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Results: 1 to 20 of 98

1.

A novel role for central ACBP/DBI as a regulator of long-chain fatty acid metabolism in astrocytes.

Bouyakdan K, Taïb B, Budry L, Zhao S, Rodaros D, Neess D, Mandrup S, Faergeman NJ, Alquier T.

J Neurochem. 2015 Jan 17. doi: 10.1111/jnc.13035. [Epub ahead of print]

PMID:
25598214
[PubMed - as supplied by publisher]
2.

iRNA-seq: computational method for genome-wide assessment of acute transcriptional regulation from total RNA-seq data.

Madsen JG, Schmidt SF, Larsen BD, Loft A, Nielsen R, Mandrup S.

Nucleic Acids Res. 2015 Jan 6. pii: gku1365. [Epub ahead of print]

PMID:
25564527
[PubMed - as supplied by publisher]
Free Article
3.

Browning of human adipocytes requires KLF11 and reprogramming of PPARγ superenhancers.

Loft A, Forss I, Siersbæk MS, Schmidt SF, Larsen AS, Madsen JG, Pisani DF, Nielsen R, Aagaard MM, Mathison A, Neville MJ, Urrutia R, Karpe F, Amri EZ, Mandrup S.

Genes Dev. 2015 Jan 1;29(1):7-22. doi: 10.1101/gad.250829.114. Epub 2014 Dec 12.

PMID:
25504365
[PubMed - in process]
4.

In memoriam: M. Daniel Lane, 1930-2014.

Mandrup S, MacDougald OA, Moss J, Ntambi J, Pekala P, Tang QQ, Wolfgang M, Bernlohr DA.

Trends Endocrinol Metab. 2014 Sep;25(9):437-9. doi: 10.1016/j.tem.2014.06.013. Epub 2014 Jul 29. No abstract available.

PMID:
25084731
[PubMed - in process]
5.

CD1d-mediated presentation of endogenous lipid antigens by adipocytes requires microsomal triglyceride transfer protein.

Rakhshandehroo M, Gijzel SM, Siersbæk R, Broekema MF, de Haar C, Schipper HS, Boes M, Mandrup S, Kalkhoven E.

J Biol Chem. 2014 Aug 8;289(32):22128-39. doi: 10.1074/jbc.M114.551242. Epub 2014 Jun 25.

PMID:
24966328
[PubMed - in process]
6.

Molecular architecture of transcription factor hotspots in early adipogenesis.

Siersbæk R, Baek S, Rabiee A, Nielsen R, Traynor S, Clark N, Sandelin A, Jensen ON, Sung MH, Hager GL, Mandrup S.

Cell Rep. 2014 Jun 12;7(5):1434-42. doi: 10.1016/j.celrep.2014.04.043. Epub 2014 May 22.

PMID:
24857666
[PubMed - in process]
Free Article
7.

Transcription factor cooperativity in early adipogenic hotspots and super-enhancers.

Siersbæk R, Rabiee A, Nielsen R, Sidoli S, Traynor S, Loft A, La Cour Poulsen L, Rogowska-Wrzesinska A, Jensen ON, Mandrup S.

Cell Rep. 2014 Jun 12;7(5):1443-55. doi: 10.1016/j.celrep.2014.04.042. Epub 2014 May 22.

PMID:
24857652
[PubMed - in process]
Free Article
8.

PPARγ and the global map of adipogenesis and beyond.

Lefterova MI, Haakonsson AK, Lazar MA, Mandrup S.

Trends Endocrinol Metab. 2014 Jun;25(6):293-302. doi: 10.1016/j.tem.2014.04.001. Epub 2014 Apr 29. Review.

PMID:
24793638
[PubMed - indexed for MEDLINE]
9.

Transcriptional and epigenetic mechanisms underlying enhanced in vitro adipocyte differentiation by the brominated flame retardant BDE-47.

Kamstra JH, Hruba E, Blumberg B, Janesick A, Mandrup S, Hamers T, Legler J.

Environ Sci Technol. 2014 Apr 1;48(7):4110-9. doi: 10.1021/es405524b. Epub 2014 Mar 11.

PMID:
24559133
[PubMed - indexed for MEDLINE]
10.

Genome-wide profiling of transcription factor binding and epigenetic marks in adipocytes by ChIP-seq.

Nielsen R, Mandrup S.

Methods Enzymol. 2014;537:261-79. doi: 10.1016/B978-0-12-411619-1.00014-8.

PMID:
24480351
[PubMed - indexed for MEDLINE]
11.

Lysine deacetylase inhibition prevents diabetes by chromatin-independent immunoregulation and β-cell protection.

Christensen DP, Gysemans C, Lundh M, Dahllöf MS, Noesgaard D, Schmidt SF, Mandrup S, Birkbak N, Workman CT, Piemonti L, Blaabjerg L, Monzani V, Fossati G, Mascagni P, Paraskevas S, Aikin RA, Billestrup N, Grunnet LG, Dinarello CA, Mathieu C, Mandrup-Poulsen T.

Proc Natl Acad Sci U S A. 2014 Jan 21;111(3):1055-9. doi: 10.1073/pnas.1320850111. Epub 2014 Jan 6.

PMID:
24395784
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Peroxisome proliferator-activated receptor γ and C/EBPα synergistically activate key metabolic adipocyte genes by assisted loading.

Madsen MS, Siersbæk R, Boergesen M, Nielsen R, Mandrup S.

Mol Cell Biol. 2014 Mar;34(6):939-54. doi: 10.1128/MCB.01344-13. Epub 2013 Dec 30.

PMID:
24379442
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Delayed hepatic adaptation to weaning in ACBP-/- mice is caused by disruption of the epidermal barrier.

Neess D, Bek S, Bloksgaard M, Marcher AB, Færgeman NJ, Mandrup S.

Cell Rep. 2013 Dec 12;5(5):1403-12. doi: 10.1016/j.celrep.2013.11.010. Epub 2013 Dec 5.

PMID:
24316079
[PubMed - indexed for MEDLINE]
Free Article
14.

Acyl-CoA binding protein and epidermal barrier function.

Bloksgaard M, Neess D, Færgeman NJ, Mandrup S.

Biochim Biophys Acta. 2014 Mar;1841(3):369-76. doi: 10.1016/j.bbalip.2013.09.013. Epub 2013 Sep 29.

PMID:
24080521
[PubMed - indexed for MEDLINE]
15.

Acute genome-wide effects of rosiglitazone on PPARγ transcriptional networks in adipocytes.

Haakonsson AK, Stahl Madsen M, Nielsen R, Sandelin A, Mandrup S.

Mol Endocrinol. 2013 Sep;27(9):1536-49. doi: 10.1210/me.2013-1080. Epub 2013 Jul 24.

PMID:
23885096
[PubMed - indexed for MEDLINE]
16.

Archived neonatal dried blood spot samples can be used for accurate whole genome and exome-targeted next-generation sequencing.

Hollegaard MV, Grauholm J, Nielsen R, Grove J, Mandrup S, Hougaard DM.

Mol Genet Metab. 2013 Sep-Oct;110(1-2):65-72. doi: 10.1016/j.ymgme.2013.06.004. Epub 2013 Jun 13.

PMID:
23830478
[PubMed - indexed for MEDLINE]
17.

Short-chain fatty acids stimulate angiopoietin-like 4 synthesis in human colon adenocarcinoma cells by activating peroxisome proliferator-activated receptor γ.

Alex S, Lange K, Amolo T, Grinstead JS, Haakonsson AK, Szalowska E, Koppen A, Mudde K, Haenen D, Al-Lahham S, Roelofsen H, Houtman R, van der Burg B, Mandrup S, Bonvin AM, Kalkhoven E, Müller M, Hooiveld GJ, Kersten S.

Mol Cell Biol. 2013 Apr;33(7):1303-16. doi: 10.1128/MCB.00858-12. Epub 2013 Jan 22.

PMID:
23339868
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Effects of short-term high-fat overfeeding on genome-wide DNA methylation in the skeletal muscle of healthy young men.

Jacobsen SC, Brøns C, Bork-Jensen J, Ribel-Madsen R, Yang B, Lara E, Hall E, Calvanese V, Nilsson E, Jørgensen SW, Mandrup S, Ling C, Fernandez AF, Fraga MF, Poulsen P, Vaag A.

Diabetologia. 2012 Dec;55(12):3341-9. doi: 10.1007/s00125-012-2717-8. Epub 2012 Sep 8.

PMID:
22961225
[PubMed - indexed for MEDLINE]
19.

The acyl-CoA binding protein is required for normal epidermal barrier function in mice.

Bloksgaard M, Bek S, Marcher AB, Neess D, Brewer J, Hannibal-Bach HK, Helledie T, Fenger C, Due M, Berzina Z, Neubert R, Chemnitz J, Finsen B, Clemmensen A, Wilbertz J, Saxtorph H, Knudsen J, Bagatolli L, Mandrup S.

J Lipid Res. 2012 Oct;53(10):2162-74. doi: 10.1194/jlr.M029553. Epub 2012 Jul 24.

PMID:
22829653
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Genome-wide profiling of peroxisome proliferator-activated receptor γ in primary epididymal, inguinal, and brown adipocytes reveals depot-selective binding correlated with gene expression.

Siersbæk MS, Loft A, Aagaard MM, Nielsen R, Schmidt SF, Petrovic N, Nedergaard J, Mandrup S.

Mol Cell Biol. 2012 Sep;32(17):3452-63. doi: 10.1128/MCB.00526-12. Epub 2012 Jun 25.

PMID:
22733994
[PubMed - indexed for MEDLINE]
Free PMC Article

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