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Items: 1 to 20 of 72


Developing HSCs become Notch independent by the end of maturation in the AGM region.

Souilhol C, Lendinez JG, Rybtsov S, Murphy F, Wilson H, Hills D, Batsivari A, Binagui-Casas A, McGarvey AC, MacDonald HR, Kageyama R, Siebel C, Zhao S, Medvinsky A.

Blood. 2016 Jul 15. pii: blood-2016-03-708164. [Epub ahead of print]


Concealed expansion of immature precursors underpins acute burst of adult HSC activity in foetal liver.

Rybtsov S, Ivanovs A, Zhao S, Medvinsky A.

Development. 2016 Apr 15;143(8):1284-9. doi: 10.1242/dev.131193.


Inductive interactions mediated by interplay of asymmetric signalling underlie development of adult haematopoietic stem cells.

Souilhol C, Gonneau C, Lendinez JG, Batsivari A, Rybtsov S, Wilson H, Morgado-Palacin L, Hills D, Taoudi S, Antonchuk J, Zhao S, Medvinsky A.

Nat Commun. 2016 Mar 8;7:10784. doi: 10.1038/ncomms10784.


Deletion of Pten in CD45-expressing cells leads to development of T-cell lymphoblastic lymphoma but not myeloid malignancies.

Mirantes C, Dosil MA, Hills D, Yang J, Eritja N, Santacana M, Gatius S, Vilardell F, Medvinsky A, Matias-Guiu X, Dolcet X.

Blood. 2016 Apr 14;127(15):1907-11. doi: 10.1182/blood-2015-09-669036. Epub 2016 Jan 14.


Intrinsic factors and the embryonic environment influence the formation of extragonadal teratomas during gestation.

Economou C, Tsakiridis A, Wymeersch FJ, Gordon-Keylock S, Dewhurst RE, Fisher D, Medvinsky A, Smith AJ, Wilson V.

BMC Dev Biol. 2015 Oct 9;15:35. doi: 10.1186/s12861-015-0084-7.


[Divergence of Chlorophyll Dynamics in the Naroch Lakes].

Adamovich BV, Kovalevskaya RZ, Radchikova NP, Zhukova TV, Mikheyeva TM, Medvinsky AB, Nuriyeva NI, Rusakov AV.

Biofizika. 2015 Jul-Aug;60(4):769-76. Russian.


Identification of the genes regulated by Wnt-4, a critical signal for commitment of the ovary.

Naillat F, Yan W, Karjalainen R, Liakhovitskaia A, Samoylenko A, Xu Q, Sun Z, Shen B, Medvinsky A, Quaggin S, Vainio SJ.

Exp Cell Res. 2015 Mar 15;332(2):163-78. doi: 10.1016/j.yexcr.2015.01.010. Epub 2015 Jan 30.


In search of human hematopoietic stem cell identity.

Ivanovs A, Medvinsky A.

Cell Stem Cell. 2015 Jan 8;16(1):5-6. doi: 10.1016/j.stem.2014.12.010.


On human development: lessons from stem cell systems.

Medvinsky A, Livesey FJ.

Development. 2015 Jan 1;142(1):17-20. doi: 10.1242/dev.114868.


Directed differentiation of embryonic stem cells using a bead-based combinatorial screening method.

Tarunina M, Hernandez D, Johnson CJ, Rybtsov S, Ramathas V, Jeyakumar M, Watson T, Hook L, Medvinsky A, Mason C, Choo Y.

PLoS One. 2014 Sep 24;9(9):e104301. doi: 10.1371/journal.pone.0104301. eCollection 2014.


Tracing the origin of the HSC hierarchy reveals an SCF-dependent, IL-3-independent CD43(-) embryonic precursor.

Rybtsov S, Batsivari A, Bilotkach K, Paruzina D, Senserrich J, Nerushev O, Medvinsky A.

Stem Cell Reports. 2014 Sep 9;3(3):489-501. doi: 10.1016/j.stemcr.2014.07.009. Epub 2014 Aug 28.


Runx1 is required for progression of CD41+ embryonic precursors into HSCs but not prior to this.

Liakhovitskaia A, Rybtsov S, Smith T, Batsivari A, Rybtsova N, Rode C, de Bruijn M, Buchholz F, Gordon-Keylock S, Zhao S, Medvinsky A.

Development. 2014 Sep;141(17):3319-23. doi: 10.1242/dev.110841.


A lineage of diploid platelet-forming cells precedes polyploid megakaryocyte formation in the mouse embryo.

Potts KS, Sargeant TJ, Markham JF, Shi W, Biben C, Josefsson EC, Whitehead LW, Rogers KL, Liakhovitskaia A, Smyth GK, Kile BT, Medvinsky A, Alexander WS, Hilton DJ, Taoudi S.

Blood. 2014 Oct 23;124(17):2725-9. doi: 10.1182/blood-2014-02-559468. Epub 2014 Jul 25.


Identification of the niche and phenotype of the first human hematopoietic stem cells.

Ivanovs A, Rybtsov S, Anderson RA, Turner ML, Medvinsky A.

Stem Cell Reports. 2014 Mar 27;2(4):449-56. doi: 10.1016/j.stemcr.2014.02.004. eCollection 2014 Apr 8.


Mouse extraembryonic arterial vessels harbor precursors capable of maturing into definitive HSCs.

Gordon-Keylock S, Sobiesiak M, Rybtsov S, Moore K, Medvinsky A.

Blood. 2013 Oct 3;122(14):2338-45. doi: 10.1182/blood-2012-12-470971. Epub 2013 Jul 17.


Role of host cell traversal by the malaria sporozoite during liver infection.

Tavares J, Formaglio P, Thiberge S, Mordelet E, Van Rooijen N, Medvinsky A, Ménard R, Amino R.

J Exp Med. 2013 May 6;210(5):905-15. doi: 10.1084/jem.20121130. Epub 2013 Apr 22.


Postmenstrual gestational age should be used with care in studies of early human hematopoietic development.

Ivanovs A, Rybtsov S, Anderson RA, Turner ML, Medvinsky A.

Blood. 2013 Apr 11;121(15):3051-2. doi: 10.1182/blood-2013-01-475673. No abstract available.


Transcription factors Runx1 to 3 are expressed in the lacrimal gland epithelium and are involved in regulation of gland morphogenesis and regeneration.

Voronov D, Gromova A, Liu D, Zoukhri D, Medvinsky A, Meech R, Makarenkova HP.

Invest Ophthalmol Vis Sci. 2013 May 1;54(5):3115-25. doi: 10.1167/iovs.13-11791.


Signaling from the sympathetic nervous system regulates hematopoietic stem cell emergence during embryogenesis.

Fitch SR, Kimber GM, Wilson NK, Parker A, Mirshekar-Syahkal B, Göttgens B, Medvinsky A, Dzierzak E, Ottersbach K.

Cell Stem Cell. 2012 Oct 5;11(4):554-66. doi: 10.1016/j.stem.2012.07.002.


Imaging sporozoite cell traversal in the liver of mice.

Tavares J, Formaglio P, Medvinsky A, Ménard R, Amino R.

Methods Mol Biol. 2013;923:401-10.

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