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Items: 1 to 20 of 197

1.

Smoking is associated with aggravated kidney injury in Puumala hantavirus-induced haemorrhagic fever with renal syndrome.

Tervo L, Mäkelä S, Syrjänen J, Huttunen R, Rimpelä A, Huhtala H, Vapalahti O, Vaheri A, Mustonen J.

Nephrol Dial Transplant. 2015 Jul 5. pii: gfv273. [Epub ahead of print]

PMID:
26150428
2.

Community Acquired Severe Acute Kidney Injury Caused by Hantavirus-Induced Hemorrhagic Fever with Renal Syndrome Has a Favorable Outcome.

Outinen TK, Mäkelä S, Clement J, Paakkala A, Pörsti I, Mustonen J.

Nephron. 2015;130(3):182-90. doi: 10.1159/000433563. Epub 2015 Jun 26.

PMID:
26139246
3.

Weight gain and inflammation regulate aromatase expression in male adipose tissue, as evidenced by reporter gene activity.

Polari L, Yatkin E, Martínez Chacón MG, Ahotupa M, Smeds A, Strauss L, Zhang F, Poutanen M, Saarinen N, Mäkelä SI.

Mol Cell Endocrinol. 2015 Sep 5;412:123-30. doi: 10.1016/j.mce.2015.06.002. Epub 2015 Jun 6.

PMID:
26054748
4.

Network pharmacology applications to map the unexplored target space and therapeutic potential of natural products.

Kibble M, Saarinen N, Tang J, Wennerberg K, Mäkelä S, Aittokallio T.

Nat Prod Rep. 2015 Jul 22;32(8):1249-66. doi: 10.1039/c5np00005j.

PMID:
26030402
5.

Role of the endocannabinoid system in obesity induced by neuropeptide Y overexpression in noradrenergic neurons.

Vähätalo LH, Ruohonen ST, Mäkelä S, Ailanen L, Penttinen AM, Stormi T, Kauko T, Piscitelli F, Silvestri C, Savontaus E, Di Marzo V.

Nutr Diabetes. 2015 Apr 27;5:e151. doi: 10.1038/nutd.2015.1.

6.

Severe Puumala virus infection in a patient with a lymphoproliferative disease treated with icatibant.

Laine O, Leppänen I, Koskela S, Antonen J, Mäkelä S, Sinisalo M, Vaheri A, Mustonen J.

Infect Dis (Lond). 2015 Feb;47(2):107-11. doi: 10.3109/00365548.2014.969304. Epub 2014 Dec 12.

PMID:
25496418
7.

Neuropeptide Y in the noradrenergic neurones induces obesity and inhibits sympathetic tone in mice.

Vähätalo LH, Ruohonen ST, Mäkelä S, Kovalainen M, Huotari A, Mäkelä KA, Määttä JA, Miinalainen I, Gilsbach R, Hein L, Ailanen L, Mattila M, Eerola K, Röyttä M, Ruohonen S, Herzig KH, Savontaus E.

Acta Physiol (Oxf). 2015 Apr;213(4):902-19. doi: 10.1111/apha.12436. Epub 2014 Dec 26.

PMID:
25482272
8.

Efficient replication and strong induction of innate immune responses by H9N2 avian influenza virus in human dendritic cells.

Westenius V, Mäkelä SM, Ziegler T, Julkunen I, Österlund P.

Virology. 2014 Dec;471-473:38-48. doi: 10.1016/j.virol.2014.10.002. Epub 2014 Oct 25.

PMID:
25461529
9.

Pathophysiology of a severe case of Puumala hantavirus infection successfully treated with bradykinin receptor antagonist icatibant.

Vaheri A, Strandin T, Jääskeläinen AJ, Vapalahti O, Jarva H, Lokki ML, Antonen J, Leppänen I, Mäkelä S, Meri S, Mustonen J.

Antiviral Res. 2014 Nov;111:23-5. doi: 10.1016/j.antiviral.2014.08.007. Epub 2014 Sep 3.

PMID:
25194993
10.

Spleen enlargement is a common finding in acute Puumala hantavirus infection and it does not associate with thrombocytopenia.

Koskela SM, Laine OK, Paakkala AS, Mäkelä SM, Mustonen JT.

Scand J Infect Dis. 2014 Oct;46(10):723-6. doi: 10.3109/00365548.2014.930967. Epub 2014 Aug 14.

PMID:
25119440
11.

Dynamin inhibition interferes with inflammasome activation and cytokine gene expression in Streptococcus pyogenes-infected human macrophages.

Latvala S, Mäkelä SM, Miettinen M, Charpentier E, Julkunen I.

Clin Exp Immunol. 2014 Nov;178(2):320-33. doi: 10.1111/cei.12425.

PMID:
25079511
12.

Acute hantavirus infection induces galectin-3-binding protein.

Hepojoki J, Strandin T, Hetzel U, Sironen T, Klingström J, Sane J, Mäkelä S, Mustonen J, Meri S, Lundkvist A, Vapalahti O, Lankinen H, Vaheri A.

J Gen Virol. 2014 Nov;95(Pt 11):2356-64. doi: 10.1099/vir.0.066837-0. Epub 2014 Jul 10.

PMID:
25013204
13.

Castration induces up-regulation of intratumoral androgen biosynthesis and androgen receptor expression in an orthotopic VCaP human prostate cancer xenograft model.

Knuuttila M, Yatkin E, Kallio J, Savolainen S, Laajala TD, Aittokallio T, Oksala R, Häkkinen M, Keski-Rahkonen P, Auriola S, Poutanen M, Mäkelä S.

Am J Pathol. 2014 Aug;184(8):2163-73. doi: 10.1016/j.ajpath.2014.04.010. Epub 2014 Jun 17.

14.

Deficiency of ERβ and prostate tumorigenesis in FGF8b transgenic mice.

Elo T, Yu L, Valve E, Mäkelä S, Härkönen P.

Endocr Relat Cancer. 2014 Aug;21(4):677-90. doi: 10.1530/ERC-13-0480. Epub 2014 Jun 17.

15.

Novel avian influenza A (H7N9) virus induces impaired interferon responses in human dendritic cells.

Arilahti V, Mäkelä SM, Tynell J, Julkunen I, Österlund P.

PLoS One. 2014 May 7;9(5):e96350. doi: 10.1371/journal.pone.0096350. eCollection 2014.

16.

Plasma pentraxin-3 and coagulation and fibrinolysis variables during acute Puumala hantavirus infection and associated thrombocytopenia.

Laine OK, Koskela SM, Outinen TK, Joutsi-Korhonen L, Huhtala H, Vaheri A, Hurme MA, Jylhävä J, Mäkelä SM, Mustonen JT.

Blood Coagul Fibrinolysis. 2014 Sep;25(6):612-7. doi: 10.1097/MBC.0000000000000117.

PMID:
24751477
17.

Urine soluble urokinase-type plasminogen activator receptor levels correlate with proteinuria in Puumala hantavirus infection.

Outinen TK, Mäkelä S, Huttunen R, Mäenpää N, Libraty D, Vaheri A, Mustonen J, Aittoniemi J.

J Intern Med. 2014 Oct;276(4):387-95. doi: 10.1111/joim.12257. Epub 2014 May 14.

PMID:
24717117
18.

Novel Lignan and stilbenoid mixture shows anticarcinogenic efficacy in preclinical PC-3M-luc2 prostate cancer model.

Yatkin E, Polari L, Laajala TD, Smeds A, Eckerman C, Holmbom B, Saarinen NM, Aittokallio T, Mäkelä SI.

PLoS One. 2014 Apr 3;9(4):e93764. doi: 10.1371/journal.pone.0093764. eCollection 2014.

19.

Adenine phosphoribosyltransferase deficiency as a rare cause of renal allograft dysfunction.

Kaartinen K, Hemmilä U, Salmela K, Räisänen-Sokolowski A, Kouri T, Mäkelä S.

J Am Soc Nephrol. 2014 Apr;25(4):671-4. doi: 10.1681/ASN.2013090960. Epub 2014 Jan 23.

20.

Regulatory T cell response correlates with the severity of human hantavirus infection.

Koivula TT, Tuulasvaara A, Hetemäki I, Mäkelä SM, Mustonen J, Sironen T, Vaheri A, Arstila TP.

J Infect. 2014 Apr;68(4):387-94. doi: 10.1016/j.jinf.2013.11.007. Epub 2013 Nov 21.

PMID:
24269676
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