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Effect of Laparoscopic-Assisted Resection vs Open Resection on Pathological Outcomes in Rectal Cancer: The ALaCaRT Randomized Clinical Trial.

Stevenson AR, Solomon MJ, Lumley JW, Hewett P, Clouston AD, Gebski VJ, Davies L, Wilson K, Hague W, Simes J; ALaCaRT Investigators.

JAMA. 2015 Oct 6;314(13):1356-63. doi: 10.1001/jama.2015.12009.


Flexible regression models for rate differences, risk differences and relative risks.

Donoghoe MW, Marschner IC.

Int J Biostat. 2015 May;11(1):91-108. doi: 10.1515/ijb-2014-0044.


Efficacy and safety of LDL-lowering therapy among men and women: meta-analysis of individual data from 174,000 participants in 27 randomised trials.

Cholesterol Treatment Trialists' (CTT) Collaboration, Fulcher J, O'Connell R, Voysey M, Emberson J, Blackwell L, Mihaylova B, Simes J, Collins R, Kirby A, Colhoun H, Braunwald E, La Rosa J, Pedersen TR, Tonkin A, Davis B, Sleight P, Franzosi MG, Baigent C, Keech A.

Lancet. 2015 Apr 11;385(9976):1397-405. doi: 10.1016/S0140-6736(14)61368-4. Epub 2015 Jan 9.


Letter to the editor.

Marschner IC.

Biostatistics. 2015 Jan;16(1):1-2. doi: 10.1093/biostatistics/kxu025. Epub 2014 Jul 24. No abstract available.


Randomized controlled trial of oxygen saturation targets in very preterm infants: two year outcomes.

Darlow BA, Marschner SL, Donoghoe M, Battin MR, Broadbent RS, Elder MJ, Hewson MP, Meyer MP, Ghadge A, Graham P, McNeill NJ, Kuschel CA, Tarnow-Mordi WO; Benefits Of Oxygen Saturation Targeting-New Zealand (BOOST-NZ) Collaborative Group.

J Pediatr. 2014 Jul;165(1):30-35.e2. doi: 10.1016/j.jpeds.2014.01.017. Epub 2014 Feb 20.


Changes in lipoprotein-Associated phospholipase A2 activity predict coronary events and partly account for the treatment effect of pravastatin: results from the Long-Term Intervention with Pravastatin in Ischemic Disease study.

White HD, Simes J, Stewart RA, Blankenberg S, Barnes EH, Marschner IC, Thompson P, West M, Zeller T, Colquhoun DM, Nestel P, Keech AC, Sullivan DR, Hunt D, Tonkin A; LIPID Study Investigators.

J Am Heart Assoc. 2013 Oct 23;2(5):e000360. doi: 10.1161/JAHA.113.000360.


Meta-analysis of clinical trials with early stopping: an investigation of potential bias.

Schou IM, Marschner IC.

Stat Med. 2013 Dec 10;32(28):4859-74. doi: 10.1002/sim.5893. Epub 2013 Jul 3. Review.


Oxygen saturation and outcomes in preterm infants.

BOOST II United Kingdom Collaborative Group; BOOST II Australia Collaborative Group; BOOST II New Zealand Collaborative Group, Stenson BJ, Tarnow-Mordi WO, Darlow BA, Simes J, Juszczak E, Askie L, Battin M, Bowler U, Broadbent R, Cairns P, Davis PG, Deshpande S, Donoghoe M, Doyle L, Fleck BW, Ghadge A, Hague W, Halliday HL, Hewson M, King A, Kirby A, Marlow N, Meyer M, Morley C, Simmer K, Tin W, Wardle SP, Brocklehurst P.

N Engl J Med. 2013 May 30;368(22):2094-104. doi: 10.1056/NEJMoa1302298. Epub 2013 May 5.


The effects of lowering LDL cholesterol with statin therapy in people at low risk of vascular disease: meta-analysis of individual data from 27 randomised trials.

Cholesterol Treatment Trialists' (CTT) Collaborators, Mihaylova B, Emberson J, Blackwell L, Keech A, Simes J, Barnes EH, Voysey M, Gray A, Collins R, Baigent C.

Lancet. 2012 Aug 11;380(9841):581-90. doi: 10.1016/S0140-6736(12)60367-5. Epub 2012 May 17.


Increase in cholesterol predicts survival advantage in renal cell carcinoma patients treated with temsirolimus.

Lee CK, Marschner IC, Simes RJ, Voysey M, Egleston B, Hudes G, de Souza P.

Clin Cancer Res. 2012 Jun 1;18(11):3188-96. doi: 10.1158/1078-0432.CCR-11-3137. Epub 2012 Apr 3.


Lack of effect of lowering LDL cholesterol on cancer: meta-analysis of individual data from 175,000 people in 27 randomised trials of statin therapy.

Cholesterol Treatment Trialists' (CTT) Collaboration, Emberson JR, Kearney PM, Blackwell L, Newman C, Reith C, Bhala N, Holland L, Peto R, Keech A, Collins R, Simes J, Baigent C.

PLoS One. 2012;7(1):e29849. doi: 10.1371/journal.pone.0029849. Epub 2012 Jan 19.


Relative risk regression: reliable and flexible methods for log-binomial models.

Marschner IC, Gillett AC.

Biostatistics. 2012 Jan;13(1):179-92. doi: 10.1093/biostatistics/kxr030. Epub 2011 Sep 13.


Assessment of statistical heterogeneity in the PLATO trial.

Buyse M, Marschner IC.

Cardiology. 2011;118(2):138; author reply 139. doi: 10.1159/000327592. Epub 2011 May 18. No abstract available.


A systematic review and meta-analysis of KRAS status as the determinant of response to anti-EGFR antibodies and the impact of partner chemotherapy in metastatic colorectal cancer.

Adelstein BA, Dobbins TA, Harris CA, Marschner IC, Ward RL.

Eur J Cancer. 2011 Jun;47(9):1343-54. doi: 10.1016/j.ejca.2011.03.031. Epub 2011 May 5. Review.


Efficacy and safety of more intensive lowering of LDL cholesterol: a meta-analysis of data from 170,000 participants in 26 randomised trials.

Cholesterol Treatment Trialists’ (CTT) Collaboration, Baigent C, Blackwell L, Emberson J, Holland LE, Reith C, Bhala N, Peto R, Barnes EH, Keech A, Simes J, Collins R.

Lancet. 2010 Nov 13;376(9753):1670-81. doi: 10.1016/S0140-6736(10)61350-5. Epub 2010 Nov 8.


Pregabalin versus gabapentin in partial epilepsy: a meta-analysis of dose-response relationships.

Delahoy P, Thompson S, Marschner IC.

BMC Neurol. 2010 Nov 1;10:104. doi: 10.1186/1471-2377-10-104.


Unexplained international differences in clinical outcomes after acute myocardial infarction and fibrinolytic therapy: lessons from the Hirulog and Early Reperfusion or Occlusion (HERO)-2 trial.

Simes RJ, O'Connell RL, Aylward PE, Varshavsky S, Diaz R, Wilcox RG, Armstrong PW, Granger CB, French JK, Van de Werf F, Marschner IC, Califf R, White HD; HERO-2 Investigators.

Am Heart J. 2010 Jun;159(6):988-97. doi: 10.1016/j.ahj.2009.12.044.


Semi-parametric risk prediction models for recurrent cardiovascular events in the LIPID study.

Cui J, Forbes A, Kirby A, Marschner I, Simes J, Hunt D, West M, Tonkin A.

BMC Med Res Methodol. 2010 Apr 1;10:27. doi: 10.1186/1471-2288-10-27.


Design and rationale of a study in Asia of atorvastatin pretreatment in patients undergoing percutaneous coronary intervention for non-ST elevation acute coronary syndromes.

Ge J, Kim YJ, Jang YS, Zhu J, Marschner IC, Lam W.

J Cardiol. 2010 May;55(3):303-8. doi: 10.1016/j.jjcc.2009.12.002. Epub 2010 Jan 8.


Regional differences in multinational clinical trials: anticipating chance variation.

Marschner IC.

Clin Trials. 2010 Apr;7(2):147-56. doi: 10.1177/1740774510361974. Epub 2010 Mar 25.

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