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Items: 1 to 20 of 240

1.

Transformation of human CD34+ hematopoietic progenitor cells with DEK-NUP214 induces AML in an immunocompromised mouse model.

Qin H, Malek S, Cowell JK, Ren M.

Oncogene. 2016 Apr 11. doi: 10.1038/onc.2016.118. [Epub ahead of print]

PMID:
27065320
2.

A Quantitative Analysis of Subclonal and Clonal Gene Mutations Pre- and Post-therapy in Chronic Lymphocytic Leukemia.

Amin N, Seymour EK, Saiya-Cork K, Parkin B, Shedden K, Malek S.

Clin Cancer Res. 2016 Apr 8. pii: clincanres.3103.2015. [Epub ahead of print]

PMID:
27060156
3.

Gene mutations in chronic lymphocytic leukemia.

Amin NA, Malek SN.

Semin Oncol. 2016 Apr;43(2):215-21. doi: 10.1053/j.seminoncol.2016.02.002. Epub 2016 Feb 6. Review.

PMID:
27040699
4.

Activation Mechanism of Oncogenic Deletion Mutations in BRAF, EGFR, and HER2.

Foster SA, Whalen DM, Özen A, Wongchenko MJ, Yin J, Yen I, Schaefer G, Mayfield JD, Chmielecki J, Stephens PJ, Albacker LA, Yan Y, Song K, Hatzivassiliou G, Eigenbrot C, Yu C, Shaw AS, Manning G, Skelton NJ, Hymowitz SG, Malek S.

Cancer Cell. 2016 Apr 11;29(4):477-93. doi: 10.1016/j.ccell.2016.02.010. Epub 2016 Mar 17.

PMID:
26996308
5.

Correction to Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.

Heald R, Bowman KK, Bryan MC, Burdick D, Chan B, Chan E, Chen Y, Clausen S, Dominguez-Fernandez B, Eigenbrot C, Elliott R, Hanan EJ, Jackson P, Knight J, La H, Lainchbury M, Malek S, Mann S, Merchant M, Mortara K, Purkey H, Schaefer G, Schmidt S, Seward E, Sideris S, Shao L, Wang S, Yeap K, Yen I, Yu C, Heffron TP.

J Med Chem. 2016 Mar 24;59(6):2848. doi: 10.1021/acs.jmedchem.6b00301. Epub 2016 Mar 11. No abstract available.

PMID:
26967667
6.

Non-aqueous extracts of Curcuma mangga rhizomes induced cell death in human colorectal adenocarcinoma cell line (HT29) via induction of apoptosis and cell cycle arrest at G0/G1 phase.

Hong GW, Hong SL, Lee GS, Yaacob H, Malek SN.

Asian Pac J Trop Med. 2016 Jan;9(1):8-18. doi: 10.1016/j.apjtm.2015.12.003. Epub 2015 Dec 19.

7.

Pyridones as Highly Selective, Noncovalent Inhibitors of T790M Double Mutants of EGFR.

Bryan MC, Burdick DJ, Chan BK, Chen Y, Clausen S, Dotson J, Eigenbrot C, Elliott R, Hanan EJ, Heald R, Jackson P, La H, Lainchbury M, Malek S, Mann SE, Purkey HE, Schaefer G, Schmidt S, Seward E, Sideris S, Wang S, Yen I, Yu C, Heffron TP.

ACS Med Chem Lett. 2015 Dec 17;7(1):100-4. doi: 10.1021/acsmedchemlett.5b00428. eCollection 2016 Jan 14.

PMID:
26819674
8.

Ferumoxytol-Enhanced Magnetic Resonance Imaging in Late-Stage CKD.

Mukundan S, Steigner ML, Hsiao LL, Malek SK, Tullius SG, Chin MS, Siedlecki AM.

Am J Kidney Dis. 2016 Jan 16. pii: S0272-6386(15)01498-5. doi: 10.1053/j.ajkd.2015.12.017. [Epub ahead of print]

PMID:
26786296
9.

Xanthohumol induces apoptosis and S phase cell cycle arrest in A549 non-small cell lung cancer cells.

Yong WK, Ho YF, Malek SN.

Pharmacogn Mag. 2015 Oct;11(Suppl 2):S275-83. doi: 10.4103/0973-1296.166069.

10.

4-Aminoindazolyl-dihydrofuro[3,4-d]pyrimidines as non-covalent inhibitors of mutant epidermal growth factor receptor tyrosine kinase.

Hanan EJ, Baumgardner M, Bryan MC, Chen Y, Eigenbrot C, Fan P, Gu XH, La H, Malek S, Purkey HE, Schaefer G, Schmidt S, Sideris S, Yen I, Yu C, Heffron TP.

Bioorg Med Chem Lett. 2016 Jan 15;26(2):534-9. doi: 10.1016/j.bmcl.2015.11.078. Epub 2015 Nov 22.

PMID:
26639762
11.

Noncovalent Mutant Selective Epidermal Growth Factor Receptor Inhibitors: A Lead Optimization Case Study.

Heald R, Bowman KK, Bryan MC, Burdick D, Chan B, Chan E, Chen Y, Clausen S, Dominguez-Fernandez B, Eigenbrot C, Elliott R, Hanan EJ, Jackson P, Knight J, La H, Lainchbury M, Malek S, Mann S, Merchant M, Mortara K, Purkey H, Schaefer G, Schmidt S, Seward E, Sideris S, Shao L, Wang S, Yeap K, Yen I, Yu C, Heffron TP.

J Med Chem. 2015 Nov 25;58(22):8877-95. doi: 10.1021/acs.jmedchem.5b01412. Epub 2015 Nov 12.

PMID:
26455919
12.

[Ten Cases of Cryptotia Corrected using Ono's Technique].

Meoli M, Malek S, Riml S, Grünert JG.

Handchir Mikrochir Plast Chir. 2015 Aug;47(4):242-5. doi: 10.1055/s-0035-1549918. Epub 2015 Aug 19. German.

PMID:
26287327
13.

Exploring the interaction between the antiallergic drug, tranilast and human serum albumin: Insights from calorimetric, spectroscopic and modeling studies.

Tayyab S, Zaroog MS, Feroz SR, Mohamad SB, Malek SN.

Int J Pharm. 2015 Aug 1;491(1-2):352-8. doi: 10.1016/j.ijpharm.2015.06.042. Epub 2015 Jun 30.

PMID:
26142245
14.

Menin-MLL inhibitors block oncogenic transformation by MLL-fusion proteins in a fusion partner-independent manner.

He S, Malik B, Borkin D, Miao H, Shukla S, Kempinska K, Purohit T, Wang J, Chen L, Parkin B, Malek SN, Danet-Desnoyers G, Muntean AG, Cierpicki T, Grembecka J.

Leukemia. 2016 Feb;30(2):508-13. doi: 10.1038/leu.2015.144. Epub 2015 Jun 18. No abstract available.

15.

Supramolecular interaction of 6-shogaol, a therapeutic agent of Zingiber officinale with human serum albumin as elucidated by spectroscopic, calorimetric and molecular docking methods.

Feroz SR, Mohamad SB, Lee GS, Malek SN, Tayyab S.

Phytomedicine. 2015 Jun 1;22(6):621-30. doi: 10.1016/j.phymed.2015.03.016. Epub 2015 Apr 9.

PMID:
26055127
16.

High-performance infrared light trapping in nano-needle structured p⁺ SnOx (x  ≤  1)/thin film n-Ge photodiodes on Si.

Wang X, Wong A, Malek S, Cai Y, Liu J.

Opt Lett. 2015 Jun 1;40(11):2603-6. doi: 10.1364/OL.40.002603.

PMID:
26030568
17.

Mitigation of Acetylcholine Esterase Activity in the 1,7-Diazacarbazole Series of Inhibitors of Checkpoint Kinase 1.

Gazzard L, Williams K, Chen H, Axford L, Blackwood E, Burton B, Chapman K, Crackett P, Drobnick J, Ellwood C, Epler J, Flagella M, Gancia E, Gill M, Goodacre S, Halladay J, Hewitt J, Hunt H, Kintz S, Lyssikatos J, Macleod C, Major S, Médard G, Narukulla R, Ramiscal J, Schmidt S, Seward E, Wiesmann C, Wu P, Yee S, Yen I, Malek S.

J Med Chem. 2015 Jun 25;58(12):5053-74. doi: 10.1021/acs.jmedchem.5b00464. Epub 2015 Jun 4.

PMID:
25988399
18.

A Quantum Chemical and Statistical Study of Cytotoxic Activity of Compounds Isolated from Curcuma zedoaria.

Hamdi OA, Anouar el H, Shilpi JA, Trabolsy ZB, Zain SB, Zakaria NS, Zulkefeli M, Weber JF, Malek SN, Rahman SN, Awang K.

Int J Mol Sci. 2015 Apr 27;16(5):9450-68. doi: 10.3390/ijms16059450.

19.

Ash1l controls quiescence and self-renewal potential in hematopoietic stem cells.

Jones M, Chase J, Brinkmeier M, Xu J, Weinberg DN, Schira J, Friedman A, Malek S, Grembecka J, Cierpicki T, Dou Y, Camper SA, Maillard I.

J Clin Invest. 2015 May;125(5):2007-20. doi: 10.1172/JCI78124. Epub 2015 Apr 13.

20.

Crystallization of Lennard-Jones nanodroplets: From near melting to deeply supercooled.

Malek SM, Morrow GP, Saika-Voivod I.

J Chem Phys. 2015 Mar 28;142(12):124506. doi: 10.1063/1.4915917.

PMID:
25833595
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