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Results: 1 to 20 of 124

1.

Evidence of changes to skeletal muscle contractile properties during the initiation of disease in the ageing guinea pig model of osteoarthritis.

Tonge DP, Bardsley RG, Parr T, Maciewicz RA, Jones SW.

Longev Healthspan. 2013 Dec 1;2(1):15. doi: 10.1186/2046-2395-2-15.

PMID:
24472412
[PubMed]
2.

The association between ANKH promoter polymorphism and chondrocalcinosis is independent of age and osteoarthritis: results of a case-control study.

Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M, Valdes AM.

Arthritis Res Ther. 2014 Jan 27;16(1):R25. doi: 10.1186/ar4453.

PMID:
24467728
[PubMed - in process]
Free PMC Article
3.

Use of statins is associated with a lower prevalence of generalised osteoarthritis.

Valdes AM, Zhang W, Muir K, Maciewicz RA, Doherty S, Doherty M.

Ann Rheum Dis. 2014 May;73(5):943-5. doi: 10.1136/annrheumdis-2013-204382. Epub 2013 Dec 17. No abstract available.

PMID:
24347568
[PubMed - indexed for MEDLINE]
Free PMC Article
4.

The effect of FTO variation on increased osteoarthritis risk is mediated through body mass index: a mendelian randomisation study.

Panoutsopoulou K, Metrustry S, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, Zhang W, Muir KR, Wheeler M, Cooper C, Spector TD, Cicuttini FM, Jones G, Arden NK, Doherty M, Zeggini E, Valdes AM; arcOGEN Consortium.

Ann Rheum Dis. 2013 Aug 6. doi: 10.1136/annrheumdis-2013-203772. [Epub ahead of print]

PMID:
23921993
[PubMed - as supplied by publisher]
Free Article
5.

Association between low cortical bone mineral density, soft-tissue calcification, vascular calcification and chondrocalcinosis: a case-control study.

Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M.

Ann Rheum Dis. 2013 Aug 2. doi: 10.1136/annrheumdis-2013-203400. [Epub ahead of print]

PMID:
23912799
[PubMed - as supplied by publisher]
6.

Contribution of the COMT Val158Met variant to symptomatic knee osteoarthritis.

Neogi T, Soni A, Doherty SA, Laslett LL, Maciewicz RA, Hart DJ, Zhang W, Muir KR, Wheeler M, Cooper C, Spector TD, Cicuttini F, Jones G, Nevitt M, Liu Y, Arden NK, Doherty M, Valdes AM.

Ann Rheum Dis. 2014 Jan;73(1):315-7. doi: 10.1136/annrheumdis-2013-203836. Epub 2013 Jul 13. No abstract available.

PMID:
23852765
[PubMed - indexed for MEDLINE]
7.

Hydantoin based inhibitors of MMP13--discovery of AZD6605.

De Savi C, Waterson D, Pape A, Lamont S, Hadley E, Mills M, Page KM, Bowyer J, Maciewicz RA.

Bioorg Med Chem Lett. 2013 Aug 15;23(16):4705-12. doi: 10.1016/j.bmcl.2013.05.089. Epub 2013 Jun 10.

PMID:
23810497
[PubMed - indexed for MEDLINE]
8.

Gene-environment interaction between body mass index and transforming growth factor beta 1 (TGFβ1) gene in knee and hip osteoarthritis.

Muthuri SG, Doherty S, Zhang W, Maciewicz RA, Muir KR, Doherty M.

Arthritis Res Ther. 2013 Apr 18;15(2):R52. doi: 10.1186/ar4214.

PMID:
23597094
[PubMed - in process]
Free PMC Article
9.

The genetic contribution to severe post-traumatic osteoarthritis.

Valdes AM, Doherty SA, Muir KR, Wheeler M, Maciewicz RA, Zhang W, Doherty M.

Ann Rheum Dis. 2013 Oct;72(10):1687-90. doi: 10.1136/annrheumdis-2012-202562. Epub 2013 Jan 26.

PMID:
23355107
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

Evidence of a systemic predisposition to chondrocalcinosis and association between chondrocalcinosis and osteoarthritis at distant joints: a cross-sectional study.

Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M.

Arthritis Care Res (Hoboken). 2013 Jul;65(7):1052-8. doi: 10.1002/acr.21952.

PMID:
23335553
[PubMed - indexed for MEDLINE]
11.

Chondrocalcinosis is common in the absence of knee involvement.

Abhishek A, Doherty S, Maciewicz R, Muir K, Zhang W, Doherty M.

Arthritis Res Ther. 2012 Oct 4;14(5):R205. doi: 10.1186/ar4043.

PMID:
23036436
[PubMed - in process]
Free PMC Article
12.

Genetic contribution to radiographic severity in osteoarthritis of the knee.

Valdes AM, Doherty S, Muir KR, Zhang W, Maciewicz RA, Wheeler M, Arden N, Cooper C, Doherty M.

Ann Rheum Dis. 2012 Sep;71(9):1537-40. doi: 10.1136/annrheumdis-2012-201382. Epub 2012 May 21.

PMID:
22615457
[PubMed - indexed for MEDLINE]
Free PMC Article
13.

Genome-wide association and functional studies identify the DOT1L gene to be involved in cartilage thickness and hip osteoarthritis.

Castaño Betancourt MC, Cailotto F, Kerkhof HJ, Cornelis FM, Doherty SA, Hart DJ, Hofman A, Luyten FP, Maciewicz RA, Mangino M, Metrustry S, Muir K, Peters MJ, Rivadeneira F, Wheeler M, Zhang W, Arden N, Spector TD, Uitterlinden AG, Doherty M, Lories RJ, Valdes AM, van Meurs JB.

Proc Natl Acad Sci U S A. 2012 May 22;109(21):8218-23. doi: 10.1073/pnas.1119899109. Epub 2012 May 7.

PMID:
22566624
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

A role for PACE4 in osteoarthritis pain: evidence from human genetic association and null mutant phenotype.

Malfait AM, Seymour AB, Gao F, Tortorella MD, Le Graverand-Gastineau MP, Wood LS, Doherty M, Doherty S, Zhang W, Arden NK, Vaughn FL, Leaverton PE, Spector TD, Hart DJ, Maciewicz RA, Muir KR, Das R, Sorge RE, Sotocinal SG, Schorscher-Petcu A, Valdes AM, Mogil JS.

Ann Rheum Dis. 2012 Jun;71(6):1042-8. doi: 10.1136/annrheumdis-2011-200300. Epub 2012 Mar 22.

PMID:
22440827
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Mapping pathogenesis of arthritis through small animal models.

Vincent TL, Williams RO, Maciewicz R, Silman A, Garside P; Arthritis Research UK animal models working group.

Rheumatology (Oxford). 2012 Nov;51(11):1931-41. doi: 10.1093/rheumatology/kes035. Epub 2012 Mar 16. Review.

PMID:
22427408
[PubMed - indexed for MEDLINE]
16.

Distribution of finger nodes and their association with underlying radiographic features of osteoarthritis.

Rees F, Doherty S, Hui M, Maciewicz R, Muir K, Zhang W, Doherty M.

Arthritis Care Res (Hoboken). 2012 Apr;64(4):533-8. doi: 10.1002/acr.21586.

PMID:
22213746
[PubMed - indexed for MEDLINE]
17.

Self-reported knee malalignment in early adult life as an independent risk for knee chondrocalcinosis.

Abhishek A, Doherty S, Maciewicz RA, Muir KR, Zhang W, Doherty M.

Arthritis Care Res (Hoboken). 2011 Nov;63(11):1550-7. doi: 10.1002/acr.20593.

PMID:
22034117
[PubMed - indexed for MEDLINE]
18.

A variant in MCF2L is associated with osteoarthritis.

Day-Williams AG, Southam L, Panoutsopoulou K, Rayner NW, Esko T, Estrada K, Helgadottir HT, Hofman A, Ingvarsson T, Jonsson H, Keis A, Kerkhof HJ, Thorleifsson G, Arden NK, Carr A, Chapman K, Deloukas P, Loughlin J, McCaskie A, Ollier WE, Ralston SH, Spector TD, Wallis GA, Wilkinson JM, Aslam N, Birell F, Carluke I, Joseph J, Rai A, Reed M, Walker K; arcOGEN Consortium, Doherty SA, Jonsdottir I, Maciewicz RA, Muir KR, Metspalu A, Rivadeneira F, Stefansson K, Styrkarsdottir U, Uitterlinden AG, van Meurs JB, Zhang W, Valdes AM, Doherty M, Zeggini E.

Am J Hum Genet. 2011 Sep 9;89(3):446-50. doi: 10.1016/j.ajhg.2011.08.001. Epub 2011 Aug 25.

PMID:
21871595
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Inverse relationship between preoperative radiographic severity and postoperative pain in patients with osteoarthritis who have undergone total joint arthroplasty.

Valdes AM, Doherty SA, Zhang W, Muir KR, Maciewicz RA, Doherty M.

Semin Arthritis Rheum. 2012 Feb;41(4):568-75. doi: 10.1016/j.semarthrit.2011.07.002. Epub 2011 Aug 24.

PMID:
21868060
[PubMed - indexed for MEDLINE]
20.

Large scale replication study of the association between HLA class II/BTNL2 variants and osteoarthritis of the knee in European-descent populations.

Valdes AM, Styrkarsdottir U, Doherty M, Morris DL, Mangino M, Tamm A, Doherty SA, Kisand K, Kerna I, Tamm A, Wheeler M, Maciewicz RA, Zhang W, Muir KR, Dennison EM, Hart DJ, Metrustry S, Jonsdottir I, Jonsson GF, Jonsson H, Ingvarsson T, Cooper C, Vyse TJ, Spector TD, Stefansson K, Arden NK.

PLoS One. 2011;6(8):e23371. doi: 10.1371/journal.pone.0023371. Epub 2011 Aug 10.

PMID:
21853121
[PubMed - indexed for MEDLINE]
Free PMC Article

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