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Items: 1 to 20 of 89

1.

High-throughput transcriptomics reveals common and strain-specific responses of human macrophages to infection with Mycobacterium abscessus Smooth and Rough variants.

Aulicino A, Dinan AM, Miranda-CasoLuengo AA, Browne JA, Rue-Albrecht K, MacHugh DE, Loftus BJ.

BMC Genomics. 2015 Dec 9;16(1):1046. doi: 10.1186/s12864-015-2246-1.

2.

The MarR family transcription factor Rv1404 coordinates adaptation of Mycobacterium tuberculosis to acid stress via controlled expression of Rv1405c, a virulence-associated methyltransferase.

Healy C, Golby P, MacHugh DE, Gordon SV.

Tuberculosis (Edinb). 2015 Nov 10. pii: S1472-9792(15)30086-X. doi: 10.1016/j.tube.2015.10.003. [Epub ahead of print]

PMID:
26615221
3.

Iodine supplementation of the pregnant dam alters intestinal gene expression and immunoglobulin uptake in the newborn lamb.

McGovern FM, Magee DA, Browne JA, MacHugh DE, Boland TM.

Animal. 2015 Nov 20:1-9. [Epub ahead of print]

PMID:
26585074
4.

Genome sequencing of the extinct Eurasian wild aurochs, Bos primigenius, illuminates the phylogeography and evolution of cattle.

Park SD, Magee DA, McGettigan PA, Teasdale MD, Edwards CJ, Lohan AJ, Murphy A, Braud M, Donoghue MT, Liu Y, Chamberlain AT, Rue-Albrecht K, Schroeder S, Spillane C, Tai S, Bradley DG, Sonstegard TS, Loftus BJ, MacHugh DE.

Genome Biol. 2015 Oct 26;16:234. doi: 10.1186/s13059-015-0790-2.

5.

RNA sequencing provides exquisite insight into the manipulation of the alveolar macrophage by tubercle bacilli.

Nalpas NC, Magee DA, Conlon KM, Browne JA, Healy C, McLoughlin KE, Rue-Albrecht K, McGettigan PA, Killick KE, Gormley E, Gordon SV, MacHugh DE.

Sci Rep. 2015 Sep 8;5:13629. doi: 10.1038/srep13629.

6.

Differential gene expression in the endometrium reveals cytoskeletal and immunological genes in lactating dairy cows genetically divergent for fertility traits.

Moran B, Butler ST, Moore SG, MacHugh DE, Creevey CJ.

Reprod Fertil Dev. 2015 Aug 25. doi: 10.1071/RD15128. [Epub ahead of print]

PMID:
26304020
7.

The Identification of Circulating MiRNA in Bovine Serum and Their Potential as Novel Biomarkers of Early Mycobacterium avium subsp paratuberculosis Infection.

Farrell D, Shaughnessy RG, Britton L, MacHugh DE, Markey B, Gordon SV.

PLoS One. 2015 Jul 28;10(7):e0134310. doi: 10.1371/journal.pone.0134310. eCollection 2015.

8.

Genomic imprinting effects on complex traits in domesticated animal species.

O'Doherty AM, MacHugh DE, Spillane C, Magee DA.

Front Genet. 2015 Apr 24;6:156. doi: 10.3389/fgene.2015.00156. eCollection 2015. Review.

9.

Analysis of the Bovine Monocyte-Derived Macrophage Response to Mycobacterium avium Subspecies Paratuberculosis Infection Using RNA-seq.

Casey ME, Meade KG, Nalpas NC, Taraktsoglou M, Browne JA, Killick KE, Park SD, Gormley E, Hokamp K, Magee DA, MacHugh DE.

Front Immunol. 2015 Feb 4;6:23. doi: 10.3389/fimmu.2015.00023. eCollection 2015.

10.

MicroRNA profiling of the bovine alveolar macrophage response to Mycobacterium bovis infection suggests pathogen survival is enhanced by microRNA regulation of endocytosis and lysosome trafficking.

Vegh P, Magee DA, Nalpas NC, Bryan K, McCabe MS, Browne JA, Conlon KM, Gordon SV, Bradley DG, MacHugh DE, Lynn DJ.

Tuberculosis (Edinb). 2015 Jan;95(1):60-7.

PMID:
25692199
11.

Prehistoric genomes reveal the genetic foundation and cost of horse domestication.

Schubert M, Jónsson H, Chang D, Der Sarkissian C, Ermini L, Ginolhac A, Albrechtsen A, Dupanloup I, Foucal A, Petersen B, Fumagalli M, Raghavan M, Seguin-Orlando A, Korneliussen TS, Velazquez AM, Stenderup J, Hoover CA, Rubin CJ, Alfarhan AH, Alquraishi SA, Al-Rasheid KA, MacHugh DE, Kalbfleisch T, MacLeod JN, Rubin EM, Sicheritz-Ponten T, Andersson L, Hofreiter M, Marques-Bonet T, Gilbert MT, Nielsen R, Excoffier L, Willerslev E, Shapiro B, Orlando L.

Proc Natl Acad Sci U S A. 2014 Dec 30;111(52):E5661-9. doi: 10.1073/pnas.1416991111. Epub 2014 Dec 15.

12.

Comparative functional genomics and the bovine macrophage response to strains of the mycobacterium genus.

Rue-Albrecht K, Magee DA, Killick KE, Nalpas NC, Gordon SV, MacHugh DE.

Front Immunol. 2014 Nov 5;5:536. doi: 10.3389/fimmu.2014.00536. eCollection 2014. Review.

13.

Definition of the cattle killer cell Ig-like receptor gene family: comparison with aurochs and human counterparts.

Sanderson ND, Norman PJ, Guethlein LA, Ellis SA, Williams C, Breen M, Park SD, Magee DA, Babrzadeh F, Warry A, Watson M, Bradley DG, MacHugh DE, Parham P, Hammond JA.

J Immunol. 2014 Dec 15;193(12):6016-30. doi: 10.4049/jimmunol.1401980. Epub 2014 Nov 14.

14.

Key Hub and Bottleneck Genes Differentiate the Macrophage Response to Virulent and Attenuated Mycobacterium bovis.

Killick KE, Magee DA, Park SD, Taraktsoglou M, Browne JA, Conlon KM, Nalpas NC, Gormley E, Gordon SV, MacHugh DE, Hokamp K.

Front Immunol. 2014 Oct 1;5:422. doi: 10.3389/fimmu.2014.00422. eCollection 2014.

15.

RNA-seq Transcriptional Profiling of Peripheral Blood Leukocytes from Cattle Infected with Mycobacterium bovis.

McLoughlin KE, Nalpas NC, Rue-Albrecht K, Browne JA, Magee DA, Killick KE, Park SD, Hokamp K, Meade KG, O'Farrelly C, Gormley E, Gordon SV, MacHugh DE.

Front Immunol. 2014 Aug 26;5:396. doi: 10.3389/fimmu.2014.00396. eCollection 2014.

16.

Imprinted loci in domestic livestock species as epigenomic targets for artificial selection of complex traits.

Magee DA, Spillane C, Berkowicz EW, Sikora KM, MacHugh DE.

Anim Genet. 2014 Aug;45 Suppl 1:25-39. doi: 10.1111/age.12168. Epub 2014 Jul 2. Review.

PMID:
24990393
17.

Innate cytokine profiling of bovine alveolar macrophages reveals commonalities and divergence in the response to Mycobacterium bovis and Mycobacterium tuberculosis infection.

Magee DA, Conlon KM, Nalpas NC, Browne JA, Pirson C, Healy C, McLoughlin KE, Chen J, Vordermeier HM, Gormley E, MacHugh DE, Gordon SV.

Tuberculosis (Edinb). 2014 Jul;94(4):441-50. doi: 10.1016/j.tube.2014.04.004. Epub 2014 May 5.

PMID:
24882682
18.

Profiling microRNA expression in bovine alveolar macrophages using RNA-seq.

Vegh P, Foroushani AB, Magee DA, McCabe MS, Browne JA, Nalpas NC, Conlon KM, Gordon SV, Bradley DG, MacHugh DE, Lynn DJ.

Vet Immunol Immunopathol. 2013 Oct 1;155(4):238-44. doi: 10.1016/j.vetimm.2013.08.004. Epub 2013 Aug 24.

PMID:
24021155
19.

Receptor-mediated recognition of mycobacterial pathogens.

Killick KE, Ní Cheallaigh C, O'Farrelly C, Hokamp K, MacHugh DE, Harris J.

Cell Microbiol. 2013 Sep;15(9):1484-95. doi: 10.1111/cmi.12161. Epub 2013 Jul 29. Review.

PMID:
23795683
20.

Whole-transcriptome, high-throughput RNA sequence analysis of the bovine macrophage response to Mycobacterium bovis infection in vitro.

Nalpas NC, Park SD, Magee DA, Taraktsoglou M, Browne JA, Conlon KM, Rue-Albrecht K, Killick KE, Hokamp K, Lohan AJ, Loftus BJ, Gormley E, Gordon SV, MacHugh DE.

BMC Genomics. 2013 Apr 8;14:230. doi: 10.1186/1471-2164-14-230.

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