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Items: 1 to 20 of 145

1.

GIT2 Acts as a Systems-Level Coordinator of Neurometabolic Activity and Pathophysiological Aging.

Martin B, Chadwick W, Janssens J, Premont RT, Schmalzigaug R, Becker KG, Lehrmann E, Wood WH, Zhang Y, Siddiqui S, Park SS, Cong WN, Daimon CM, Maudsley S.

Front Endocrinol (Lausanne). 2016 Jan 18;6:191. doi: 10.3389/fendo.2015.00191. eCollection 2015.

2.

Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder.

Daimon CM, Jasien JM, Wood WH 3rd, Zhang Y, Becker KG, Silverman JL, Crawley JN, Martin B, Maudsley S.

Front Physiol. 2015 Nov 24;6:324. doi: 10.3389/fphys.2015.00324. eCollection 2015.

3.

Investigating the role of filamin C in Belgian patients with frontotemporal dementia linked to GRN deficiency in FTLD-TDP brains.

Janssens J, Philtjens S, Kleinberger G, Van Mossevelde S, van der Zee J, Cacace R, Engelborghs S, Sieben A, Banzhaf-Strathmann J, Dillen L, Merlin C, Cuijt I, Robberecht C, Schmid B, Santens P, Ivanoiu A, Vandenbulcke M, Vandenberghe R, Cras P, De Deyn PP, Martin JJ, Maudsley S, Haass C, Cruts M, Van Broeckhoven C; Belgian Neurology (BELNEU) consortium.

Acta Neuropathol Commun. 2015 Nov 10;3:68. doi: 10.1186/s40478-015-0246-7.

4.

Human Obesity Associated with an Intronic SNP in the Brain-Derived Neurotrophic Factor Locus.

Mou Z, Hyde TM, Lipska BK, Martinowich K, Wei P, Ong CJ, Hunter LA, Palaguachi GI, Morgun E, Teng R, Lai C, Condarco TA, Demidowich AP, Krause AJ, Marshall LJ, Haack K, Voruganti VS, Cole SA, Butte NF, Comuzzie AG, Nalls MA, Zonderman AB, Singleton AB, Evans MK, Martin B, Maudsley S, Tsao JW, Kleinman JE, Yanovski JA, Han JC.

Cell Rep. 2015 Nov 10;13(6):1073-80. doi: 10.1016/j.celrep.2015.09.065. Epub 2015 Oct 29.

5.

Recessive mutations in SLC13A5 result in a loss of citrate transport and cause neonatal epilepsy, developmental delay and teeth hypoplasia.

Hardies K, de Kovel CG, Weckhuysen S, Asselbergh B, Geuens T, Deconinck T, Azmi A, May P, Brilstra E, Becker F, Barisic N, Craiu D, Braun KP, Lal D, Thiele H, Schubert J, Weber Y, van 't Slot R, Nürnberg P, Balling R, Timmerman V, Lerche H, Maudsley S, Helbig I, Suls A, Koeleman BP, De Jonghe P; autosomal recessive working group of the EuroEPINOMICS RES Consortium.

Brain. 2015 Nov;138(Pt 11):3238-50. doi: 10.1093/brain/awv263. Epub 2015 Sep 17.

PMID:
26384929
6.

Fulfilling the Promise of "Biased" G Protein-Coupled Receptor Agonism.

Luttrell LM, Maudsley S, Bohn LM.

Mol Pharmacol. 2015 Sep;88(3):579-88. doi: 10.1124/mol.115.099630. Epub 2015 Jul 1. Review.

PMID:
26134495
7.

Informatic deconvolution of biased GPCR signaling mechanisms from in vivo pharmacological experimentation.

Maudsley S, Martin B, Janssens J, Etienne H, Jushaj A, van Gastel J, Willemsen A, Chen H, Gesty-Palmer D, Luttrell LM.

Methods. 2016 Jan 1;92:51-63. doi: 10.1016/j.ymeth.2015.05.013. Epub 2015 May 16.

PMID:
25986936
8.

Delineation of a conserved arrestin-biased signaling repertoire in vivo.

Maudsley S, Martin B, Gesty-Palmer D, Cheung H, Johnson C, Patel S, Becker KG, Wood WH 3rd, Zhang Y, Lehrmann E, Luttrell LM.

Mol Pharmacol. 2015 Apr;87(4):706-17. doi: 10.1124/mol.114.095224. Epub 2015 Jan 30.

9.

Nuclear GIT2 is an ATM substrate and promotes DNA repair.

Lu D, Cai H, Park SS, Siddiqui S, Premont RT, Schmalzigaug R, Paramasivam M, Seidman M, Bodogai I, Biragyn A, Daimon CM, Martin B, Maudsley S.

Mol Cell Biol. 2015 Apr;35(7):1081-96. doi: 10.1128/MCB.01432-14. Epub 2015 Jan 20.

10.

Amitriptyline improves motor function via enhanced neurotrophin signaling and mitochondrial functions in the murine N171-82Q Huntington disease model.

Cong WN, Chadwick W, Wang R, Daimon CM, Cai H, Amma J, Wood WH 3rd, Becker KG, Martin B, Maudsley S.

J Biol Chem. 2015 Jan 30;290(5):2728-43. doi: 10.1074/jbc.M114.588608. Epub 2014 Dec 11.

11.

Adiposity induces lethal cytokine storm after systemic administration of stimulatory immunotherapy regimens in aged mice.

Mirsoian A, Bouchlaka MN, Sckisel GD, Chen M, Pai CC, Maverakis E, Spencer RG, Fishbein KW, Siddiqui S, Monjazeb AM, Martin B, Maudsley S, Hesdorffer C, Ferrucci L, Longo DL, Blazar BR, Wiltrout RH, Taub DD, Murphy WJ.

J Exp Med. 2014 Nov 17;211(12):2373-83. doi: 10.1084/jem.20140116. Epub 2014 Nov 3.

12.

Systems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor System.

Janssens J, Etienne H, Idriss S, Azmi A, Martin B, Maudsley S.

Front Endocrinol (Lausanne). 2014 Sep 1;5:142. doi: 10.3389/fendo.2014.00142. eCollection 2014. Review.

13.

The effects of aging on the BTBR mouse model of autism spectrum disorder.

Jasien JM, Daimon CM, Wang R, Shapiro BK, Martin B, Maudsley S.

Front Aging Neurosci. 2014 Sep 1;6:225. doi: 10.3389/fnagi.2014.00225. eCollection 2014.

14.

Higher TNF-α, IGF-1, and Leptin Levels are Found in Tasters than Non-Tasters.

Wang R, van Keeken NM, Siddiqui S, Dijksman LM, Maudsley S, Derval D, van Dam PS, Martin B.

Front Endocrinol (Lausanne). 2014 Jul 29;5:125. doi: 10.3389/fendo.2014.00125. eCollection 2014.

15.

Metabolic and hormonal signatures in pre-manifest and manifest Huntington's disease patients.

Wang R, Ross CA, Cai H, Cong WN, Daimon CM, Carlson OD, Egan JM, Siddiqui S, Maudsley S, Martin B.

Front Physiol. 2014 Jun 23;5:231. doi: 10.3389/fphys.2014.00231. eCollection 2014.

16.

Resveratrol prevents high fat/sucrose diet-induced central arterial wall inflammation and stiffening in nonhuman primates.

Mattison JA, Wang M, Bernier M, Zhang J, Park SS, Maudsley S, An SS, Santhanam L, Martin B, Faulkner S, Morrell C, Baur JA, Peshkin L, Sosnowska D, Csiszar A, Herbert RL, Tilmont EM, Ungvari Z, Pearson KJ, Lakatta EG, de Cabo R.

Cell Metab. 2014 Jul 1;20(1):183-90. doi: 10.1016/j.cmet.2014.04.018. Epub 2014 May 29.

17.

What is the role of metabolic hormones in taste buds of the tongue.

Cai H, Maudsley S, Martin B.

Front Horm Res. 2014;42:134-46. doi: 10.1159/000358322. Epub 2014 Apr 7. Review.

PMID:
24732931
18.

Pharmacophore model of the quercetin binding site of the SIRT6 protein.

Ravichandran S, Singh N, Donnelly D, Migliore M, Johnson P, Fishwick C, Luke BT, Martin B, Maudsley S, Fugmann SD, Moaddel R.

J Mol Graph Model. 2014 Apr;49:38-46. doi: 10.1016/j.jmgm.2014.01.004. Epub 2014 Jan 20.

19.

The role of Thyrotropin Releasing Hormone in aging and neurodegenerative diseases.

Daimon CM, Chirdon P, Maudsley S, Martin B.

Am J Alzheimers Dis (Columbia). 2013;1(1). doi: 10.7726/ajad.2013.1003.

20.

Toll-like receptors 2 and 4 modulate autonomic control of heart rate and energy metabolism.

Okun E, Griffioen KJ, Rothman S, Wan R, Cong WN, De Cabo R, Martin-Montalvo A, Levette A, Maudsley S, Martin B, Arumugam TV, Mattson MP.

Brain Behav Immun. 2014 Feb;36:90-100. doi: 10.1016/j.bbi.2013.10.013. Epub 2013 Oct 18.

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