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Results: 1 to 20 of 84

1.

Construction and validation of a regulatory network for pluripotency and self-renewal of mouse embryonic stem cells.

Xu H, Ang YS, Sevilla A, Lemischka IR, Ma'ayan A.

PLoS Comput Biol. 2014 Aug 14;10(8):e1003777. doi: 10.1371/journal.pcbi.1003777. eCollection 2014 Aug.

PMID:
25122140
[PubMed - in process]
Free PMC Article
2.

Lean Big Data integration in systems biology and systems pharmacology.

Ma'ayan A, Rouillard AD, Clark NR, Wang Z, Duan Q, Kou Y.

Trends Pharmacol Sci. 2014 Sep;35(9):450-460. doi: 10.1016/j.tips.2014.07.001. Epub 2014 Aug 7. Review.

PMID:
25109570
[PubMed - as supplied by publisher]
3.

Drug/Cell-line Browser: interactive canvas visualization of cancer drug/cell-line viability assay datasets.

Duan Q, Wang Z, Fernandez NF, Rouillard AD, Tan CM, Benes CH, Ma'ayan A.

Bioinformatics. 2014 Aug 6. pii: btu526. [Epub ahead of print]

PMID:
25100688
[PubMed - as supplied by publisher]
4.

Proteomics analysis of the non-muscle myosin heavy chain IIa-enriched actin-myosin complex reveals multiple functions within the podocyte.

Hays T, Ma'ayan A, Clark NR, Tan CM, Teixeira A, Teixeira A, Choi JW, Burdis N, Jung SY, Bajaj AO, O'Malley BW, He JC, Hyink DP, Klotman PE.

PLoS One. 2014 Jun 20;9(6):e100660. doi: 10.1371/journal.pone.0100660. eCollection 2014.

PMID:
24949636
[PubMed - in process]
Free PMC Article
5.

LINCS Canvas Browser: interactive web app to query, browse and interrogate LINCS L1000 gene expression signatures.

Duan Q, Flynn C, Niepel M, Hafner M, Muhlich JL, Fernandez NF, Rouillard AD, Tan CM, Chen EY, Golub TR, Sorger PK, Subramanian A, Ma'ayan A.

Nucleic Acids Res. 2014 Jul;42(Web Server issue):W449-60. doi: 10.1093/nar/gku476. Epub 2014 Jun 6.

PMID:
24906883
[PubMed - in process]
Free Article
6.

The characteristic direction: a geometrical approach to identify differentially expressed genes.

Clark NR, Hu KS, Feldmann AS, Kou Y, Chen EY, Duan Q, Ma'ayan A.

BMC Bioinformatics. 2014 Mar 21;15:79. doi: 10.1186/1471-2105-15-79.

PMID:
24650281
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

DAWN: a framework to identify autism genes and subnetworks using gene expression and genetics.

Liu L, Lei J, Sanders SJ, Willsey AJ, Kou Y, Cicek AE, Klei L, Lu C, He X, Li M, Muhle RA, Ma'ayan A, Noonan JP, Sestan N, McFadden KA, State MW, Buxbaum JD, Devlin B, Roeder K.

Mol Autism. 2014 Mar 6;5(1):22. doi: 10.1186/2040-2392-5-22.

PMID:
24602502
[PubMed]
Free PMC Article
8.

B-myb is an essential regulator of hematopoietic stem cell and myeloid progenitor cell development.

Baker SJ, Ma'ayan A, Lieu YK, John P, Reddy MV, Chen EY, Duan Q, Snoeck HW, Reddy EP.

Proc Natl Acad Sci U S A. 2014 Feb 25;111(8):3122-7. doi: 10.1073/pnas.1315464111. Epub 2014 Feb 10.

PMID:
24516162
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

Interconnected network motifs control podocyte morphology and kidney function.

Azeloglu EU, Hardy SV, Eungdamrong NJ, Chen Y, Jayaraman G, Chuang PY, Fang W, Xiong H, Neves SR, Jain MR, Li H, Ma'ayan A, Gordon RE, He JC, Iyengar R.

Sci Signal. 2014 Feb 4;7(311):ra12. doi: 10.1126/scisignal.2004621.

PMID:
24497609
[PubMed - in process]
10.

t4 workshop report: Pathways of Toxicity.

Kleensang A, Maertens A, Rosenberg M, Fitzpatrick S, Lamb J, Auerbach S, Brennan R, Crofton KM, Gordon B, Fornace AJ Jr, Gaido K, Gerhold D, Haw R, Henney A, Ma'ayan A, McBride M, Monti S, Ochs MF, Pandey A, Sharan R, Stierum R, Tugendreich S, Willett C, Wittwehr C, Xia J, Patton GW, Arvidson K, Bouhifd M, Hogberg HT, Luechtefeld T, Smirnova L, Zhao L, Adeleye Y, Kanehisa M, Carmichael P, Andersen ME, Hartung T.

ALTEX. 2014;31(1):53-61. doi: 10.14573/altex.1309261. Epub 2013 Oct 15.

PMID:
24127042
[PubMed - in process]
Free PMC Article
11.

Identification of small exonic CNV from whole-exome sequence data and application to autism spectrum disorder.

Poultney CS, Goldberg AP, Drapeau E, Kou Y, Harony-Nicolas H, Kajiwara Y, De Rubeis S, Durand S, Stevens C, Rehnström K, Palotie A, Daly MJ, Ma'ayan A, Fromer M, Buxbaum JD.

Am J Hum Genet. 2013 Oct 3;93(4):607-19. doi: 10.1016/j.ajhg.2013.09.001.

PMID:
24094742
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Minimal differentiation of classical monocytes as they survey steady-state tissues and transport antigen to lymph nodes.

Jakubzick C, Gautier EL, Gibbings SL, Sojka DK, Schlitzer A, Johnson TE, Ivanov S, Duan Q, Bala S, Condon T, van Rooijen N, Grainger JR, Belkaid Y, Ma'ayan A, Riches DW, Yokoyama WM, Ginhoux F, Henson PM, Randolph GJ.

Immunity. 2013 Sep 19;39(3):599-610. doi: 10.1016/j.immuni.2013.08.007. Epub 2013 Sep 5.

PMID:
24012416
[PubMed - indexed for MEDLINE]
13.

Metasignatures identify two major subtypes of breast cancer.

Duan Q, Kou Y, Clark NR, Gordonov S, Ma'ayan A.

CPT Pharmacometrics Syst Pharmacol. 2013 Mar 27;2:e35. doi: 10.1038/psp.2013.11.

PMID:
23836026
[PubMed]
Free PMC Article
14.

ESCAPE: database for integrating high-content published data collected from human and mouse embryonic stem cells.

Xu H, Baroukh C, Dannenfelser R, Chen EY, Tan CM, Kou Y, Kim YE, Lemischka IR, Ma'ayan A.

Database (Oxford). 2013 Jun 21;2013:bat045. doi: 10.1093/database/bat045. Print 2013.

PMID:
23794736
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

Induction of a hemogenic program in mouse fibroblasts.

Pereira CF, Chang B, Qiu J, Niu X, Papatsenko D, Hendry CE, Clark NR, Nomura-Kitabayashi A, Kovacic JC, Ma'ayan A, Schaniel C, Lemischka IR, Moore K.

Cell Stem Cell. 2013 Aug 1;13(2):205-18. doi: 10.1016/j.stem.2013.05.024. Epub 2013 Jun 13.

PMID:
23770078
[PubMed - indexed for MEDLINE]
Free PMC Article
16.

Network2Canvas: network visualization on a canvas with enrichment analysis.

Tan CM, Chen EY, Dannenfelser R, Clark NR, Ma'ayan A.

Bioinformatics. 2013 Aug 1;29(15):1872-8. doi: 10.1093/bioinformatics/btt319. Epub 2013 Jun 7.

PMID:
23749960
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

ELK1 transcription factor linked to dysregulated striatal mu opioid receptor signaling network and OPRM1 polymorphism in human heroin abusers.

Sillivan SE, Whittard JD, Jacobs MM, Ren Y, Mazloom AR, Caputi FF, Horvath M, Keller E, Ma'ayan A, Pan YX, Chiang LW, Hurd YL.

Biol Psychiatry. 2013 Oct 1;74(7):511-9. doi: 10.1016/j.biopsych.2013.04.012. Epub 2013 May 20.

PMID:
23702428
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Enrichr: interactive and collaborative HTML5 gene list enrichment analysis tool.

Chen EY, Tan CM, Kou Y, Duan Q, Wang Z, Meirelles GV, Clark NR, Ma'ayan A.

BMC Bioinformatics. 2013 Apr 15;14:128. doi: 10.1186/1471-2105-14-128.

PMID:
23586463
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

Renoprotective effect of combined inhibition of angiotensin-converting enzyme and histone deacetylase.

Zhong Y, Chen EY, Liu R, Chuang PY, Mallipattu SK, Tan CM, Clark NR, Deng Y, Klotman PE, Ma'ayan A, He JC.

J Am Soc Nephrol. 2013 Apr;24(5):801-11. doi: 10.1681/ASN.2012060590. Epub 2013 Apr 4.

PMID:
23559582
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

Systems pharmacology meets predictive, preventive, personalized and participatory medicine.

Jenkins SL, Ma'ayan A.

Pharmacogenomics. 2013 Jan;14(2):119-22. doi: 10.2217/pgs.12.186. No abstract available.

PMID:
23327571
[PubMed - indexed for MEDLINE]
Free PMC Article

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