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Results: 1 to 20 of 212


Circulating serum miRNAs as potential biomarkers for nephroblastoma.

Ludwig N, Nourkami-Tutdibi N, Backes C, Lenhof HP, Graf N, Keller A, Meese E.

Pediatr Blood Cancer. 2015 Mar 18. doi: 10.1002/pbc.25481. [Epub ahead of print]


Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo.

Fischer U, Backes C, Raslan A, Keller A, Meier C, Meese E.

Oncotarget. 2015 Mar 30;6(9):7023-39.


HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues.

Schmitt K, Heyne K, Roemer K, Meese E, Mayer J.

Mob DNA. 2015 Mar 5;6:4. doi: 10.1186/s13100-015-0035-7. eCollection 2015.


Circulating Biomarker Panels in Alzheimer's Disease.

Zafari S, Backes C, Meese E, Keller A.

Gerontology. 2015 Feb 25. [Epub ahead of print]


Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs.

Ludwig N, Kim YJ, Mueller SC, Backes C, Werner TV, Galata V, Sartorius E, Bohle RM, Keller A, Meese E.

Neuro Oncol. 2015 Feb 13. pii: nov014. [Epub ahead of print]


Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, Keller A, Grimm C, Kneitz S, Williams RD, Chagtai T, Pritchard-Jones K, van Sluis P, Volckmann R, Koster J, Versteeg R, Acha T, O'Sullivan MJ, Bode PK, Niggli F, Tytgat GA, van Tinteren H, van den Heuvel-Eibrink MM, Meese E, Vokuhl C, Leuschner I, Graf N, Eils R, Pfister SM, Kool M, Gessler M.

Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.


A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis.

Latorre I, Leidinger P, Backes C, Domínguez J, de Souza-Galvão ML, Maldonado J, Prat C, Ruiz-Manzano J, Sánchez F, Casas I, Keller A, von Briesen H, Knobel H, Meese E, Meyerhans A.

Eur Respir J. 2015 Apr;45(4):1173-6. doi: 10.1183/09031936.00221514. Epub 2015 Feb 5. No abstract available.


Pathogenicity prediction of non-synonymous single nucleotide variants in dilated cardiomyopathy.

Mueller SC, Backes C, Haas J The Inheritance Study Group, Katus HA, Meder B, Meese E, Keller A.

Brief Bioinform. 2015 Jan 30. pii: bbu054. [Epub ahead of print]


MicroRNA In Vitro Diagnostics Using Immunoassay Analyzers.

Kappel A, Backes C, Huang Y, Zafari S, Leidinger P, Meder B, Schwarz H, Gumbrecht W, Meese E, Staehler CF, Keller A.

Clin Chem. 2015 Apr;61(4):600-7. doi: 10.1373/clinchem.2014.232165. Epub 2015 Jan 23.


New insights into the genetics of glioblastoma multiforme by familial exome sequencing.

Backes C, Harz C, Fischer U, Schmitt J, Ludwig N, Petersen BS, Mueller SC, Kim YJ, Wolf NM, Katus HA, Meder B, Furtwängler R, Franke A, Bohle R, Henn W, Graf N, Keller A, Meese E.

Oncotarget. 2015 Mar 20;6(8):5918-31.


Differentially regulated miRNAs as prognostic biomarkers in the blood of primary CNS lymphoma patients.

Roth P, Keller A, Hoheisel JD, Codo P, Bauer AS, Backes C, Leidinger P, Meese E, Thiel E, Korfel A, Weller M.

Eur J Cancer. 2015 Feb;51(3):382-90. doi: 10.1016/j.ejca.2014.10.028. Epub 2014 Dec 17.


miRNAs can be generally associated with human pathologies as exemplified for miR-144.

Keller A, Leidinger P, Vogel B, Backes C, ElSharawy A, Galata V, Mueller SC, Marquart S, Schrauder MG, Strick R, Bauer A, Wischhusen J, Beier M, Kohlhaas J, Katus HA, Hoheisel J, Franke A, Meder B, Meese E.

BMC Med. 2014 Dec 3;12(1):224.


What makes a blood cell based miRNA expression pattern disease specific?--a miRNome analysis of blood cell subsets in lung cancer patients and healthy controls.

Leidinger P, Backes C, Dahmke IN, Galata V, Huwer H, Stehle I, Bals R, Keller A, Meese E.

Oncotarget. 2014 Oct 15;5(19):9484-97.


The blood-borne miRNA signature of lung cancer patients is independent of histology but influenced by metastases.

Leidinger P, Backes C, Blatt M, Keller A, Huwer H, Lepper P, Bals R, Meese E.

Mol Cancer. 2014 Aug 30;13:202. doi: 10.1186/1476-4598-13-202.


Secretion and immunogenicity of the meningioma-associated antigen TXNDC16.

Harz C, Ludwig N, Lang S, Werner TV, Galata V, Backes C, Schmitt K, Nickels R, Krause E, Jung M, Rettig J, Keller A, Menger M, Zimmermann R, Meese E.

J Immunol. 2014 Sep 15;193(6):3146-54. doi: 10.4049/jimmunol.1303098. Epub 2014 Aug 13.


Panel of five microRNAs as potential biomarkers for the diagnosis and assessment of male infertility.

Abu-Halima M, Hammadeh M, Backes C, Fischer U, Leidinger P, Lubbad AM, Keller A, Meese E.

Fertil Steril. 2014 Oct;102(4):989-997.e1. doi: 10.1016/j.fertnstert.2014.07.001. Epub 2014 Aug 6.


Systematic permutation testing in GWAS pathway analyses: identification of genetic networks in dilated cardiomyopathy and ulcerative colitis.

Backes C, Rühle F, Stoll M, Haas J, Frese K, Franke A, Lieb W, Wichmann HE, Weis T, Kloos W, Lenhof HP, Meese E, Katus H, Meder B, Keller A.

BMC Genomics. 2014 Jul 22;15:622. doi: 10.1186/1471-2164-15-622.


Blood born miRNAs signatures that can serve as disease specific biomarkers are not significantly affected by overall fitness and exercise.

Backes C, Leidinger P, Keller A, Hart M, Meyer T, Meese E, Hecksteden A.

PLoS One. 2014 Jul 10;9(7):e102183. doi: 10.1371/journal.pone.0102183. eCollection 2014.


Influence of the confounding factors age and sex on microRNA profiles from peripheral blood.

Meder B, Backes C, Haas J, Leidinger P, Stähler C, Großmann T, Vogel B, Frese K, Giannitsis E, Katus HA, Meese E, Keller A.

Clin Chem. 2014 Sep;60(9):1200-8. doi: 10.1373/clinchem.2014.224238. Epub 2014 Jun 30.


The human miRNA repertoire of different blood compounds.

Leidinger P, Backes C, Meder B, Meese E, Keller A.

BMC Genomics. 2014 Jun 14;15:474. doi: 10.1186/1471-2164-15-474.

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