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Results: 1 to 20 of 118

1.

RNA-Seq Identifies Novel Myocardial Gene Expression Signatures of Heart Failure.

Liu Y, Morley M, Brandimarto J, Hannenhalli S, Hu Y, Ashley EA, Tang WH, Moravec CS, Margulies KB, Cappola TP, Li M; for the MAGNet consortium.

Genomics. 2014 Dec 17. pii: S0888-7543(14)00268-7. doi: 10.1016/j.ygeno.2014.12.002. [Epub ahead of print]

PMID:
25528681
[PubMed - as supplied by publisher]
2.

A needleless liquid jet injection delivery method for cardiac gene therapy: a comparative evaluation versus standard routes of delivery reveals enhanced therapeutic retention and cardiac specific gene expression.

Fargnoli AS, Katz MG, Williams RD, Margulies KB, Bridges CR.

J Cardiovasc Transl Res. 2014 Nov;7(8):756-67. doi: 10.1007/s12265-014-9593-1. Epub 2014 Oct 15.

PMID:
25315468
[PubMed - in process]
3.

Enhanced bioactive myocardial transforming growth factor-β in advanced human heart failure.

Khan S, Joyce J, Margulies KB, Tsuda T.

Circ J. 2014;78(11):2711-8. Epub 2014 Oct 9.

PMID:
25298166
[PubMed - in process]
Free Article
4.

Cardioprotection by controlling hyperamylinemia in a "humanized" diabetic rat model.

Despa S, Sharma S, Harris TR, Dong H, Li N, Chiamvimonvat N, Taegtmeyer H, Margulies KB, Hammock BD, Despa F.

J Am Heart Assoc. 2014 Aug 21;3(4). pii: e001015. doi: 10.1161/JAHA.114.001015.

PMID:
25146704
[PubMed - in process]
Free Article
5.

Emerging Tools for Computer-Aided Diagnosis and Prognostication.

Ritter S, Margulies KB.

J Clin Trials. 2014 Feb 24;4(2):e117. No abstract available.

PMID:
25143872
[PubMed]
Free PMC Article
6.

Epigenetic memory and cardiac cell therapy.

Alvarez RM, Margulies KB.

J Am Coll Cardiol. 2014 Aug 5;64(5):449-50. doi: 10.1016/j.jacc.2014.05.021. No abstract available.

PMID:
25082576
[PubMed - indexed for MEDLINE]
7.

GLP-1 agonist therapy for advanced heart failure with reduced ejection fraction: design and rationale for the functional impact of GLP-1 for heart failure treatment study.

Margulies KB, Anstrom KJ, Hernandez AF, Redfield MM, Shah MR, Braunwald E, Cappola TP; Heart Failure Clinical Research Network.

Circ Heart Fail. 2014 Jul;7(4):673-9. doi: 10.1161/CIRCHEARTFAILURE.114.000346. Review. No abstract available.

PMID:
25028349
[PubMed - indexed for MEDLINE]
8.

Anti-inflammatory loaded poly-lactic glycolic acid nanoparticle formulations to enhance myocardial gene transfer: an in-vitro assessment of a drug/gene combination therapeutic approach for direct injection.

Fargnoli AS, Mu A, Katz MG, Williams RD, Margulies KB, Weiner DB, Yang S, Bridges CR.

J Transl Med. 2014 Jun 16;12:171. doi: 10.1186/1479-5876-12-171.

PMID:
24934216
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

A bioengineered hydrogel system enables targeted and sustained intramyocardial delivery of neuregulin, activating the cardiomyocyte cell cycle and enhancing ventricular function in a murine model of ischemic cardiomyopathy.

Cohen JE, Purcell BP, MacArthur JW Jr, Mu A, Shudo Y, Patel JB, Brusalis CM, Trubelja A, Fairman AS, Edwards BB, Davis MS, Hung G, Hiesinger W, Atluri P, Margulies KB, Burdick JA, Woo YJ.

Circ Heart Fail. 2014 Jul;7(4):619-26. doi: 10.1161/CIRCHEARTFAILURE.113.001273. Epub 2014 Jun 5.

PMID:
24902740
[PubMed - indexed for MEDLINE]
10.

Dynamic left ventricular assist device inflow obstruction.

Birati EY, Kirkpatrick JN, Rame JE, Bala R, Margulies KB.

Circ Heart Fail. 2014 Jan;7(1):225-6. doi: 10.1161/CIRCHEARTFAILURE.113.000941. No abstract available.

PMID:
24449814
[PubMed - indexed for MEDLINE]
11.

Low-dose dopamine or low-dose nesiritide in acute heart failure with renal dysfunction: the ROSE acute heart failure randomized trial.

Chen HH, Anstrom KJ, Givertz MM, Stevenson LW, Semigran MJ, Goldsmith SR, Bart BA, Bull DA, Stehlik J, LeWinter MM, Konstam MA, Huggins GS, Rouleau JL, O'Meara E, Tang WH, Starling RC, Butler J, Deswal A, Felker GM, O'Connor CM, Bonita RE, Margulies KB, Cappola TP, Ofili EO, Mann DL, Dávila-Román VG, McNulty SE, Borlaug BA, Velazquez EJ, Lee KL, Shah MR, Hernandez AF, Braunwald E, Redfield MM; NHLBI Heart Failure Clinical Research Network.

JAMA. 2013 Dec 18;310(23):2533-43. doi: 10.1001/jama.2013.282190.

PMID:
24247300
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Gene expression and genetic variation in human atria.

Lin H, Dolmatova EV, Morley MP, Lunetta KL, McManus DD, Magnani JW, Margulies KB, Hakonarson H, del Monte F, Benjamin EJ, Cappola TP, Ellinor PT.

Heart Rhythm. 2014 Feb;11(2):266-71. doi: 10.1016/j.hrthm.2013.10.051. Epub 2013 Oct 28.

PMID:
24177373
[PubMed - indexed for MEDLINE]
13.

BET bromodomains mediate transcriptional pause release in heart failure.

Anand P, Brown JD, Lin CY, Qi J, Zhang R, Artero PC, Alaiti MA, Bullard J, Alazem K, Margulies KB, Cappola TP, Lemieux M, Plutzky J, Bradner JE, Haldar SM.

Cell. 2013 Aug 1;154(3):569-82. doi: 10.1016/j.cell.2013.07.013.

PMID:
23911322
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Divergent mitochondrial biogenesis responses in human cardiomyopathy.

Ahuja P, Wanagat J, Wang Z, Wang Y, Liem DA, Ping P, Antoshechkin IA, Margulies KB, Maclellan WR.

Circulation. 2013 May 14;127(19):1957-67. doi: 10.1161/CIRCULATIONAHA.112.001219. Epub 2013 Apr 15.

PMID:
23589024
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Management of ventricular arrhythmias in patients with ventricular assist devices.

Pedrotty DM, Rame JE, Margulies KB.

Curr Opin Cardiol. 2013 May;28(3):360-8. doi: 10.1097/HCO.0b013e32835fb7dc. Review.

PMID:
23549232
[PubMed - indexed for MEDLINE]
16.

Hybrid mathematical model of cardiomyocyte turnover in the adult human heart.

Elser JA, Margulies KB.

PLoS One. 2012;7(12):e51683. doi: 10.1371/journal.pone.0051683. Epub 2012 Dec 19.

PMID:
23284740
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Synergistic effects of SDF-1α chemokine and hyaluronic acid release from degradable hydrogels on directing bone marrow derived cell homing to the myocardium.

Purcell BP, Elser JA, Mu A, Margulies KB, Burdick JA.

Biomaterials. 2012 Nov;33(31):7849-57. doi: 10.1016/j.biomaterials.2012.07.005. Epub 2012 Jul 24.

PMID:
22835643
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Animal models of heart failure: a scientific statement from the American Heart Association.

Houser SR, Margulies KB, Murphy AM, Spinale FG, Francis GS, Prabhu SD, Rockman HA, Kass DA, Molkentin JD, Sussman MA, Koch WJ; American Heart Association Council on Basic Cardiovascular Sciences, Council on Clinical Cardiology, and Council on Functional Genomics and Translational Biology.

Circ Res. 2012 Jun 22;111(1):131-50. doi: 10.1161/RES.0b013e3182582523. Epub 2012 May 17. Review. No abstract available. Erratum in: Circ Res. 2012 Jul 6;111(2):e54.

PMID:
22595296
[PubMed - indexed for MEDLINE]
Free Article
19.

Hyperamylinemia contributes to cardiac dysfunction in obesity and diabetes: a study in humans and rats.

Despa S, Margulies KB, Chen L, Knowlton AA, Havel PJ, Taegtmeyer H, Bers DM, Despa F.

Circ Res. 2012 Feb 17;110(4):598-608. doi: 10.1161/CIRCRESAHA.111.258285. Epub 2012 Jan 24.

PMID:
22275486
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Differential expression of PDE5 in failing and nonfailing human myocardium.

Shan X, Quaile MP, Monk JK, French B, Cappola TP, Margulies KB.

Circ Heart Fail. 2012 Jan;5(1):79-86. doi: 10.1161/CIRCHEARTFAILURE.111.961706. Epub 2011 Dec 1.

PMID:
22135403
[PubMed - indexed for MEDLINE]
Free PMC Article

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