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Results: 1 to 20 of 66


Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky A, Quaggin S, Vainio SJ.

Exp Cell Res. 2015 Mar 15;332(2):163-78. doi: 10.1016/j.yexcr.2015.01.010. Epub 2015 Jan 30.


In search of human hematopoietic stem cell identity.

Ivanovs A, Medvinsky A.

Cell Stem Cell. 2015 Jan 8;16(1):5-6. doi: 10.1016/j.stem.2014.12.010.


On human development: lessons from stem cell systems.

Medvinsky A, Livesey FJ.

Development. 2015 Jan 1;142(1):17-20. doi: 10.1242/dev.114868.


Directed differentiation of embryonic stem cells using a bead-based combinatorial screening method.

Tarunina M, Hernandez D, Johnson CJ, Rybtsov S, Ramathas V, Jeyakumar M, Watson T, Hook L, Medvinsky A, Mason C, Choo Y.

PLoS One. 2014 Sep 24;9(9):e104301. doi: 10.1371/journal.pone.0104301. eCollection 2014.


Tracing the origin of the HSC hierarchy reveals an SCF-dependent, IL-3-independent CD43(-) embryonic precursor.

Rybtsov S, Batsivari A, Bilotkach K, Paruzina D, Senserrich J, Nerushev O, Medvinsky A.

Stem Cell Reports. 2014 Sep 9;3(3):489-501. doi: 10.1016/j.stemcr.2014.07.009. Epub 2014 Aug 28.


Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.

Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, de Bruijn M, Buchholz F, Gordon-Keylock S, Zhao S, Medvinsky A.

Development. 2014 Sep;141(17):3319-23. doi: 10.1242/dev.110841.


A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK, Kile BT, Medvinsky A, Alexander WS, Hilton DJ, Taoudi S.

Blood. 2014 Oct 23;124(17):2725-9. doi: 10.1182/blood-2014-02-559468. Epub 2014 Jul 25.


Identification of the niche and phenotype of the first human hematopoietic stem cells.

Ivanovs A, Rybtsov S, Anderson RA, Turner ML, Medvinsky A.

Stem Cell Reports. 2014 Mar 27;2(4):449-56. doi: 10.1016/j.stemcr.2014.02.004. eCollection 2014 Apr 8.


Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs.

Gordon-Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky A.

Blood. 2013 Oct 3;122(14):2338-45. doi: 10.1182/blood-2012-12-470971. Epub 2013 Jul 17.


Role of host cell traversal by the malaria sporozoite during liver infection.

Tavares J, Formaglio P, Thiberge S, Mordelet E, Van Rooijen N, Medvinsky A, Ménard R, Amino R.

J Exp Med. 2013 May 6;210(5):905-15. doi: 10.1084/jem.20121130. Epub 2013 Apr 22.


Postmenstrual gestational age should be used with care in studies of early human hematopoietic development.

Ivanovs A, Rybtsov S, Anderson RA, Turner ML, Medvinsky A.

Blood. 2013 Apr 11;121(15):3051-2. doi: 10.1182/blood-2013-01-475673. No abstract available.


Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.

Voronov D, Gromova A, Liu D, Zoukhri D, Medvinsky A, Meech R, Makarenkova HP.

Invest Ophthalmol Vis Sci. 2013 May 1;54(5):3115-25. doi: 10.1167/iovs.13-11791.


Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis.

Fitch SR, Kimber GM, Wilson NK, Parker A, Mirshekar-Syahkal B, Göttgens B, Medvinsky A, Dzierzak E, Ottersbach K.

Cell Stem Cell. 2012 Oct 5;11(4):554-66. doi: 10.1016/j.stem.2012.07.002.


Imaging sporozoite cell traversal in the liver of mice.

Tavares J, Formaglio P, Medvinsky A, Ménard R, Amino R.

Methods Mol Biol. 2013;923:401-10.


Endothelio-hematopoietic relationship: getting closer to the beginnings.

Gordon-Keylock S, Medvinsky A.

BMC Biol. 2011 Dec 28;9:88. doi: 10.1186/1741-7007-9-88.


Highly potent human hematopoietic stem cells first emerge in the intraembryonic aorta-gonad-mesonephros region.

Ivanovs A, Rybtsov S, Welch L, Anderson RA, Turner ML, Medvinsky A.

J Exp Med. 2011 Nov 21;208(12):2417-27. doi: 10.1084/jem.20111688. Epub 2011 Oct 31.


Hierarchical organization and early hematopoietic specification of the developing HSC lineage in the AGM region.

Rybtsov S, Sobiesiak M, Taoudi S, Souilhol C, Senserrich J, Liakhovitskaia A, Ivanovs A, Frampton J, Zhao S, Medvinsky A.

J Exp Med. 2011 Jun 6;208(6):1305-15. doi: 10.1084/jem.20102419. Epub 2011 May 30.


Embryonic origin of the adult hematopoietic system: advances and questions.

Medvinsky A, Rybtsov S, Taoudi S.

Development. 2011 Mar;138(6):1017-31. doi: 10.1242/dev.040998. Review.


Hoxb4-YFP reporter mouse model: a novel tool for tracking HSC development and studying the role of Hoxb4 in hematopoiesis.

Hills D, Gribi R, Ure J, Buza-Vidas N, Luc S, Jacobsen SE, Medvinsky A.

Blood. 2011 Mar 31;117(13):3521-8. doi: 10.1182/blood-2009-12-253989. Epub 2011 Jan 28.


Endothelial cells dynamically compete for the tip cell position during angiogenic sprouting.

Jakobsson L, Franco CA, Bentley K, Collins RT, Ponsioen B, Aspalter IM, Rosewell I, Busse M, Thurston G, Medvinsky A, Schulte-Merker S, Gerhardt H.

Nat Cell Biol. 2010 Oct;12(10):943-53. doi: 10.1038/ncb2103. Epub 2010 Sep 26.

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