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Results: 1 to 20 of 81


POS-1 Promotes Endo-mesoderm Development by Inhibiting the Cytoplasmic Polyadenylation of neg-1 mRNA.

Elewa A, Shirayama M, Kaymak E, Harrison PF, Powell DR, Du Z, Chute CD, Woolf H, Yi D, Ishidate T, Srinivasan J, Bao Z, Beilharz TH, Ryder SP, Mello CC.

Dev Cell. 2015 Jun 17. pii: S1534-5807(15)00360-3. doi: 10.1016/j.devcel.2015.05.024. [Epub ahead of print]


RNA interference-mediated antiviral defense in insects.

Gammon DB, Mello CC.

Curr Opin Insect Sci. 2015 Apr 1;8:111-120.


Suppression of pervasive noncoding transcription in embryonic stem cells by esBAF.

Hainer SJ, Gu W, Carone BR, Landry BD, Rando OJ, Mello CC, Fazzio TG.

Genes Dev. 2015 Feb 15;29(4):362-78. doi: 10.1101/gad.253534.114.


A ribonuclease coordinates siRNA amplification and mRNA cleavage during RNAi.

Tsai HY, Chen CC, Conte D Jr, Moresco JJ, Chaves DA, Mitani S, Yates JR 3rd, Tsai MD, Mello CC.

Cell. 2015 Jan 29;160(3):407-19. doi: 10.1016/j.cell.2015.01.010.


RNA Interference in Caenorhabditis elegans.

Conte D Jr, MacNeil LT, Walhout AJ, Mello CC.

Curr Protoc Mol Biol. 2015 Jan 5;109:26.3.1-26.3.30. doi: 10.1002/0471142727.mb2603s109.


A single vertebrate DNA virus protein disarms invertebrate immunity to RNA virus infection.

Gammon DB, Duraffour S, Rozelle DK, Hehnly H, Sharma R, Sparks ME, West CC, Chen Y, Moresco JJ, Andrei G, Connor JH, Conte D Jr, Gundersen-Rindal DE, Marshall WL, Yates JR, Silverman N, Mello CC.

Elife. 2014 Jun 25;3. doi: 10.7554/eLife.02910.


A co-CRISPR strategy for efficient genome editing in Caenorhabditis elegans.

Kim H, Ishidate T, Ghanta KS, Seth M, Conte D Jr, Shirayama M, Mello CC.

Genetics. 2014 Aug;197(4):1069-80. doi: 10.1534/genetics.114.166389. Epub 2014 May 30.


The Vasa Homolog RDE-12 engages target mRNA and multiple argonaute proteins to promote RNAi in C. elegans.

Shirayama M, Stanney W 3rd, Gu W, Seth M, Mello CC.

Curr Biol. 2014 Apr 14;24(8):845-51. doi: 10.1016/j.cub.2014.03.008. Epub 2014 Mar 27.


Divide and differentiate: CDK/Cyclins and the art of development.

Ishidate T, Elewa A, Kim S, Mello CC, Shirayama M.

Cell Cycle. 2014;13(9):1384-91. doi: 10.4161/cc.28656. Epub 2014 Mar 26. Review.


The C. elegans CSR-1 argonaute pathway counteracts epigenetic silencing to promote germline gene expression.

Seth M, Shirayama M, Gu W, Ishidate T, Conte D Jr, Mello CC.

Dev Cell. 2013 Dec 23;27(6):656-63.


Argonautes promote male fertility and provide a paternal memory of germline gene expression in C. elegans.

Conine CC, Moresco JJ, Gu W, Shirayama M, Conte D Jr, Yates JR 3rd, Mello CC.

Cell. 2013 Dec 19;155(7):1532-44. doi: 10.1016/j.cell.2013.11.032.


Wnt and CDK-1 regulate cortical release of WRM-1/β-catenin to control cell division orientation in early Caenorhabditis elegans embryos.

Kim S, Ishidate T, Sharma R, Soto MC, Conte D Jr, Mello CC, Shirayama M.

Proc Natl Acad Sci U S A. 2013 Mar 5;110(10):E918-27. doi: 10.1073/pnas.1300769110. Epub 2013 Feb 19.


CapSeq and CIP-TAP identify Pol II start sites and reveal capped small RNAs as C. elegans piRNA precursors.

Gu W, Lee HC, Chaves D, Youngman EM, Pazour GJ, Conte D Jr, Mello CC.

Cell. 2012 Dec 21;151(7):1488-500. doi: 10.1016/j.cell.2012.11.023.


Specific miRNA stabilization by Gld2-catalyzed monoadenylation.

D'Ambrogio A, Gu W, Udagawa T, Mello CC, Richter JD.

Cell Rep. 2012 Dec 27;2(6):1537-45. doi: 10.1016/j.celrep.2012.10.023. Epub 2012 Nov 29.


Protection from feed-forward amplification in an amplified RNAi mechanism.

Pak J, Maniar JM, Mello CC, Fire A.

Cell. 2012 Nov 9;151(4):885-99. doi: 10.1016/j.cell.2012.10.022.


The translin-TRAX complex (C3PO) is a ribonuclease in tRNA processing.

Li L, Gu W, Liang C, Liu Q, Mello CC, Liu Y.

Nat Struct Mol Biol. 2012 Aug;19(8):824-30. doi: 10.1038/nsmb.2337. Epub 2012 Jul 8.


piRNAs initiate an epigenetic memory of nonself RNA in the C. elegans germline.

Shirayama M, Seth M, Lee HC, Gu W, Ishidate T, Conte D Jr, Mello CC.

Cell. 2012 Jul 6;150(1):65-77. doi: 10.1016/j.cell.2012.06.015. Epub 2012 Jun 25.


C. elegans piRNAs mediate the genome-wide surveillance of germline transcripts.

Lee HC, Gu W, Shirayama M, Youngman E, Conte D Jr, Mello CC.

Cell. 2012 Jul 6;150(1):78-87. doi: 10.1016/j.cell.2012.06.016. Epub 2012 Jun 25.


Tudor domain ERI-5 tethers an RNA-dependent RNA polymerase to DCR-1 to potentiate endo-RNAi.

Thivierge C, Makil N, Flamand M, Vasale JJ, Mello CC, Wohlschlegel J, Conte D Jr, Duchaine TF.

Nat Struct Mol Biol. 2011 Dec 18;19(1):90-7. doi: 10.1038/nsmb.2186. Erratum in: Nat Struct Mol Biol. 2013 Feb;20(2):244.


Cloning Argonaute-associated small RNAs from Caenorhabditis elegans.

Gu W, Claycomb JM, Batista PJ, Mello CC, Conte D.

Methods Mol Biol. 2011;725:251-80. doi: 10.1007/978-1-61779-046-1_17.

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