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Results: 1 to 20 of 54

1.

Structure-based design of low-nanomolar PIM kinase inhibitors.

Ishchenko A, Zhang L, Le Brazidec JY, Fan J, Chong JH, Hingway A, Raditsis A, Singh L, Elenbaas B, Hong VS, Marcotte D, Silvian L, Enyedy I, Chao J.

Bioorg Med Chem Lett. 2015 Feb 1;25(3):474-80. doi: 10.1016/j.bmcl.2014.12.041. Epub 2014 Dec 19.

PMID:
25575657
[PubMed - in process]
2.

Tricyclic Covalent Inhibitors Selectively Target Jak3 Through an Active-site Thiol.

Goedken ER, Argiriadi MA, Banach DL, Fiamengo BA, Foley SE, Frank KE, George JS, Harris CM, Hobson AD, Ihle DC, Marcotte D, Merta PJ, Michalak ME, Murdock SE, Tomlinson MJ, Voss JW.

J Biol Chem. 2014 Dec 31. pii: jbc.M114.595181. [Epub ahead of print]

PMID:
25552479
[PubMed - as supplied by publisher]
Free Article
3.

Achieving cultural congruency in weight loss interventions: can a spirituality-based program attract and retain an inner-city community sample?

Davis C, Dutton WB, Durant T, Annunziato RA, Marcotte D.

J Obes. 2014;2014:641939. doi: 10.1155/2014/641939. Epub 2014 Apr 7.

PMID:
24804086
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

Patterns of substance use among HIV-positive adults over 50: implications for treatment and medication adherence.

Parsons JT, Starks TJ, Millar BM, Boonrai K, Marcotte D.

Drug Alcohol Depend. 2014 Jun 1;139:33-40. doi: 10.1016/j.drugalcdep.2014.02.704. Epub 2014 Mar 19.

PMID:
24745475
[PubMed - in process]
5.

[The temporal relationship between anxiety and depression during the school transition between primary and high-school].

Richard R, Marcotte D.

Sante Ment Que. 2013 Autumn;38(2):257-75. French.

PMID:
24719012
[PubMed - indexed for MEDLINE]
6.

La trajectoire des symptômes dépressifs de l'enfance à l'adolescence et les cibles d'intervention préventive.

Marcotte D, Lemieux A.

Cien Saude Colet. 2014 Mar;19(3):785-96. French. No abstract available.

PMID:
24714893
[PubMed - in process]
Free Article
7.

Small molecules inhibit the interaction of Nrf2 and the Keap1 Kelch domain through a non-covalent mechanism.

Marcotte D, Zeng W, Hus JC, McKenzie A, Hession C, Jin P, Bergeron C, Lugovskoy A, Enyedy I, Cuervo H, Wang D, Atmanene C, Roecklin D, Vecchi M, Vivat V, Kraemer J, Winkler D, Hong V, Chao J, Lukashev M, Silvian L.

Bioorg Med Chem. 2013 Jul 15;21(14):4011-9. doi: 10.1016/j.bmc.2013.04.019. Epub 2013 Apr 19.

PMID:
23647822
[PubMed - indexed for MEDLINE]
8.

Enabling structure-based drug design of Tyk2 through co-crystallization with a stabilizing aminoindazole inhibitor.

Argiriadi MA, Goedken ER, Banach D, Borhani DW, Burchat A, Dixon RW, Marcotte D, Overmeyer G, Pivorunas V, Sadhukhan R, Sousa S, Moore NS, Tomlinson M, Voss J, Wang L, Wishart N, Woller K, Talanian RV.

BMC Struct Biol. 2012 Sep 20;12:22. doi: 10.1186/1472-6807-12-22.

PMID:
22995073
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Structure-based design of 2,6,7-trisubstituted-7H-pyrrolo[2,3-d]pyrimidines as Aurora kinases inhibitors.

Le Brazidec JY, Pasis A, Tam B, Boykin C, Wang D, Marcotte DJ, Claassen G, Chong JH, Chao J, Fan J, Nguyen K, Silvian L, Ling L, Zhang L, Choi M, Teng M, Pathan N, Zhao S, Li T, Taveras A.

Bioorg Med Chem Lett. 2012 Jun 15;22(12):4033-7. doi: 10.1016/j.bmcl.2012.04.085. Epub 2012 Apr 25.

PMID:
22607669
[PubMed - indexed for MEDLINE]
10.

An inactivating caspase 11 passenger mutation originating from the 129 murine strain in mice targeted for c-IAP1.

Kenneth NS, Younger JM, Hughes ED, Marcotte D, Barker PA, Saunders TL, Duckett CS.

Biochem J. 2012 Apr 15;443(2):355-9. doi: 10.1042/BJ20120249.

PMID:
22332634
[PubMed - indexed for MEDLINE]
Free PMC Article
11.
12.

The STEM Pipeline: The Role of Summer Research Experience in Minority Students' Ph.D. Aspirations.

Pender M, Marcotte DE, Sto Domingo MR, Maton KI.

Educ Policy Anal Arch. 2010 Dec 10;18(30):1-36.

PMID:
21841903
[PubMed]
Free PMC Article
13.

Design, synthesis, and biological evaluation of pyrazolopyrimidine-sulfonamides as potent multiple-mitotic kinase (MMK) inhibitors (part I).

Zhang L, Fan J, Chong JH, Cesena A, Tam BY, Gilson C, Boykin C, Wang D, Aivazian D, Marcotte D, Xiao G, Le Brazidec JY, Piao J, Lundgren K, Hong K, Vu K, Nguyen K, Gan LS, Silvian L, Ling L, Teng M, Reff M, Takeda N, Timple N, Wang Q, Morena R, Khan S, Zhao S, Li T, Lee WC, Taveras AG, Chao J.

Bioorg Med Chem Lett. 2011 Sep 15;21(18):5633-7. doi: 10.1016/j.bmcl.2011.06.129. Epub 2011 Jul 13.

PMID:
21798738
[PubMed - indexed for MEDLINE]
14.

Discovery and characterization of non-ATP site inhibitors of the mitogen activated protein (MAP) kinases.

Comess KM, Sun C, Abad-Zapatero C, Goedken ER, Gum RJ, Borhani DW, Argiriadi M, Groebe DR, Jia Y, Clampit JE, Haasch DL, Smith HT, Wang S, Song D, Coen ML, Cloutier TE, Tang H, Cheng X, Quinn C, Liu B, Xin Z, Liu G, Fry EH, Stoll V, Ng TI, Banach D, Marcotte D, Burns DJ, Calderwood DJ, Hajduk PJ.

ACS Chem Biol. 2011 Mar 18;6(3):234-44. doi: 10.1021/cb1002619. Epub 2011 Jan 20.

PMID:
21090814
[PubMed - indexed for MEDLINE]
15.

Trace element analysis of rough diamond by LA-ICP-MS: a case of source discrimination?

Dalpé C, Hudon P, Ballantyne DJ, Williams D, Marcotte D.

J Forensic Sci. 2010 Nov;55(6):1443-56. doi: 10.1111/j.1556-4029.2010.01509.x.

PMID:
20681965
[PubMed]
16.

Structures of human Bruton's tyrosine kinase in active and inactive conformations suggest a mechanism of activation for TEC family kinases.

Marcotte DJ, Liu YT, Arduini RM, Hession CA, Miatkowski K, Wildes CP, Cullen PF, Hong V, Hopkins BT, Mertsching E, Jenkins TJ, Romanowski MJ, Baker DP, Silvian LF.

Protein Sci. 2010 Mar;19(3):429-39. doi: 10.1002/pro.321.

PMID:
20052711
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

A cure for crime? Psycho-pharmaceuticals and crime trends.

Marcotte DE, Markowitz S.

J Policy Anal Manage. 2010 Winter;30(1):29-56.

PMID:
21465827
[PubMed - indexed for MEDLINE]
18.

2,4-Diaminopyrimidine MK2 inhibitors. Part I: Observation of an unexpected inhibitor binding mode.

Argiriadi MA, Ericsson AM, Harris CM, Banach DL, Borhani DW, Calderwood DJ, Demers MD, Dimauro J, Dixon RW, Hardman J, Kwak S, Li B, Mankovich JA, Marcotte D, Mullen KD, Ni B, Pietras M, Sadhukhan R, Sousa S, Tomlinson MJ, Wang L, Xiang T, Talanian RV.

Bioorg Med Chem Lett. 2010 Jan 1;20(1):330-3. doi: 10.1016/j.bmcl.2009.10.102. Epub 2009 Oct 29.

PMID:
19919896
[PubMed - indexed for MEDLINE]
19.

Resting cerebral blood flow: a potential biomarker of the effects of HIV in the brain.

Ances BM, Sisti D, Vaida F, Liang CL, Leontiev O, Perthen JE, Buxton RB, Benson D, Smith DM, Little SJ, Richman DD, Moore DJ, Ellis RJ; HNRC group.

Neurology. 2009 Sep 1;73(9):702-8. doi: 10.1212/WNL.0b013e3181b59a97.

PMID:
19720977
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Anti-depressants and suicide.

Ludwig J, Marcotte DE, Norberg K.

J Health Econ. 2009 May;28(3):659-76. doi: 10.1016/j.jhealeco.2009.02.002. Epub 2009 Mar 3.

PMID:
19324439
[PubMed - indexed for MEDLINE]

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