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Items: 1 to 20 of 108

1.

Quality of life, long-term survivors and long-term outcome from the ABC-02 study.

Bridgewater J, Lopes A, Palmer D, Cunningham D, Anthoney A, Maraveyas A, Madhusudan S, Iveson T, Valle J, Wasan H.

Br J Cancer. 2016 Apr 26;114(9):965-71. doi: 10.1038/bjc.2016.64.

PMID:
27115567
2.

Reply, Letter to the Editor - The impact of sarcopenia and myosteatosis on outcomes of unresectable pancreatic cancer or distal cholangiocarcinoma.

Rollins KE, Tewari N, Ackner A, Awwad A, Madhusudan S, Macdonald IA, Fearon KC, Lobo DN.

Clin Nutr. 2016 Jun;35(3):765-6. doi: 10.1016/j.clnu.2016.03.006. Epub 2016 Mar 17. No abstract available.

PMID:
27026511
3.

Human helicase RECQL4 drives cisplatin resistance in gastric cancer by activating an AKT-YB1-MDR1 signaling pathway.

Mo D, Fang H, Niu K, Liu J, Wu M, Li S, Zhu T, Aleskandarany MA, Arora A, Lobo DN, Madhusudan S, Balajee AS, Chi Z, Zhao Y.

Cancer Res. 2016 Mar 24. pii: canres.2361.2015. [Epub ahead of print]

PMID:
27013200
4.

Camptothecin targets WRN protein: mechanism and relevance in clinical breast cancer.

Shamanna RA, Lu H, Croteau DL, Arora A, Agarwal D, Ball G, Aleskandarany MA, Ellis IO, Pommier Y, Madhusudan S, Bohr VA.

Oncotarget. 2016 Mar 3. doi: 10.18632/oncotarget.7906. [Epub ahead of print]

5.

MYC functions are specific in biological subtypes of breast cancer and confers resistance to endocrine therapy in luminal tumours.

Green AR, Aleskandarany MA, Agarwal D, Elsheikh S, Nolan CC, Diez-Rodriguez M, Macmillan RD, Ball GR, Caldas C, Madhusudan S, Ellis IO, Rakha EA.

Br J Cancer. 2016 Apr 12;114(8):917-28. doi: 10.1038/bjc.2016.46. Epub 2016 Mar 8.

PMID:
26954716
6.

RECQL4 helicase has oncogenic potential in sporadic breast cancers.

Arora A, Agarwal D, Abdel-Fatah TM, Lu H, Croteau DL, Moseley P, Aleskandarany MA, Green AR, Ball G, Rakha EA, Chan SY, Ellis IO, Wang LL, Zhao Y, Balajee AS, Bohr VA, Madhusudan S.

J Pathol. 2016 Mar;238(4):495-501. doi: 10.1002/path.4681. Epub 2016 Feb 2.

PMID:
26690729
7.

ATM, ATR and DNA-PKcs expressions correlate to adverse clinical outcomes in epithelial ovarian cancers.

Abdel-Fatah TM, Arora A, Moseley P, Coveney C, Perry C, Johnson K, Kent C, Ball G, Chan S, Madhusudan S.

BBA Clin. 2014 Aug 14;2:10-7. doi: 10.1016/j.bbacli.2014.08.001. eCollection 2014 Dec.

8.

Clinicopathological and prognostic significance of RECQL5 helicase expression in breast cancers.

Arora A, Abdel-Fatah TM, Agarwal D, Doherty R, Croteau DL, Moseley PM, Hameed K, Green A, Aleskandarany MA, Rakha EA, Patterson K, Ball G, Chan SY, Ellis IO, Bohr VA, Bryant HE, Madhusudan S.

Carcinogenesis. 2016 Jan;37(1):63-71. doi: 10.1093/carcin/bgv163. Epub 2015 Nov 19.

PMID:
26586793
9.

Camptodactyly-arthropathy-coxa vara-pericarditis (CACP) syndrome: a mimicker of juvenile idiopathic arthritis.

Madhusudan S, Gupta A, Prakash M, Matta D, Suri D, Singh S.

Scand J Rheumatol. 2015 Oct 28:1-2. [Epub ahead of print] No abstract available.

PMID:
26508154
10.

Chk1 phosphorylated at serine(345) is a predictor of early local recurrence and radio-resistance in breast cancer.

Alsubhi N, Middleton F, Abdel-Fatah TM, Stephens P, Doherty R, Arora A, Moseley PM, Chan SY, Aleskandarany MA, Green AR, Rakha EA, Ellis IO, Martin SG, Curtin NJ, Madhusudan S.

Mol Oncol. 2016 Feb;10(2):213-23. doi: 10.1016/j.molonc.2015.09.009. Epub 2015 Oct 3.

PMID:
26459098
11.

The impact of sarcopenia and myosteatosis on outcomes of unresectable pancreatic cancer or distal cholangiocarcinoma.

Rollins KE, Tewari N, Ackner A, Awwad A, Madhusudan S, Macdonald IA, Fearon KC, Lobo DN.

Clin Nutr. 2015 Sep 1. pii: S0261-5614(15)00226-5. doi: 10.1016/j.clnu.2015.08.005. [Epub ahead of print]

PMID:
26411749
12.

5-Carboxylcytosine levels are elevated in human breast cancers and gliomas.

Eleftheriou M, Pascual AJ, Wheldon LM, Perry C, Abakir A, Arora A, Johnson AD, Auer DT, Ellis IO, Madhusudan S, Ruzov A.

Clin Epigenetics. 2015 Aug 21;7(1):88. doi: 10.1186/s13148-015-0117-x. eCollection 2015.

13.

DNA repair prognostic index modelling reveals an essential role for base excision repair in influencing clinical outcomes in ER negative and triple negative breast cancers.

Abdel-Fatah TM, Arora A, Moseley PM, Perry C, Rakha EA, Green AR, Chan SY, Ellis IO, Madhusudan S.

Oncotarget. 2015 Sep 8;6(26):21964-78.

14.

Cediranib or placebo in combination with cisplatin and gemcitabine chemotherapy for patients with advanced biliary tract cancer (ABC-03): a randomised phase 2 trial.

Valle JW, Wasan H, Lopes A, Backen AC, Palmer DH, Morris K, Duggan M, Cunningham D, Anthoney DA, Corrie P, Madhusudan S, Maraveyas A, Ross PJ, Waters JS, Steward WP, Rees C, Beare S, Dive C, Bridgewater JA.

Lancet Oncol. 2015 Aug;16(8):967-78. doi: 10.1016/S1470-2045(15)00139-4. Epub 2015 Jul 12. Erratum in: Lancet Oncol. 2015 Sep;16(9):e427.

15.

KPNA2 is a nuclear export protein that contributes to aberrant localisation of key proteins and poor prognosis of breast cancer.

Alshareeda AT, Negm OH, Green AR, Nolan CC, Tighe P, Albarakati N, Sultana R, Madhusudan S, Ellis IO, Rakha EA.

Br J Cancer. 2015 Jun 9;112(12):1929-37. doi: 10.1038/bjc.2015.165. Epub 2015 May 19.

16.

Transcriptomic profiling of Forkhead box transcription factors in adult glioblastoma multiforme.

Robertson E, Perry C, Doherty R, Madhusudan S.

Cancer Genomics Proteomics. 2015 May-Jun;12(3):103-12.

PMID:
25977169
17.

DNA Repair Endonucleases: Physiological Roles and Potential as Drug Targets.

Doherty R, Madhusudan S.

J Biomol Screen. 2015 Aug;20(7):829-41. doi: 10.1177/1087057115581581. Epub 2015 Apr 15. Review.

PMID:
25877151
18.

Monoclonal Antibodies Targeting LecLex-Related Glycans with Potent Antitumor Activity.

Chua JX, Vankemmelbeke M, McIntosh RS, Clarke PA, Moss R, Parsons T, Spendlove I, Zaitoun AM, Madhusudan S, Durrant LG.

Clin Cancer Res. 2015 Jul 1;21(13):2963-74. doi: 10.1158/1078-0432.CCR-14-3030. Epub 2015 Mar 16.

PMID:
25779947
19.

Checkpoint kinase1 (CHK1) is an important biomarker in breast cancer having a role in chemotherapy response.

Al-Kaabi MM, Alshareeda AT, Jerjees DA, Muftah AA, Green AR, Alsubhi NH, Nolan CC, Chan S, Cornford E, Madhusudan S, Ellis IO, Rakha EA.

Br J Cancer. 2015 Mar 3;112(5):901-11. doi: 10.1038/bjc.2014.576. Epub 2015 Feb 17.

20.

Transcriptomic and Protein Expression Analysis Reveals Clinicopathological Significance of Bloom Syndrome Helicase (BLM) in Breast Cancer.

Arora A, Abdel-Fatah TM, Agarwal D, Doherty R, Moseley PM, Aleskandarany MA, Green AR, Ball G, Alshareeda AT, Rakha EA, Chan SY, Ellis IO, Madhusudan S.

Mol Cancer Ther. 2015 Apr;14(4):1057-65. doi: 10.1158/1535-7163.MCT-14-0939. Epub 2015 Feb 11.

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