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Combined blockade of angiotensin II and prorenin receptors ameliorates podocytic apoptosis induced by IgA-activated mesangial cells.

Leung JC, Chan LY, Saleem MA, Mathieson PW, Tang SC, Lai KN.

Apoptosis. 2015 Mar 26. [Epub ahead of print]


Levamisole in steroid-sensitive nephrotic syndrome: usefulness in adult patients and laboratory insights into mechanisms of action via direct action on the kidney podocyte.

Jiang L, Dasgupta I, Hurcombe JA, Colyer HF, Mathieson PW, Welsh GI.

Clin Sci (Lond). 2015 Jun;128(12):883-93. doi: 10.1042/CS20140749.


Hyperglycemia enhances kidney cell injury in HIVAN through down-regulation of vitamin D receptors.

Rai P, Singh T, Lederman R, Chawla A, Kumar D, Cheng K, Valecha G, Mathieson PW, Saleem MA, Malhotra A, Singhal PC.

Cell Signal. 2015 Mar;27(3):460-9. doi: 10.1016/j.cellsig.2014.12.011. Epub 2014 Dec 24.


Matrix metalloproteinase 9-mediated shedding of syndecan 4 in response to tumor necrosis factor α: a contributor to endothelial cell glycocalyx dysfunction.

Ramnath R, Foster RR, Qiu Y, Cope G, Butler MJ, Salmon AH, Mathieson PW, Coward RJ, Welsh GI, Satchell SC.

FASEB J. 2014 Nov;28(11):4686-99. doi: 10.1096/fj.14-252221. Epub 2014 Aug 13.


Localization of APOL1 protein and mRNA in the human kidney: nondiseased tissue, primary cells, and immortalized cell lines.

Ma L, Shelness GS, Snipes JA, Murea M, Antinozzi PA, Cheng D, Saleem MA, Satchell SC, Banas B, Mathieson PW, Kretzler M, Hemal AK, Rudel LL, Petrovic S, Weckerle A, Pollak MR, Ross MD, Parks JS, Freedman BI.

J Am Soc Nephrol. 2015 Feb;26(2):339-48. doi: 10.1681/ASN.2013091017. Epub 2014 Jul 10.


APOL1 risk variants enhance podocyte necrosis through compromising lysosomal membrane permeability.

Lan X, Jhaveri A, Cheng K, Wen H, Saleem MA, Mathieson PW, Mikulak J, Aviram S, Malhotra A, Skorecki K, Singhal PC.

Am J Physiol Renal Physiol. 2014 Aug 1;307(3):F326-36. doi: 10.1152/ajprenal.00647.2013. Epub 2014 Jun 4.


Glomerular cell cross-talk influences composition and assembly of extracellular matrix.

Byron A, Randles MJ, Humphries JD, Mironov A, Hamidi H, Harris S, Mathieson PW, Saleem MA, Satchell SC, Zent R, Humphries MJ, Lennon R.

J Am Soc Nephrol. 2014 May;25(5):953-66. doi: 10.1681/ASN.2013070795. Epub 2014 Jan 16.


Immunosuppression for membranous nephropathy - Authors' reply.

Mathieson PW.

Lancet. 2013 Jun 22;381(9884):2163. doi: 10.1016/S0140-6736(13)61436-1. No abstract available.


Glycosaminoglycan regulation by VEGFA and VEGFC of the glomerular microvascular endothelial cell glycocalyx in vitro.

Foster RR, Armstrong L, Baker S, Wong DW, Wylie EC, Ramnath R, Jenkins R, Singh A, Steadman R, Welsh GI, Mathieson PW, Satchell SC.

Am J Pathol. 2013 Aug;183(2):604-16. doi: 10.1016/j.ajpath.2013.04.019. Epub 2013 Jun 12.


Insulin directly stimulates VEGF-A production in the glomerular podocyte.

Hale LJ, Hurcombe J, Lay A, Santamaría B, Valverde AM, Saleem MA, Mathieson PW, Welsh GI, Coward RJ.

Am J Physiol Renal Physiol. 2013 Jul 15;305(2):F182-8. doi: 10.1152/ajprenal.00548.2012. Epub 2013 May 22.


Serum from minimal change patients in relapse increases CD80 expression in cultured podocytes.

Ishimoto T, Cara-Fuentes G, Wang H, Shimada M, Wasserfall CH, Winter WE, Rivard CJ, Araya CE, Saleem MA, Mathieson PW, Johnson RJ, Garin EH.

Pediatr Nephrol. 2013 Sep;28(9):1803-12. doi: 10.1007/s00467-013-2498-4. Epub 2013 May 21.


mTOR plays a critical role in p53-induced oxidative kidney cell injury in HIVAN.

Rai P, Plagov A, Lan X, Chandel N, Singh T, Lederman R, Ayasolla KR, Mathieson PW, Saleem MA, Husain M, Malhotra A, Chander PN, Singhal PC.

Am J Physiol Renal Physiol. 2013 Aug 1;305(3):F343-54. doi: 10.1152/ajprenal.00135.2013. Epub 2013 May 15.


Rapamycin-induced modulation of miRNA expression is associated with amelioration of HIV-associated nephropathy (HIVAN).

Cheng K, Rai P, Plagov A, Lan X, Mathieson PW, Saleem MA, Husain M, Malhotra A, Singhal PC.

Exp Cell Res. 2013 Aug 1;319(13):2073-80. doi: 10.1016/j.yexcr.2013.04.011. Epub 2013 Apr 21.


Morphine induces albuminuria by compromising podocyte integrity.

Lan X, Rai P, Chandel N, Cheng K, Lederman R, Saleem MA, Mathieson PW, Husain M, Crosson JT, Gupta K, Malhotra A, Singhal PC.

PLoS One. 2013;8(3):e55748. doi: 10.1371/journal.pone.0055748. Epub 2013 Mar 29.


HIV compromises integrity of the podocyte actin cytoskeleton through downregulation of the vitamin D receptor.

Chandel N, Sharma B, Husain M, Salhan D, Singh T, Rai P, Mathieson PW, Saleem MA, Malhotra A, Singhal PC.

Am J Physiol Renal Physiol. 2013 Jun 1;304(11):F1347-57. doi: 10.1152/ajprenal.00717.2012. Epub 2013 Mar 6.


Reactive oxygen species modulate the barrier function of the human glomerular endothelial glycocalyx.

Singh A, Ramnath RD, Foster RR, Wylie EC, Fridén V, Dasgupta I, Haraldsson B, Welsh GI, Mathieson PW, Satchell SC.

PLoS One. 2013;8(2):e55852. doi: 10.1371/journal.pone.0055852. Epub 2013 Feb 14.


Phospholipase A2 receptor (PLA2R1) sequence variants in idiopathic membranous nephropathy.

Coenen MJ, Hofstra JM, Debiec H, Stanescu HC, Medlar AJ, Stengel B, Boland-Augé A, Groothuismink JM, Bockenhauer D, Powis SH, Mathieson PW, Brenchley PE, Kleta R, Wetzels JF, Ronco P.

J Am Soc Nephrol. 2013 Mar;24(4):677-83. doi: 10.1681/ASN.2012070730. Epub 2013 Feb 21.


Immunosuppression for progressive membranous nephropathy: a UK randomised controlled trial.

Howman A, Chapman TL, Langdon MM, Ferguson C, Adu D, Feehally J, Gaskin GJ, Jayne DR, O'Donoghue D, Boulton-Jones M, Mathieson PW.

Lancet. 2013 Mar 2;381(9868):744-51. doi: 10.1016/S0140-6736(12)61566-9. Epub 2013 Jan 9.


Insulin-like growth factor-II is produced by, signals to and is an important survival factor for the mature podocyte in man and mouse.

Hale LJ, Welsh GI, Perks CM, Hurcombe JA, Moore S, Hers I, Saleem MA, Mathieson PW, Murphy AJ, Jeansson M, Holly JM, Hardouin SN, Coward RJ.

J Pathol. 2013 May;230(1):95-106. doi: 10.1002/path.4165. Epub 2013 Mar 21.


Membranous nephropathy.

Mathieson PW.

Clin Med. 2012 Oct;12(5):461-6. No abstract available.

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