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Results: 1 to 20 of 312

1.

Using Markov State Models to Develop a Mechanistic Understanding of Protein Kinase A-RIα Activation in Response to cAMP Binding.

Boras BW, Kornev A, Taylor SS, McCulloch AD.

J Biol Chem. 2014 Sep 8. pii: jbc.M114.568907. [Epub ahead of print]

PMID:
25202018
[PubMed - as supplied by publisher]
Free Article
2.

PKA Phosphorylation of Cardiac Troponin I Modulates Activation and Relaxation Kinetics of Ventricular Myofibrils.

Rao V, Cheng Y, Lindert S, Wang D, Oxenford L, McCulloch AD, McCammon JA, Regnier M.

Biophys J. 2014 Sep 2;107(5):1196-204. doi: 10.1016/j.bpj.2014.07.027.

PMID:
25185555
[PubMed - in process]
3.

Patient-specific modeling of ventricular activation pattern using surface ECG-derived vectorcardiogram in bundle branch block.

Villongco CT, Krummen DE, Stark P, Omens JH, McCulloch AD.

Prog Biophys Mol Biol. 2014 Aug 7. pii: S0079-6107(14)00068-6. doi: 10.1016/j.pbiomolbio.2014.06.011. [Epub ahead of print]

PMID:
25110279
[PubMed - as supplied by publisher]
4.

Detailed observation of space-charge dynamics using ultracold ion bunches.

Murphy D, Speirs RW, Sheludko DV, Putkunz CT, McCulloch AJ, Sparkes BM, Scholten RE.

Nat Commun. 2014 Jul 17;5:4489. doi: 10.1038/ncomms5489.

PMID:
25030321
[PubMed - in process]
5.

Toward a hierarchy of mechanisms in CaMKII-mediated arrhythmia.

Vincent KP, McCulloch AD, Edwards AG.

Front Pharmacol. 2014 May 16;5:110. doi: 10.3389/fphar.2014.00110. eCollection 2014. Review.

PMID:
24994983
[PubMed]
Free PMC Article
6.

Timing and magnitude of systolic stretch affect myofilament activation and mechanical work.

Tangney JR, Campbell SG, McCulloch AD, Omens JH.

Am J Physiol Heart Circ Physiol. 2014 Aug 1;307(3):H353-60. doi: 10.1152/ajpheart.00233.2014. Epub 2014 May 30.

PMID:
24878774
[PubMed - in process]
7.

High-Coherence Electron and Ion Bunches From Laser-Cooled Atoms.

Sparkes BM, Thompson DJ, McCulloch AJ, Murphy D, Speirs RW, Torrance JS, Scholten RE.

Microsc Microanal. 2014 Apr 24:1-7. [Epub ahead of print]

PMID:
24758916
[PubMed - as supplied by publisher]
8.

Calcium and IP3 dynamics in cardiac myocytes: experimental and computational perspectives and approaches.

Hohendanner F, McCulloch AD, Blatter LA, Michailova AP.

Front Pharmacol. 2014 Mar 6;5:35. doi: 10.3389/fphar.2014.00035. eCollection 2014. Review.

PMID:
24639654
[PubMed]
Free PMC Article
9.

MAAMD: a workflow to standardize meta-analyses and comparison of affymetrix microarray data.

Gan Z, Wang J, Salomonis N, Stowe JC, Haddad GG, McCulloch AD, Altintas I, Zambon AC.

BMC Bioinformatics. 2014 Mar 12;15:69. doi: 10.1186/1471-2105-15-69.

PMID:
24621103
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Targeted ablation of nesprin 1 and nesprin 2 from murine myocardium results in cardiomyopathy, altered nuclear morphology and inhibition of the biomechanical gene response.

Banerjee I, Zhang J, Moore-Morris T, Pfeiffer E, Buchholz KS, Liu A, Ouyang K, Stroud MJ, Gerace L, Evans SM, McCulloch A, Chen J.

PLoS Genet. 2014 Feb 20;10(2):e1004114. doi: 10.1371/journal.pgen.1004114. eCollection 2014 Feb.

PMID:
24586179
[PubMed - in process]
Free PMC Article
11.

Computational modeling of subcellular transport and signaling.

Hake J, Kekenes-Huskey PM, McCulloch AD.

Curr Opin Struct Biol. 2014 Apr;25:92-7. doi: 10.1016/j.sbi.2014.01.006. Epub 2014 Feb 7.

PMID:
24509246
[PubMed - in process]
12.

Analyses of hypomethylated oil palm gene space.

Low ET, Rosli R, Jayanthi N, Mohd-Amin AH, Azizi N, Chan KL, Maqbool NJ, Maclean P, Brauning R, McCulloch A, Moraga R, Ong-Abdullah M, Singh R.

PLoS One. 2014 Jan 30;9(1):e86728. doi: 10.1371/journal.pone.0086728. eCollection 2014.

PMID:
24497974
[PubMed - in process]
Free PMC Article
13.

A novel computational model of mouse myocyte electrophysiology to assess the synergy between Na+ loading and CaMKII.

Morotti S, Edwards AG, McCulloch AD, Bers DM, Grandi E.

J Physiol. 2014 Mar 15;592(Pt 6):1181-97. doi: 10.1113/jphysiol.2013.266676. Epub 2014 Jan 13.

PMID:
24421356
[PubMed - in process]
14.

Multi-core CPU or GPU-accelerated Multiscale Modeling for Biomolecular Complexes.

Liao T, Zhang Y, Kekenes-Huskey PM, Cheng Y, Michailova A, McCulloch AD, Holst M, McCammon JA.

Mol Based Math Biol. 2013 Jul;1. doi: 10.2478/mlbmb-2013-0009.

PMID:
24352481
[PubMed]
Free PMC Article
15.

Biomechanics of cardiac electromechanical coupling and mechanoelectric feedback.

Pfeiffer ER, Tangney JR, Omens JH, McCulloch AD.

J Biomech Eng. 2014 Feb;136(2):021007. doi: 10.1115/1.4026221.

PMID:
24337452
[PubMed - in process]
16.

Sensitivity of rabbit ventricular action potential and Ca²⁺ dynamics to small variations in membrane currents and ion diffusion coefficients.

Lo YH, Peachey T, Abramson D, McCulloch A, Michailova A.

Biomed Res Int. 2013;2013:565431. doi: 10.1155/2013/565431. Epub 2013 Oct 7.

PMID:
24222910
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Molecular and subcellular-scale modeling of nucleotide diffusion in the cardiac myofilament lattice.

Kekenes-Huskey PM, Liao T, Gillette AK, Hake JE, Zhang Y, Michailova AP, McCulloch AD, McCammon JA.

Biophys J. 2013 Nov 5;105(9):2130-40. doi: 10.1016/j.bpj.2013.09.020.

PMID:
24209858
[PubMed - indexed for MEDLINE]
Free Article
18.

Connexin defects underlie arrhythmogenic right ventricular cardiomyopathy in a novel mouse model.

Lyon RC, Mezzano V, Wright AT, Pfeiffer E, Chuang J, Banares K, Castaneda A, Ouyang K, Cui L, Contu R, Gu Y, Evans SM, Omens JH, Peterson KL, McCulloch AD, Sheikh F.

Hum Mol Genet. 2014 Mar 1;23(5):1134-50. doi: 10.1093/hmg/ddt508. Epub 2013 Oct 9.

PMID:
24108106
[PubMed - in process]
19.

The promise of CaMKII inhibition for heart disease: preventing heart failure and arrhythmias.

Westenbrink BD, Edwards AG, McCulloch AD, Brown JH.

Expert Opin Ther Targets. 2013 Aug;17(8):889-903. doi: 10.1517/14728222.2013.809064. Epub 2013 Jun 24. Review.

PMID:
23789646
[PubMed - indexed for MEDLINE]
20.

Patient-Specific Models of Cardiac Biomechanics.

Krishnamurthy A, Villongco CT, Chuang J, Frank LR, Nigam V, Belezzuoli E, Stark P, Krummen DE, Narayan S, Omens JH, McCulloch AD, Kerckhoffs RC.

J Comput Phys. 2013 Jul 1;244:4-21.

PMID:
23729839
[PubMed]
Free PMC Article

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