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Results: 9

1.

Effects of chemical manipulation of mitotic arrest and slippage on cancer cell survival and proliferation.

Riffell JL, Zimmerman C, Khong A, McHardy LM, Roberge M.

Cell Cycle. 2009 Sep 15;8(18):3025-38. Epub 2009 Sep 25.

PMID:
19713760
[PubMed - indexed for MEDLINE]
Free Article
2.

Combining chemical genomics screens in yeast to reveal spectrum of effects of chemical inhibition of sphingolipid biosynthesis.

Kemmer D, McHardy LM, Hoon S, Rebérioux D, Giaever G, Nislow C, Roskelley CD, Roberge M.

BMC Microbiol. 2009 Jan 14;9:9. doi: 10.1186/1471-2180-9-9.

PMID:
19144191
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Abrogation of ionizing radiation-induced G2 checkpoint and inhibition of nuclear export by Cryptocarya pyrones.

Sturgeon CM, Cinel B, Díaz-Marrero AR, McHardy LM, Ngo M, Andersen RJ, Roberge M.

Cancer Chemother Pharmacol. 2008 Mar;61(3):407-13. Epub 2007 Apr 18.

PMID:
17440726
[PubMed - indexed for MEDLINE]
4.

Strongylophorine-26, a Rho-dependent inhibitor of tumor cell invasion that reduces actin stress fibers and induces nonpolarized lamellipodial extensions.

McHardy LM, Warabi K, Andersen RJ, Roskelley CD, Roberge M.

Mol Cancer Ther. 2005 May;4(5):772-8.

PMID:
15897241
[PubMed - indexed for MEDLINE]
Free Article
5.

Strongylophorine-26, a new meroditerpenoid isolated from the marine sponge Petrosia (Strongylophora) corticata that exhibits anti-invasion activity.

Warabi K, McHardy LM, Matainaho L, Van Soest R, Roskelley CD, Roberge M, Andersen RJ.

J Nat Prod. 2004 Aug;67(8):1387-9.

PMID:
15332859
[PubMed - indexed for MEDLINE]
6.

The tumor invasion inhibitor dihydromotuporamine C activates RHO, remodels stress fibers and focal adhesions, and stimulates sodium-proton exchange.

McHardy LM, Sinotte R, Troussard A, Sheldon C, Church J, Williams DE, Andersen RJ, Dedhar S, Roberge M, Roskelley CD.

Cancer Res. 2004 Feb 15;64(4):1468-74.

PMID:
14973060
[PubMed - indexed for MEDLINE]
Free Article
7.

Motuporamines, anti-invasion and anti-angiogenic alkaloids from the marine sponge Xestospongia exigua (Kirkpatrick): isolation, structure elucidation, analogue synthesis, and conformational analysis.

Williams DE, Craig KS, Patrick B, McHardy LM, van Soest R, Roberge M, Andersen RJ.

J Org Chem. 2002 Jan 11;67(1):245-58.

PMID:
11777468
[PubMed - indexed for MEDLINE]
8.

Inhibition of tumor cell invasion and angiogenesis by motuporamines.

Roskelley CD, Williams DE, McHardy LM, Leong KG, Troussard A, Karsan A, Andersen RJ, Dedhar S, Roberge M.

Cancer Res. 2001 Sep 15;61(18):6788-94.

PMID:
11559552
[PubMed - indexed for MEDLINE]
Free Article
9.

Synthetic transformations of eleutherobin reveal new features of its microtubule-stabilizing pharmacophore.

Britton R, de Silva ED, Bigg CM, McHardy LM, Roberge M, Andersen RJ.

J Am Chem Soc. 2001 Sep 5;123(35):8632-3. No abstract available.

PMID:
11525686
[PubMed - indexed for MEDLINE]
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