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Results: 1 to 20 of 88

1.

Krüppel-like factor 6 regulates mitochondrial function in the kidney.

Mallipattu SK, Horne SJ, D'Agati V, Narla G, Liu R, Frohman MA, Dickman K, Chen EY, Ma'ayan A, Bialkowska AB, Ghaleb AM, Nandan MO, Jain MK, Daehn I, Chuang PY, Yang VW, He JC.

J Clin Invest. 2015 Mar 2;125(3):1347-61. doi: 10.1172/JCI77084. Epub 2015 Feb 17.

PMID:
25689250
2.

Histone H3.3 and its proteolytically processed form drive a cellular senescence programme.

Duarte LF, Young AR, Wang Z, Wu HA, Panda T, Kou Y, Kapoor A, Hasson D, Mills NR, Ma'ayan A, Narita M, Bernstein E.

Nat Commun. 2014 Nov 14;5:5210. doi: 10.1038/ncomms6210.

PMID:
25394905
3.

Synaptic, transcriptional and chromatin genes disrupted in autism.

De Rubeis S, He X, Goldberg AP, Poultney CS, Samocha K, Cicek AE, Kou Y, Liu L, Fromer M, Walker S, Singh T, Klei L, Kosmicki J, Shih-Chen F, Aleksic B, Biscaldi M, Bolton PF, Brownfeld JM, Cai J, Campbell NG, Carracedo A, Chahrour MH, Chiocchetti AG, Coon H, Crawford EL, Curran SR, Dawson G, Duketis E, Fernandez BA, Gallagher L, Geller E, Guter SJ, Hill RS, Ionita-Laza J, Jimenz Gonzalez P, Kilpinen H, Klauck SM, Kolevzon A, Lee I, Lei I, Lei J, Lehtimäki T, Lin CF, Ma'ayan A, Marshall CR, McInnes AL, Neale B, Owen MJ, Ozaki N, Parellada M, Parr JR, Purcell S, Puura K, Rajagopalan D, Rehnström K, Reichenberg A, Sabo A, Sachse M, Sanders SJ, Schafer C, Schulte-Rüther M, Skuse D, Stevens C, Szatmari P, Tammimies K, Valladares O, Voran A, Li-San W, Weiss LA, Willsey AJ, Yu TW, Yuen RK; DDD Study; Homozygosity Mapping Collaborative for Autism; UK10K Consortium, Cook EH, Freitag CM, Gill M, Hultman CM, Lehner T, Palotie A, Schellenberg GD, Sklar P, State MW, Sutcliffe JS, Walsh CA, Scherer SW, Zwick ME, Barett JC, Cutler DJ, Roeder K, Devlin B, Daly MJ, Buxbaum JD.

Nature. 2014 Nov 13;515(7526):209-15. doi: 10.1038/nature13772. Epub 2014 Oct 29.

PMID:
25363760
4.

A blueprint of cell identity.

Ma'ayan A, Duan Q.

Nat Biotechnol. 2014 Oct;32(10):1007-8. doi: 10.1038/nbt.3035. No abstract available.

5.

Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells.

Xu H, Ang YS, Sevilla A, Lemischka IR, Ma'ayan A.

PLoS Comput Biol. 2014 Aug 14;10(8):e1003777. doi: 10.1371/journal.pcbi.1003777. eCollection 2014 Aug.

6.

Lean Big Data integration in systems biology and systems pharmacology.

Ma'ayan A, Rouillard AD, Clark NR, Wang Z, Duan Q, Kou Y.

Trends Pharmacol Sci. 2014 Sep;35(9):450-60. doi: 10.1016/j.tips.2014.07.001. Epub 2014 Aug 7.

PMID:
25109570
7.

Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.

Duan Q, Wang Z, Fernandez NF, Rouillard AD, Tan CM, Benes CH, Ma'ayan A.

Bioinformatics. 2014 Nov 15;30(22):3289-90. doi: 10.1093/bioinformatics/btu526. Epub 2014 Aug 6.

PMID:
25100688
8.

Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte.

Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE.

PLoS One. 2014 Jun 20;9(6):e100660. doi: 10.1371/journal.pone.0100660. eCollection 2014.

9.

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.

Duan Q, Flynn C, Niepel M, Hafner M, Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub TR, Sorger PK, Subramanian A, Ma'ayan A.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W449-60. doi: 10.1093/nar/gku476. Epub 2014 Jun 6.

10.

The characteristic direction: a geometrical approach to identify differentially expressed genes.

Clark NR, Hu KS, Feldmann AS, Kou Y, Chen EY, Duan Q, Ma'ayan A.

BMC Bioinformatics. 2014 Mar 21;15:79. doi: 10.1186/1471-2105-15-79.

11.

DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics.

Liu L, Lei J, Sanders SJ, Willsey AJ, Kou Y, Cicek AE, Klei L, Lu C, He X, Li M, Muhle RA, Ma'ayan A, Noonan JP, Sestan N, McFadden KA, State MW, Buxbaum JD, Devlin B, Roeder K.

Mol Autism. 2014 Mar 6;5(1):22. doi: 10.1186/2040-2392-5-22.

12.

B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development.

Baker SJ, Ma'ayan A, Lieu YK, John P, Reddy MV, Chen EY, Duan Q, Snoeck HW, Reddy EP.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3122-7. doi: 10.1073/pnas.1315464111. Epub 2014 Feb 10.

13.

Interconnected network motifs control podocyte morphology and kidney function.

Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R.

Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621.

14.

t4 workshop report: Pathways of Toxicity.

Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach S, Brennan R, Crofton KM, Gordon B, Fornace AJ Jr, Gaido K, Gerhold D, Haw R, Henney A, Ma'ayan A, McBride M, Monti S, Ochs MF, Pandey A, Sharan R, Stierum R, Tugendreich S, Willett C, Wittwehr C, Xia J, Patton GW, Arvidson K, Bouhifd M, Hogberg HT, Luechtefeld T, Smirnova L, Zhao L, Adeleye Y, Kanehisa M, Carmichael P, Andersen ME, Hartung T.

ALTEX. 2014;31(1):53-61. doi: 10.14573/altex.1309261. Epub 2013 Oct 15.

15.

Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder.

Poultney CS, Goldberg AP, Drapeau E, Kou Y, Harony-Nicolas H, Kajiwara Y, De Rubeis S, Durand S, Stevens C, Rehnström K, Palotie A, Daly MJ, Ma'ayan A, Fromer M, Buxbaum JD.

Am J Hum Genet. 2013 Oct 3;93(4):607-19. doi: 10.1016/j.ajhg.2013.09.001.

16.

Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.

Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ.

Immunity. 2013 Sep 19;39(3):599-610. doi: 10.1016/j.immuni.2013.08.007. Epub 2013 Sep 5.

17.

Metasignatures identify two major subtypes of breast cancer.

Duan Q, Kou Y, Clark NR, Gordonov S, Ma'ayan A.

CPT Pharmacometrics Syst Pharmacol. 2013 Mar 27;2:e35. doi: 10.1038/psp.2013.11.

18.

ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.

Xu H, Baroukh C, Dannenfelser R, Chen EY, Tan CM, Kou Y, Kim YE, Lemischka IR, Ma'ayan A.

Database (Oxford). 2013 Jun 21;2013:bat045. doi: 10.1093/database/bat045. Print 2013.

19.

Induction of a hemogenic program in mouse fibroblasts.

Pereira CF, Chang B, Qiu J, Niu X, Papatsenko D, Hendry CE, Clark NR, Nomura-Kitabayashi A, Kovacic JC, Ma'ayan A, Schaniel C, Lemischka IR, Moore K.

Cell Stem Cell. 2013 Aug 1;13(2):205-18. doi: 10.1016/j.stem.2013.05.024. Epub 2013 Jun 13.

20.

Network2Canvas: network visualization on a canvas with enrichment analysis.

Tan CM, Chen EY, Dannenfelser R, Clark NR, Ma'ayan A.

Bioinformatics. 2013 Aug 1;29(15):1872-8. doi: 10.1093/bioinformatics/btt319. Epub 2013 Jun 7.

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