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Results: 1 to 20 of 218


Influence of Next-Generation Sequencing and Storage Conditions on miRNA Patterns Generated from PAXgene Blood.

Backes C, Leidinger P, Altmann G, Wuerstle M, Meder B, Galata V, Mueller SC, Sickert D, Stähler C, Meese E, Keller A.

Anal Chem. 2015 Sep 1;87(17):8910-6. doi: 10.1021/acs.analchem.5b02043. Epub 2015 Aug 10.


BALL-SNP: combining genetic and structural information to identify candidate non-synonymous single nucleotide polymorphisms.

Mueller SC, Backes C, Kalinina OV, Meder B, Stöckel D, Lenhof HP, Meese E, Keller A.

Genome Med. 2015 Jul 1;7(1):65. doi: 10.1186/s13073-015-0190-y. eCollection 2015.


miFRame: analysis and visualization of miRNA sequencing data in neurological disorders.

Backes C, Haas J, Leidinger P, Frese K, Großmann T, Ruprecht K, Meder B, Meese E, Keller A.

J Transl Med. 2015 Jul 14;13:224. doi: 10.1186/s12967-015-0594-x.


Regulatory MicroRNA Networks: Complex Patterns of Target Pathways for Disease-related and Housekeeping MicroRNAs.

Zafari S, Backes C, Leidinger P, Meese E, Keller A.

Genomics Proteomics Bioinformatics. 2015 Jun;13(3):159-68. doi: 10.1016/j.gpb.2015.02.004. Epub 2015 Jul 11.


Longitudinal study on circulating miRNAs in patients after lung cancer resection.

Leidinger P, Galata V, Backes C, Stähler C, Rheinheimer S, Huwer H, Meese E, Keller A.

Oncotarget. 2015 Jun 30;6(18):16674-85.


Combination of Autoantibody Signature with PSA Level Enables a Highly Accurate Blood-Based Differentiation of Prostate Cancer Patients from Patients with Benign Prostatic Hyperplasia.

Leidinger P, Keller A, Milchram L, Harz C, Hart M, Werth A, Lenhof HP, Weinhäusel A, Keck B, Wullich B, Ludwig N, Meese E.

PLoS One. 2015 Jun 3;10(6):e0128235. doi: 10.1371/journal.pone.0128235. eCollection 2015.


Circulating serum miRNAs as potential biomarkers for nephroblastoma.

Ludwig N, Nourkami-Tutdibi N, Backes C, Lenhof HP, Graf N, Keller A, Meese E.

Pediatr Blood Cancer. 2015 Aug;62(8):1360-7. doi: 10.1002/pbc.25481. Epub 2015 Mar 18.


Gene amplification during differentiation of mammalian neural stem cells in vitro and in vivo.

Fischer U, Backes C, Raslan A, Keller A, Meier C, Meese E.

Oncotarget. 2015 Mar 30;6(9):7023-39.


HERV-K(HML-2) rec and np9 transcripts not restricted to disease but present in many normal human tissues.

Schmitt K, Heyne K, Roemer K, Meese E, Mayer J.

Mob DNA. 2015 Mar 5;6:4. doi: 10.1186/s13100-015-0035-7. eCollection 2015.


Circulating Biomarker Panels in Alzheimer's Disease.

Zafari S, Backes C, Meese E, Keller A.

Gerontology. 2015 Feb 25. [Epub ahead of print]


Posttranscriptional deregulation of signaling pathways in meningioma subtypes by differential expression of miRNAs.

Ludwig N, Kim YJ, Mueller SC, Backes C, Werner TV, Galata V, Sartorius E, Bohle RM, Keller A, Meese E.

Neuro Oncol. 2015 Sep;17(9):1250-60. doi: 10.1093/neuonc/nov014. Epub 2015 Feb 13.


Mutations in the SIX1/2 pathway and the DROSHA/DGCR8 miRNA microprocessor complex underlie high-risk blastemal type Wilms tumors.

Wegert J, Ishaque N, Vardapour R, Geörg C, Gu Z, Bieg M, Ziegler B, Bausenwein S, Nourkami N, Ludwig N, Keller A, Grimm C, Kneitz S, Williams RD, Chagtai T, Pritchard-Jones K, van Sluis P, Volckmann R, Koster J, Versteeg R, Acha T, O'Sullivan MJ, Bode PK, Niggli F, Tytgat GA, van Tinteren H, van den Heuvel-Eibrink MM, Meese E, Vokuhl C, Leuschner I, Graf N, Eils R, Pfister SM, Kool M, Gessler M.

Cancer Cell. 2015 Feb 9;27(2):298-311. doi: 10.1016/j.ccell.2015.01.002.


A novel whole-blood miRNA signature for a rapid diagnosis of pulmonary tuberculosis.

Latorre I, Leidinger P, Backes C, Domínguez J, de Souza-Galvão ML, Maldonado J, Prat C, Ruiz-Manzano J, Sánchez F, Casas I, Keller A, von Briesen H, Knobel H, Meese E, Meyerhans A.

Eur Respir J. 2015 Apr;45(4):1173-6. doi: 10.1183/09031936.00221514. Epub 2015 Feb 5. No abstract available.


Pathogenicity prediction of non-synonymous single nucleotide variants in dilated cardiomyopathy.

Mueller SC, Backes C, Haas J The Inheritance Study Group, Katus HA, Meder B, Meese E, Keller A.

Brief Bioinform. 2015 Jan 30. pii: bbu054. [Epub ahead of print]


MicroRNA in vitro diagnostics using immunoassay analyzers.

Kappel A, Backes C, Huang Y, Zafari S, Leidinger P, Meder B, Schwarz H, Gumbrecht W, Meese E, Staehler CF, Keller A.

Clin Chem. 2015 Apr;61(4):600-7. doi: 10.1373/clinchem.2014.232165. Epub 2015 Jan 23.


New insights into the genetics of glioblastoma multiforme by familial exome sequencing.

Backes C, Harz C, Fischer U, Schmitt J, Ludwig N, Petersen BS, Mueller SC, Kim YJ, Wolf NM, Katus HA, Meder B, Furtwängler R, Franke A, Bohle R, Henn W, Graf N, Keller A, Meese E.

Oncotarget. 2015 Mar 20;6(8):5918-31.


Differentially regulated miRNAs as prognostic biomarkers in the blood of primary CNS lymphoma patients.

Roth P, Keller A, Hoheisel JD, Codo P, Bauer AS, Backes C, Leidinger P, Meese E, Thiel E, Korfel A, Weller M.

Eur J Cancer. 2015 Feb;51(3):382-90. doi: 10.1016/j.ejca.2014.10.028. Epub 2014 Dec 17.


miRNAs can be generally associated with human pathologies as exemplified for miR-144.

Keller A, Leidinger P, Vogel B, Backes C, ElSharawy A, Galata V, Mueller SC, Marquart S, Schrauder MG, Strick R, Bauer A, Wischhusen J, Beier M, Kohlhaas J, Katus HA, Hoheisel J, Franke A, Meder B, Meese E.

BMC Med. 2014 Dec 3;12:224. doi: 10.1186/s12916-014-0224-0.


What makes a blood cell based miRNA expression pattern disease specific?--a miRNome analysis of blood cell subsets in lung cancer patients and healthy controls.

Leidinger P, Backes C, Dahmke IN, Galata V, Huwer H, Stehle I, Bals R, Keller A, Meese E.

Oncotarget. 2014 Oct 15;5(19):9484-97.


The blood-borne miRNA signature of lung cancer patients is independent of histology but influenced by metastases.

Leidinger P, Backes C, Blatt M, Keller A, Huwer H, Lepper P, Bals R, Meese E.

Mol Cancer. 2014 Aug 30;13:202. doi: 10.1186/1476-4598-13-202.

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