Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 6
1994 12
1995 27
1996 27
1997 27
1998 27
1999 27
2000 30
2001 26
2002 23
2003 38
2004 37
2005 45
2006 36
2007 46
2008 47
2009 57
2010 51
2011 59
2012 57
2013 47
2014 37
2015 40
2016 32
2017 24
2018 33
2019 36
2020 30
2021 27
2022 30
2023 15
2024 6

Text availability

Article attribute

Article type

Publication date

Search Results

971 results

Results by year

Filters applied: . Clear all
Page 1
MSX2 in ameloblast cell fate and activity.
Babajko S, de La Dure-Molla M, Jedeon K, Berdal A. Babajko S, et al. Front Physiol. 2015 Jan 5;5:510. doi: 10.3389/fphys.2014.00510. eCollection 2014. Front Physiol. 2015. PMID: 25601840 Free PMC article. Review.
Several transcription factors are candidates for enamel gene expression regulation and thus the control of enamel quality. Some of these factors, such as MSX2, are mainly confined to the dental epithelium. MSX2 homeoprotein controls several stages of the ameloblast …
Several transcription factors are candidates for enamel gene expression regulation and thus the control of enamel quality. Some of these fac …
MSX2 safeguards syncytiotrophoblast fate of human trophoblast stem cells.
Hornbachner R, Lackner A, Papuchova H, Haider S, Knöfler M, Mechtler K, Latos PA. Hornbachner R, et al. Proc Natl Acad Sci U S A. 2021 Sep 14;118(37):e2105130118. doi: 10.1073/pnas.2105130118. Proc Natl Acad Sci U S A. 2021. PMID: 34507999 Free PMC article.
Depletion of MSX2 resulted in activation of the syncytiotrophoblast transcriptional program, while forced expression of MSX2 blocked it. ...Increased H3K27ac and cBAF occupancy upon MSX2 depletion imply that MSX2 prevents premature syncytiotrophoblast …
Depletion of MSX2 resulted in activation of the syncytiotrophoblast transcriptional program, while forced expression of MSX2 b …
Enam expression is regulated by Msx2.
Ruspita I, Das P, Miyoshi K, Noma T, Snead ML, Bei M. Ruspita I, et al. Dev Dyn. 2023 Oct;252(10):1292-1302. doi: 10.1002/dvdy.598. Epub 2023 May 16. Dev Dyn. 2023. PMID: 37191055
Here, we have investigated the transcriptional regulation of the second most prominent enamel matrix protein, enamelin, and its regulation through the major odontogenic transcription factor, MSX2. RESULTS: Using in vitro and in vivo approaches, we identified that (a) Enam …
Here, we have investigated the transcriptional regulation of the second most prominent enamel matrix protein, enamelin, and its regulation t …
MSX2 inhibits the growth and migration of osteosarcoma cells by repressing SOX2.
Wu Y, Jin Y, Yamamoto N, Takeuchi A, Miwa S, Tsuchiya H, Yang Z. Wu Y, et al. Am J Transl Res. 2021 Jun 15;13(6):5851-5865. eCollection 2021. Am J Transl Res. 2021. PMID: 34306330 Free PMC article.
Osteosarcoma clinical samples and cells showed lower levels of MSX2 than normal healthy control samples. Overexpression of MSX2 led to a reduced activity of SOX2 and TNF-alpha, whereas MSX2 depletion did not contribute to upregulated SOX2 levels. ...Furthermo …
Osteosarcoma clinical samples and cells showed lower levels of MSX2 than normal healthy control samples. Overexpression of MSX2 …
Regulation of endogenous retrovirus-derived regulatory elements by GATA2/3 and MSX2 in human trophoblast stem cells.
Du C, Jiang J, Li Y, Yu M, Jin J, Chen S, Fan H, Macfarlan TS, Cao B, Sun MA. Du C, et al. Genome Res. 2023 Feb;33(2):197-207. doi: 10.1101/gr.277150.122. Epub 2023 Feb 17. Genome Res. 2023. PMID: 36806146 Free PMC article.
Here, by first focusing on MER41, a primate-specific ERV family previously linked to placenta and innate immunity, we uncover the binding motifs of multiple crucial trophoblast TFs (GATA2/3, MSX2, GRHL2) in addition to innate immunity TFs STAT1 and IRF1. Integration of ChI …
Here, by first focusing on MER41, a primate-specific ERV family previously linked to placenta and innate immunity, we uncover the binding mo …
CLU (clusterin) promotes mitophagic degradation of MSX2 through an AKT-DNM1L/Drp1 axis to maintain SOX2-mediated stemness in oral cancer stem cells.
Praharaj PP, Patra S, Mishra SR, Mukhopadhyay S, Klionsky DJ, Patil S, Bhutia SK. Praharaj PP, et al. Autophagy. 2023 Aug;19(8):2196-2216. doi: 10.1080/15548627.2023.2178876. Epub 2023 Mar 6. Autophagy. 2023. PMID: 36779631 Free PMC article.
More importantly, we also demonstrated that CLU-mediated mitophagy positively regulates oral CSCs through mitophagic degradation of MSX2 (msh homeobox 2), preventing its nuclear translocation from suppressing SOX2 activity and subsequent inhibition of cancer stemness and s …
More importantly, we also demonstrated that CLU-mediated mitophagy positively regulates oral CSCs through mitophagic degradation of MSX2 …
MSX2 represses tumor stem cell phenotypes within oral squamous cell carcinomas via SOX2 degradation.
Keyimu R, Tuerdi M, Zhao Z. Keyimu R, et al. Exp Biol Med (Maywood). 2021 Dec;246(24):2660-2670. doi: 10.1177/15353702211041029. Epub 2021 Aug 26. Exp Biol Med (Maywood). 2021. PMID: 34435915 Free PMC article. Retracted.
The results showed that MSX2 was remarkably downregulated in OSCC and that the MSX2 expression level was related to unfavorable outcomes in patients with OSCC. ...The OSCC2 cells exhibited decreased percentage of CD44(+)/CD24(-) cells, owing to MSX2 overexpre …
The results showed that MSX2 was remarkably downregulated in OSCC and that the MSX2 expression level was related to unfavorabl …
Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis.
Hughes MW, Jiang TX, Plikus MV, Guerrero-Juarez CF, Lin CH, Schafer C, Maxson R, Widelitz RB, Chuong CM. Hughes MW, et al. J Invest Dermatol. 2018 Sep;138(9):2041-2050. doi: 10.1016/j.jid.2018.02.043. Epub 2018 Mar 23. J Invest Dermatol. 2018. PMID: 29577917 Free PMC article.
WIHN is abrogated in germline and epithelial-specific Msx2 mutant mice. Unlike the full-length Msx2 promoter, a minimal Msx2 promoter fails activation in the wound center, suggesting complex regulation of Msx2 expression. The Msx2 promoter bindi …
WIHN is abrogated in germline and epithelial-specific Msx2 mutant mice. Unlike the full-length Msx2 promoter, a minimal Msx …
MiR-151b inhibits osteoblast differentiation via downregulating Msx2.
Liu F, Liang Y, Lin X. Liu F, et al. Connect Tissue Res. 2022 Mar;63(2):112-123. doi: 10.1080/03008207.2021.1882442. Epub 2021 Mar 10. Connect Tissue Res. 2022. PMID: 33691558
The interaction between miR-151b and Msx2 was confirmed by luciferase reporter assay and RNA pull-down. Moreover, overexpression of miR-151b significantly inhibited Msx2 in both MC3T3-E1 cells and primary osteoblasts, while miR-151b inhibitor had the opposite effect …
The interaction between miR-151b and Msx2 was confirmed by luciferase reporter assay and RNA pull-down. Moreover, overexpression of m …
An Msx2-Sp6-Follistatin Pathway Operates During Late Stages of Tooth Development to Control Amelogenesis.
Ruspita I, Das P, Xia Y, Kelangi S, Miyoshi K, Noma T, Snead ML, D'Souza RN, Bei M. Ruspita I, et al. Front Physiol. 2020 Oct 26;11:582610. doi: 10.3389/fphys.2020.582610. eCollection 2020. Front Physiol. 2020. PMID: 33192593 Free PMC article.
RESULTS: Using the above methods we identified that (i) Msx2 and Sp6 exhibit overlapping expression in secretory ameloblasts, (ii) Sp6 expression is reduced in the Msx2 mouse mutant secretoty ameloblasts, and (iii) that Msx2, like Sp6 inhibits follistatin exp …
RESULTS: Using the above methods we identified that (i) Msx2 and Sp6 exhibit overlapping expression in secretory ameloblasts, (ii) Sp …
971 results