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Results: 1 to 20 of 40

1.

HES5 silencing is an early and recurrent change in prostate tumourigenesis.

Massie CE, Spiteri I, Ross-Adams H, Luxton H, Kay J, Whitaker HC, Dunning MJ, Lamb AD, Ramos-Montoya A, Brewer DS, Cooper CS, Eeles R, Warren AY, Tavaré S, Neal DE, Lynch AG.

Endocr Relat Cancer. 2015 Jan 5. pii: ERC-14-0454. [Epub ahead of print]

PMID:
25560400
[PubMed - as supplied by publisher]
2.

Quantifying the impact of inter-site heterogeneity on the distribution of ChIP-seq data.

Cairns J, Lynch AG, Tavaré S.

Front Genet. 2014 Nov 14;5:399. doi: 10.3389/fgene.2014.00399. eCollection 2014.

PMID:
25452765
[PubMed]
Free PMC Article
3.

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer.

Ju YS, Alexandrov LB, Gerstung M, Martincorena I, Nik-Zainal S, Ramakrishna M, Davies HR, Papaemmanuil E, Gundem G, Shlien A, Bolli N, Behjati S, Tarpey PS, Nangalia J, Massie CE, Butler AP, Teague JW, Vassiliou GS, Green AR, Du MQ, Unnikrishnan A, Pimanda JE, Teh BT, Munshi N, Greaves M, Vyas P, El-Naggar AK, Santarius T, Collins VP, Grundy R, Taylor JA, Hayes DN, Malkin D; ICGC Breast Cancer Group; ICGC Chronic Myeloid Disorders Group; ICGC Prostate Cancer Group, Foster CS, Warren AY, Whitaker HC, Brewer D, Eeles R, Cooper C, Neal D, Visakorpi T, Isaacs WB, Bova GS, Flanagan AM, Futreal PA, Lynch AG, Chinnery PF, McDermott U, Stratton MR, Campbell PJ.

Elife. 2014 Oct 1;3. doi: 10.7554/eLife.02935.

PMID:
25271376
[PubMed - in process]
Free Article
4.

Mobile DNA in cancer. Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes.

Tubio JM, Li Y, Ju YS, Martincorena I, Cooke SL, Tojo M, Gundem G, Pipinikas CP, Zamora J, Raine K, Menzies A, Roman-Garcia P, Fullam A, Gerstung M, Shlien A, Tarpey PS, Papaemmanuil E, Knappskog S, Van Loo P, Ramakrishna M, Davies HR, Marshall J, Wedge DC, Teague JW, Butler AP, Nik-Zainal S, Alexandrov L, Behjati S, Yates LR, Bolli N, Mudie L, Hardy C, Martin S, McLaren S, O'Meara S, Anderson E, Maddison M, Gamble S; ICGC Breast Cancer Group; ICGC Bone Cancer Group; ICGC Prostate Cancer Group, Foster C, Warren AY, Whitaker H, Brewer D, Eeles R, Cooper C, Neal D, Lynch AG, Visakorpi T, Isaacs WB, van't Veer L, Caldas C, Desmedt C, Sotiriou C, Aparicio S, Foekens JA, Eyfjörd JE, Lakhani SR, Thomas G, Myklebost O, Span PN, Børresen-Dale AL, Richardson AL, Van de Vijver M, Vincent-Salomon A, Van den Eynden GG, Flanagan AM, Futreal PA, Janes SM, Bova GS, Stratton MR, McDermott U, Campbell PJ.

Science. 2014 Aug 1;345(6196):1251343. doi: 10.1126/science.1251343.

PMID:
25082706
[PubMed - indexed for MEDLINE]
5.

Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis.

Weaver JM, Ross-Innes CS, Shannon N, Lynch AG, Forshew T, Barbera M, Murtaza M, Ong CA, Lao-Sirieix P, Dunning MJ, Smith L, Smith ML, Anderson CL, Carvalho B, O'Donovan M, Underwood TJ, May AP, Grehan N, Hardwick R, Davies J, Oloumi A, Aparicio S, Caldas C, Eldridge MD, Edwards PA, Rosenfeld N, Tavaré S, Fitzgerald RC; OCCAMS Consortium.

Nat Genet. 2014 Aug;46(8):837-43. doi: 10.1038/ng.3013. Epub 2014 Jun 22.

PMID:
24952744
[PubMed - indexed for MEDLINE]
6.

Peroxiredoxin-3 is overexpressed in prostate cancer and promotes cancer cell survival by protecting cells from oxidative stress.

Whitaker HC, Patel D, Howat WJ, Warren AY, Kay JD, Sangan T, Marioni JC, Mitchell J, Aldridge S, Luxton HJ, Massie C, Lynch AG, Neal DE.

Br J Cancer. 2013 Aug 20;109(4):983-93. doi: 10.1038/bjc.2013.396. Epub 2013 Jul 23.

PMID:
23880827
[PubMed - indexed for MEDLINE]
Free PMC Article
7.

Variability of computational fluid dynamics solutions for pressure and flow in a giant aneurysm: the ASME 2012 Summer Bioengineering Conference CFD Challenge.

Steinman DA, Hoi Y, Fahy P, Morris L, Walsh MT, Aristokleous N, Anayiotos AS, Papaharilaou Y, Arzani A, Shadden SC, Berg P, Janiga G, Bols J, Segers P, Bressloff NW, Cibis M, Gijsen FH, Cito S, Pallarés J, Browne LD, Costelloe JA, Lynch AG, Degroote J, Vierendeels J, Fu W, Qiao A, Hodis S, Kallmes DF, Kalsi H, Long Q, Kheyfets VO, Finol EA, Kono K, Malek AM, Lauric A, Menon PG, Pekkan K, Esmaily Moghadam M, Marsden AL, Oshima M, Katagiri K, Peiffer V, Mohamied Y, Sherwin SJ, Schaller J, Goubergrits L, Usera G, Mendina M, Valen-Sendstad K, Habets DF, Xiang J, Meng H, Yu Y, Karniadakis GE, Shaffer N, Loth F.

J Biomech Eng. 2013 Feb;135(2):021016. doi: 10.1115/1.4023382.

PMID:
23445061
[PubMed - indexed for MEDLINE]
8.

Calling sample mix-ups in cancer population studies.

Lynch AG, Chin SF, Dunning MJ, Caldas C, Tavaré S, Curtis C.

PLoS One. 2012;7(8):e41815. doi: 10.1371/journal.pone.0041815. Epub 2012 Aug 9.

PMID:
22912679
[PubMed - indexed for MEDLINE]
Free PMC Article
9.

The genomic and transcriptomic architecture of 2,000 breast tumours reveals novel subgroups.

Curtis C, Shah SP, Chin SF, Turashvili G, Rueda OM, Dunning MJ, Speed D, Lynch AG, Samarajiwa S, Yuan Y, Gräf S, Ha G, Haffari G, Bashashati A, Russell R, McKinney S; METABRIC Group, Langerød A, Green A, Provenzano E, Wishart G, Pinder S, Watson P, Markowetz F, Murphy L, Ellis I, Purushotham A, Børresen-Dale AL, Brenton JD, Tavaré S, Caldas C, Aparicio S.

Nature. 2012 Apr 18;486(7403):346-52. doi: 10.1038/nature10983.

PMID:
22522925
[PubMed - indexed for MEDLINE]
Free PMC Article
10.

BeadArray expression analysis using bioconductor.

Ritchie ME, Dunning MJ, Smith ML, Shi W, Lynch AG.

PLoS Comput Biol. 2011 Dec;7(12):e1002276. doi: 10.1371/journal.pcbi.1002276. Epub 2011 Dec 1.

PMID:
22144879
[PubMed - indexed for MEDLINE]
Free PMC Article
11.

ZNF703 is a common Luminal B breast cancer oncogene that differentially regulates luminal and basal progenitors in human mammary epithelium.

Holland DG, Burleigh A, Git A, Goldgraben MA, Perez-Mancera PA, Chin SF, Hurtado A, Bruna A, Ali HR, Greenwood W, Dunning MJ, Samarajiwa S, Menon S, Rueda OM, Lynch AG, McKinney S, Ellis IO, Eaves CJ, Carroll JS, Curtis C, Aparicio S, Caldas C.

EMBO Mol Med. 2011 Mar;3(3):167-80. doi: 10.1002/emmm.201100122. Epub 2011 Feb 18.

PMID:
21337521
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

BayesPeak--an R package for analysing ChIP-seq data.

Cairns J, Spyrou C, Stark R, Smith ML, Lynch AG, Tavaré S.

Bioinformatics. 2011 Mar 1;27(5):713-4. doi: 10.1093/bioinformatics/btq685. Epub 2011 Jan 17.

PMID:
21245054
[PubMed - indexed for MEDLINE]
Free PMC Article
13.
14.

The cost of reducing starting RNA quantity for Illumina BeadArrays: a bead-level dilution experiment.

Lynch AG, Hadfield J, Dunning MJ, Osborne M, Thorne NP, Tavaré S.

BMC Genomics. 2010 Oct 6;11:540. doi: 10.1186/1471-2164-11-540.

PMID:
20925945
[PubMed - indexed for MEDLINE]
Free PMC Article
15.

The importance of platform annotation in interpreting microarray data.

Dunning MJ, Curtis C, Barbosa-Morais NL, Caldas C, Tavaré S, Lynch AG.

Lancet Oncol. 2010 Aug;11(8):717. doi: 10.1016/S1470-2045(10)70115-7. No abstract available.

PMID:
20688273
[PubMed - indexed for MEDLINE]
16.

Identification and correction of previously unreported spatial phenomena using raw Illumina BeadArray data.

Smith ML, Dunning MJ, Tavaré S, Lynch AG.

BMC Bioinformatics. 2010 Apr 27;11:208. doi: 10.1186/1471-2105-11-208.

PMID:
20423502
[PubMed - indexed for MEDLINE]
Free PMC Article
17.

Use of the piggyBac transposon to create HIV-1 gag transgenic insect cell lines for continuous VLP production.

Lynch AG, Tanzer F, Fraser MJ, Shephard EG, Williamson AL, Rybicki EP.

BMC Biotechnol. 2010 Mar 31;10:30. doi: 10.1186/1472-6750-10-30.

PMID:
20356379
[PubMed - indexed for MEDLINE]
Free PMC Article
18.

Driver mutations in TP53 are ubiquitous in high grade serous carcinoma of the ovary.

Ahmed AA, Etemadmoghadam D, Temple J, Lynch AG, Riad M, Sharma R, Stewart C, Fereday S, Caldas C, Defazio A, Bowtell D, Brenton JD.

J Pathol. 2010 May;221(1):49-56. doi: 10.1002/path.2696.

PMID:
20229506
[PubMed - indexed for MEDLINE]
Free PMC Article
19.

The pitfalls of platform comparison: DNA copy number array technologies assessed.

Curtis C, Lynch AG, Dunning MJ, Spiteri I, Marioni JC, Hadfield J, Chin SF, Brenton JD, Tavaré S, Caldas C.

BMC Genomics. 2009 Dec 8;10:588. doi: 10.1186/1471-2164-10-588.

PMID:
19995423
[PubMed - indexed for MEDLINE]
Free PMC Article
20.

A re-annotation pipeline for Illumina BeadArrays: improving the interpretation of gene expression data.

Barbosa-Morais NL, Dunning MJ, Samarajiwa SA, Darot JF, Ritchie ME, Lynch AG, Tavaré S.

Nucleic Acids Res. 2010 Jan;38(3):e17. doi: 10.1093/nar/gkp942. Epub 2009 Nov 18.

PMID:
19923232
[PubMed - indexed for MEDLINE]
Free PMC Article

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