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Items: 1 to 20 of 145

1.

The cartilage extracellular matrix as a transient developmental scaffold for growth plate maturation.

Melrose J, Shu C, Whitelock JM, Lord MS.

Matrix Biol. 2016 Jan 23. pii: S0945-053X(16)30007-5. doi: 10.1016/j.matbio.2016.01.008. [Epub ahead of print] Review.

PMID:
26807757
2.

Perlecan domain I heparan sulfate ablation reduces progressive cartilage degradation, synovitis, and osteophyte size in post-traumatic osteoarthritis.

Shu CC, Jackson MT, Smith MM, Smith SM, Penm S, Lord MS, Whitelock JM, Little CB, Melrose J.

Arthritis Rheumatol. 2015 Dec 4. doi: 10.1002/art.39529. [Epub ahead of print]

PMID:
26636652
3.

Multifidus Muscle Changes After Back Injury Are Characterized by Structural Remodeling of Muscle, Adipose and Connective Tissue, but Not Muscle Atrophy: Molecular and Morphological Evidence.

Hodges PW, James G, Blomster L, Hall L, Schmid A, Shu C, Little C, Melrose J.

Spine (Phila Pa 1976). 2015 Jul 15;40(14):1057-71. doi: 10.1097/BRS.0000000000000972.

PMID:
25943090
4.

Proteoglycans in Normal and Healing Skin.

Smith MM, Melrose J.

Adv Wound Care (New Rochelle). 2015 Mar 1;4(3):152-173.

5.

Increased ventral-striatal activity during monetary decision making is a marker of problem poker gambling severity.

Brevers D, Noël X, He Q, Melrose JA, Bechara A.

Addict Biol. 2015 Mar 17. doi: 10.1111/adb.12239. [Epub ahead of print]

PMID:
25781641
6.

Can we produce heparin/heparan sulfate biomimetics using "mother-nature" as the gold standard?

Farrugia BL, Lord MS, Melrose J, Whitelock JM.

Molecules. 2015 Mar 5;20(3):4254-76. doi: 10.3390/molecules20034254. Review.

7.

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

Hayes AJ, Gibson MA, Shu C, Melrose J.

Tissue Cell. 2014 Jun;46(3):185-97. doi: 10.1016/j.tice.2014.04.002. Epub 2014 May 6.

PMID:
24867584
8.

Can proinflammatory cytokine gene expression explain multifidus muscle fiber changes after an intervertebral disc lesion?

Hodges PW, James G, Blomster L, Hall L, Schmid AB, Shu C, Little C, Melrose J.

Spine (Phila Pa 1976). 2014 Jun 1;39(13):1010-7. doi: 10.1097/BRS.0000000000000318.

PMID:
24718080
9.

The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.

Lord MS, Chuang CY, Melrose J, Davies MJ, Iozzo RV, Whitelock JM.

Matrix Biol. 2014 Apr;35:112-22. doi: 10.1016/j.matbio.2014.01.016. Epub 2014 Feb 6.

PMID:
24509440
10.

The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc.

Shu C, Hughes C, Smith SM, Smith MM, Hayes A, Caterson B, Little CB, Melrose J.

Glycoconj J. 2013 Oct;30(7):717-25. doi: 10.1007/s10719-013-9475-9. Epub 2013 Jun 13.

PMID:
23756834
11.

Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation.

Melton AC, Melrose J, Alajoki L, Privat S, Cho H, Brown N, Plavec AM, Nguyen D, Johnston ED, Yang J, Polokoff MA, Plavec I, Berg EL, O'Mahony A.

PLoS One. 2013;8(3):e58966. doi: 10.1371/journal.pone.0058966. Epub 2013 Mar 7.

13.

Altered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathy.

Melrose J, Smith MM, Smith SM, Ravi V, Young AA, Dart AJ, Sonnabend DH, Little CB.

Tissue Cell. 2013 Feb;45(1):77-82. doi: 10.1016/j.tice.2012.10.001. Epub 2012 Dec 12.

PMID:
23245384
14.

Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.

Hayes AJ, Smith SM, Melrose J.

Histochem Cell Biol. 2013 Jan;139(1):1-11. doi: 10.1007/s00418-012-1041-1. Epub 2012 Oct 27.

PMID:
23104139
15.

Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development.

Melrose J, Isaacs MD, Smith SM, Hughes CE, Little CB, Caterson B, Hayes AJ.

Histochem Cell Biol. 2012 Sep;138(3):461-75. doi: 10.1007/s00418-012-0968-6. Epub 2012 May 23.

PMID:
22617995
16.

The cartilage matrix molecule components produced by human foetal cartilage rudiment cells within scaffolds and the role of exogenous growth factors.

Chuang CY, Shahin K, Lord MS, Melrose J, Doran PM, Whitelock JM.

Biomaterials. 2012 Jun;33(16):4078-88. doi: 10.1016/j.biomaterials.2012.02.032. Epub 2012 Mar 3.

PMID:
22391264
17.

A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs.

Brown S, Melrose J, Caterson B, Roughley P, Eisenstein SM, Roberts S.

Eur Spine J. 2012 May;21 Suppl 2:S154-9. doi: 10.1007/s00586-012-2179-1. Epub 2012 Feb 23.

18.

Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.

Melrose J, Shu C, Young C, Ho R, Smith MM, Young AA, Smith SS, Gooden B, Dart A, Podadera J, Appleyard RC, Little CB.

Spine (Phila Pa 1976). 2012 Jan 1;37(1):18-25. doi: 10.1097/BRS.0b013e31820cd8d5.

PMID:
22179320
19.

Zonal differences in meniscus matrix turnover and cytokine response.

Fuller ES, Smith MM, Little CB, Melrose J.

Osteoarthritis Cartilage. 2012 Jan;20(1):49-59. doi: 10.1016/j.joca.2011.10.002. Epub 2011 Oct 24.

20.

Proteoglycan degradation by the ADAMTS family of proteinases.

Stanton H, Melrose J, Little CB, Fosang AJ.

Biochim Biophys Acta. 2011 Dec;1812(12):1616-29. doi: 10.1016/j.bbadis.2011.08.009. Epub 2011 Sep 2. Review.

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