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Maize Domestication and Anti-Herbivore Defences: Leaf-Specific Dynamics during Early Ontogeny of Maize and Its Wild Ancestors.

Maag D, Erb M, Bernal JS, Wolfender JL, Turlings TC, Glauser G.

PLoS One. 2015 Aug 12;10(8):e0135722. doi: 10.1371/journal.pone.0135722. eCollection 2015.


Mechanistic Dissection of PARP1 Trapping and the Impact on In Vivo Tolerability and Efficacy of PARP Inhibitors.

Hopkins TA, Shi Y, Rodriguez LE, Solomon LR, Donawho CK, DiGiammarino EL, Panchal SC, Wilsbacher JL, Gao W, Olson AM, Stolarik DF, Osterling DJ, Johnson EF, Maag D.

Mol Cancer Res. 2015 Nov;13(11):1465-77. doi: 10.1158/1541-7786.MCR-15-0191-T. Epub 2015 Jul 27.


Discovery of A-893, A New Cell-Active Benzoxazinone Inhibitor of Lysine Methyltransferase SMYD2.

Sweis RF, Wang Z, Algire M, Arrowsmith CH, Brown PJ, Chiang GG, Guo J, Jakob CG, Kennedy S, Li F, Maag D, Shaw B, Soni NB, Vedadi M, Pappano WN.

ACS Med Chem Lett. 2015 Apr 29;6(6):695-700. doi: 10.1021/acsmedchemlett.5b00124. eCollection 2015 Jun 11.


Pyrimidine-based tricyclic molecules as potent and orally efficacious inhibitors of wee1 kinase.

Tong Y, Torrent M, Florjancic AS, Bromberg KD, Buchanan FG, Ferguson DC, Johnson EF, Lasko LM, Maag D, Merta PJ, Olson AM, Osterling DJ, Soni N, Shoemaker AR, Penning TD.

ACS Med Chem Lett. 2014 Aug 6;6(1):58-62. doi: 10.1021/ml5002745. eCollection 2015 Jan 8.


Defensive weapons and defense signals in plants: some metabolites serve both roles.

Maag D, Erb M, Köllner TG, Gershenzon J.

Bioessays. 2015 Feb;37(2):167-74. doi: 10.1002/bies.201400124. Epub 2014 Nov 12.


Within-plant distribution of 1,4-benzoxazin-3-ones contributes to herbivore niche differentiation in maize.

Köhler A, Maag D, Veyrat N, Glauser G, Wolfender JL, Turlings TC, Erb M.

Plant Cell Environ. 2015 Jun;38(6):1081-93. doi: 10.1111/pce.12464. Epub 2014 Nov 28.


Discovery and development of potent and selective inhibitors of histone methyltransferase g9a.

Sweis RF, Pliushchev M, Brown PJ, Guo J, Li F, Maag D, Petros AM, Soni NB, Tse C, Vedadi M, Michaelides MR, Chiang GG, Pappano WN.

ACS Med Chem Lett. 2014 Jan 2;5(2):205-9. doi: 10.1021/ml400496h. eCollection 2014 Feb 13.


3-β-D-Glucopyranosyl-6-methoxy-2-benzoxazolinone (MBOA-N-Glc) is an insect detoxification product of maize 1,4-benzoxazin-3-ones.

Maag D, Dalvit C, Thevenet D, Köhler A, Wouters FC, Vassão DG, Gershenzon J, Wolfender JL, Turlings TC, Erb M, Glauser G.

Phytochemistry. 2014 Jun;102:97-105. doi: 10.1016/j.phytochem.2014.03.018. Epub 2014 Apr 5.


Gall volatiles defend aphids against a browsing mammal.

Rostás M, Maag D, Ikegami M, Inbar M.

BMC Evol Biol. 2013 Sep 11;13:193. doi: 10.1186/1471-2148-13-193.


PGC-1α improves glucose homeostasis in skeletal muscle in an activity-dependent manner.

Summermatter S, Shui G, Maag D, Santos G, Wenk MR, Handschin C.

Diabetes. 2013 Jan;62(1):85-95. doi: 10.2337/db12-0291. Epub 2012 Oct 18.


Iniparib nonselectively modifies cysteine-containing proteins in tumor cells and is not a bona fide PARP inhibitor.

Liu X, Shi Y, Maag DX, Palma JP, Patterson MJ, Ellis PA, Surber BW, Ready DB, Soni NB, Ladror US, Xu AJ, Iyer R, Harlan JE, Solomon LR, Donawho CK, Penning TD, Johnson EF, Shoemaker AR.

Clin Cancer Res. 2012 Jan 15;18(2):510-23. doi: 10.1158/1078-0432.CCR-11-1973. Epub 2011 Nov 29.


Amino acid signaling to mTOR mediated by inositol polyphosphate multikinase.

Kim S, Kim SF, Maag D, Maxwell MJ, Resnick AC, Juluri KR, Chakraborty A, Koldobskiy MA, Cha SH, Barrow R, Snowman AM, Snyder SH.

Cell Metab. 2011 Feb 2;13(2):215-21. doi: 10.1016/j.cmet.2011.01.007.


Inositol polyphosphate multikinase is a physiologic PI3-kinase that activates Akt/PKB.

Maag D, Maxwell MJ, Hardesty DA, Boucher KL, Choudhari N, Hanno AG, Ma JF, Snowman AS, Pietropaoli JW, Xu R, Storm PB, Saiardi A, Snyder SH, Resnick AC.

Proc Natl Acad Sci U S A. 2011 Jan 25;108(4):1391-6. doi: 10.1073/pnas.1017831108. Epub 2011 Jan 10.


Inositol pyrophosphates inhibit Akt signaling, thereby regulating insulin sensitivity and weight gain.

Chakraborty A, Koldobskiy MA, Bello NT, Maxwell M, Potter JJ, Juluri KR, Maag D, Kim S, Huang AS, Dailey MJ, Saleh M, Snowman AM, Moran TH, Mezey E, Snyder SH.

Cell. 2010 Dec 10;143(6):897-910. doi: 10.1016/j.cell.2010.11.032.


Synthesis of monodisperse oligo(1,4-phenyleneethynylene-alt-1,4-triptycyleneethynylene)s.

Maag D, Kottke T, Schulte M, Godt A.

J Org Chem. 2009 Oct 16;74(20):7733-42. doi: 10.1021/jo9009744.


Glutamatergic regulation of serine racemase via reversal of PIP2 inhibition.

Mustafa AK, van Rossum DB, Patterson RL, Maag D, Ehmsen JT, Gazi SK, Chakraborty A, Barrow RK, Amzel LM, Snyder SH.

Proc Natl Acad Sci U S A. 2009 Feb 24;106(8):2921-6. doi: 10.1073/pnas.0813105106. Epub 2009 Feb 4.


Pirt, a phosphoinositide-binding protein, functions as a regulatory subunit of TRPV1.

Kim AY, Tang Z, Liu Q, Patel KN, Maag D, Geng Y, Dong X.

Cell. 2008 May 2;133(3):475-85. doi: 10.1016/j.cell.2008.02.053.


Dissociation of eIF1 from the 40S ribosomal subunit is a key step in start codon selection in vivo.

Cheung YN, Maag D, Mitchell SF, Fekete CA, Algire MA, Takacs JE, Shirokikh N, Pestova T, Lorsch JR, Hinnebusch AG.

Genes Dev. 2007 May 15;21(10):1217-30.


The eukaryotic translation initiation factors eIF1 and eIF1A induce an open conformation of the 40S ribosome.

Passmore LA, Schmeing TM, Maag D, Applefield DJ, Acker MG, Algire MA, Lorsch JR, Ramakrishnan V.

Mol Cell. 2007 Apr 13;26(1):41-50.


N- and C-terminal residues of eIF1A have opposing effects on the fidelity of start codon selection.

Fekete CA, Mitchell SF, Cherkasova VA, Applefield D, Algire MA, Maag D, Saini AK, Lorsch JR, Hinnebusch AG.

EMBO J. 2007 Mar 21;26(6):1602-14. Epub 2007 Mar 1.

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