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The APOE Gene is Differentially Methylated in Alzheimer's Disease.

Foraker J, Millard SP, Leong L, Thomson Z, Chen S, Keene CD, Bekris LM, Yu CE.

J Alzheimers Dis. 2015;48(3):745-55. doi: 10.3233/JAD-143060.


Cerebrospinal fluid Aβ42 levels and APP processing pathway genes in Parkinson's disease.

Bekris LM, Tsuang DW, Peskind ER, Yu CE, Montine TJ, Zhang J, Zabetian CP, Leverenz JB.

Mov Disord. 2015 Jun;30(7):936-44. doi: 10.1002/mds.26172. Epub 2015 Mar 24.


The biomarker and therapeutic potential of miRNA in Alzheimer's disease.

Bekris LM, Leverenz JB.

Neurodegener Dis Manag. 2015;5(1):61-74. doi: 10.2217/nmt.14.52. Review.


Association of cerebrospinal fluid Aβ42 with A2M gene in cognitively normal subjects.

Millard SP, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang D, Yu CE, Peskind ER, Bekris LM.

Neurobiol Aging. 2014 Feb;35(2):357-64. doi: 10.1016/j.neurobiolaging.2013.07.027. Epub 2013 Sep 4.


Epigenetic signature and enhancer activity of the human APOE gene.

Yu CE, Cudaback E, Foraker J, Thomson Z, Leong L, Lutz F, Gill JA, Saxton A, Kraemer B, Navas P, Keene CD, Montine T, Bekris LM.

Hum Mol Genet. 2013 Dec 15;22(24):5036-47. doi: 10.1093/hmg/ddt354. Epub 2013 Jul 25.


MicroRNA in Alzheimer's disease: an exploratory study in brain, cerebrospinal fluid and plasma.

Bekris LM, Lutz F, Montine TJ, Yu CE, Tsuang D, Peskind ER, Leverenz JB.

Biomarkers. 2013 Aug;18(5):455-66. doi: 10.3109/1354750X.2013.814073. Epub 2013 Jul 3.


TOMM40 intron 6 poly-T length, age at onset, and neuropathology of AD in individuals with APOE ε3/ε3.

Li G, Bekris LM, Leong L, Steinbart EJ, Shofer JB, Crane PK, Larson EB, Peskind ER, Bird TD, Yu CE.

Alzheimers Dement. 2013 Sep;9(5):554-61. doi: 10.1016/j.jalz.2012.06.009. Epub 2012 Nov 22.


Tau phosphorylation pathway genes and cerebrospinal fluid tau levels in Alzheimer's disease.

Bekris LM, Millard S, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang DW, Yu CE, Peskind ER.

Am J Med Genet B Neuropsychiatr Genet. 2012 Oct;159B(7):874-83. doi: 10.1002/ajmg.b.32094. Epub 2012 Aug 27.


ADAM10 expression and promoter haplotype in Alzheimer's disease.

Bekris LM, Lutz F, Li G, Galasko DR, Farlow MR, Quinn JF, Kaye JA, Leverenz JB, Tsuang DW, Montine TJ, Peskind ER, Yu CE.

Neurobiol Aging. 2012 Sep;33(9):2229.e1-2229.e9. doi: 10.1016/j.neurobiolaging.2012.03.013. Epub 2012 May 8.


Differential expression of the glutamate transporter GLT-1 in pancreas.

Meabon JS, Lee A, Meeker KD, Bekris LM, Fujimura RK, Yu CE, Watson GS, Pow DV, Sweet IR, Cook DG.

J Histochem Cytochem. 2012 Feb;60(2):139-51. doi: 10.1369/0022155411430095. Epub 2011 Nov 22.


Functional analysis of APOE locus genetic variation implicates regional enhancers in the regulation of both TOMM40 and APOE.

Bekris LM, Lutz F, Yu CE.

J Hum Genet. 2012 Jan;57(1):18-25. doi: 10.1038/jhg.2011.123. Epub 2011 Nov 17.


Genetics of Alzheimer disease.

Bekris LM, Yu CE, Bird TD, Tsuang DW.

J Geriatr Psychiatry Neurol. 2010 Dec;23(4):213-27. doi: 10.1177/0891988710383571. Review.


The genetics of Parkinson disease.

Bekris LM, Mata IF, Zabetian CP.

J Geriatr Psychiatry Neurol. 2010 Dec;23(4):228-42. doi: 10.1177/0891988710383572. Epub 2010 Oct 11. Review.


The spectrum of mutations in progranulin: a collaborative study screening 545 cases of neurodegeneration.

Yu CE, Bird TD, Bekris LM, Montine TJ, Leverenz JB, Steinbart E, Galloway NM, Feldman H, Woltjer R, Miller CA, Wood EM, Grossman M, McCluskey L, Clark CM, Neumann M, Danek A, Galasko DR, Arnold SE, Chen-Plotkin A, Karydas A, Miller BL, Trojanowski JQ, Lee VM, Schellenberg GD, Van Deerlin VM.

Arch Neurol. 2010 Feb;67(2):161-70. doi: 10.1001/archneurol.2009.328.


APOE mRNA and protein expression in postmortem brain are modulated by an extended haplotype structure.

Bekris LM, Galloway NM, Montine TJ, Schellenberg GD, Yu CE.

Am J Med Genet B Neuropsychiatr Genet. 2010 Mar 5;153B(2):409-17. doi: 10.1002/ajmg.b.30993.


Cerebrospinal fluid concentration of brain-derived neurotrophic factor and cognitive function in non-demented subjects.

Li G, Peskind ER, Millard SP, Chi P, Sokal I, Yu CE, Bekris LM, Raskind MA, Galasko DR, Montine TJ.

PLoS One. 2009;4(5):e5424. doi: 10.1371/journal.pone.0005424. Epub 2009 May 1.


Multiple SNPs within and surrounding the apolipoprotein E gene influence cerebrospinal fluid apolipoprotein E protein levels.

Bekris LM, Millard SP, Galloway NM, Vuletic S, Albers JJ, Li G, Galasko DR, DeCarli C, Farlow MR, Clark CM, Quinn JF, Kaye JA, Schellenberg GD, Tsuang D, Peskind ER, Yu CE.

J Alzheimers Dis. 2008 Apr;13(3):255-66.


TARDBP mutations in amyotrophic lateral sclerosis with TDP-43 neuropathology: a genetic and histopathological analysis.

Van Deerlin VM, Leverenz JB, Bekris LM, Bird TD, Yuan W, Elman LB, Clay D, Wood EM, Chen-Plotkin AS, Martinez-Lage M, Steinbart E, McCluskey L, Grossman M, Neumann M, Wu IL, Yang WS, Kalb R, Galasko DR, Montine TJ, Trojanowski JQ, Lee VM, Schellenberg GD, Yu CE.

Lancet Neurol. 2008 May;7(5):409-16. doi: 10.1016/S1474-4422(08)70071-1. Epub 2008 Apr 7.


Antibodies to GAD65 and peripheral nerve function in the DCCT.

Hoeldtke RD, Hampe CS, Bekris LM, Hobbs G, Bryner KD, Lernmark A; DCCT Research Group.

J Neuroimmunol. 2007 Apr;185(1-2):182-9. Epub 2007 Feb 27.


Genetic mapping at 3-kilobase resolution reveals inositol 1,4,5-triphosphate receptor 3 as a risk factor for type 1 diabetes in Sweden.

Roach JC, Deutsch K, Li S, Siegel AF, Bekris LM, Einhaus DC, Sheridan CM, Glusman G, Hood L, Lernmark A, Janer M; Swedish Childhood Diabetes Study Group; Diabetes Incidence in Sweden Study Group.

Am J Hum Genet. 2006 Oct;79(4):614-27. Epub 2006 Aug 30.

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