Effect of transcranial magnetic stimulation as an enhancer of cognitive stimulation sessions on mild cognitive impairment: Preliminary results

Roque Roque Gy; Reyes-López Jv; Ricardo Garcell J; López Hidalgo M; Aguilar Fabré L; Trejo Cruz G; Cañizares Gómez S; Calderón Moctezuma Ar; Ortega Cruz F; Ortíz Baron A; Arias García Na; Espino Cortés M; Hernández Montiel H; González Olvera J

doi:10.1016/j.psychres.2021.114151

Effect of transcranial magnetic stimulation as an enhancer of cognitive stimulation sessions on mild cognitive impairment: Preliminary results

Psychiatry Res. 2021 Oct:304:114151. doi: 10.1016/j.psychres.2021.114151. Epub 2021 Aug 2.

Affiliations

¹ Universidad Autónoma de Querétaro, Facultad de Medicina. Laboratorio Multidisciplinario de, Investigación Biomédica Avanzada. Querétaro, México. Electronic address: georginaroqueroque@gmail.com.
² Universidad Autónoma de Querétaro, Facultad de Medicina. Laboratorio Multidisciplinario de, Investigación Biomédica Avanzada. Querétaro, México. Electronic address: opdeih@yahoo.com.
³ Instituto de Neurobiología UNAM, Campus Juriquilla, Querétaro, México.
⁴ Escuela Nacional de Estudios Superiores, Juriquilla, Universidad Autónoma de México, Campus, UNAM-Juriquilla, Querétaro, México.
⁵ Universidad Autónoma de Querétaro, Facultad de Medicina. Laboratorio Multidisciplinario de, Investigación Biomédica Avanzada. Querétaro, México.
⁶ Universidad del Valle de México, UVM, Campus Querétaro, México.
⁷ Centro Estatal de Salud Mental del Estado de Querétaro, México.
⁸ Comisión Nacional Contra las Adicciones, Ciudad de México, México.

PMID: 34392162
DOI: 10.1016/j.psychres.2021.114151

Abstract

Mild cognitive impairment (MCI) is a state between normal cognition and dementia. Currently, there is little evidence of repetitive Transcranial Magnetic Stimulation (rTMS) as an enhancing tool for Cognitive Stimulation (CS) on MCI. The importance of this study consists in its assessment of the enhancing effect of rTMS on CS in 22 MCI patients randomized and divided into two group: active (AG) and sham (SG). Diagnoses and assessments were determined during 30 sessions over a 10-week period by Montreal Cognitive Assessment (MoCA) and Neuropsí test. Results were statistically significant in the intergroup analysis with MoCA and intragroup only for AG.

Keywords: Cognitive stimulation; Mild cognitive impairment; Transcranial magnetic stimulation.

Publication types

Randomized Controlled Trial
Research Support, Non-U.S. Gov't

MeSH terms

Cognition
Cognitive Behavioral Therapy*
Cognitive Dysfunction* / therapy
Humans
Mental Status and Dementia Tests
Transcranial Magnetic Stimulation