Abraham J, Nuñez-Álvarez Y, Hettmer S, Carrió E, Chen HI, Nishijo K, Huang ET, Prajapati SI, Walker RL, Davis S, Rebeles J, Wiebush H, McCleish AT, Hampton ST, Bjornson CR, Brack AS, Wagers AJ, Rando TA, Capecchi MR, Marini FC, Ehler BR, Zarzabal LA, Goros MW, Michalek JE, Meltzer PS, Langenau DM, LeGallo RD, Mansoor A, Chen Y, Suelves M, Rubin BP, Keller C.

Genes Dev. 2014 Jul 15;28(14):1578-91. doi: 10.1101/gad.238733.114.

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