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Results: 1 to 20 of 360

1.

Mode of action and pharmacogenomic biomarkers for exceptional responders to didemnin B.

Potts MB, McMillan EA, Rosales TI, Kim HS, Ou YH, Toombs JE, Brekken RA, Minden MD, MacMillan JB, White MA.

Nat Chem Biol. 2015 Apr 13. doi: 10.1038/nchembio.1797. [Epub ahead of print]

PMID:
25867045
2.

Structural and Mechanistic Roles of Novel Chemical Ligands on the SdiA Quorum-Sensing Transcription Regulator.

Nguyen Y, Nguyen NX, Rogers JL, Liao J, MacMillan JB, Jiang Y, Sperandio V.

MBio. 2015 Mar 31;6(2). pii: e02429-14. doi: 10.1128/mBio.02429-14.

3.

Thiasporines A-C, Thiazine and Thiazole Derivatives from a Marine-Derived Actinomycetospora chlora.

Fu P, MacMillan JB.

J Nat Prod. 2015 Mar 27;78(3):548-51. doi: 10.1021/np500929z. Epub 2015 Jan 13.

PMID:
25584783
4.

Novel Mutations in the DYNC1H1 Tail Domain Refine the Genetic and Clinical Spectrum of Dyneinopathies.

Peeters K, Bervoets S, Chamova T, Litvinenko I, De Vriendt E, Bichev S, Kancheva D, Mitev V, Kennerson M, Timmerman V, De Jonghe P, Tournev I, MacMillan J, Jordanova A.

Hum Mutat. 2015 Mar;36(3):287-91. doi: 10.1002/humu.22744.

PMID:
25512093
5.

Inducamides A-C, chlorinated alkaloids from an RNA polymerase mutant strain of Streptomyces sp.

Fu P, Jamison M, La S, MacMillan JB.

Org Lett. 2014 Nov 7;16(21):5656-9. doi: 10.1021/ol502731p. Epub 2014 Oct 22.

PMID:
25338006
6.

Serum amyloid A is a retinol binding protein that transports retinol during bacterial infection.

Derebe MG, Zlatkov CM, Gattu S, Ruhn KA, Vaishnava S, Diehl GE, MacMillan JB, Williams NS, Hooper LV.

Elife. 2014 Jul 29;3:e03206. doi: 10.7554/eLife.03206.

7.

To fast or feed: an alternative life history for anadromous brook trout Salvelinus fontinalis overwintering within a harbour.

Spares AD, Dadswell MJ, MacMillan J, Madden R, O'Dor RK, Stokesbury MJ.

J Fish Biol. 2014 Sep;85(3):621-44. doi: 10.1111/jfb.12447. Epub 2014 Jun 24.

PMID:
24961666
8.

Carpatamides A-C, cytotoxic arylamine derivatives from a marine-derived Streptomyces sp.

Fu P, Johnson M, Chen H, Posner BA, MacMillan JB.

J Nat Prod. 2014 May 23;77(5):1245-8. doi: 10.1021/np500207p. Epub 2014 Apr 23.

PMID:
24754815
9.

Huntington disease: who seeks presymptomatic genetic testing, why and what are the outcomes?

Scuffham TM, MacMillan JC.

J Genet Couns. 2014 Oct;23(5):754-61. doi: 10.1007/s10897-013-9678-z. Epub 2014 Jan 8.

PMID:
24399092
10.

Using functional signature ontology (FUSION) to identify mechanisms of action for natural products.

Potts MB, Kim HS, Fisher KW, Hu Y, Carrasco YP, Bulut GB, Ou YH, Herrera-Herrera ML, Cubillos F, Mendiratta S, Xiao G, Hofree M, Ideker T, Xie Y, Huang LJ, Lewis RE, MacMillan JB, White MA.

Sci Signal. 2013 Oct 15;6(297):ra90. doi: 10.1126/scisignal.2004657.

11.

Discoipyrroles A-D: isolation, structure determination, and synthesis of potent migration inhibitors from Bacillus hunanensis.

Hu Y, Potts MB, Colosimo D, Herrera-Herrera ML, Legako AG, Yousufuddin M, White MA, MacMillan JB.

J Am Chem Soc. 2013 Sep 11;135(36):13387-92. doi: 10.1021/ja403412y. Epub 2013 Aug 28.

12.

Straight-talking education.

Macmillan JS.

Nurs Stand. 2013 Jun 5-11;27(40):64. No abstract available.

PMID:
23909185
13.

Towards bioavailability-based soil criteria: past, present and future perspectives.

Naidu R, Channey R, McConnell S, Johnston N, Semple KT, McGrath S, Dries V, Nathanail P, Harmsen J, Pruszinski A, Macmillan J, Palanisami T.

Environ Sci Pollut Res Int. 2013 Mar 22. [Epub ahead of print]

PMID:
23519481
14.
15.

Development of inhibitors of the PAS-B domain of the HIF-2α transcription factor.

Rogers JL, Bayeh L, Scheuermann TH, Longgood J, Key J, Naidoo J, Melito L, Shokri C, Frantz DE, Bruick RK, Gardner KH, MacMillan JB, Tambar UK.

J Med Chem. 2013 Feb 28;56(4):1739-47. doi: 10.1021/jm301847z. Epub 2013 Feb 18.

16.

Hunanamycin A, an antibiotic from a marine-derived Bacillus hunanensis.

Hu Y, Wang K, MacMillan JB.

Org Lett. 2013 Jan 18;15(2):390-3. doi: 10.1021/ol303376c. Epub 2013 Jan 10.

PMID:
23305153
17.

Nuclear export inhibition through covalent conjugation and hydrolysis of Leptomycin B by CRM1.

Sun Q, Carrasco YP, Hu Y, Guo X, Mirzaei H, Macmillan J, Chook YM.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):1303-8. doi: 10.1073/pnas.1217203110. Epub 2013 Jan 7.

18.

Precursor-Directed Generation of Amidine Containing Ammosamide Analogs: Ammosamides E-P.

Pan E, Oswald NW, Legako AG, Life JM, Posner BA, Macmillan JB.

Chem Sci. 2013 Jan;4(1):482-488.

19.

Anthraquinones from a marine-derived Streptomyces spinoverrucosus.

Hu Y, Martinez ED, MacMillan JB.

J Nat Prod. 2012 Oct 26;75(10):1759-64. doi: 10.1021/np3004326. Epub 2012 Oct 11.

20.

A labeled substrate approach to discovery of biocatalytic reactions: a proof of concept transformation with N-methylindole.

Rogers JL, MacMillan JB.

J Am Chem Soc. 2012 Aug 1;134(30):12378-81. doi: 10.1021/ja304767m. Epub 2012 Jul 18.

PMID:
22809085
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