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Items: 1 to 20 of 177

1.

Characterization of the Plasmodium falciparum and P. berghei glycerol 3-phosphate acyltransferase involved in FASII fatty acid utilization in the malaria parasite apicoplast.

Shears MJ, MacRae JI, Mollard V, Goodman CD, Sturm A, Orchard LM, Llinás M, McConville MJ, Botté CY, McFadden GI.

Cell Microbiol. 2016 Jun 20. doi: 10.1111/cmi.12633. [Epub ahead of print]

PMID:
27324409
2.

Reversing diet-induced metabolic dysregulation by diet switching leads to altered hepatic de novo lipogenesis and glycerolipid synthesis.

Kowalski GM, Hamley S, Selathurai A, Kloehn J, De Souza DP, O'Callaghan S, Nijagal B, Tull DL, McConville MJ, Bruce CR.

Sci Rep. 2016 Jun 7;6:27541. doi: 10.1038/srep27541.

3.

Metabolic Crosstalk between Leishmania and the Macrophage Host.

McConville MJ.

Trends Parasitol. 2016 May 24. pii: S1471-4922(16)30051-4. doi: 10.1016/j.pt.2016.05.005. [Epub ahead of print]

PMID:
27234812
4.

Using metabolomics to dissect host-parasite interactions.

Kloehn J, Blume M, Cobbold SA, Saunders EC, Dagley MJ, McConville MJ.

Curr Opin Microbiol. 2016 May 17;32:59-65. doi: 10.1016/j.mib.2016.04.019. [Epub ahead of print] Review.

PMID:
27200489
5.

Lipidomic Profiling of Adipose Tissue Reveals an Inflammatory Signature in Cancer-Related and Primary Lymphedema.

Sedger LM, Tull DL, McConville MJ, De Souza DP, Rupasinghe TW, Williams SJ, Dayalan S, Lanzer D, Mackie H, Lam TC, Boyages J.

PLoS One. 2016 May 16;11(5):e0154650. doi: 10.1371/journal.pone.0154650. eCollection 2016.

6.

Overexpression of Striated Muscle Activator of Rho Signaling (STARS) Increases C2C12 Skeletal Muscle Cell Differentiation.

Wallace MA, Della Gatta PA, Ahmad Mir B, Kowalski GM, Kloehn J, McConville MJ, Russell AP, Lamon S.

Front Physiol. 2016 Feb 8;7:7. doi: 10.3389/fphys.2016.00007. eCollection 2016.

7.

Legionella pneumophila S1P-lyase targets host sphingolipid metabolism and restrains autophagy.

Rolando M, Escoll P, Nora T, Botti J, Boitez V, Bedia C, Daniels C, Abraham G, Stogios PJ, Skarina T, Christophe C, Dervins-Ravault D, Cazalet C, Hilbi H, Rupasinghe TW, Tull D, McConville MJ, Ong SY, Hartland EL, Codogno P, Levade T, Naderer T, Savchenko A, Buchrieser C.

Proc Natl Acad Sci U S A. 2016 Feb 16;113(7):1901-6. doi: 10.1073/pnas.1522067113. Epub 2016 Feb 1.

PMID:
26831115
8.

Regulation of Starch Stores by a Ca(2+)-Dependent Protein Kinase Is Essential for Viable Cyst Development in Toxoplasma gondii.

Uboldi AD, McCoy JM, Blume M, Gerlic M, Ferguson DJ, Dagley LF, Beahan CT, Stapleton DI, Gooley PR, Bacic A, Masters SL, Webb AI, McConville MJ, Tonkin CJ.

Cell Host Microbe. 2015 Dec 9;18(6):670-81. doi: 10.1016/j.chom.2015.11.004.

PMID:
26651943
9.

Time-Dependent Transcriptional Changes in Axenic Giardia duodenalis Trophozoites.

Ansell BR, McConville MJ, Baker L, Korhonen PK, Young ND, Hall RS, Rojas CA, Svärd SG, Gasser RB, Jex AR.

PLoS Negl Trop Dis. 2015 Dec 4;9(12):e0004261. doi: 10.1371/journal.pntd.0004261. eCollection 2015 Dec.

10.

Leishmania carbon metabolism in the macrophage phagolysosome- feast or famine?

McConville MJ, Saunders EC, Kloehn J, Dagley MJ.

F1000Res. 2015 Oct 1;4(F1000 Faculty Rev):938. doi: 10.12688/f1000research.6724.1. eCollection 2015. Review.

11.

Intracellular Survival of Leishmania major Depends on Uptake and Degradation of Extracellular Matrix Glycosaminoglycans by Macrophages.

Naderer T, Heng J, Saunders EC, Kloehn J, Rupasinghe TW, Brown TJ, McConville MJ.

PLoS Pathog. 2015 Sep 3;11(9):e1005136. doi: 10.1371/journal.ppat.1005136. eCollection 2015 Sep.

12.

A Toxoplasma gondii Gluconeogenic Enzyme Contributes to Robust Central Carbon Metabolism and Is Essential for Replication and Virulence.

Blume M, Nitzsche R, Sternberg U, Gerlic M, Masters SL, Gupta N, McConville MJ.

Cell Host Microbe. 2015 Aug 12;18(2):210-20. doi: 10.1016/j.chom.2015.07.008.

PMID:
26269956
13.

High-content assay for measuring intracellular growth of Leishmania in human macrophages.

Dagley MJ, Saunders EC, Simpson KJ, McConville MJ.

Assay Drug Dev Technol. 2015 Sep;13(7):389-401. doi: 10.1089/adt.2015.652. Epub 2015 Aug 6.

PMID:
26247370
14.

Plasmodium falciparum glucose-6-phosphate dehydrogenase 6-phosphogluconolactonase is a potential drug target.

Allen SM, Lim EE, Jortzik E, Preuss J, Chua HH, MacRae JI, Rahlfs S, Haeussler K, Downton MT, McConville MJ, Becker K, Ralph SA.

FEBS J. 2015 Oct;282(19):3808-23. doi: 10.1111/febs.13380. Epub 2015 Aug 17.

PMID:
26198663
15.

Metabolic Dysregulation Induced in Plasmodium falciparum by Dihydroartemisinin and Other Front-Line Antimalarial Drugs.

Cobbold SA, Chua HH, Nijagal B, Creek DJ, Ralph SA, McConville MJ.

J Infect Dis. 2016 Jan 15;213(2):276-86. doi: 10.1093/infdis/jiv372. Epub 2015 Jul 6.

PMID:
26150544
16.

Evidence that asthma is a developmental origin disease influenced by maternal diet and bacterial metabolites.

Thorburn AN, McKenzie CI, Shen S, Stanley D, Macia L, Mason LJ, Roberts LK, Wong CH, Shim R, Robert R, Chevalier N, Tan JK, Mariño E, Moore RJ, Wong L, McConville MJ, Tull DL, Wood LG, Murphy VE, Mattes J, Gibson PG, Mackay CR.

Nat Commun. 2015 Jun 23;6:7320. doi: 10.1038/ncomms8320.

PMID:
26102221
17.

An Efficient Single Phase Method for the Extraction of Plasma Lipids.

Alshehry ZH, Barlow CK, Weir JM, Zhou Y, McConville MJ, Meikle PJ.

Metabolites. 2015 Jun 17;5(2):389-403. doi: 10.3390/metabo5020389.

18.

In vivo cardiac glucose metabolism in the high-fat fed mouse: Comparison of euglycemic-hyperinsulinemic clamp derived measures of glucose uptake with a dynamic metabolomic flux profiling approach.

Kowalski GM, De Souza DP, Risis S, Burch ML, Hamley S, Kloehn J, Selathurai A, Lee-Young RS, Tull D, O'Callaghan S, McConville MJ, Bruce CR.

Biochem Biophys Res Commun. 2015 Aug 7;463(4):818-24. doi: 10.1016/j.bbrc.2015.06.019. Epub 2015 Jun 15.

PMID:
26086096
19.

Host reticulocytes provide metabolic reservoirs that can be exploited by malaria parasites.

Srivastava A, Creek DJ, Evans KJ, De Souza D, Schofield L, Müller S, Barrett MP, McConville MJ, Waters AP.

PLoS Pathog. 2015 Jun 4;11(6):e1004882. doi: 10.1371/journal.ppat.1004882. eCollection 2015 Jun.

20.

Application of dynamic metabolomics to examine in vivo skeletal muscle glucose metabolism in the chronically high-fat fed mouse.

Kowalski GM, De Souza DP, Burch ML, Hamley S, Kloehn J, Selathurai A, Tull D, O'Callaghan S, McConville MJ, Bruce CR.

Biochem Biophys Res Commun. 2015 Jun 19;462(1):27-32. doi: 10.1016/j.bbrc.2015.04.096. Epub 2015 Apr 28.

PMID:
25930998
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