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Results: 1 to 20 of 140

1.

Fulfilling the Promise of 'Biased' GPCR Agonism.

Luttrell LM, Maudsley S, Bohn LM.

Mol Pharmacol. 2015 Jul 1. pii: mol.115.099630. [Epub ahead of print]

2.

Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.

Maudsley S, Martin B, Janssens J, Etienne H, Jushaj A, van Gastel J, Willemsen A, Chen H, Gesty-Palmer D, Luttrell LM.

Methods. 2015 May 16. pii: S1046-2023(15)00206-6. doi: 10.1016/j.ymeth.2015.05.013. [Epub ahead of print]

PMID:
25986936
3.

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Maudsley S, Martin B, Gesty-Palmer D, Cheung H, Johnson C, Patel S, Becker KG, Wood WH 3rd, Zhang Y, Lehrmann E, Luttrell LM.

Mol Pharmacol. 2015 Apr;87(4):706-17. doi: 10.1124/mol.114.095224. Epub 2015 Jan 30.

4.

Nuclear GIT2 is an ATM substrate and promotes DNA repair.

Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.

Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20.

PMID:
25605334
5.

Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.

Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH 3rd, Becker KG, Martin B, Maudsley S.

J Biol Chem. 2015 Jan 30;290(5):2728-43. doi: 10.1074/jbc.M114.588608. Epub 2014 Dec 11.

PMID:
25505248
6.

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.

Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ.

J Exp Med. 2014 Nov 17;211(12):2373-83. doi: 10.1084/jem.20140116. Epub 2014 Nov 3.

7.

Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor System.

Janssens J, Etienne H, Idriss S, Azmi A, Martin B, Maudsley S.

Front Endocrinol (Lausanne). 2014 Sep 1;5:142. doi: 10.3389/fendo.2014.00142. eCollection 2014. Review.

8.

The effects of aging on the BTBR mouse model of autism spectrum disorder.

Jasien JM, Daimon CM, Wang R, Shapiro BK, Martin B, Maudsley S.

Front Aging Neurosci. 2014 Sep 1;6:225. doi: 10.3389/fnagi.2014.00225. eCollection 2014.

9.

Higher TNF-α, IGF-1, and Leptin Levels are Found in Tasters than Non-Tasters.

Wang R, van Keeken NM, Siddiqui S, Dijksman LM, Maudsley S, Derval D, van Dam PS, Martin B.

Front Endocrinol (Lausanne). 2014 Jul 29;5:125. doi: 10.3389/fendo.2014.00125. eCollection 2014.

10.

Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients.

Wang R, Ross CA, Cai H, Cong WN, Daimon CM, Carlson OD, Egan JM, Siddiqui S, Maudsley S, Martin B.

Front Physiol. 2014 Jun 23;5:231. doi: 10.3389/fphys.2014.00231. eCollection 2014.

11.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R.

Cell Metab. 2014 Jul 1;20(1):183-90. doi: 10.1016/j.cmet.2014.04.018. Epub 2014 May 29.

12.

What is the role of metabolic hormones in taste buds of the tongue.

Cai H, Maudsley S, Martin B.

Front Horm Res. 2014;42:134-46. doi: 10.1159/000358322. Epub 2014 Apr 7. Review.

PMID:
24732931
13.

Pharmacophore model of the quercetin binding site of the SIRT6 protein.

Ravichandran S, Singh N, Donnelly D, Migliore M, Johnson P, Fishwick C, Luke BT, Martin B, Maudsley S, Fugmann SD, Moaddel R.

J Mol Graph Model. 2014 Apr;49:38-46. doi: 10.1016/j.jmgm.2014.01.004. Epub 2014 Jan 20.

14.

The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases.

Daimon CM, Chirdon P, Maudsley S, Martin B.

Am J Alzheimers Dis (Columbia). 2013;1(1). doi: 10.7726/ajad.2013.1003.

15.

Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism.

Okun E, Griffioen KJ, Rothman S, Wan R, Cong WN, De Cabo R, Martin-Montalvo A, Levette A, Maudsley S, Martin B, Arumugam TV, Mattson MP.

Brain Behav Immun. 2014 Feb;36:90-100. doi: 10.1016/j.bbi.2013.10.013. Epub 2013 Oct 18.

16.

Altered lipid and salt taste responsivity in ghrelin and GOAT null mice.

Cai H, Cong WN, Daimon CM, Wang R, Tschöp MH, Sévigny J, Martin B, Maudsley S.

PLoS One. 2013 Oct 4;8(10):e76553. doi: 10.1371/journal.pone.0076553. eCollection 2013.

17.

Longitudinal analysis of calorie restriction on rat taste bud morphology and expression of sweet taste modulators.

Cai H, Daimon CM, Cong WN, Wang R, Chirdon P, de Cabo R, Sévigny J, Maudsley S, Martin B.

J Gerontol A Biol Sci Med Sci. 2014 May;69(5):532-44. doi: 10.1093/gerona/glt129. Epub 2013 Sep 28.

18.

Long-term artificial sweetener acesulfame potassium treatment alters neurometabolic functions in C57BL/6J mice.

Cong WN, Wang R, Cai H, Daimon CM, Scheibye-Knudsen M, Bohr VA, Turkin R, Wood WH 3rd, Becker KG, Moaddel R, Maudsley S, Martin B.

PLoS One. 2013 Aug 7;8(8):e70257. doi: 10.1371/journal.pone.0070257. eCollection 2013.

19.

Plurigon: three dimensional visualization and classification of high-dimensionality data.

Martin B, Chen H, Daimon CM, Chadwick W, Siddiqui S, Maudsley S.

Front Physiol. 2013 Jul 22;4:190. doi: 10.3389/fphys.2013.00190. eCollection 2013.

20.

Systems analysis of arrestin pathway functions.

Maudsley S, Siddiqui S, Martin B.

Prog Mol Biol Transl Sci. 2013;118:431-67. doi: 10.1016/B978-0-12-394440-5.00017-6. Review.

PMID:
23764064
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