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Results: 18

1.

Sox2 as a servant of two masters.

Mankan AK, Hornung V.

Nat Immunol. 2015 Apr;16(4):335-6. doi: 10.1038/ni.3121. No abstract available.

PMID:
25789674
2.

Cytosolic RNA:DNA hybrids activate the cGAS-STING axis.

Mankan AK, Schmidt T, Chauhan D, Goldeck M, Höning K, Gaidt M, Kubarenko AV, Andreeva L, Hopfner KP, Hornung V.

EMBO J. 2014 Dec 17;33(24):2937-46. doi: 10.15252/embj.201488726. Epub 2014 Nov 25.

PMID:
25425575
3.

IKKα promotes intestinal tumorigenesis by limiting recruitment of M1-like polarized myeloid cells.

Göktuna SI, Canli O, Bollrath J, Fingerle AA, Horst D, Diamanti MA, Pallangyo C, Bennecke M, Nebelsiek T, Mankan AK, Lang R, Artis D, Hu Y, Patzelt T, Ruland J, Kirchner T, Taketo MM, Chariot A, Arkan MC, Greten FR.

Cell Rep. 2014 Jun 26;7(6):1914-25. doi: 10.1016/j.celrep.2014.05.006. Epub 2014 May 29.

4.

Retroviral danger from within: TLR7 is in control.

Mankan AK, Hornung V.

Immunity. 2012 Nov 16;37(5):763-6. doi: 10.1016/j.immuni.2012.10.009.

5.

Immunology in clinic review series; focus on autoinflammatory diseases: inflammasomes: mechanisms of activation.

Mankan AK, Kubarenko A, Hornung V.

Clin Exp Immunol. 2012 Mar;167(3):369-81. doi: 10.1111/j.1365-2249.2011.04534.x. Review.

6.

The NLRP3/ASC/Caspase-1 axis regulates IL-1β processing in neutrophils.

Mankan AK, Dau T, Jenne D, Hornung V.

Eur J Immunol. 2012 Mar;42(3):710-5. doi: 10.1002/eji.201141921. Epub 2012 Jan 19.

PMID:
22213227
7.

Inhibiting signal transducer and activator of transcription 3: rationality and rationale design of inhibitors.

Mankan AK, Greten FR.

Expert Opin Investig Drugs. 2011 Sep;20(9):1263-75. doi: 10.1517/13543784.2011.601739. Epub 2011 Jul 14. Review.

PMID:
21751940
8.

TNF-alpha-dependent loss of IKKbeta-deficient myeloid progenitors triggers a cytokine loop culminating in granulocytosis.

Mankan AK, Canli O, Schwitalla S, Ziegler P, Tschopp J, Korn T, Greten FR.

Proc Natl Acad Sci U S A. 2011 Apr 19;108(16):6567-72. doi: 10.1073/pnas.1018331108. Epub 2011 Apr 4.

9.

Highly sensitivity adhesion molecules detection in hereditary haemochromatosis patients reveals altered expression.

Norris S, White M, Mankan AK, Lawless MW.

Int J Immunogenet. 2010 Apr;37(2):125-33. doi: 10.1111/j.1744-313X.2010.00904.x. Epub 2010 Feb 19.

PMID:
20193033
10.

NF-kappaB regulation: the nuclear response.

Mankan AK, Lawless MW, Gray SG, Kelleher D, McManus R.

J Cell Mol Med. 2009 Apr;13(4):631-43. doi: 10.1111/j.1582-4934.2009.00632.x. Review.

11.

Characterization of tumour necrosis factor-alpha genetic variants and mRNA expression in patients with severe sepsis.

O'Dwyer MJ, Mankan AK, Ryan AW, Lawless MW, Stordeur P, Kelleher D, McManus R, Ryan T.

Int J Immunogenet. 2008 Aug;35(4-5):279-85. doi: 10.1111/j.1744-313X.2008.00773.x. Epub 2008 Jul 17.

PMID:
18643840
12.

Endoplasmic reticulum stress--a double edged sword for Z alpha-1 antitrypsin deficiency hepatoxicity.

Lawless MW, Mankan AK, Gray SG, Norris S.

Int J Biochem Cell Biol. 2008;40(8):1403-14. doi: 10.1016/j.biocel.2008.02.008. Epub 2008 Feb 16. Review.

PMID:
18353704
13.

The human response to infection is associated with distinct patterns of interleukin 23 and interleukin 27 expression.

O'Dwyer MJ, Mankan AK, White M, Lawless MW, Stordeur P, O'Connell B, Kelleher DP, McManus R, Ryan T.

Intensive Care Med. 2008 Apr;34(4):683-91. doi: 10.1007/s00134-007-0968-5. Epub 2008 Jan 29.

PMID:
18227999
14.

Tauroursodeoxycholic acid: relieving the pathogenesis of HFE C282Y hereditary hemochromatosis.

Lawless MW, Mankan AK, Ryan AW, Norris S.

Hepatology. 2008 Jul;48(1):344-5. doi: 10.1002/hep.22155. No abstract available.

PMID:
18203149
15.

Hereditary hemochromatosis should be considered a conformational disorder.

Lawless MW, Mankan AK, Norris S.

Med Hypotheses. 2008;70(4):783-4. Epub 2007 Sep 29.

PMID:
17904763
16.

Elevated MCP-1 serum levels are associated with the H63D mutation and not the C282Y mutation in hereditary hemochromatosis.

Lawless MW, White M, Mankan AK, O'Dwyer MJ, Norris S.

Tissue Antigens. 2007 Oct;70(4):294-300.

PMID:
17767550
17.
18.

The occurrence of severe sepsis and septic shock are related to distinct patterns of cytokine gene expression.

O'Dwyer MJ, Mankan AK, Stordeur P, O'Connell B, Duggan E, White M, Kelleher DP, McManus R, Ryan T.

Shock. 2006 Dec;26(6):544-50.

PMID:
17117127
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