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Methods for Differentiating Prion Types in Food-Producing Animals.

Gough KC, Rees HC, Ives SE, Maddison BC.

Biology (Basel). 2015 Nov 13;4(4):785-813. Review.


Evidence for a novel Kit adhesion domain mediating human mast cell adhesion to structural airway cells.

Gough KC, Maddison BC, Shikotra A, Moiseeva EP, Yang W, Jarvis S, Bradding P.

Respir Res. 2015 Jul 15;16:86. doi: 10.1186/s12931-015-0245-z.


Does the Presence of Scrapie Affect the Ability of Current Statutory Discriminatory Tests To Detect the Presence of Bovine Spongiform Encephalopathy?

Simmons MM, Chaplin MJ, Vickery CM, Simon S, Davis L, Denyer M, Lockey R, Stack MJ, O'Connor MJ, Bishop K, Gough KC, Maddison BC, Thorne L, Spiropoulos J.

J Clin Microbiol. 2015 Aug;53(8):2593-604. doi: 10.1128/JCM.00508-15. Epub 2015 Jun 3.


Incubation of ovine scrapie with environmental matrix results in biological and biochemical changes of PrP(Sc) over time.

Maddison BC, Spiropoulos J, Vickery CM, Lockey R, Owen JP, Bishop K, Baker CA, Gough KC.

Vet Res. 2015 May 1;46:46. doi: 10.1186/s13567-015-0179-y.


Comparison of Schmallenberg virus antibody levels detected in milk and serum from individual cows.

Daly JM, King B, Tarlinton RA, Gough KC, Maddison BC, Blowey R.

BMC Vet Res. 2015 Mar 11;11:56. doi: 10.1186/s12917-015-0365-1.


Circulation of prions within dust on a scrapie affected farm.

Gough KC, Baker CA, Simmons HA, Hawkins SA, Maddison BC.

Vet Res. 2015 Apr 16;46:40. doi: 10.1186/s13567-015-0176-1.


Sensitive recovery of recombinant antibody clones after their in silico identification within NGS datasets.

Spiliotopoulos A, Owen JP, Maddison BC, Dreveny I, Rees HC, Gough KC.

J Immunol Methods. 2015 May;420:50-5. doi: 10.1016/j.jim.2015.03.005. Epub 2015 Mar 13.


The application of eDNA for monitoring of the Great Crested Newt in the UK.

Rees HC, Bishop K, Middleditch DJ, Patmore JR, Maddison BC, Gough KC.

Ecol Evol. 2014 Nov;4(21):4023-32. doi: 10.1002/ece3.1272. Epub 2014 Sep 30.


Persistence of ovine scrapie infectivity in a farm environment following cleaning and decontamination.

Hawkins SA, Simmons HA, Gough KC, Maddison BC.

Vet Rec. 2015 Jan 24;176(4):99. doi: 10.1136/vr.102743. Epub 2014 Oct 31.


In vitro amplification of ovine prions from scrapie-infected sheep from Great Britain reveals distinct patterns of propagation.

Thorne L, Holder T, Ramsay A, Edwards J, Taema MM, Windl O, Maddison BC, Gough KC, Terry LA.

BMC Vet Res. 2012 Nov 15;8:223. doi: 10.1186/1746-6148-8-223.


Temperature influences the interaction of ruminant PrP (TSE) with soil.

Maddison BC, Owen JP, Taema MM, Shaw G, Gough KC.

Prion. 2012 Jul 1;6(3):302-8. doi: 10.4161/pri.20025. Epub 2012 Jul 1.


The oral secretion of infectious scrapie prions occurs in preclinical sheep with a range of PRNP genotypes.

Gough KC, Baker CA, Rees HC, Terry LA, Spiropoulos J, Thorne L, Maddison BC.

J Virol. 2012 Jan;86(1):566-71. doi: 10.1128/JVI.05579-11. Epub 2011 Oct 19.


Differentiating ovine BSE from CH1641 scrapie by serial protein misfolding cyclic amplification.

Taema MM, Maddison BC, Thorne L, Bishop K, Owen J, Hunter N, Baker CA, Terry LA, Gough KC.

Mol Biotechnol. 2012 Jul;51(3):233-9. doi: 10.1007/s12033-011-9460-0.


Development of competitive immunoassays to hydroxyl containing fungicide metabolites.

Gough KC, Jarvis S, Maddison BC.

J Environ Sci Health B. 2011;46(7):581-9. doi: 10.1080/03601234.2011.586596.


Detection of prions in the faeces of sheep naturally infected with classical scrapie.

Terry LA, Howells L, Bishop K, Baker CA, Everest S, Thorne L, Maddison BC, Gough KC.

Vet Res. 2011 May 18;42:65. doi: 10.1186/1297-9716-42-65.


The interaction of ruminant PrP(Sc) with soils is influenced by prion source and soil type.

Maddison BC, Owen JP, Bishop K, Shaw G, Rees HC, Gough KC.

Environ Sci Technol. 2010 Nov 15;44(22):8503-8. doi: 10.1021/es101591a. Epub 2010 Oct 22.


Prion transmission: prion excretion and occurrence in the environment.

Gough KC, Maddison BC.

Prion. 2010 Oct-Dec;4(4):275-82. Epub 2010 Oct 17. Review.


Environmental sources of scrapie prions.

Maddison BC, Baker CA, Terry LA, Bellworthy SJ, Thorne L, Rees HC, Gough KC.

J Virol. 2010 Nov;84(21):11560-2. doi: 10.1128/JVI.01133-10. Epub 2010 Aug 25.


Risk of escape of prions in gaseous emissions from on-farm digestion vessels.

Adkin A, Matthews D, Hope J, Maddison BC, Somerville RA, Pedersen J.

Vet Rec. 2010 Jul 3;167(1):28-9. doi: 10.1136/vr.c3158. No abstract available.

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