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Effects of conventional immunosuppressive treatment on CD244+ (CD28null) and FOXP3+ T cells in the inflamed muscle of patients with polymyositis and dermatomyositis.

Pandya JM, Loell I, Hossain MS, Zong M, Alexanderson H, Raghavan S, Lundberg IE, Malmström V.

Arthritis Res Ther. 2016 Apr 1;18:80. doi: 10.1186/s13075-016-0974-5.


Late-onset neutropenia after rituximab in ANCA-associated vasculitis.

Knight A, Sundström Y, Börjesson O, Bruchfeld A, Malmström V, Gunnarsson I.

Scand J Rheumatol. 2016 Mar 7:1-4. [Epub ahead of print]


RA-relevant T cell responses to type II collagen can be influenced by post-translational modifications.

Chemin K, Pollastro S, Albrecht I, Holmdahl R, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 Mar 4. doi: 10.1002/art.39660. [Epub ahead of print] No abstract available.


CD4+ and CD8+ CD28null T cells are Cytotoxic to Autologous Muscle Cells in Polymyositis Patients.

Pandya JM, Venalis P, Al-Khalili L, Hossain MS, Stache V, Lundberg IE, Malmström V, Fasth AE.

Arthritis Rheumatol. 2016 Feb 19. doi: 10.1002/art.39650. [Epub ahead of print]


Is rheumatoid arthritis an autoimmune disease?

Chemin K, Klareskog L, Malmström V.

Curr Opin Rheumatol. 2016 Mar;28(2):181-8. doi: 10.1097/BOR.0000000000000253.


A Novel HLA-DRB1*10:01-Restricted T Cell Epitope From Citrullinated Type II Collagen Relevant to Rheumatoid Arthritis.

Chemin K, Pollastro S, James E, Ge C, Albrecht I, Herrath J, Gerstner C, Tandre K, Sampaio Rizzi T, Rönnblom L, Catrina A, Holmdahl R, Klareskog L, de Vries N, Malmström V.

Arthritis Rheumatol. 2016 May;68(5):1124-35. doi: 10.1002/art.39553.


Mechanisms involved in triggering rheumatoid arthritis.

Catrina AI, Joshua V, Klareskog L, Malmström V.

Immunol Rev. 2016 Jan;269(1):162-74. doi: 10.1111/imr.12379. Review.


Autoantibodies to citrullinated proteins induce joint pain independent of inflammation via a chemokine-dependent mechanism.

Wigerblad G, Bas DB, Fernades-Cerqueira C, Krishnamurthy A, Nandakumar KS, Rogoz K, Kato J, Sandor K, Su J, Jimenez-Andrade JM, Finn A, Bersellini Farinotti A, Amara K, Lundberg K, Holmdahl R, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Svensson CI.

Ann Rheum Dis. 2016 Apr;75(4):730-8. doi: 10.1136/annrheumdis-2015-208094. Epub 2015 Nov 27.


Identification of a novel chemokine-dependent molecular mechanism underlying rheumatoid arthritis-associated autoantibody-mediated bone loss.

Krishnamurthy A, Joshua V, Haj Hensvold A, Jin T, Sun M, Vivar N, Ytterberg AJ, Engström M, Fernandes-Cerqueira C, Amara K, Magnusson M, Wigerblad G, Kato J, Jiménez-Andrade JM, Tyson K, Rapecki S, Lundberg K, Catrina SB, Jakobsson PJ, Svensson C, Malmström V, Klareskog L, Wähämaa H, Catrina AI.

Ann Rheum Dis. 2016 Apr;75(4):721-9. doi: 10.1136/annrheumdis-2015-208093. Epub 2015 Nov 26.


IL-1R1 is expressed on both Helios(+) and Helios(-) FoxP3(+) CD4(+) T cells in the rheumatic joint.

Müller M, Herrath J, Malmström V.

Clin Exp Immunol. 2015 Oct;182(1):90-100. doi: 10.1111/cei.12668. Epub 2015 Jul 30.


IL-17 and IL-23 in lupus nephritis - association to histopathology and response to treatment.

Zickert A, Amoudruz P, Sundström Y, Rönnelid J, Malmström V, Gunnarsson I.

BMC Immunol. 2015 Feb 12;16:7. doi: 10.1186/s12865-015-0070-7.


Glycosylation of immunoglobulin G determines osteoclast differentiation and bone loss.

Harre U, Lang SC, Pfeifle R, Rombouts Y, Frühbeißer S, Amara K, Bang H, Lux A, Koeleman CA, Baum W, Dietel K, Gröhn F, Malmström V, Klareskog L, Krönke G, Kocijan R, Nimmerjahn F, Toes RE, Herrmann M, Scherer HU, Schett G.

Nat Commun. 2015 Mar 31;6:6651. doi: 10.1038/ncomms7651.


Evaluation of B lymphocyte stimulator and a proliferation inducing ligand as candidate biomarkers in lupus nephritis based on clinical and histopathological outcome following induction therapy.

Parodis I, Zickert A, Sundelin B, Axelsson M, Gerhardsson J, Svenungsson E, Malmström V, Gunnarsson I.

Lupus Sci Med. 2015 Jan 22;2(1):e000061. doi: 10.1136/lupus-2014-000061. eCollection 2015. Erratum in: Lupus Sci Med. 2015;2(1). pii: lupus-2014-000061corr1. doi: 10.1136/lupus-2014-000061corr1.


IgG antibodies to cyclic citrullinated peptides exhibit profiles specific in terms of IgG subclasses, Fc-glycans and a fab-Peptide sequence.

Lundström SL, Fernandes-Cerqueira C, Ytterberg AJ, Ossipova E, Hensvold AH, Jakobsson PJ, Malmström V, Catrina AI, Klareskog L, Lundberg K, Zubarev RA.

PLoS One. 2014 Nov 26;9(11):e113924. doi: 10.1371/journal.pone.0113924. eCollection 2014.


Expression of BAFF receptors in muscle tissue of myositis patients with anti-Jo-1 or anti-Ro52/anti-Ro60 autoantibodies.

Kryštůfková O, Barbasso Helmers S, Venalis P, Malmström V, Lindroos E, Vencovský J, Lundberg IE.

Arthritis Res Ther. 2014 Oct 10;16(5):454. doi: 10.1186/s13075-014-0454-8.


Accelerating translational research by clinically driven development of an informatics platform--a case study.

Abugessaisa I, Saevarsdottir S, Tsipras G, Lindblad S, Sandin C, Nikamo P, Ståhle M, Malmström V, Klareskog L, Tegnér J.

PLoS One. 2014 Sep 9;9(9):e104382. doi: 10.1371/journal.pone.0104382. eCollection 2014.


Non-HLA genes PTPN22, CDK6 and PADI4 are associated with specific autoantibodies in HLA-defined subgroups of rheumatoid arthritis.

Snir O, Gomez-Cabrero D, Montes A, Perez-Pampin E, Gómez-Reino JJ, Seddighzadeh M, Klich KU, Israelsson L, Ding B, Catrina AI, Holmdahl R, Alfredsson L, Klareskog L, Tegnér J, Gonzalez A, Malmström V, Padyukov L.

Arthritis Res Ther. 2014 Aug 20;16(4):414. doi: 10.1186/s13075-014-0414-3.


Affinity purified anti-citrullinated protein/peptide antibodies target antigens expressed in the rheumatoid joint.

Ossipova E, Cerqueira CF, Reed E, Kharlamova N, Israelsson L, Holmdahl R, Nandakumar KS, Engström M, Harre U, Schett G, Catrina AI, Malmström V, Sommarin Y, Klareskog L, Jakobsson PJ, Lundberg K.

Arthritis Res Ther. 2014 Aug 12;16(4):R167. doi: 10.1186/ar4683.


Lungs, joints and immunity against citrullinated proteins in rheumatoid arthritis.

Catrina AI, Ytterberg AJ, Reynisdottir G, Malmström V, Klareskog L.

Nat Rev Rheumatol. 2014 Nov;10(11):645-53. doi: 10.1038/nrrheum.2014.115. Epub 2014 Jul 29. Review.


Type II collagen antibody response is enriched in the synovial fluid of rheumatoid joints and directed to the same major epitopes as in collagen induced arthritis in primates and mice.

Lindh I, Snir O, Lönnblom E, Uysal H, Andersson I, Nandakumar KS, Vierboom M, 't Hart B, Malmström V, Holmdahl R.

Arthritis Res Ther. 2014 Jul 8;16(4):R143. doi: 10.1186/ar4605.

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