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A systems biology approach reveals the dose- and time-dependent effect of primary human airway epithelium tissue culture after exposure to cigarette smoke in vitro.

Mathis C, Gebel S, Poussin C, Belcastro V, Sewer A, Weisensee D, Hengstermann A, Ansari S, Wagner S, Peitsch MC, Hoeng J.

Bioinform Biol Insights. 2015 Mar 9;9:19-35. doi: 10.4137/BBI.S19908. eCollection 2015.


Subjective Cognitive Complaints, Personality and Brain Amyloid-beta in Cognitively Normal Older Adults.

Snitz BE, Weissfeld LA, Cohen AD, Lopez OL, Nebes RD, Aizenstein HJ, McDade E, Price JC, Mathis CA, Klunk WE.

Am J Geriatr Psychiatry. 2015 Feb 11. pii: S1064-7481(15)00083-4. doi: 10.1016/j.jagp.2015.01.008. [Epub ahead of print]


Impact assessment of repeated exposure of organotypic 3D bronchial and nasal tissue culture models to whole cigarette smoke.

Kuehn D, Majeed S, Guedj E, Dulize R, Baumer K, Iskandar A, Boue S, Martin F, Kostadinova R, Mathis C, Ivanov NV, Frentzel S, Hoeng J, Peitsch MC.

J Vis Exp. 2015 Feb 12;(96). doi: 10.3791/52325.


Touchscreen tasks in mice to demonstrate differences between hippocampal and striatal functions.

Delotterie DF, Mathis C, Cassel JC, Rosenbrock H, Dorner-Ciossek C, Marti A.

Neurobiol Learn Mem. 2015 Apr;120:16-27. doi: 10.1016/j.nlm.2015.02.007. Epub 2015 Feb 14.


[Breast cancer screening in thirteen French departments].

Ouédraogo S, Dabakuyo-Yonli TS, Roussot A, Dialla PO, Pornet C, Poillot ML, Soler-Michel P, Sarlin N, Lunaud P, Desmidt P, Paré E, Mathis C, Rymzhanova R, Kuntz-Huon J, Exbrayat C, Bataillard A, Régnier V, Kalecinski J, Quantin C, Dumas A, Gentil J, Amiel P, Chauvin F, Dancourt V, Arveux P.

Bull Cancer. 2015 Feb;102(2):126-38. doi: 10.1016/j.bulcan.2014.07.002. Epub 2015 Jan 27. French.


Is Charismatic Leadership Effective When Workers Are Pressured To Be Good Citizens?

Horn D, Mathis CJ, Robinson SL, Randle N.

J Psychol. 2014 Dec 9:1-24. [Epub ahead of print]


γ-Hydroxybutyrate (Xyrem) ameliorates clinical symptoms and neuropathology in a mouse model of Alzheimer's disease.

Klein C, Mathis C, Leva G, Patte-Mensah C, Cassel JC, Maitre M, Mensah-Nyagan AG.

Neurobiol Aging. 2015 Feb;36(2):832-44. doi: 10.1016/j.neurobiolaging.2014.10.003. Epub 2014 Oct 13.


The Centiloid Project: standardizing quantitative amyloid plaque estimation by PET.

Klunk WE, Koeppe RA, Price JC, Benzinger TL, Devous MD Sr, Jagust WJ, Johnson KA, Mathis CA, Minhas D, Pontecorvo MJ, Rowe CC, Skovronsky DM, Mintun MA.

Alzheimers Dement. 2015 Jan;11(1):1-15.e1-4. doi: 10.1016/j.jalz.2014.07.003. Epub 2014 Oct 28.


Amyloid, neurodegeneration, and small vessel disease as predictors of dementia in the oldest-old.

Lopez OL, Klunk WE, Mathis C, Coleman RL, Price J, Becker JT, Aizenstein HJ, Snitz B, Cohen A, Ikonomovic M, McDade E, DeKosky ST, Weissfeld L, Kuller LH.

Neurology. 2014 Nov 11;83(20):1804-11. doi: 10.1212/WNL.0000000000000977. Epub 2014 Oct 10.


The response of human nasal and bronchial organotypic tissue cultures to repeated whole cigarette smoke exposure.

Talikka M, Kostadinova R, Xiang Y, Mathis C, Sewer A, Majeed S, Kuehn D, Frentzel S, Merg C, Geertz M, Martin F, Ivanov NV, Peitsch MC, Hoeng J.

Int J Toxicol. 2014 Nov-Dec;33(6):506-17. doi: 10.1177/1091581814551647. Epub 2014 Oct 8.


Regional amyloid burden and intrinsic connectivity networks in cognitively normal elderly subjects.

Lim HK, Nebes R, Snitz B, Cohen A, Mathis C, Price J, Weissfeld L, Klunk W, Aizenstein HJ.

Brain. 2014 Dec;137(Pt 12):3327-38. doi: 10.1093/brain/awu271. Epub 2014 Sep 29.


Understanding the limits of animal models as predictors of human biology: lessons learned from the sbv IMPROVER Species Translation Challenge.

Rhrissorrakrai K, Belcastro V, Bilal E, Norel R, Poussin C, Mathis C, Dulize RH, Ivanov NV, Alexopoulos L, Rice JJ, Peitsch MC, Stolovitzky G, Meyer P, Hoeng J.

Bioinformatics. 2015 Feb 15;31(4):471-83. doi: 10.1093/bioinformatics/btu611. Epub 2014 Sep 17.


Functional connectivity in autosomal dominant and late-onset Alzheimer disease.

Thomas JB, Brier MR, Bateman RJ, Snyder AZ, Benzinger TL, Xiong C, Raichle M, Holtzman DM, Sperling RA, Mayeux R, Ghetti B, Ringman JM, Salloway S, McDade E, Rossor MN, Ourselin S, Schofield PR, Masters CL, Martins RN, Weiner MW, Thompson PM, Fox NC, Koeppe RA, Jack CR Jr, Mathis CA, Oliver A, Blazey TM, Moulder K, Buckles V, Hornbeck R, Chhatwal J, Schultz AP, Goate AM, Fagan AM, Cairns NJ, Marcus DS, Morris JC, Ances BM.

JAMA Neurol. 2014 Sep;71(9):1111-22. doi: 10.1001/jamaneurol.2014.1654.


In vitro systems toxicology approach to investigate the effects of repeated cigarette smoke exposure on human buccal and gingival organotypic epithelial tissue cultures.

Schlage WK, Iskandar AR, Kostadinova R, Xiang Y, Sewer A, Majeed S, Kuehn D, Frentzel S, Talikka M, Geertz M, Mathis C, Ivanov N, Hoeng J, Peitsch MC.

Toxicol Mech Methods. 2014 Oct;24(7):470-87. doi: 10.3109/15376516.2014.943441. Epub 2014 Sep 11.


Cerebral perfusion alterations and cerebral amyloid in autosomal dominant Alzheimer disease.

McDade E, Kim A, James J, Sheu LK, Kuan DC, Minhas D, Gianaros PJ, Ikonomovic S, Lopez O, Snitz B, Price J, Becker J, Mathis C, Klunk W.

Neurology. 2014 Aug 19;83(8):710-7. doi: 10.1212/WNL.0000000000000721. Epub 2014 Jul 16.


A vascular biology network model focused on inflammatory processes to investigate atherogenesis and plaque instability.

De León H, Boué S, Schlage WK, Boukharov N, Westra JW, Gebel S, VanHooser A, Talikka M, Fields RB, Veljkovic E, Peck MJ, Mathis C, Hoang V, Poussin C, Deehan R, Stolle K, Hoeng J, Peitsch MC.

J Transl Med. 2014 Jun 26;12:185. doi: 10.1186/1479-5876-12-185.


Optimization of touchscreen-based behavioral paradigms in mice: implications for building a battery of tasks taxing learning and memory functions.

Delotterie D, Mathis C, Cassel JC, Dorner-Ciossek C, Marti A.

PLoS One. 2014 Jun 24;9(6):e100817. doi: 10.1371/journal.pone.0100817. eCollection 2014.


PDE9A inhibition rescues amyloid beta-induced deficits in synaptic plasticity and cognition.

Kroker KS, Mathis C, Marti A, Cassel JC, Rosenbrock H, Dorner-Ciossek C.

Neurobiol Aging. 2014 Sep;35(9):2072-8. doi: 10.1016/j.neurobiolaging.2014.03.023. Epub 2014 Mar 26.


Arterial stiffness and β-amyloid progression in nondemented elderly adults.

Hughes TM, Kuller LH, Barinas-Mitchell EJ, McDade EM, Klunk WE, Cohen AD, Mathis CA, Dekosky ST, Price JC, Lopez OL.

JAMA Neurol. 2014 May;71(5):562-8. doi: 10.1001/jamaneurol.2014.186.


Defective response inhibition and collicular noradrenaline enrichment in mice with duplicated retinotopic map in the superior colliculus.

Mathis C, Savier E, Bott JB, Clesse D, Bevins N, Sage-Ciocca D, Geiger K, Gillet A, Laux-Biehlmann A, Goumon Y, Lacaud A, Lelièvre V, Kelche C, Cassel JC, Pfrieger FW, Reber M.

Brain Struct Funct. 2015 May;220(3):1573-84. doi: 10.1007/s00429-014-0745-5. Epub 2014 Mar 20.

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