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The SLE variant Ala71Thr of BLK severely decreases protein abundance and binding to BANK1 through impairment of the SH3 domain function.

Díaz-Barreiro A, Bernal-Quirós M, Georg I, Marañón C, Alarcón-Riquelme ME, Castillejo-López C.

Genes Immun. 2016 Jan 28. doi: 10.1038/gene.2016.1. [Epub ahead of print]


Concordance of increased B1 cell subset and lupus phenotypes in mice and humans is dependent on BLK expression levels.

Wu YY, Georg I, Díaz-Barreiro A, Varela N, Lauwerys B, Kumar R, Bagavant H, Castillo-Martín M, El Salem F, Marañón C, Alarcón-Riquelme ME.

J Immunol. 2015 Jun 15;194(12):5692-702. doi: 10.4049/jimmunol.1402736. Epub 2015 May 13.


Differential phenotypic and functional profiles of TcCA-2 -specific cytotoxic CD8+ T cells in the asymptomatic versus cardiac phase in Chagasic patients.

Egui A, Thomas MC, Carrilero B, Segovia M, Alonso C, Marañón C, López MC.

PLoS One. 2015 Mar 27;10(3):e0122115. doi: 10.1371/journal.pone.0122115. eCollection 2015.


The innate immune response status correlates with a divergent clinical course in congenital Chagas disease of twins born in a non-endemic country.

Fernández-Villegas A, Thomas MC, Carrilero B, Téllez C, Marañón C, Murcia L, Moralo S, Alonso C, Segovia M, López MC.

Acta Trop. 2014 Dec;140:84-90. doi: 10.1016/j.actatropica.2014.08.006. Epub 2014 Aug 19.


Apoptotic cell capture by DCs induces unexpectedly robust autologous CD4+ T-cell responses.

Valente M, Baey C, Louche P, Dutertre CA, Vimeux L, Marañón C, Hosmalin A, Feuillet V.

Eur J Immunol. 2014 Aug;44(8):2274-86. doi: 10.1002/eji.201344191. Epub 2014 Jun 11.


Benznidazole treatment reduces the induction of indoleamine 2,3-dioxygenase (IDO) enzymatic activity in Chagas disease symptomatic patients.

Marañón C, Egui A, Fernández-Villegas A, Carrilero B, Thomas MC, Segovia M, López MC.

Parasite Immunol. 2013 May-Jun;35(5-6):180-7. doi: 10.1111/pim.12030.


Trypanosoma cruzi paraflagellar rod proteins 2 and 3 contain immunodominant CD8(+) T-cell epitopes that are recognized by cytotoxic T cells from Chagas disease patients.

Egui A, Thomas MC, Morell M, Marañón C, Carrilero B, Segovia M, Puerta CJ, Pinazo MJ, Rosas F, Gascón J, López MC.

Mol Immunol. 2012 Oct;52(3-4):289-98. doi: 10.1016/j.molimm.2012.05.021. Epub 2012 Jun 29.


Kinetics of the interaction between anti-FVIII antibodies and FVIII from therapeutic concentrates, with and without von Willebrand factor, assessed by surface plasmon resonance.

Grancha S, Ortiz AM, Marañón C, Hampel K, Moret A, Zimmermann B, Jorquera JI, Aznar JA.

Haemophilia. 2012 Nov;18(6):982-9. doi: 10.1111/j.1365-2516.2012.02858.x. Epub 2012 May 30.


Characterization of an immunodominant antigenic epitope from Trypanosoma cruzi as a biomarker of chronic Chagas' disease pathology.

Thomas MC, Fernández-Villegas A, Carrilero B, Marañón C, Saura D, Noya O, Segovia M, Alarcón de Noya B, Alonso C, López MC.

Clin Vaccine Immunol. 2012 Feb;19(2):167-73. doi: 10.1128/CVI.05566-11. Epub 2011 Dec 7.


Short-term follow-up of chagasic patients after benzonidazole treatment using multiple serological markers.

Fernández-Villegas A, Pinazo MJ, Marañón C, Thomas MC, Posada E, Carrilero B, Segovia M, Gascon J, López MC.

BMC Infect Dis. 2011 Jul 31;11:206. doi: 10.1186/1471-2334-11-206.


Identification of HLA-A∗02:01-restricted CTL epitopes in Trypanosoma cruzi heat shock protein-70 recognized by Chagas disease patients.

Marañón C, Egui A, Carrilero B, Thomas MC, Pinazo MJ, Gascón J, Segovia M, López MC.

Microbes Infect. 2011 Nov;13(12-13):1025-32. doi: 10.1016/j.micinf.2011.05.010. Epub 2011 Jun 12.


Incomplete tyrosine 1680 sulphation in recombinant FVIII concentrates.

Grancha S, Navajas R, Marañón C, Paradela A, Albar JP, Jorquera JI.

Haemophilia. 2011 Jul;17(4):709-10. doi: 10.1111/j.1365-2516.2010.02454.x. Epub 2011 Feb 7. No abstract available.


Sublingual immunization with an HIV subunit vaccine induces antibodies and cytotoxic T cells in the mouse female genital tract.

Hervouet C, Luci C, Cuburu N, Cremel M, Bekri S, Vimeux L, Marañon C, Czerkinsky C, Hosmalin A, Anjuère F.

Vaccine. 2010 Aug 2;28(34):5582-90. doi: 10.1016/j.vaccine.2010.06.033. Epub 2010 Jun 25.


Cross-presentation by dendritic cells from live cells induces protective immune responses in vivo.

Matheoud D, Perié L, Hoeffel G, Vimeux L, Parent I, Marañón C, Bourdoncle P, Renia L, Prevost-Blondel A, Lucas B, Feuillet V, Hosmalin A.

Blood. 2010 Jun 3;115(22):4412-20. doi: 10.1182/blood-2009-11-255935. Epub 2010 Mar 22.


Antigen crosspresentation by human plasmacytoid dendritic cells.

Hoeffel G, Ripoche AC, Matheoud D, Nascimbeni M, Escriou N, Lebon P, Heshmati F, Guillet JG, Gannagé M, Caillat-Zucman S, Casartelli N, Schwartz O, De la Salle H, Hanau D, Hosmalin A, Marañón C.

Immunity. 2007 Sep;27(3):481-92.


CCR5 signaling through phospholipase D involves p44/42 MAP-kinases and promotes HIV-1 LTR-directed gene expression.

Paruch S, Heinis M, Lemay J, Hoeffel G, Marañón C, Hosmalin A, Périanin A.

FASEB J. 2007 Dec;21(14):4038-46. Epub 2007 Jul 12.


Do apoptotic Plasmodium-infected hepatocytes initiate protective immune responses?

Renia L, Maranon C, Hosmalin A, Gruner AC, Silvie O, Snounou G.

J Infect Dis. 2006 Jan 1;193(1):163-4; author reply 164-5. No abstract available.


Efficient stimulation of HIV-1-specific T cells using dendritic cells electroporated with mRNA encoding autologous HIV-1 Gag and Env proteins.

Van Gulck ER, Ponsaerts P, Heyndrickx L, Vereecken K, Moerman F, De Roo A, Colebunders R, Van den Bosch G, Van Bockstaele DR, Van Tendeloo VF, Allard S, Verrier B, Marañón C, Hoeffel G, Hosmalin A, Berneman ZN, Vanham G.

Blood. 2006 Mar 1;107(5):1818-27. Epub 2005 Nov 1.


Type I interferon production is profoundly and transiently impaired in primary HIV-1 infection.

Kamga I, Kahi S, Develioglu L, Lichtner M, Marañón C, Deveau C, Meyer L, Goujard C, Lebon P, Sinet M, Hosmalin A.

J Infect Dis. 2005 Jul 15;192(2):303-10. Epub 2005 Jun 15.


Dendritic cell precursors are permissive to dengue virus and human immunodeficiency virus infection.

Kwan WH, Helt AM, Marañón C, Barbaroux JB, Hosmalin A, Harris E, Fridman WH, Mueller CG.

J Virol. 2005 Jun;79(12):7291-9.

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