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Results: 1 to 20 of 230

1.

Discovery of 1-(3,3-Dimethylbutyl)-3-(2-fluoro-4-methyl-5-(7-methyl-2-(methylamino)pyrido[2,3-d]pyrimidin-6-yl)phenyl)urea (LY3009120) as a Pan-RAF Inhibitor with Minimal Paradoxical Activation and Activity against BRAF or RAS Mutant Tumor Cells.

Henry JR, Kaufman MD, Peng SB, Ahn YM, Caldwell TM, Vogeti L, Telikepalli H, Lu WP, Hood MM, Rutkoski TJ, Smith BD, Vogeti S, Miller D, Wise SC, Chun L, Zhang X, Zhang Y, Kays L, Hipskind PA, Wrobleski AD, Lobb KL, Clay JM, Cohen JD, Walgren JL, McCann D, Patel P, Clawson DK, Guo S, Manglicmot D, Groshong C, Logan C, Starling JJ, Flynn DL.

J Med Chem. 2015 May 12. [Epub ahead of print]

PMID:
25965804
2.

Trends in opioid analgesic abuse and mortality in the United States.

McCann DJ, Skolnick P.

N Engl J Med. 2015 Apr 16;372(16):1572-3. doi: 10.1056/NEJMc1501822#SA1. No abstract available.

PMID:
25875269
3.

Family Caregivers' Experiences of Caring for a Relative With Younger Onset Dementia: A Qualitative Systematic Review.

Cabote CJ, Bramble M, McCann D.

J Fam Nurs. 2015 Feb 27. pii: 1074840715573870. [Epub ahead of print]

PMID:
25724671
4.

Elite female athletes' ventilatory compensation to decreased inspired o2 during the wingate test.

Fallon S, Belcoe A, Shawcross C, May A, Monteverde C, McCann D.

Res Q Exerc Sport. 2015 Jun;86(2):182-9. doi: 10.1080/02701367.2014.983448. Epub 2014 Dec 24.

PMID:
25539476
5.

Sleep deprivation in parents caring for children with complex needs at home: a mixed methods systematic review.

McCann D, Bull R, Winzenberg T.

J Fam Nurs. 2015 Feb;21(1):86-118. doi: 10.1177/1074840714562026. Epub 2014 Dec 19.

PMID:
25527511
6.

Water and sediment quality, nutrient biochemistry and pollution loads in an urban freshwater lake: balancing human and ecological services.

Waltham NJ, Reichelt-Brushett A, McCann D, Eyre BD.

Environ Sci Process Impacts. 2014 Dec;16(12):2804-13. doi: 10.1039/c4em00243a.

PMID:
25384753
7.

Overcoming barriers to effective early parenting interventions for attention-deficit hyperactivity disorder (ADHD): parent and practitioner views.

Smith E, Koerting J, Latter S, Knowles MM, McCann DC, Thompson M, Sonuga-Barke EJ.

Child Care Health Dev. 2015 Jan;41(1):93-102. doi: 10.1111/cch.12146. Epub 2014 May 12.

8.

Study protocol for a randomized controlled trial comparing the efficacy of a specialist and a generic parenting programme for the treatment of preschool ADHD.

McCann DC, Thompson M, Daley D, Barton J, Laver-Bradbury C, Hutchings J, Coghill D, Stanton L, Maishman T, Dixon L, Caddy J, Chorozoglou M, Raftery J, Sonuga-Barke E.

Trials. 2014 Apr 25;15:142. doi: 10.1186/1745-6215-15-142.

9.

Characterization of LY2228820 dimesylate, a potent and selective inhibitor of p38 MAPK with antitumor activity.

Campbell RM, Anderson BD, Brooks NA, Brooks HB, Chan EM, De Dios A, Gilmour R, Graff JR, Jambrina E, Mader M, McCann D, Na S, Parsons SH, Pratt SE, Shih C, Stancato LF, Starling JJ, Tate C, Velasco JA, Wang Y, Ye XS.

Mol Cancer Ther. 2014 Feb;13(2):364-74. doi: 10.1158/1535-7163.MCT-13-0513. Epub 2013 Dec 19.

10.

Food colors and behavior.

Stevenson J, Sonuga-Barke E, Warner J, McCann D.

Curr Opin Pediatr. 2013 Aug;25(4):549-50. doi: 10.1097/MOP.0b013e328363187c. No abstract available.

PMID:
23838760
11.

Barriers to, and facilitators of, parenting programmes for childhood behaviour problems: a qualitative synthesis of studies of parents' and professionals' perceptions.

Koerting J, Smith E, Knowles MM, Latter S, Elsey H, McCann DC, Thompson M, Sonuga-Barke EJ.

Eur Child Adolesc Psychiatry. 2013 Nov;22(11):653-70. doi: 10.1007/s00787-013-0401-2. Epub 2013 Apr 6.

12.

Pharmacokinetics, metabolism, and excretion of the glycogen synthase kinase-3 inhibitor LY2090314 in rats, dogs, and humans: a case study in rapid clearance by extensive metabolism with low circulating metabolite exposure.

Zamek-Gliszczynski MJ, Abraham TL, Alberts JJ, Kulanthaivel P, Jackson KA, Chow KH, McCann DJ, Hu H, Anderson S, Furr NA, Barbuch RJ, Cassidy KC.

Drug Metab Dispos. 2013 Apr;41(4):714-26. doi: 10.1124/dmd.112.048488. Epub 2013 Jan 10.

13.

Growing your wealth: paths to pursue, pitfalls to avoid.

McCann D.

CDS Rev. 2012 Sep-Oct;105(5):20-1. No abstract available.

PMID:
23061227
14.

Infliximab-associated Blastomycosis dermatitidis in treatment of ulcerative colitis.

McCann DA, Smith HL.

Colorectal Dis. 2013 Feb;15(2):e102-3. doi: 10.1111/codi.12050. No abstract available.

PMID:
23046403
15.

Interprofessional and integrated care of the elderly in a family health team.

Moore A, Patterson C, White J, House ST, Riva JJ, Nair K, Brown A, Kadhim-Saleh A, McCann D.

Can Fam Physician. 2012 Aug;58(8):e436-41.

16.

The daily patterns of time use for parents of children with complex needs: a systematic review.

McCann D, Bull R, Winzenberg T.

J Child Health Care. 2012 Mar;16(1):26-52. doi: 10.1177/1367493511420186. Epub 2012 Feb 3. Review.

PMID:
22308543
17.

A novel, nonbinary evaluation of success and failure reveals bupropion efficacy versus methamphetamine dependence: reanalysis of a multisite trial.

McCann DJ, Li SH.

CNS Neurosci Ther. 2012 May;18(5):414-8. doi: 10.1111/j.1755-5949.2011.00263.x. Epub 2011 Oct 18.

PMID:
22070720
18.

A novel, selective inhibitor of fibroblast growth factor receptors that shows a potent broad spectrum of antitumor activity in several tumor xenograft models.

Zhao G, Li WY, Chen D, Henry JR, Li HY, Chen Z, Zia-Ebrahimi M, Bloem L, Zhai Y, Huss K, Peng SB, McCann DJ.

Mol Cancer Ther. 2011 Nov;10(11):2200-10. doi: 10.1158/1535-7163.MCT-11-0306. Epub 2011 Sep 7.

19.

Managing change in the care of children with complex needs: healthcare providers' perspectives.

Law J, McCann D, O'May F.

J Adv Nurs. 2011 Dec;67(12):2551-60. doi: 10.1111/j.1365-2648.2011.05761.x. Epub 2011 Jul 20.

PMID:
21771038
20.

Early detection and intervention for attention-deficit/hyperactivity disorder.

Sonuga-Barke EJ, Koerting J, Smith E, McCann DC, Thompson M.

Expert Rev Neurother. 2011 Apr;11(4):557-63. doi: 10.1586/ern.11.39. Review.

PMID:
21469928
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