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Results: 1 to 20 of 239

1.

BCL6 - regulated by AhR/ARNT and wild-type MEF2B - drives expression of germinal center markers MYBL1 and LMO2.

Ding J, Dirks WG, Ehrentraut S, Geffers R, MacLeod RA, Nagel S, Pommerenke C, Romani J, Scherr M, Vaas LA, Zaborski M, Drexler HG, Quentmeier H.

Haematologica. 2015 Mar 13. pii: haematol.2014.120048. [Epub ahead of print]

PMID:
25769544
Free Article
2.

High frequency of cryptic chromosomal rearrangements involving the LMO2 gene in T-cell acute lymphoblastic leukemia.

Wu L, Xu Y, Wang Q, Ruan C, Drexler HG, Wu D, MacLeod RA, Chen S.

Haematologica. 2015 Feb 14. pii: haematol.2014.120089. [Epub ahead of print]

3.

Malignant hematopoietic cell lines: in vitro models for the study of primary mediastinal B-cell lymphomas.

Drexler HG, Ehrentraut S, Nagel S, Eberth S, MacLeod RA.

Leuk Res. 2015 Jan;39(1):18-29. doi: 10.1016/j.leukres.2014.11.002. Epub 2014 Nov 21. Review.

PMID:
25480038
4.

Deregulated FOX genes in Hodgkin lymphoma.

Nagel S, Meyer C, Kaufmann M, Drexler HG, MacLeod RA.

Genes Chromosomes Cancer. 2014 Nov;53(11):917-33. doi: 10.1002/gcc.22204. Epub 2014 Jul 17.

PMID:
25043849
5.

Cell line cross-contamination: WSU-CLL is a known derivative of REH and is unsuitable as a model for chronic lymphocytic leukaemia.

International Cell Line Authentication Committee (ICLAC).

Leuk Res. 2014 Aug;38(8):999-1001. doi: 10.1016/j.leukres.2014.05.003. Epub 2014 May 23. No abstract available.

PMID:
24923861
6.

Repressed BMP signaling reactivates NKL homeobox gene MSX1 in a T-ALL subset.

Nagel S, Ehrentraut S, Meyer C, Kaufmann M, Drexler HG, MacLeod RA.

Leuk Lymphoma. 2015 Feb;56(2):480-91. doi: 10.3109/10428194.2014.924119. Epub 2014 Jun 12.

PMID:
24844359
7.

A recurrent 11q aberration pattern characterizes a subset of MYC-negative high-grade B-cell lymphomas resembling Burkitt lymphoma.

Salaverria I, Martin-Guerrero I, Wagener R, Kreuz M, Kohler CW, Richter J, Pienkowska-Grela B, Adam P, Burkhardt B, Claviez A, Damm-Welk C, Drexler HG, Hummel M, Jaffe ES, Küppers R, Lefebvre C, Lisfeld J, Löffler M, Macleod RA, Nagel I, Oschlies I, Rosolowski M, Russell RB, Rymkiewicz G, Schindler D, Schlesner M, Scholtysik R, Schwaenen C, Spang R, Szczepanowski M, Trümper L, Vater I, Wessendorf S, Klapper W, Siebert R; Molecular Mechanisms in Malignant Lymphoma Network Project; Berlin-Frankfurt-Münster Non-Hodgkin Lymphoma Group.

Blood. 2014 Feb 20;123(8):1187-98. doi: 10.1182/blood-2013-06-507996. Epub 2014 Jan 7.

8.

Inhibition of PI3K/mTOR overcomes nilotinib resistance in BCR-ABL1 positive leukemia cells through translational down-regulation of MDM2.

Ding J, Romani J, Zaborski M, MacLeod RA, Nagel S, Drexler HG, Quentmeier H.

PLoS One. 2013 Dec 11;8(12):e83510. doi: 10.1371/journal.pone.0083510. eCollection 2013.

9.

Oncogenic deregulation of NKL homeobox gene MSX1 in mantle cell lymphoma.

Nagel S, Ehrentraut S, Meyer C, Kaufmann M, Drexler HG, MacLeod RA.

Leuk Lymphoma. 2014 Aug;55(8):1893-903. doi: 10.3109/10428194.2013.864762. Epub 2014 Feb 17.

PMID:
24237447
10.

Massive transcriptional perturbation in subgroups of diffuse large B-cell lymphomas.

Rosolowski M, Läuter J, Abramov D, Drexler HG, Hummel M, Klapper W, Macleod RA, Pellissery S, Horn F, Siebert R, Loeffler M.

PLoS One. 2013 Nov 4;8(11):e76287. doi: 10.1371/journal.pone.0076287. eCollection 2013.

11.

Beware imposters: MA-1, a novel MALT lymphoma cell line, is misidentified and corresponds to Pfeiffer, a diffuse large B-cell lymphoma cell line.

Capes-Davis A, Alston-Roberts C, Kerrigan L, Reid YA, Barrett T, Burnett EC, Cooper JR, Freshney RI, Healy L, Kohara A, Korch C, Masters JR, Nakamura Y, Nims RW, Storts DR, Dirks WG, MacLeod RA, Drexler HG.

Genes Chromosomes Cancer. 2013 Oct;52(10):986-8. doi: 10.1002/gcc.22094. Epub 2013 Aug 1. No abstract available.

PMID:
23907998
12.

Ectopic expression of homeobox gene NKX2-1 in diffuse large B-cell lymphoma is mediated by aberrant chromatin modifications.

Nagel S, Ehrentraut S, Tomasch J, Quentmeier H, Meyer C, Kaufmann M, Drexler HG, MacLeod RA.

PLoS One. 2013 Apr 29;8(4):e61447. doi: 10.1371/journal.pone.0061447. Print 2013. Erratum in: PLoS One. 2013;8(6). doi:10.1371/annotation/3989404d-132f-4f07-a39e-c060d9094611.

13.

Chromothripsis in Hodgkin lymphoma.

Nagel S, Meyer C, Quentmeier H, Kaufmann M, Drexler HG, MacLeod RA.

Genes Chromosomes Cancer. 2013 Aug;52(8):741-7. doi: 10.1002/gcc.22069. Epub 2013 Apr 30.

PMID:
23630094
14.

t(8;9)(p22;p24)/PCM1-JAK2 activates SOCS2 and SOCS3 via STAT5.

Ehrentraut S, Nagel S, Scherr ME, Schneider B, Quentmeier H, Geffers R, Kaufmann M, Meyer C, Prochorec-Sobieszek M, Ketterling RP, Knudson RA, Feldman AL, Kadin ME, Drexler HG, MacLeod RA.

PLoS One. 2013;8(1):e53767. doi: 10.1371/journal.pone.0053767. Epub 2013 Jan 23.

15.

BCR-ABL1 expression in multiple myeloma cells: a case of mistaken identity?

MacLeod RA, Nagel S, Dirks W, Drexler HG.

Proc Natl Acad Sci U S A. 2013 Jan 22;110(4):E270-1. doi: 10.1073/pnas.1219862110. Epub 2013 Jan 14. No abstract available.

16.

Base-pair resolution DNA methylome of the EBV-positive Endemic Burkitt lymphoma cell line DAUDI determined by SOLiD bisulfite-sequencing.

Kreck B, Richter J, Ammerpohl O, Barann M, Esser D, Petersen BS, Vater I, Murga Penas EM, Bormann Chung CA, Seisenberger S, Lee Boyd V, Smallwood S, Drexler HG, Macleod RA, Hummel M, Krueger F, Häsler R, Schreiber S, Rosenstiel P, Franke A, Siebert R.

Leukemia. 2013 Aug;27(8):1751-3. doi: 10.1038/leu.2013.4. Epub 2013 Jan 11. No abstract available.

17.

U-2932: two clones in one cell line, a tool for the study of clonal evolution.

Quentmeier H, Amini RM, Berglund M, Dirks WG, Ehrentraut S, Geffers R, Macleod RA, Nagel S, Romani J, Scherr M, Zaborski M, Drexler HG.

Leukemia. 2013 Apr;27(5):1155-64. doi: 10.1038/leu.2012.358. Epub 2012 Dec 7.

PMID:
23295736
18.

Classical and molecular cytogenetic analysis.

MacLeod RA, Drexler HG.

Methods Mol Biol. 2013;946:39-60. doi: 10.1007/978-1-62703-128-8_4.

PMID:
23179825
19.

Recurrent mutation of the ID3 gene in Burkitt lymphoma identified by integrated genome, exome and transcriptome sequencing.

Richter J, Schlesner M, Hoffmann S, Kreuz M, Leich E, Burkhardt B, Rosolowski M, Ammerpohl O, Wagener R, Bernhart SH, Lenze D, Szczepanowski M, Paulsen M, Lipinski S, Russell RB, Adam-Klages S, Apic G, Claviez A, Hasenclever D, Hovestadt V, Hornig N, Korbel JO, Kube D, Langenberger D, Lawerenz C, Lisfeld J, Meyer K, Picelli S, Pischimarov J, Radlwimmer B, Rausch T, Rohde M, Schilhabel M, Scholtysik R, Spang R, Trautmann H, Zenz T, Borkhardt A, Drexler HG, Möller P, MacLeod RA, Pott C, Schreiber S, Trümper L, Loeffler M, Stadler PF, Lichter P, Eils R, Küppers R, Hummel M, Klapper W, Rosenstiel P, Rosenwald A, Brors B, Siebert R; ICGC MMML-Seq Project.

Nat Genet. 2012 Dec;44(12):1316-20. doi: 10.1038/ng.2469. Epub 2012 Nov 11.

PMID:
23143595
20.

Match criteria for human cell line authentication: where do we draw the line?

Capes-Davis A, Reid YA, Kline MC, Storts DR, Strauss E, Dirks WG, Drexler HG, MacLeod RA, Sykes G, Kohara A, Nakamura Y, Elmore E, Nims RW, Alston-Roberts C, Barallon R, Los GV, Nardone RM, Price PJ, Steuer A, Thomson J, Masters JR, Kerrigan L.

Int J Cancer. 2013 Jun 1;132(11):2510-9. doi: 10.1002/ijc.27931. Epub 2012 Nov 28.

PMID:
23136038
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