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Results: 1 to 20 of 56

1.

Recent progress in sodium channel modulators for pain.

Bagal SK, Chapman ML, Marron BE, Prime R, Storer RI, Swain NA.

Bioorg Med Chem Lett. 2014 Aug 15;24(16):3690-9. doi: 10.1016/j.bmcl.2014.06.038. Epub 2014 Jun 21. Review.

2.

Voltage sensor interaction site for selective small molecule inhibitors of voltage-gated sodium channels.

McCormack K, Santos S, Chapman ML, Krafte DS, Marron BE, West CW, Krambis MJ, Antonio BM, Zellmer SG, Printzenhoff D, Padilla KM, Lin Z, Wagoner PK, Swain NA, Stupple PA, de Groot M, Butt RP, Castle NA.

Proc Natl Acad Sci U S A. 2013 Jul 16;110(29):E2724-32. doi: 10.1073/pnas.1220844110. Epub 2013 Jul 1.

3.

Pharmacovigilance as a tool for safety and monitoring: a review of general issues and the specific challenges with end-stage renal failure patients.

Jacob D, Marrón B, Ehrlich J, Rutherford PA.

Drug Healthc Patient Saf. 2013 Apr 15;5:105-12. doi: 10.2147/DHPS.S43104. Print 2013.

4.

Effect of self-administered intraperitoneal bemiparin on peritoneal transport and ultrafiltration capacity in peritoneal dialysis patients with membrane dysfunction. A randomized, multi-centre open clinical trial.

Del Peso G, Bajo MA, Fontán MP, Martínez J, Marrón B, Selgas R; Group of Study on Bemidextrin.

Nephrol Dial Transplant. 2012 May;27(5):2051-8. doi: 10.1093/ndt/gfr546. Epub 2011 Oct 12.

5.

Discovery and biological evaluation of potent, selective, orally bioavailable, pyrazine-based blockers of the Na(v)1.8 sodium channel with efficacy in a model of neuropathic pain.

Scanio MJ, Shi L, Drizin I, Gregg RJ, Atkinson RN, Thomas JB, Johnson MS, Chapman ML, Liu D, Krambis MJ, Liu Y, Shieh CC, Zhang X, Simler GH, Joshi S, Honore P, Marsh KC, Knox A, Werness S, Antonio B, Krafte DS, Jarvis MF, Faltynek CR, Marron BE, Kort ME.

Bioorg Med Chem. 2010 Nov 15;18(22):7816-25. doi: 10.1016/j.bmc.2010.09.057. Epub 2010 Sep 29.

PMID:
20965738
6.

Subtype-selective Na(v)1.8 sodium channel blockers: identification of potent, orally active nicotinamide derivatives.

Kort ME, Atkinson RN, Thomas JB, Drizin I, Johnson MS, Secrest MA, Gregg RJ, Scanio MJ, Shi L, Hakeem AH, Matulenko MA, Chapman ML, Krambis MJ, Liu D, Shieh CC, Zhang X, Simler G, Mikusa JP, Zhong C, Joshi S, Honore P, Roeloffs R, Werness S, Antonio B, Marsh KC, Faltynek CR, Krafte DS, Jarvis MF, Marron BE.

Bioorg Med Chem Lett. 2010 Nov 15;20(22):6812-5. doi: 10.1016/j.bmcl.2010.08.121. Epub 2010 Sep 18.

PMID:
20855211
7.

A-887826 is a structurally novel, potent and voltage-dependent Na(v)1.8 sodium channel blocker that attenuates neuropathic tactile allodynia in rats.

Zhang XF, Shieh CC, Chapman ML, Matulenko MA, Hakeem AH, Atkinson RN, Kort ME, Marron BE, Joshi S, Honore P, Faltynek CR, Krafte DS, Jarvis MF.

Neuropharmacology. 2010 Sep;59(3):201-7. doi: 10.1016/j.neuropharm.2010.05.009. Epub 2010 Jun 1.

PMID:
20566409
8.

A deletion mutation in bovine SLC4A2 is associated with osteopetrosis in Red Angus cattle.

Meyers SN, McDaneld TG, Swist SL, Marron BM, Steffen DJ, O'Toole D, O'Connell JR, Beever JE, Sonstegard TS, Smith TP.

BMC Genomics. 2010 May 27;11:337. doi: 10.1186/1471-2164-11-337.

9.

A study of hydrogenated carbon fibers by scanning electron microscopy and confocal laser scanning microscopy.

de la Cal AM, Aguado-Serrano J, Rojas-Cervantes ML, Adame EV, Marron BS, Rosende AC, Nevshupa R.

Microsc Res Tech. 2009 Jun;72(6):447-53. doi: 10.1002/jemt.20690.

PMID:
19208389
10.

[Theoretical bases for the proposal of a randomized, controlled, open label clinical trial to assess the efficacy of adding bemiparin to the icodextrin solution in patients on peritoneal dialysis with peritoneal transport disorders [FRIAT-BEM-2005-01]].

Selgas R, Del Peso G, Sánchez Villanueva R, Aroeira LS, Fernández Perpén A, Ortiz A, Ruiz Ortega M, Sánchez-Tomero JA, Martínez J, Marrón B, Bajo MA.

Nefrologia. 2008;28 Suppl 6:51-8. Spanish.

PMID:
18957013
11.

Additive effects of soluble TWEAK and inflammation on mortality in hemodialysis patients.

Carrero JJ, Ortiz A, Qureshi AR, Martín-Ventura JL, Bárány P, Heimbürger O, Marrón B, Metry G, Snaedal S, Lindholm B, Egido J, Stenvinkel P, Blanco-Colio LM.

Clin J Am Soc Nephrol. 2009 Jan;4(1):110-8. doi: 10.2215/CJN.02790608. Epub 2008 Oct 22.

12.

Block of Nav1.8 by small molecules.

Krafte DS, Chapman M, Marron B, Atkinson R, Liu Y, Ye F, Curran M, Kort M, Jarvis MF.

Channels (Austin). 2007 May-Jun;1(3):152-3. Epub 2007 Jul 18.

13.

Creating porcine biomedical models through recombineering.

Rogatcheva MM, Rund LA, Swanson KS, Marron BM, Beever JE, Counter CM, Schook LB.

Comp Funct Genomics. 2004;5(3):262-7. doi: 10.1002/cfg.404.

14.

Icodextrin does not impact infectious and culture-negative peritonitis rates in peritoneal dialysis patients: a 2-year multicentre, comparative, prospective cohort study.

Vychytil A, Remón C, Michel C, Williams P, Rodríguez-Carmona A, Marrón B, Vonesh E, van der Heyden S, Divino Filho JC; Extraneal Peritonitis Study Group.

Nephrol Dial Transplant. 2008 Nov;23(11):3711-9. doi: 10.1093/ndt/gfn322. Epub 2008 Jun 13.

15.

Discovery of potent furan piperazine sodium channel blockers for treatment of neuropathic pain.

Drizin I, Gregg RJ, Scanio MJ, Shi L, Gross MF, Atkinson RN, Thomas JB, Johnson MS, Carroll WA, Marron BE, Chapman ML, Liu D, Krambis MJ, Shieh CC, Zhang X, Hernandez G, Gauvin DM, Mikusa JP, Zhu CZ, Joshi S, Honore P, Marsh KC, Roeloffs R, Werness S, Krafte DS, Jarvis MF, Faltynek CR, Kort ME.

Bioorg Med Chem. 2008 Jun 15;16(12):6379-86. doi: 10.1016/j.bmc.2008.05.003. Epub 2008 May 6.

PMID:
18501613
16.

Benefits of preserving residual renal function in peritoneal dialysis.

Marrón B, Remón C, Pérez-Fontán M, Quirós P, Ortíz A.

Kidney Int Suppl. 2008 Apr;(108):S42-51. doi: 10.1038/sj.ki.5002600. Review.

17.

Piggy-BACing the human genome I: constructing a porcine BAC physical map through comparative genomics.

Rogatcheva MB, Chen K, Larkin DM, Meyers SN, Marron BM, He W, Schook LB, Beever JE.

Anim Biotechnol. 2008;19(1):28-42. doi: 10.1080/10495390701807634.

PMID:
18228174
18.

Discovery and biological evaluation of 5-aryl-2-furfuramides, potent and selective blockers of the Nav1.8 sodium channel with efficacy in models of neuropathic and inflammatory pain.

Kort ME, Drizin I, Gregg RJ, Scanio MJ, Shi L, Gross MF, Atkinson RN, Johnson MS, Pacofsky GJ, Thomas JB, Carroll WA, Krambis MJ, Liu D, Shieh CC, Zhang X, Hernandez G, Mikusa JP, Zhong C, Joshi S, Honore P, Roeloffs R, Marsh KC, Murray BP, Liu J, Werness S, Faltynek CR, Krafte DS, Jarvis MF, Chapman ML, Marron BE.

J Med Chem. 2008 Feb 14;51(3):407-16. doi: 10.1021/jm070637u. Epub 2008 Jan 5.

PMID:
18176998
19.

[Systemic and renal effects of preventing contrast nephrotoxicity with isotonic (0.9%) and hypotonic (0.45%) saline].

Marrón B, Ruiz E, Fernández C, Almeida P, Horcajada C, Navarro F, Caramelo C.

Rev Esp Cardiol. 2007 Oct;60(10):1018-25. Spanish.

20.

A high utility integrated map of the pig genome.

Humphray SJ, Scott CE, Clark R, Marron B, Bender C, Camm N, Davis J, Jenks A, Noon A, Patel M, Sehra H, Yang F, Rogatcheva MB, Milan D, Chardon P, Rohrer G, Nonneman D, de Jong P, Meyers SN, Archibald A, Beever JE, Schook LB, Rogers J.

Genome Biol. 2007;8(7):R139.

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