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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1985 2
1987 1
1988 2
1991 1
1992 2
1993 4
1994 4
1996 4
1997 1
1998 2
1999 2
2000 2
2001 4
2002 2
2003 6
2004 5
2005 3
2006 6
2007 2
2008 3
2009 3
2010 6
2011 3
2012 6
2013 4
2014 3
2015 3
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2023 10
2024 5

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131 results

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Page 1
NOD-like receptor NLRC5 promotes neuroinflammation and inhibits neuronal survival in Parkinson's disease models.
Liu Z, Shen C, Li H, Tong J, Wu Y, Ma Y, Wang J, Wang Z, Li Q, Zhang X, Dong H, Yang Y, Yu M, Wang J, Zhou R, Fei J, Huang F. Liu Z, et al. J Neuroinflammation. 2023 Apr 18;20(1):96. doi: 10.1186/s12974-023-02755-4. J Neuroinflammation. 2023. PMID: 37072793 Free PMC article.
In the current study, we found that the expression of NLRC5 was increased in the nigrostriatal axis of mice with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride (MPTP)-induced PD, as well as i …
In the current study, we found that the expression of NLRC5 was increased in the nigrostriatal axis of mice with 1-methyl-4 …
Physiology of MPTP tremor.
Bergman H, Raz A, Feingold A, Nini A, Nelken I, Hansel D, Ben-Pazi H, Reches A. Bergman H, et al. Mov Disord. 1998;13 Suppl 3:29-34. doi: 10.1002/mds.870131305. Mov Disord. 1998. PMID: 9827591
Rhesus and vervet monkeys respond differently to treatment with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochloride neurotoxin (MPTP). ...The phase shift distribution of the oscillatory cross-corr …
Rhesus and vervet monkeys respond differently to treatment with 1-methyl-4-phenyl-1,2,3, …
Rhynchophylline alleviates neuroinflammation and regulates metabolic disorders in a mouse model of Parkinson's disease.
Zhang C, Xue Z, Zhu L, Zhou J, Zhuo L, Zhang J, Zhang X, Liu W, Han L, Liao W. Zhang C, et al. Food Funct. 2023 Apr 3;14(7):3208-3219. doi: 10.1039/d2fo02939a. Food Funct. 2023. PMID: 36919954
In this study, a mass spectrometry-based metabolomic strategy combined with neurobehavioral tests, serum biochemical assays, and immunohistochemistry were employed to decipher the protective mechanism of RIN against 1-methyl-4-phenyl-1,2, …
In this study, a mass spectrometry-based metabolomic strategy combined with neurobehavioral tests, serum biochemical assays, and immunohisto …
Myeloid-specific blockade of notch signaling alleviates dopaminergic neurodegeneration in Parkinson's disease by dominantly regulating resident microglia activation through NF-κB signaling.
Liang SQ, Li PH, Hu YY, Zhao JL, Shao FZ, Kuang F, Ren KX, Wei TX, Fan F, Feng L, Han H, Qin HY. Liang SQ, et al. Front Immunol. 2023 Aug 23;14:1193081. doi: 10.3389/fimmu.2023.1193081. eCollection 2023. Front Immunol. 2023. PMID: 37680624 Free PMC article.
Recombination signal-binding protein Jkappa (RBP-J)-mediated Notch signaling regulates macrophage development and activation. In this study, with an 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) hydroc …
Recombination signal-binding protein Jkappa (RBP-J)-mediated Notch signaling regulates macrophage development and activation. In this study, …
Acacetin, a flavone with diverse therapeutic potential in cancer, inflammation, infections and other metabolic disorders.
Singh S, Gupta P, Meena A, Luqman S. Singh S, et al. Food Chem Toxicol. 2020 Nov;145:111708. doi: 10.1016/j.fct.2020.111708. Epub 2020 Aug 29. Food Chem Toxicol. 2020. PMID: 32866514 Review.
Literature information revealed that acacetin exhibits an array of pharmacological potential including chemopreventive and cytotoxic properties in cancer cell lines, prevents ischemia/reperfusion/myocardial infarction-induced cardiac injury, lipopolysaccharide (LPS), 1-methyl-4-p …
Literature information revealed that acacetin exhibits an array of pharmacological potential including chemopreventive and cytotoxic propert …
Ferulic acid pretreatment mitigates MPTP-induced motor impairment and histopathological alterations in C57BL/6 mice.
Nagarajan S, Chellappan DR, Chinnaswamy P, Thulasingam S. Nagarajan S, et al. Pharm Biol. 2015;53(11):1591-601. doi: 10.3109/13880209.2014.993041. Epub 2015 Apr 10. Pharm Biol. 2015. PMID: 25857436
This study hypothesizes that supplementation of FA might combat oxidative stress-induced Parkinson's disease (PD). OBJECTIVE: To explore the effect of FA on 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydrochlorid …
This study hypothesizes that supplementation of FA might combat oxidative stress-induced Parkinson's disease (PD). OBJECTIVE: To explore the …
Experimental study of antiparkinsonian action of the harmine hydrochloride original compound.
Nurmaganbetov ZS, Arystan LI, Muldaeva GM, Haydargalieva LS, Adekenov SM. Nurmaganbetov ZS, et al. Pharmacol Rep. 2019 Dec;71(6):1050-1058. doi: 10.1016/j.pharep.2019.06.002. Epub 2019 Jun 6. Pharmacol Rep. 2019. PMID: 31605892
In this work, the antiparkinsonian action of a water-soluble form of harmine hydrochloride was studied. The present studies aim to research antiparkinsonian action of the harmine hydrochloride original compound. METHODS: To achieve the objective of the study, the au …
In this work, the antiparkinsonian action of a water-soluble form of harmine hydrochloride was studied. The present studies aim to re …
c-Abl-p38alpha signaling plays an important role in MPTP-induced neuronal death.
Wu R, Chen H, Ma J, He Q, Huang Q, Liu Q, Li M, Yuan Z. Wu R, et al. Cell Death Differ. 2016 Mar;23(3):542-52. doi: 10.1038/cdd.2015.135. Epub 2015 Oct 30. Cell Death Differ. 2016. PMID: 26517532 Free PMC article.
Here, we demonstrated that c-Abl plays an important role in oxidative stress-induced neuronal cell death. C-Abl, a nonreceptor tyrosine kinase, was activated in an 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine hydro …
Here, we demonstrated that c-Abl plays an important role in oxidative stress-induced neuronal cell death. C-Abl, a nonreceptor tyrosine kina …
Postconditioning Protection Against Myocardiocyte Anoxia/Reoxygenation Injury From Penehyclidine Hydrochloride.
Ren JY, Lin DM, Wang CB, Yang YL, Wang ZQ, Cui BQ, Ma J. Ren JY, et al. Drug Des Devel Ther. 2019 Nov 26;13:3977-3988. doi: 10.2147/DDDT.S224282. eCollection 2019. Drug Des Devel Ther. 2019. PMID: 32063699 Free PMC article.
BACKGROUND/AIMS: To investigate the postconditioning protective effect of penehyclidine hydrochloride (PHC) against anoxia/reoxygenation (A/R) injury in H9c2 cells along with the involved mechanism and timing effect. ...Cell apoptosis, oxidative stress, intracellular Ca(2+ …
BACKGROUND/AIMS: To investigate the postconditioning protective effect of penehyclidine hydrochloride (PHC) against anoxia/reoxygenat …
"Effect of valerenic acid on neuroinflammation in a MPTP-induced mouse model of Parkinson's disease".
Rodríguez-Cruz A, Romo-Mancillas A, Mendiola-Precoma J, Escobar-Cabrera JE, García-Alcocer G, Berumen LC. Rodríguez-Cruz A, et al. IBRO Rep. 2019 Dec 17;8:28-35. doi: 10.1016/j.ibror.2019.12.002. eCollection 2020 Jun. IBRO Rep. 2019. PMID: 31909290 Free PMC article.
Several biomolecules are interesting candidates for the regulation of inflammation and possible neuroprotection, such as valerenic acid, one of the main components of Valeriana officinalis. A 1-methyl-4-phenyl-1,2,3,6-tet …
Several biomolecules are interesting candidates for the regulation of inflammation and possible neuroprotection, such as valerenic acid, one …
131 results