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Items: 1 to 20 of 52

1.

Cell permeability beyond the rule of 5.

Matsson P, Doak BC, Over B, Kihlberg J.

Adv Drug Deliv Rev. 2016 Apr 9. pii: S0169-409X(16)30099-0. doi: 10.1016/j.addr.2016.03.013. [Epub ahead of print] Review.

PMID:
27067608
2.

The Need for Speed-Kinetic Limits of Drug Transporters.

Matsson P, Lundquist P, Artursson P.

Trends Pharmacol Sci. 2016 Apr;37(4):243-5. doi: 10.1016/j.tips.2016.02.002. Epub 2016 Feb 24. No abstract available.

PMID:
26922253
3.

Complete Knockout of Endogenous Mdr1 (Abcb1) in MDCK Cells by CRISPR-Cas9.

Simoff I, Karlgren M, Backlund M, Lindström AC, Gaugaz FZ, Matsson P, Artursson P.

J Pharm Sci. 2016 Feb;105(2):1017-21. doi: 10.1016/S0022-3549(15)00171-9.

PMID:
26869442
4.

The Proteome of Filter-Grown Caco-2 Cells With a Focus on Proteins Involved in Drug Disposition.

Ölander M, Wiśniewski JR, Matsson P, Lundquist P, Artursson P.

J Pharm Sci. 2016 Feb;105(2):817-27. doi: 10.1016/j.xphs.2015.10.030. Epub 2016 Jan 9.

PMID:
26869432
5.

Computational modeling to predict the functions and impact of drug transporters.

Matsson P, Bergström CA.

In Silico Pharmacol. 2015 Dec;3(1):8. doi: 10.1186/s40203-015-0012-3. Epub 2015 Sep 4.

6.

Addendum to 'Quantifying the impact of transporters on cellular drug permeability'.

Matsson P, Fenu LA, Lundquist P, Wiśniewski JR, Kansy M, Artursson P.

Trends Pharmacol Sci. 2015 Sep;36(9):559. doi: 10.1016/j.tips.2015.06.009. Epub 2015 Jul 24. No abstract available.

PMID:
26216247
7.

Quantifying the impact of transporters on cellular drug permeability.

Matsson P, Fenu LA, Lundquist P, Wiśniewski JR, Kansy M, Artursson P.

Trends Pharmacol Sci. 2015 May;36(5):255-62. doi: 10.1016/j.tips.2015.02.009. Epub 2015 Mar 19. Review. Erratum in: Trends Pharmacol Sci. 2015 Sep;36(9):559.

PMID:
25799456
8.

A high-throughput cell-based method to predict the unbound drug fraction in the brain.

Mateus A, Matsson P, Artursson P.

J Med Chem. 2014 Apr 10;57(7):3005-10. doi: 10.1021/jm401963n. Epub 2014 Mar 20.

9.

Impact of stereospecific intramolecular hydrogen bonding on cell permeability and physicochemical properties.

Over B, McCarren P, Artursson P, Foley M, Giordanetto F, Grönberg G, Hilgendorf C, Lee MD 4th, Matsson P, Muncipinto G, Pellisson M, Perry MW, Svensson R, Duvall JR, Kihlberg J.

J Med Chem. 2014 Mar 27;57(6):2746-54. doi: 10.1021/jm500059t. Epub 2014 Feb 26.

10.

Early identification of clinically relevant drug interactions with the human bile salt export pump (BSEP/ABCB11).

Pedersen JM, Matsson P, Bergström CA, Hoogstraate J, Norén A, LeCluyse EL, Artursson P.

Toxicol Sci. 2013 Dec;136(2):328-43. doi: 10.1093/toxsci/kft197. Epub 2013 Sep 6.

11.

Rapid measurement of intracellular unbound drug concentrations.

Mateus A, Matsson P, Artursson P.

Mol Pharm. 2013 Jun 3;10(6):2467-78. doi: 10.1021/mp4000822. Epub 2013 May 15.

12.

Intracellular drug concentrations and transporters: measurement, modeling, and implications for the liver.

Chu X, Korzekwa K, Elsby R, Fenner K, Galetin A, Lai Y, Matsson P, Moss A, Nagar S, Rosania GR, Bai JP, Polli JW, Sugiyama Y, Brouwer KL; International Transporter Consortium.

Clin Pharmacol Ther. 2013 Jul;94(1):126-41. doi: 10.1038/clpt.2013.78. Epub 2013 Apr 10. Review.

13.

Computational prospecting for drug-transporter interactions.

Matsson P, Artursson P.

Clin Pharmacol Ther. 2013 Jul;94(1):30-2. doi: 10.1038/clpt.2013.67. Epub 2013 Apr 2. No abstract available.

PMID:
23588306
14.

Validation of a multiplex chip-based assay for the detection of autoantibodies against citrullinated peptides.

Hansson M, Mathsson L, Schlederer T, Israelsson L, Matsson P, Nogueira L, Jakobsson PJ, Lundberg K, Malmström V, Serre G, Holmdahl R, Nystrand M, Klareskog L, Rönnelid J.

Arthritis Res Ther. 2012 Oct 1;14(5):R201. doi: 10.1186/ar4039.

15.

Population-based study of multiplexed IgE sensitization in relation to asthma, exhaled nitric oxide, and bronchial responsiveness.

Patelis A, Gunnbjörnsdottir M, Malinovschi A, Matsson P, Onell A, Högman M, Alving K, Janson C.

J Allergy Clin Immunol. 2012 Aug;130(2):397-402.e2. doi: 10.1016/j.jaci.2012.03.046. Epub 2012 May 26.

PMID:
22633327
16.

Is there a future for multiplexed technologies in the point-of-care setting?

Matsson P.

Bioanalysis. 2011 Sep;3(18):2049-52. doi: 10.4155/bio.11.200. No abstract available.

17.

Profiling of a prescription drug library for potential renal drug-drug interactions mediated by the organic cation transporter 2.

Kido Y, Matsson P, Giacomini KM.

J Med Chem. 2011 Jul 14;54(13):4548-58. doi: 10.1021/jm2001629. Epub 2011 Jun 8.

18.

Discovery of regulatory elements in human ATP-binding cassette transporters through expression quantitative trait mapping.

Matsson P, Yee SW, Markova S, Morrissey K, Jenkins G, Xuan J, Jorgenson E, Kroetz DL, Giacomini KM.

Pharmacogenomics J. 2012 Jun;12(3):214-26. doi: 10.1038/tpj.2011.8. Epub 2011 Mar 8.

19.

Allergen cross reactions: a problem greater than ever thought?

Pfiffner P, Truffer R, Matsson P, Rasi C, Mari A, Stadler BM.

Allergy. 2010 Dec;65(12):1536-44. doi: 10.1111/j.1398-9995.2010.02420.x.

20.

Comparison of human solute carriers.

Schlessinger A, Matsson P, Shima JE, Pieper U, Yee SW, Kelly L, Apeltsin L, Stroud RM, Ferrin TE, Giacomini KM, Sali A.

Protein Sci. 2010 Mar;19(3):412-28. doi: 10.1002/pro.320.

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