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Results: 1 to 20 of 244

1.

Huntingtin promotes mTORC1 signaling in the pathogenesis of Huntington's disease.

Pryor WM, Biagioli M, Shahani N, Swarnkar S, Huang WC, Page DT, MacDonald ME, Subramaniam S.

Sci Signal. 2014 Oct 28;7(349):ra103. doi: 10.1126/scisignal.2005633.

PMID:
25351248
[PubMed - in process]
2.

Huntingtin Supplies a csaA-Independent Function Essential for EDTA-Resistant Homotypic Cell Adhesion in Dictyostelium discoideum.

Thompson MN, MacDonald ME, Gusella JF, Myre MA.

J Huntingtons Dis. 2014;3(3):261-71. doi: 10.3233/JHD-140112.

PMID:
25300330
[PubMed - in process]
3.

Understanding healthy pregnancies: the perspective of Inuit midwives in northwestern Quebec.

Macdonald ME, Bathory LW, Shenker H, Weiler H, Berry M, Sharma A, Rodd C.

Can J Rural Med. 2014 Fall;19(4):128-33.

PMID:
25291037
[PubMed - in process]
Free Article
4.

Excluding parental grief: A critical discourse analysis of bereavement accommodation in Canadian labour standards.

Macdonald ME, Kennedy K, Moll S, Pineda C, Mitchell LM, Stephenson PH, Cadell S.

Work. 2014 Sep 23. [Epub ahead of print]

PMID:
25248540
[PubMed - as supplied by publisher]
5.

The Drosophila Huntington's disease gene ortholog dhtt influences chromatin regulation during development.

Dietz KN, Di Stefano L, Maher RC, Zhu H, Macdonald ME, Gusella JF, Walker JA.

Hum Mol Genet. 2014 Aug 28. pii: ddu446. [Epub ahead of print]

PMID:
25168387
[PubMed - as supplied by publisher]
6.

Genetic modifiers of Huntington's disease.

Gusella JF, MacDonald ME, Lee JM.

Mov Disord. 2014 Sep 15;29(11):1359-65. doi: 10.1002/mds.26001. Epub 2014 Aug 25.

PMID:
25154728
[PubMed - in process]
7.

Beyond consent in research. Revisiting vulnerability in deep brain stimulation for psychiatric disorders.

Bell E, Racine E, Chiasson P, Dufourcq-Brana M, Dunn LB, Fins JJ, Ford PJ, Glannon W, Lipsman N, Macdonald ME, Mathews DJ, McAndrews MP.

Camb Q Healthc Ethics. 2014 Jul;23(3):361-8. doi: 10.1017/S0963180113000984. Epub 2014 May 27.

PMID:
24865371
[PubMed - in process]
8.

Affirming professional identities through an apprenticeship: insights from a four-year longitudinal case study.

Boudreau JD, Macdonald ME, Steinert Y.

Acad Med. 2014 Jul;89(7):1038-45. doi: 10.1097/ACM.0000000000000293.

PMID:
24826856
[PubMed - indexed for MEDLINE]
9.

HD CAGnome: a search tool for huntingtin CAG repeat length-correlated genes.

Galkina EI, Shin A, Coser KR, Shioda T, Kohane IS, Seong IS, Wheeler VC, Gusella JF, Macdonald ME, Lee JM.

PLoS One. 2014 Apr 21;9(4):e95556. doi: 10.1371/journal.pone.0095556. eCollection 2014.

PMID:
24751919
[PubMed - in process]
Free PMC Article
10.

MicroRNAs located in the Hox gene clusters are implicated in huntington's disease pathogenesis.

Hoss AG, Kartha VK, Dong X, Latourelle JC, Dumitriu A, Hadzi TC, Macdonald ME, Gusella JF, Akbarian S, Chen JF, Weng Z, Myers RH.

PLoS Genet. 2014 Feb 27;10(2):e1004188. doi: 10.1371/journal.pgen.1004188. eCollection 2014 Feb.

PMID:
24586208
[PubMed - in process]
Free PMC Article
11.

A relational ethical approach to end-of-life delirium.

Wright DK, Brajtman S, Macdonald ME.

J Pain Symptom Manage. 2014 Aug;48(2):191-8. doi: 10.1016/j.jpainsymman.2013.08.015. Epub 2014 Jan 10.

PMID:
24417807
[PubMed - in process]
12.

A broad phenotypic screen identifies novel phenotypes driven by a single mutant allele in Huntington's disease CAG knock-in mice.

Hölter SM, Stromberg M, Kovalenko M, Garrett L, Glasl L, Lopez E, Guide J, Götz A, Hans W, Becker L, Rathkolb B, Rozman J, Schrewed A, Klingenspor M, Klopstock T, Schulz H, Wolf E, Wursta W, Gillis T, Wakimoto H, Seidman J, MacDonald ME, Cotman S, Gailus-Durner V, Fuchs H, de Angelis MH, Lee JM, Wheeler VC.

PLoS One. 2013 Nov 22;8(11):e80923. doi: 10.1371/journal.pone.0080923. eCollection 2013.

PMID:
24278347
[PubMed - in process]
Free PMC Article
13.

Candidate glutamatergic and dopaminergic pathway gene variants do not influence Huntington's disease motor onset.

Ramos EM, Latourelle JC, Gillis T, Mysore JS, Squitieri F, Di Pardo A, Di Donato S, Gellera C, Hayden MR, Morrison PJ, Nance M, Ross CA, Margolis RL, Gomez-Tortosa E, Ayuso C, Suchowersky O, Trent RJ, McCusker E, Novelletto A, Frontali M, Jones R, Ashizawa T, Frank S, Saint-Hilaire MH, Hersch SM, Rosas HD, Lucente D, Harrison MB, Zanko A, Abramson RK, Marder K, Gusella JF, Lee JM, Alonso I, Sequeiros J, Myers RH, Macdonald ME.

Neurogenetics. 2013 Nov;14(3-4):173-9. doi: 10.1007/s10048-013-0364-y. Epub 2013 May 4.

PMID:
23644918
[PubMed - indexed for MEDLINE]
Free PMC Article
14.

Integrated systems approach identifies genetic nodes and networks in late-onset Alzheimer's disease.

Zhang B, Gaiteri C, Bodea LG, Wang Z, McElwee J, Podtelezhnikov AA, Zhang C, Xie T, Tran L, Dobrin R, Fluder E, Clurman B, Melquist S, Narayanan M, Suver C, Shah H, Mahajan M, Gillis T, Mysore J, MacDonald ME, Lamb JR, Bennett DA, Molony C, Stone DJ, Gudnason V, Myers AJ, Schadt EE, Neumann H, Zhu J, Emilsson V.

Cell. 2013 Apr 25;153(3):707-20. doi: 10.1016/j.cell.2013.03.030.

PMID:
23622250
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Health consumption as work: the home pregnancy test as a domesticated health tool.

Childerhose JE, Macdonald ME.

Soc Sci Med. 2013 Jun;86:1-8. doi: 10.1016/j.socscimed.2013.02.035. Epub 2013 Mar 1.

PMID:
23608088
[PubMed - indexed for MEDLINE]
16.

Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy.

Lee JM, Galkina EI, Levantovsky RM, Fossale E, Anne Anderson M, Gillis T, Srinidhi Mysore J, Coser KR, Shioda T, Zhang B, Furia MD, Derry J, Kohane IS, Seong IS, Wheeler VC, Gusella JF, MacDonald ME.

Hum Mol Genet. 2013 Aug 15;22(16):3227-38. doi: 10.1093/hmg/ddt176. Epub 2013 Apr 16.

PMID:
23595883
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

The effect of pomegranate extract on coronary artery atherosclerosis in SR-BI/APOE double knockout mice.

Al-Jarallah A, Igdoura F, Zhang Y, Tenedero CB, White EJ, MacDonald ME, Igdoura SA, Trigatti BL.

Atherosclerosis. 2013 May;228(1):80-9. doi: 10.1016/j.atherosclerosis.2013.02.025. Epub 2013 Mar 7.

PMID:
23528829
[PubMed - indexed for MEDLINE]
18.

Further molecular characterisation of the OVT73 transgenic sheep model of Huntington's disease identifies cortical aggregates.

Huntington's Disease Sheep Collaborative Research Group, Reid SJ, Patassini S, Handley RR, Rudiger SR, McLaughlan CJ, Osmand A, Jacobsen JC, Morton AJ, Weiss A, Waldvogel HJ, MacDonald ME, Gusella JF, Bawden CS, Faull RL, Snell RG.

J Huntingtons Dis. 2013;2(3):279-95. doi: 10.3233/JHD-130067.

PMID:
25062676
[PubMed - indexed for MEDLINE]
19.

Disruption of a large intergenic noncoding RNA in subjects with neurodevelopmental disabilities.

Talkowski ME, Maussion G, Crapper L, Rosenfeld JA, Blumenthal I, Hanscom C, Chiang C, Lindgren A, Pereira S, Ruderfer D, Diallo AB, Lopez JP, Turecki G, Chen ES, Gigek C, Harris DJ, Lip V, An Y, Biagioli M, Macdonald ME, Lin M, Haggarty SJ, Sklar P, Purcell S, Kellis M, Schwartz S, Shaffer LG, Natowicz MR, Shen Y, Morton CC, Gusella JF, Ernst C.

Am J Hum Genet. 2012 Dec 7;91(6):1128-34. doi: 10.1016/j.ajhg.2012.10.016.

PMID:
23217328
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

The limitations of language: male participants, stoicism, and the qualitative research interview.

Affleck W, Glass K, Macdonald ME.

Am J Mens Health. 2013 Mar;7(2):155-62. doi: 10.1177/1557988312464038. Epub 2012 Oct 22.

PMID:
23093076
[PubMed - indexed for MEDLINE]

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