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Results: 1 to 20 of 139

1.

Confocal microscopy demonstrates association of LTBP-2 in fibrillin-1 microfibrils and colocalisation with perlecan in the disc cell pericellular matrix.

Hayes AJ, Gibson MA, Shu C, Melrose J.

Tissue Cell. 2014 Jun;46(3):185-97. doi: 10.1016/j.tice.2014.04.002. Epub 2014 May 6.

PMID:
24867584
[PubMed - in process]
2.

Can proinflammatory cytokine gene expression explain multifidus muscle fiber changes after an intervertebral disc lesion?

Hodges PW, James G, Blomster L, Hall L, Schmid AB, Shu C, Little C, Melrose J.

Spine (Phila Pa 1976). 2014 Jun 1;39(13):1010-7. doi: 10.1097/BRS.0000000000000318.

PMID:
24718080
[PubMed - in process]
3.

The role of vascular-derived perlecan in modulating cell adhesion, proliferation and growth factor signaling.

Lord MS, Chuang CY, Melrose J, Davies MJ, Iozzo RV, Whitelock JM.

Matrix Biol. 2014 Apr;35:112-22. doi: 10.1016/j.matbio.2014.01.016. Epub 2014 Feb 6.

PMID:
24509440
[PubMed - in process]
Free Article
4.

The ovine newborn and human foetal intervertebral disc contain perlecan and aggrecan variably substituted with native 7D4 CS sulphation motif: spatiotemporal immunolocalisation and co-distribution with Notch-1 in the human foetal disc.

Shu C, Hughes C, Smith SM, Smith MM, Hayes A, Caterson B, Little CB, Melrose J.

Glycoconj J. 2013 Oct;30(7):717-25. doi: 10.1007/s10719-013-9475-9. Epub 2013 Jun 13.

PMID:
23756834
[PubMed - indexed for MEDLINE]
5.

Regulation of IL-17A production is distinct from IL-17F in a primary human cell co-culture model of T cell-mediated B cell activation.

Melton AC, Melrose J, Alajoki L, Privat S, Cho H, Brown N, Plavec AM, Nguyen D, Johnston ED, Yang J, Polokoff MA, Plavec I, Berg EL, O'Mahony A.

PLoS One. 2013;8(3):e58966. doi: 10.1371/journal.pone.0058966. Epub 2013 Mar 7.

PMID:
23505568
[PubMed - indexed for MEDLINE]
Free PMC Article
6.
7.

Altered stress induced by partial transection of the infraspinatus tendon leads to perlecan (HSPG2) accumulation in an ovine model of tendinopathy.

Melrose J, Smith MM, Smith SM, Ravi V, Young AA, Dart AJ, Sonnabend DH, Little CB.

Tissue Cell. 2013 Feb;45(1):77-82. doi: 10.1016/j.tice.2012.10.001. Epub 2012 Dec 12.

PMID:
23245384
[PubMed - indexed for MEDLINE]
8.

Comparative immunolocalisation of fibrillin-1 and perlecan in the human foetal, and HS-deficient hspg2 exon 3 null mutant mouse intervertebral disc.

Hayes AJ, Smith SM, Melrose J.

Histochem Cell Biol. 2013 Jan;139(1):1-11. doi: 10.1007/s00418-012-1041-1. Epub 2012 Oct 27.

PMID:
23104139
[PubMed - indexed for MEDLINE]
9.

Chondroitin sulphate and heparan sulphate sulphation motifs and their proteoglycans are involved in articular cartilage formation during human foetal knee joint development.

Melrose J, Isaacs MD, Smith SM, Hughes CE, Little CB, Caterson B, Hayes AJ.

Histochem Cell Biol. 2012 Sep;138(3):461-75. doi: 10.1007/s00418-012-0968-6. Epub 2012 May 23.

PMID:
22617995
[PubMed - indexed for MEDLINE]
10.

The cartilage matrix molecule components produced by human foetal cartilage rudiment cells within scaffolds and the role of exogenous growth factors.

Chuang CY, Shahin K, Lord MS, Melrose J, Doran PM, Whitelock JM.

Biomaterials. 2012 Jun;33(16):4078-88. doi: 10.1016/j.biomaterials.2012.02.032. Epub 2012 Mar 3.

PMID:
22391264
[PubMed - indexed for MEDLINE]
11.

A comparative evaluation of the small leucine-rich proteoglycans of pathological human intervertebral discs.

Brown S, Melrose J, Caterson B, Roughley P, Eisenstein SM, Roberts S.

Eur Spine J. 2012 May;21 Suppl 2:S154-9. doi: 10.1007/s00586-012-2179-1. Epub 2012 Feb 23.

PMID:
22358337
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Mechanical destabilization induced by controlled annular incision of the intervertebral disc dysregulates metalloproteinase expression and induces disc degeneration.

Melrose J, Shu C, Young C, Ho R, Smith MM, Young AA, Smith SS, Gooden B, Dart A, Podadera J, Appleyard RC, Little CB.

Spine (Phila Pa 1976). 2012 Jan 1;37(1):18-25. doi: 10.1097/BRS.0b013e31820cd8d5.

PMID:
22179320
[PubMed - indexed for MEDLINE]
13.

Zonal differences in meniscus matrix turnover and cytokine response.

Fuller ES, Smith MM, Little CB, Melrose J.

Osteoarthritis Cartilage. 2012 Jan;20(1):49-59. doi: 10.1016/j.joca.2011.10.002. Epub 2011 Oct 24.

PMID:
22062355
[PubMed - indexed for MEDLINE]
Free Article
14.

Proteoglycan degradation by the ADAMTS family of proteinases.

Stanton H, Melrose J, Little CB, Fosang AJ.

Biochim Biophys Acta. 2011 Dec;1812(12):1616-29. doi: 10.1016/j.bbadis.2011.08.009. Epub 2011 Sep 2. Review.

PMID:
21914474
[PubMed - indexed for MEDLINE]
Free Article
15.

Colocalization in vivo and association in vitro of perlecan and elastin.

Hayes AJ, Lord MS, Smith SM, Smith MM, Whitelock JM, Weiss AS, Melrose J.

Histochem Cell Biol. 2011 Oct;136(4):437-54. doi: 10.1007/s00418-011-0854-7. Epub 2011 Aug 28.

PMID:
21874555
[PubMed - indexed for MEDLINE]
16.

Comparative immunolocalization of the elastin fiber-associated proteins fibrillin-1, LTBP-2, and MAGP-1 with components of the collagenous and proteoglycan matrix of the fetal human intervertebral disc.

Hayes AJ, Smith SM, Gibson MA, Melrose J.

Spine (Phila Pa 1976). 2011 Oct 1;36(21):E1365-72. doi: 10.1097/BRS.0b013e31821fd23e.

PMID:
21540769
[PubMed - indexed for MEDLINE]
17.

Heparan sulfate proteoglycans in healthy and diseased systems.

Whitelock J, Melrose J.

Wiley Interdiscip Rev Syst Biol Med. 2011 Nov-Dec;3(6):739-51. doi: 10.1002/wsbm.149. Epub 2011 Apr 1.

PMID:
21462353
[PubMed - indexed for MEDLINE]
18.

Podoplanin is expressed by a sub-population of human foetal rib and knee joint rudiment chondrocytes.

Smith SM, Melrose J.

Tissue Cell. 2011 Feb;43(1):39-44. doi: 10.1016/j.tice.2010.11.003. Epub 2010 Dec 24.

PMID:
21185581
[PubMed - indexed for MEDLINE]
19.

A detailed microscopic examination of alterations in normal anular structure induced by mechanical destabilization in an ovine model of disc degeneration.

Schollum ML, Appleyard RC, Little CB, Melrose J.

Spine (Phila Pa 1976). 2010 Oct 15;35(22):1965-73. doi: 10.1097/BRS.0b013e3181e0f085.

PMID:
20959777
[PubMed - indexed for MEDLINE]
20.

Comparative immunolocalisation of perlecan with collagen II and aggrecan in human foetal, newborn and adult ovine joint tissues demonstrates perlecan as an early developmental chondrogenic marker.

Smith SM, Shu C, Melrose J.

Histochem Cell Biol. 2010 Sep;134(3):251-63. doi: 10.1007/s00418-010-0730-x. Epub 2010 Aug 6.

PMID:
20690028
[PubMed - indexed for MEDLINE]

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