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Systematic Review and Meta-Analysis of the Efficacy of Interleukin-1 Receptor Antagonist in Animal Models of Stroke: an Update.

McCann SK, Cramond F, Macleod MR, Sena ES.

Transl Stroke Res. 2016 Aug 15. [Epub ahead of print]


The Efficacy of Trastuzumab in Animal Models of Breast Cancer: A Systematic Review and Meta-Analysis.

Chen J, Yang C, Guo B, Sena ES, Macleod MR, Yuan Y, Hirst TC.

PLoS One. 2016 Jul 27;11(7):e0158240. doi: 10.1371/journal.pone.0158240. eCollection 2016.


A proposed framework for the systematic review and integrated assessment (SYRINA) of endocrine disrupting chemicals.

Vandenberg LN, Ågerstrand M, Beronius A, Beausoleil C, Bergman Å, Bero LA, Bornehag CG, Boyer CS, Cooper GS, Cotgreave I, Gee D, Grandjean P, Guyton KZ, Hass U, Heindel JJ, Jobling S, Kidd KA, Kortenkamp A, Macleod MR, Martin OV, Norinder U, Scheringer M, Thayer KA, Toppari J, Whaley P, Woodruff TJ, Rudén C.

Environ Health. 2016 Jul 14;15(1):74. doi: 10.1186/s12940-016-0156-6.


Olfactory Ensheathing Cell Transplantation in Experimental Spinal Cord Injury: Effect size and Reporting Bias of 62 Experimental Treatments: A Systematic Review and Meta-Analysis.

Watzlawick R, Rind J, Sena ES, Brommer B, Zhang T, Kopp MA, Dirnagl U, Macleod MR, Howells DW, Schwab JM.

PLoS Biol. 2016 May 31;14(5):e1002468. doi: 10.1371/journal.pbio.1002468. eCollection 2016 May.


Cardiac Stem Cell Treatment in Myocardial Infarction: A Systematic Review and Meta-Analysis of Preclinical Studies.

Zwetsloot PP, Végh AM, Jansen of Lorkeers SJ, van Hout GP, Currie GL, Sena ES, Gremmels H, Buikema JW, Goumans MJ, Macleod MR, Doevendans PA, Chamuleau SA, Sluijter JP.

Circ Res. 2016 Apr 15;118(8):1223-32. doi: 10.1161/CIRCRESAHA.115.307676. Epub 2016 Feb 17.


Correction: Risk of Bias in Reports of In Vivo Research: A Focus for Improvement.

Macleod MR, Lawson McLean A, Kyriakopoulou A, Serghiou S, de Wilde A, Sherratt N, Hirst T, Hemblade R, Bahor Z, Nunes-Fonseca C, Potluru A, Thomson A, Baginskaite J, Egan K, Vesterinen H, Currie GL, Churilov L, Howells DW, Sena ES.

PLoS Biol. 2015 Nov 10;13(11):e1002301. doi: 10.1371/journal.pbio.1002301. eCollection 2015 Nov.


Translational failure of anti-inflammatory compounds for myocardial infarction: a meta-analysis of large animal models.

van Hout GP, Jansen of Lorkeers SJ, Wever KE, Sena ES, Kouwenberg LH, van Solinge WW, Macleod MR, Doevendans PA, Pasterkamp G, Chamuleau SA, Hoefer IE.

Cardiovasc Res. 2016 Feb 1;109(2):240-8. doi: 10.1093/cvr/cvv239. Epub 2015 Oct 20.


Risk of Bias in Reports of In Vivo Research: A Focus for Improvement.

Macleod MR, Lawson McLean A, Kyriakopoulou A, Serghiou S, de Wilde A, Sherratt N, Hirst T, Hemblade R, Bahor Z, Nunes-Fonseca C, Potluru A, Thomson A, Baginskaite J, Egan K, Vesterinen H, Currie GL, Churilov L, Howells DW, Sena ES.

PLoS Biol. 2015 Oct 13;13(10):e1002273. doi: 10.1371/journal.pbio.1002273. eCollection 2015 Oct. Erratum in: PLoS Biol. 2015 Nov;13(11):e1002301. Baginskitae, Julija [corrected to Baginskaite, Julija].


Interventions for post-stroke fatigue.

Wu S, Kutlubaev MA, Chun HY, Cowey E, Pollock A, Macleod MR, Dennis M, Keane E, Sharpe M, Mead GE.

Cochrane Database Syst Rev. 2015 Jul 2;(7):CD007030. doi: 10.1002/14651858.CD007030.pub3. Review.


Increasing value and reducing waste in animal models of rheumatological disease.

Currie GL, Macleod MR.

Int J Rheum Dis. 2015 Jun;18(5):485-7. doi: 10.1111/1756-185X.12703. No abstract available.


Effect of endothelin receptor antagonists on clinically relevant outcomes after experimental subarachnoid hemorrhage: a systematic review and meta-analysis.

Laban KG, Vergouwen MD, Dijkhuizen RM, Sena ES, Macleod MR, Rinkel GJ, van der Worp HB.

J Cereb Blood Flow Metab. 2015 Jul;35(7):1085-9. doi: 10.1038/jcbfm.2015.89. Epub 2015 May 6. Review.


Drug repurposing: a systematic approach to evaluate candidate oral neuroprotective interventions for secondary progressive multiple sclerosis.

Vesterinen HM, Connick P, Irvine CM, Sena ES, Egan KJ, Carmichael GG, Tariq A, Pavitt S, Chataway J, Macleod MR, Chandran S.

PLoS One. 2015 Apr 9;10(4):e0117705. doi: 10.1371/journal.pone.0117705. eCollection 2015.


Magnetic resonance imaging in experimental stroke and comparison with histology: systematic review and meta-analysis.

Milidonis X, Marshall I, Macleod MR, Sena ES.

Stroke. 2015 Mar;46(3):843-51. doi: 10.1161/STROKEAHA.114.007560. Epub 2015 Feb 5. Review.


Incidence, prevalence, and predictors of chemotherapy-induced peripheral neuropathy: A systematic review and meta-analysis.

Seretny M, Currie GL, Sena ES, Ramnarine S, Grant R, MacLeod MR, Colvin LA, Fallon M.

Pain. 2014 Dec;155(12):2461-70. doi: 10.1016/j.pain.2014.09.020. Epub 2014 Sep 23. Review.


Similar effect of autologous and allogeneic cell therapy for ischemic heart disease: systematic review and meta-analysis of large animal studies.

Jansen Of Lorkeers SJ, Eding JE, Vesterinen HM, van der Spoel TI, Sena ES, Duckers HJ, Doevendans PA, Macleod MR, Chamuleau SA.

Circ Res. 2015 Jan 2;116(1):80-6. doi: 10.1161/CIRCRESAHA.116.304872. Epub 2014 Sep 3. Review.


Efficacy of antidepressants in animal models of ischemic stroke: a systematic review and meta-analysis.

McCann SK, Irvine C, Mead GE, Sena ES, Currie GL, Egan KE, Macleod MR, Howells DW.

Stroke. 2014 Oct;45(10):3055-63. doi: 10.1161/STROKEAHA.114.006304. Epub 2014 Sep 2. Review.


Preclinical research: Design animal studies better.

Macleod MR.

Nature. 2014 Jun 5;510(7503):35. doi: 10.1038/510035a. No abstract available.


EuroHYP-1: European multicenter, randomized, phase III clinical trial of therapeutic hypothermia plus best medical treatment vs. best medical treatment alone for acute ischemic stroke.

van der Worp HB, Macleod MR, Bath PM, Demotes J, Durand-Zaleski I, Gebhardt B, Gluud C, Kollmar R, Krieger DW, Lees KR, Molina C, Montaner J, Roine RO, Petersson J, Staykov D, Szabo I, Wardlaw JM, Schwab S; EuroHYP-1 investigators.

Int J Stroke. 2014 Jul;9(5):642-5. doi: 10.1111/ijs.12294. Epub 2014 May 15.


Using animal models to understand cancer pain in humans.

Currie GL, Sena ES, Fallon MT, Macleod MR, Colvin LA.

Curr Pain Headache Rep. 2014 Jun;18(6):423. doi: 10.1007/s11916-014-0423-6. Review.


End-of-life decisions in patients with severe acute brain injury.

Geurts M, Macleod MR, van Thiel GJ, van Gijn J, Kappelle LJ, van der Worp HB.

Lancet Neurol. 2014 May;13(5):515-24. doi: 10.1016/S1474-4422(14)70030-4. Epub 2014 Mar 25. Review.

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