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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1976 1
1977 1
1978 3
1979 2
1980 13
1981 14
1982 14
1983 27
1984 16
1985 17
1986 17
1987 13
1988 5
1989 8
1990 10
1991 13
1992 10
1993 6
1994 5
1995 7
1996 8
1997 7
1998 12
1999 12
2000 15
2001 22
2002 28
2003 29
2004 32
2005 30
2006 26
2007 24
2008 21
2009 28
2010 29
2011 18
2012 11
2013 12
2014 11
2015 10
2016 15
2017 11
2018 8
2019 7
2020 8
2021 4
2022 8
2023 8
2024 2

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617 results

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Page 1
Mevastatin promotes healing by targeting caveolin-1 to restore EGFR signaling.
Sawaya AP, Jozic I, Stone RC, Pastar I, Egger AN, Stojadinovic O, Glinos GD, Kirsner RS, Tomic-Canic M. Sawaya AP, et al. JCI Insight. 2019 Dec 5;4(23):e129320. doi: 10.1172/jci.insight.129320. JCI Insight. 2019. PMID: 31661463 Free PMC article.
To investigate the therapeutic potential of topical statins to restore healing in patients with DFUs, we performed next-generation sequencing on mevastatin-treated primary human keratinocytes. We found that mevastatin activated and modulated the EGF signaling to tri …
To investigate the therapeutic potential of topical statins to restore healing in patients with DFUs, we performed next-generation sequencin …
Mevastatin in colon cancer by spectroscopic and microscopic methods - Raman imaging and AFM studies.
Beton K, Wysocki P, Brozek-Pluska B. Beton K, et al. Spectrochim Acta A Mol Biomol Spectrosc. 2022 Apr 5;270:120726. doi: 10.1016/j.saa.2021.120726. Epub 2021 Dec 17. Spectrochim Acta A Mol Biomol Spectrosc. 2022. PMID: 34979441 Free article.
Based on vibrational features of colon cells: normal cells CCD-18Co, cancerous cells CaCo-2 and cancerous cells CaCo-2 treated by mevastatin in different concentrations and incubation times we have confirmed the influence of this statin on biochemistry composition of cance …
Based on vibrational features of colon cells: normal cells CCD-18Co, cancerous cells CaCo-2 and cancerous cells CaCo-2 treated by mevasta …
Mevastatin promotes neuronal survival against Abeta-induced neurotoxicity through AMPK activation.
Kornelius E, Li HH, Peng CH, Hsiao HW, Yang YS, Huang CN, Lin CL. Kornelius E, et al. Metab Brain Dis. 2017 Dec;32(6):1999-2007. doi: 10.1007/s11011-017-0091-4. Epub 2017 Aug 24. Metab Brain Dis. 2017. PMID: 28840430
However, the precise mechanisms involved in statin-inhibited Abeta toxicity remain unclear. In the present study, we report that mevastatin significantly protects against Abeta-induced neurotoxicity in SK-N-MC neuronal cells by restoring impaired insulin signaling. ...Thes …
However, the precise mechanisms involved in statin-inhibited Abeta toxicity remain unclear. In the present study, we report that mevastat …
Mevastatin inhibits ovarian theca-interstitial cell proliferation and steroidogenesis.
Izquierdo D, Foyouzi N, Kwintkiewicz J, Duleba AJ. Izquierdo D, et al. Fertil Steril. 2004 Oct;82 Suppl 3:1193-7. doi: 10.1016/j.fertnstert.2004.03.037. Fertil Steril. 2004. PMID: 15474095 Free article.
At the highest concentration (30 microM), mevastatin inhibited DNA synthesis by 92%. Similarly, in the MTT proliferation assay, mevastatin induced a concentration-dependent decrease in cell number. ...CONCLUSION(S): Mevastatin inhibits proliferation of theca- …
At the highest concentration (30 microM), mevastatin inhibited DNA synthesis by 92%. Similarly, in the MTT proliferation assay, me …
Mevastatin-Induced AP-1-Dependent HO-1 Expression Suppresses Vascular Cell Adhesion Molecule-1 Expression and Monocyte Adhesion on Human Pulmonary Alveolar Epithelial Cells Challenged with TNF-alpha.
Yang CM, Lin CC, Yang CC, Cho RL, Hsiao LD. Yang CM, et al. Biomolecules. 2020 Mar 1;10(3):381. doi: 10.3390/biom10030381. Biomolecules. 2020. PMID: 32121588 Free PMC article.
Mevastatin (MVS) has been previously shown to induce heme oxygenase (HO)-1 expression through Nox/ROS-dependent PDGFRalpha/PI3K/Akt/Nrf2/ARE axis in human pulmonary alveolar epithelial cells (HPAEpiCs). ...
Mevastatin (MVS) has been previously shown to induce heme oxygenase (HO)-1 expression through Nox/ROS-dependent PDGFRalpha/PI3K/Akt/N …
Mevastatin ameliorates sphingosine 1-phosphate-induced COX-2/PGE2-dependent cell migration via FoxO1 and CREB phosphorylation and translocation.
Hsu CK, Lin CC, Hsiao LD, Yang CM. Hsu CK, et al. Br J Pharmacol. 2015 Nov;172(22):5360-76. doi: 10.1111/bph.13326. Epub 2015 Oct 23. Br J Pharmacol. 2015. PMID: 26359950 Free PMC article.
However, the mechanisms underlying S1P-evoked COX-2-dependent cell migration, which is modulated by mevastatin in human tracheal smooth muscle cells (HTSMCs) remain unclear. ...Mevastatin could be beneficial for prevention of airway inflammation in the future....
However, the mechanisms underlying S1P-evoked COX-2-dependent cell migration, which is modulated by mevastatin in human tracheal smoo …
Mevastatin blockade of autolysosome maturation stimulates LBH589-induced cell death in triple-negative breast cancer cells.
Lin Z, Zhang Z, Jiang X, Kou X, Bao Y, Liu H, Sun F, Ling S, Qin N, Jiang L, Yang Y. Lin Z, et al. Oncotarget. 2017 Mar 14;8(11):17833-17848. doi: 10.18632/oncotarget.14868. Oncotarget. 2017. PMID: 28147319 Free PMC article.
Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, and combining a HDACi with other agents is an attractive therapeutic strategy in solid tumors. We report here that mevastatin increases HDACi LBH589-induced cell death in triple-negative breast cancer …
Histone deacetylase inhibitors (HDACi) are promising anti-cancer agents, and combining a HDACi with other agents is an attractive therapeuti …
Effects of Mycotoxin Fumagillin, Mevastatin, Radicicol, and Wortmannin on Photosynthesis of Chlamydomonas reinhardtii.
Shi J, Jiang M, Wang H, Luo Z, Guo Y, Chen Y, Zhao X, Qiang S, Strasser RJ, Kalaji HM, Chen S. Shi J, et al. Plants (Basel). 2023 Feb 2;12(3):665. doi: 10.3390/plants12030665. Plants (Basel). 2023. PMID: 36771749 Free PMC article.
Mycotoxins are one of the most important sources for the discovery of new pesticides and drugs because of their chemical structural diversity and fascinating bioactivity as well as unique novel targets. Here, the effects of four mycotoxins, fumagillin, mevastatin, radicico …
Mycotoxins are one of the most important sources for the discovery of new pesticides and drugs because of their chemical structural diversit …
617 results