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Results: 1 to 20 of 261

1.

Ankylosing spondylitis patients display altered dendritic cell and T cell populations that implicate pathogenic roles for the IL-23 cytokine axis and intestinal inflammation.

Wright PB, McEntegart A, McCarey D, McInnes IB, Siebert S, Milling SW.

Rheumatology (Oxford). 2015 Aug 28. pii: kev245. [Epub ahead of print]

2.

Spinal cord oligodendrocyte-derived alarmin IL-33 mediates neuropathic pain.

Zarpelon AC, Rodrigues FC, Lopes AH, Souza GR, Carvalho TT, Pinto LG, Xu D, Ferreira SH, Alves-Filho JC, McInnes IB, Ryffel B, Quesniaux VF, Reverchon F, Mortaud S, Menuet A, Liew FY, Cunha FQ, Cunha TM, Verri WA Jr.

FASEB J. 2015 Aug 26. pii: fj.14-267146. [Epub ahead of print]

PMID:
26310268
3.

MICL controls inflammation in rheumatoid arthritis.

Redelinghuys P, Whitehead L, Augello A, Drummond RA, Levesque JM, Vautier S, Reid DM, Kerscher B, Taylor JA, Nigrovic PA, Wright J, Murray GI, Willment JA, Hocking LJ, Fernandes MJ, De Bari C, Mcinnes IB, Brown GD.

Ann Rheum Dis. 2015 Aug 14. pii: annrheumdis-2014-206644. doi: 10.1136/annrheumdis-2014-206644. [Epub ahead of print]

4.

Circulating tumour necrosis factor is highly correlated with brainstem serotonin transporter availability in humans.

Krishnadas R, Nicol A, Sassarini J, Puri N, Burden AD, Leman J, Combet E, Pimlott S, Hadley D, McInnes IB, Cavanagh J.

Brain Behav Immun. 2015 Aug 6. pii: S0889-1591(15)00429-8. doi: 10.1016/j.bbi.2015.08.005. [Epub ahead of print]

PMID:
26255693
5.

Combined Free Light Chains Are Novel Predictors of Prognosis in Heart Failure.

Jackson CE, Haig C, Welsh P, Dalzell JR, Tsorlalis IK, McConnachie A, Preiss D, McInnes IB, Sattar N, Petrie MC, Gardner RS, McMurray JJ.

JACC Heart Fail. 2015 Aug;3(8):618-25. doi: 10.1016/j.jchf.2015.03.014.

PMID:
26251088
6.

Long-term effects of secukinumab on MRI findings in relation to clinical efficacy in subjects with active ankylosing spondylitis: an observational study.

Baraliakos X, Borah B, Braun J, Baeten D, Laurent D, Sieper J, Emery P, McInnes IB, van Laar JM, Wordsworth P, Wollenhaupt J, Kellner H, Colin L, Vandenhende F, Radford K, Hueber W.

Ann Rheum Dis. 2015 Aug 6. pii: annrheumdis-2015-207544. doi: 10.1136/annrheumdis-2015-207544. [Epub ahead of print]

PMID:
26248638
7.

Rheumatoid arthritis: Debunking the obesity-mortality paradox in RA.

Sattar N, McInnes IB.

Nat Rev Rheumatol. 2015 Aug;11(8):445-6. doi: 10.1038/nrrheum.2015.93. Epub 2015 Jul 7. No abstract available.

PMID:
26150124
8.

Secukinumab, a human anti-interleukin-17A monoclonal antibody, in patients with psoriatic arthritis (FUTURE 2): a randomised, double-blind, placebo-controlled, phase 3 trial.

McInnes IB, Mease PJ, Kirkham B, Kavanaugh A, Ritchlin CT, Rahman P, van der Heijde D, Landewé R, Conaghan PG, Gottlieb AB, Richards H, Pricop L, Ligozio G, Patekar M, Mpofu S; FUTURE 2 Study Group.

Lancet. 2015 Jun 26. pii: S0140-6736(15)61134-5. doi: 10.1016/S0140-6736(15)61134-5. [Epub ahead of print]

PMID:
26135703
9.

Maintenance of clinical efficacy and radiographic benefit through 2 years of ustekinumab therapy in patients with active psoriatic arthritis: Results from the PSUMMIT 1 trial.

Kavanaugh A, Puig L, Gottlieb AB, Ritchlin C, Li S, Wang Y, Mendelsohn AM, Song M, Zhu Y, Rahman P, McInnes IB; PSUMMIT I Study Group.

Arthritis Care Res (Hoboken). 2015 Jun 19. doi: 10.1002/acr.22645. [Epub ahead of print]

PMID:
26097039
10.

Artery Tertiary Lymphoid Organs Control Aorta Immunity and Protect against Atherosclerosis via Vascular Smooth Muscle Cell Lymphotoxin β Receptors.

Hu D, Mohanta SK, Yin C, Peng L, Ma Z, Srikakulapu P, Grassia G, MacRitchie N, Dever G, Gordon P, Burton FL, Ialenti A, Sabir SR, McInnes IB, Brewer JM, Garside P, Weber C, Lehmann T, Teupser D, Habenicht L, Beer M, Grabner R, Maffia P, Weih F, Habenicht AJ.

Immunity. 2015 Jun 16;42(6):1100-15. doi: 10.1016/j.immuni.2015.05.015.

PMID:
26084025
11.

MicroRNA29a regulates IL-33-mediated tissue remodelling in tendon disease.

Millar NL, Gilchrist DS, Akbar M, Reilly JH, Kerr SC, Campbell AL, Murrell GA, Liew FY, Kurowska-Stolarska M, McInnes IB.

Nat Commun. 2015 Apr 10;6:6774. doi: 10.1038/ncomms7774.

12.

Cellular imaging in rheumatic diseases.

Benson RA, McInnes IB, Brewer JM, Garside P.

Nat Rev Rheumatol. 2015 Jun;11(6):357-67. doi: 10.1038/nrrheum.2015.34. Epub 2015 Mar 24. Review.

PMID:
25800215
13.

Patients with psoriatic arthritis who achieve minimal disease activity in response to golimumab therapy demonstrate less radiographic progression: Results through 5 years of the randomized, placebo-controlled, GO-REVEAL study.

Kavanaugh A, van der Heijde D, Beutler A, Gladman D, Mease P, Krueger GG, McInnes IB, Helliwell P, Coates LC, Xu S.

Arthritis Care Res (Hoboken). 2015 Mar 16. doi: 10.1002/acr.22576. [Epub ahead of print]

PMID:
25779603
14.

Elevated interleukin-10: a new cause of dyslipidemia leading to severe HDL deficiency.

Moraitis AG, Freeman LA, Shamburek RD, Wesley R, Wilson W, Grant CM, Price S, Demosky S, Thacker SG, Zarzour A, Hornung RL, Pucino F, Csako G, Yarboro C, McInnes IB, Kuroiwa T, Boumpas D, Rao VK, Illei GG, Remaley AT.

J Clin Lipidol. 2015 Jan-Feb;9(1):81-90. doi: 10.1016/j.jacl.2014.09.014. Epub 2014 Oct 5.

PMID:
25670364
15.

The JAK-STAT pathway: impact on human disease and therapeutic intervention.

O'Shea JJ, Schwartz DM, Villarino AV, Gadina M, McInnes IB, Laurence A.

Annu Rev Med. 2015;66:311-28. doi: 10.1146/annurev-med-051113-024537.

PMID:
25587654
16.

Psoriatic arthritis - expanding options, exciting times?

McInnes IB, Siebert S.

Acta Reumatol Port. 2014 Oct-Dec;39(4):294-5. No abstract available.

17.

Small-molecule therapeutics in rheumatoid arthritis: scientific rationale, efficacy and safety.

Meier FM, McInnes IB.

Best Pract Res Clin Rheumatol. 2014 Aug;28(4):605-24. doi: 10.1016/j.berh.2014.10.017. Epub 2014 Nov 21. Review.

PMID:
25481553
18.

Potential mechanisms leading to the abnormal lipid profile in patients with rheumatoid arthritis versus healthy volunteers and reversal by tofacitinib.

Charles-Schoeman C, Fleischmann R, Davignon J, Schwartz H, Turner SM, Beysen C, Milad M, Hellerstein MK, Luo Z, Kaplan IV, Riese R, Zuckerman A, McInnes IB.

Arthritis Rheumatol. 2015 Mar;67(3):616-25. doi: 10.1002/art.38974.

PMID:
25470338
19.

Psoriasis, psoriatic arthritis and cardiovascular risk: are we closer to a clinical recommendation?

Kristensen SL, McInnes IB, Sattar N.

Ann Rheum Dis. 2015 Feb;74(2):321-2. doi: 10.1136/annrheumdis-2014-206617. Epub 2014 Nov 26. No abstract available.

PMID:
25429028
20.

The atypical chemokine receptor ACKR2 suppresses Th17 responses to protein autoantigens.

Hansell CA, MacLellan LM, Oldham RS, Doonan J, Chapple KJ, Anderson EJ, Linington C, McInnes IB, Nibbs RJ, Goodyear CS.

Immunol Cell Biol. 2015 Feb;93(2):167-76. doi: 10.1038/icb.2014.90. Epub 2014 Oct 28.

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