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Results: 1 to 20 of 45

1.

A high-throughput cell-based method to predict the unbound drug fraction in the brain.

Mateus A, Matsson P, Artursson P.

J Med Chem. 2014 Apr 10;57(7):3005-10. doi: 10.1021/jm401963n. Epub 2014 Mar 20.

PMID:
24601604
[PubMed - indexed for MEDLINE]
Free PMC Article
2.

Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.

Over B, McCarren P, Artursson P, Foley M, Giordanetto F, Grönberg G, Hilgendorf C, Lee MD 4th, Matsson P, Muncipinto G, Pellisson M, Perry MW, Svensson R, Duvall JR, Kihlberg J.

J Med Chem. 2014 Mar 27;57(6):2746-54. doi: 10.1021/jm500059t. Epub 2014 Feb 26.

PMID:
24524242
[PubMed - indexed for MEDLINE]
Free PMC Article
3.

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Pedersen JM, Matsson P, Bergström CA, Hoogstraate J, Norén A, LeCluyse EL, Artursson P.

Toxicol Sci. 2013 Dec;136(2):328-43. doi: 10.1093/toxsci/kft197. Epub 2013 Sep 6.

PMID:
24014644
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Rapid measurement of intracellular unbound drug concentrations.

Mateus A, Matsson P, Artursson P.

Mol Pharm. 2013 Jun 3;10(6):2467-78. doi: 10.1021/mp4000822. Epub 2013 May 15.

PMID:
23631740
[PubMed - indexed for MEDLINE]
Free Article
5.

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.

Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium.

Clin Pharmacol Ther. 2013 Jul;94(1):126-41. doi: 10.1038/clpt.2013.78. Epub 2013 Apr 10. Review.

PMID:
23588320
[PubMed - indexed for MEDLINE]
Free PMC Article
6.

Computational prospecting for drug-transporter interactions.

Matsson P, Artursson P.

Clin Pharmacol Ther. 2013 Jul;94(1):30-2. doi: 10.1038/clpt.2013.67. Epub 2013 Apr 2. No abstract available.

PMID:
23588306
[PubMed - indexed for MEDLINE]
7.

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides.

Hansson M, Mathsson L, Schlederer T, Israelsson L, Matsson P, Nogueira L, Jakobsson PJ, Lundberg K, Malmström V, Serre G, Holmdahl R, Nystrand M, Klareskog L, Rönnelid J.

Arthritis Res Ther. 2012 Oct 1;14(5):R201. doi: 10.1186/ar4039.

PMID:
23025688
[PubMed - in process]
Free PMC Article
8.

Population-based study of multiplexed IgE sensitization in relation to asthma, exhaled nitric oxide, and bronchial responsiveness.

Patelis A, Gunnbjörnsdottir M, Malinovschi A, Matsson P, Onell A, Högman M, Alving K, Janson C.

J Allergy Clin Immunol. 2012 Aug;130(2):397-402.e2. doi: 10.1016/j.jaci.2012.03.046. Epub 2012 May 26.

PMID:
22633327
[PubMed - indexed for MEDLINE]
9.

Is there a future for multiplexed technologies in the point-of-care setting?

Matsson P.

Bioanalysis. 2011 Sep;3(18):2049-52. doi: 10.4155/bio.11.200. No abstract available.

PMID:
21942514
[PubMed - indexed for MEDLINE]
Free Article
10.

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Kido Y, Matsson P, Giacomini KM.

J Med Chem. 2011 Jul 14;54(13):4548-58. doi: 10.1021/jm2001629. Epub 2011 Jun 8.

PMID:
21599003
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM.

Pharmacogenomics J. 2012 Jun;12(3):214-26. doi: 10.1038/tpj.2011.8. Epub 2011 Mar 8.

PMID:
21383772
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Allergen cross reactions: a problem greater than ever thought?

Pfiffner P, Truffer R, Matsson P, Rasi C, Mari A, Stadler BM.

Allergy. 2010 Dec;65(12):1536-44. doi: 10.1111/j.1398-9995.2010.02420.x.

PMID:
20584004
[PubMed - indexed for MEDLINE]
13.

Comparison of human solute carriers.

Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A.

Protein Sci. 2010 Mar;19(3):412-28. doi: 10.1002/pro.320.

PMID:
20052679
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Understanding polymer-lipid solid dispersions--the properties of incorporated lipids govern the crystallisation behaviour of PEG.

Unga J, Matsson P, Mahlin D.

Int J Pharm. 2010 Feb 15;386(1-2):61-70. doi: 10.1016/j.ijpharm.2009.10.049. Epub 2009 Nov 10.

PMID:
19900523
[PubMed - indexed for MEDLINE]
15.

Genetic variation in the proximal promoter of ABC and SLC superfamilies: liver and kidney specific expression and promoter activity predict variation.

Hesselson SE, Matsson P, Shima JE, Fukushima H, Yee SW, Kobayashi Y, Gow JM, Ha C, Ma B, Poon A, Johns SJ, Stryke D, Castro RA, Tahara H, Choi JH, Chen L, Picard N, Sjödin E, Roelofs MJ, Ferrin TE, Myers R, Kroetz DL, Kwok PY, Giacomini KM.

PLoS One. 2009 Sep 9;4(9):e6942. doi: 10.1371/journal.pone.0006942.

PMID:
19742321
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Identification of novel specific and general inhibitors of the three major human ATP-binding cassette transporters P-gp, BCRP and MRP2 among registered drugs.

Matsson P, Pedersen JM, Norinder U, Bergström CA, Artursson P.

Pharm Res. 2009 Aug;26(8):1816-31. doi: 10.1007/s11095-009-9896-0. Epub 2009 May 7.

PMID:
19421845
[PubMed - indexed for MEDLINE]
17.

Structural requirements for drug inhibition of the liver specific human organic cation transport protein 1.

Ahlin G, Karlsson J, Pedersen JM, Gustavsson L, Larsson R, Matsson P, Norinder U, Bergström CA, Artursson P.

J Med Chem. 2008 Oct 9;51(19):5932-42. doi: 10.1021/jm8003152. Epub 2008 Sep 13.

PMID:
18788725
[PubMed - indexed for MEDLINE]
18.

Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).

Pedersen JM, Matsson P, Bergström CA, Norinder U, Hoogstraate J, Artursson P.

J Med Chem. 2008 Jun 12;51(11):3275-87. doi: 10.1021/jm7015683. Epub 2008 May 6.

PMID:
18457386
[PubMed - indexed for MEDLINE]
19.

Multivariate statistical analysis of large-scale IgE antibody measurements reveals allergen extract relationships in sensitized individuals.

Soeria-Atmadja D, Onell A, Kober A, Matsson P, Gustafsson MG, Hammerling U.

J Allergy Clin Immunol. 2007 Dec;120(6):1433-40. Epub 2007 Sep 7.

PMID:
17825892
[PubMed - indexed for MEDLINE]
20.

A global drug inhibition pattern for the human ATP-binding cassette transporter breast cancer resistance protein (ABCG2).

Matsson P, Englund G, Ahlin G, Bergström CA, Norinder U, Artursson P.

J Pharmacol Exp Ther. 2007 Oct;323(1):19-30. Epub 2007 Jul 6.

PMID:
17616561
[PubMed - indexed for MEDLINE]
Free Article

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