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Results: 1 to 20 of 520

1.

ABCC6 deficiency is associated with activation of BMP signaling in liver and kidney.

Blazquez-Medela AM, Guihard PJ, Yao J, Jumabay M, Lusis AJ, Boström KI, Yao Y.

FEBS Open Bio. 2015 Mar 23;5:257-63. doi: 10.1016/j.fob.2015.03.009. eCollection 2015.

2.

Future Translational Applications From the Contemporary Genomics Era: A Scientific Statement From the American Heart Association.

Fox CS, Hall JL, Arnett DK, Ashley EA, Delles C, Engler MB, Freeman MW, Johnson JA, Lanfear DE, Liggett SB, Lusis AJ, Loscalzo J, MacRae CA, Musunuru K, Newby LK, O'Donnell CJ, Rich SS, Terzic A.

Circulation. 2015 Apr 16. pii: CIR.0000000000000211. [Epub ahead of print]

PMID:
25882488
3.

Genome-wide association study identifies nox3 as a critical gene for susceptibility to noise-induced hearing loss.

Lavinsky J, Crow AL, Pan C, Wang J, Aaron KA, Ho MK, Li Q, Salehide P, Myint A, Monges-Hernadez M, Eskin E, Allayee H, Lusis AJ, Friedman RA.

PLoS Genet. 2015 Apr 16;11(4):e1005094. doi: 10.1371/journal.pgen.1005094. eCollection 2015 Apr.

4.

Genetics of common forms of heart failure: challenges and potential solutions.

Rau CD, Lusis AJ, Wang Y.

Curr Opin Cardiol. 2015 May;30(3):222-7. doi: 10.1097/HCO.0000000000000160.

PMID:
25768955
5.

Combined QTL and Selective Sweep Mappings with Coding SNP Annotation and cis-eQTL Analysis Revealed PARK2 and JAG2 as New Candidate Genes for Adiposity Regulation.

Roux PF, Boitard S, Blum Y, Parks B, Montagner A, Mouisel E, Djari A, Esquerré D, Désert C, Boutin M, Leroux S, Lecerf F, Le Bihan-Duval E, Klopp C, Servin B, Pitel F, Duclos MJ, Guillou H, Lusis AJ, Demeure O, Lagarrigue S.

G3 (Bethesda). 2015 Feb 3;5(4):517-29. doi: 10.1534/g3.115.016865.

6.

Genetic architecture of insulin resistance in the mouse.

Parks BW, Sallam T, Mehrabian M, Psychogios N, Hui ST, Norheim F, Castellani LW, Rau CD, Pan C, Phun J, Zhou Z, Yang WP, Neuhaus I, Gargalovic PS, Kirchgessner TG, Graham M, Lee R, Tontonoz P, Gerszten RE, Hevener AL, Lusis AJ.

Cell Metab. 2015 Feb 3;21(2):334-46. doi: 10.1016/j.cmet.2015.01.002.

PMID:
25651185
7.

The TMAO-Generating Enzyme Flavin Monooxygenase 3 Is a Central Regulator of Cholesterol Balance.

Warrier M, Shih DM, Burrows AC, Ferguson D, Gromovsky AD, Brown AL, Marshall S, McDaniel A, Schugar RC, Wang Z, Sacks J, Rong X, Vallim TA, Chou J, Ivanova PT, Myers DS, Brown HA, Lee RG, Crooke RM, Graham MJ, Liu X, Parini P, Tontonoz P, Lusis AJ, Hazen SL, Temel RE, Brown JM.

Cell Rep. 2015 Jan 14. pii: S2211-1247(14)01065-1. doi: 10.1016/j.celrep.2014.12.036. [Epub ahead of print]

8.

Heritability of periodontal bone loss in mice.

Hiyari S, Atti E, Camargo PM, Eskin E, Lusis AJ, Tetradis S, Pirih FQ.

J Periodontal Res. 2015 Jan 12. doi: 10.1111/jre.12258. [Epub ahead of print]

PMID:
25581386
9.

Transmission of atherosclerosis susceptibility with gut microbial transplantation.

Gregory JC, Buffa JA, Org E, Wang Z, Levison BS, Zhu W, Wagner MA, Bennett BJ, Li L, DiDonato JA, Lusis AJ, Hazen SL.

J Biol Chem. 2015 Feb 27;290(9):5647-60. doi: 10.1074/jbc.M114.618249. Epub 2014 Dec 30.

PMID:
25550161
10.

Mapping genetic contributions to cardiac pathology induced by Beta-adrenergic stimulation in mice.

Rau CD, Wang J, Avetisyan R, Romay MC, Martin L, Ren S, Wang Y, Lusis AJ.

Circ Cardiovasc Genet. 2015 Feb;8(1):40-9. doi: 10.1161/CIRCGENETICS.113.000732. Epub 2014 Dec 5.

PMID:
25480693
11.

PON3 knockout mice are susceptible to obesity, gallstone formation, and atherosclerosis.

Shih DM, Yu JM, Vergnes L, Dali-Youcef N, Champion MD, Devarajan A, Zhang P, Castellani LW, Brindley DN, Jamey C, Auwerx J, Reddy ST, Ford DA, Reue K, Lusis AJ.

FASEB J. 2015 Apr;29(4):1185-97. doi: 10.1096/fj.14-260570. Epub 2014 Dec 4.

PMID:
25477283
12.

Estrogen receptor (ER)α-regulated lipocalin 2 expression in adipose tissue links obesity with breast cancer progression.

Drew BG, Hamidi H, Zhou Z, Villanueva CJ, Krum SA, Calkin AC, Parks BW, Ribas V, Kalajian NY, Phun J, Daraei P, Christofk HR, Hewitt SC, Korach KS, Tontonoz P, Lusis AJ, Slamon DJ, Hurvitz SA, Hevener AL.

J Biol Chem. 2015 Feb 27;290(9):5566-81. doi: 10.1074/jbc.M114.606459. Epub 2014 Dec 2.

PMID:
25468909
13.

Reducing macrophage proteoglycan sulfation increases atherosclerosis and obesity through enhanced type I interferon signaling.

Gordts PL, Foley EM, Lawrence R, Sinha R, Lameda-Diaz C, Deng L, Nock R, Glass CK, Erbilgin A, Lusis AJ, Witztum JL, Esko JD.

Cell Metab. 2014 Nov 4;20(5):813-26. doi: 10.1016/j.cmet.2014.09.016. Epub 2014 Nov 4.

PMID:
25440058
14.

γ-Butyrobetaine is a proatherogenic intermediate in gut microbial metabolism of L-carnitine to TMAO.

Koeth RA, Levison BS, Culley MK, Buffa JA, Wang Z, Gregory JC, Org E, Wu Y, Li L, Smith JD, Tang WH, DiDonato JA, Lusis AJ, Hazen SL.

Cell Metab. 2014 Nov 4;20(5):799-812. doi: 10.1016/j.cmet.2014.10.006. Epub 2014 Nov 4.

PMID:
25440057
15.

Genetic modulation of diabetic nephropathy among mouse strains with Ins2 Akita mutation.

Wu X, Davis RC, McMillen TS, Schaeffer V, Zhou Z, Qi H, Mazandarani PN, Alialy R, Hudkins KL, Lusis AJ, LeBoeuf RC.

Physiol Rep. 2014 Nov 26;2(11). pii: e12208. doi: 10.14814/phy2.12208. Print 2014 Nov 1.

16.

Macrophage polarization phenotype regulates adiponectin receptor expression and adiponectin anti-inflammatory response.

van Stijn CM, Kim J, Lusis AJ, Barish GD, Tangirala RK.

FASEB J. 2015 Feb;29(2):636-49. doi: 10.1096/fj.14-253831. Epub 2014 Nov 12.

PMID:
25392268
17.

Flavin containing monooxygenase 3 exerts broad effects on glucose and lipid metabolism and atherosclerosis.

Shih DM, Wang Z, Lee R, Meng Y, Che N, Charugundla S, Qi H, Wu J, Pan C, Brown JM, Vallim T, Bennett BJ, Graham M, Hazen SL, Lusis AJ.

J Lipid Res. 2015 Jan;56(1):22-37. doi: 10.1194/jlr.M051680. Epub 2014 Nov 6.

PMID:
25378658
18.

Shared molecular pathways and gene networks for cardiovascular disease and type 2 diabetes mellitus in women across diverse ethnicities.

Chan KH, Huang YT, Meng Q, Wu C, Reiner A, Sobel EM, Tinker L, Lusis AJ, Yang X, Liu S.

Circ Cardiovasc Genet. 2014 Dec;7(6):911-9. doi: 10.1161/CIRCGENETICS.114.000676. Epub 2014 Nov 4.

PMID:
25371518
19.

Regulation of NF-κB signaling by oxidized glycerophospholipid and IL-1β induced miRs-21-3p and -27a-5p in human aortic endothelial cells.

Romay MC, Che N, Becker SN, Pouldar D, Hagopian R, Xiao X, Lusis AJ, Berliner JA, Civelek M.

J Lipid Res. 2015 Jan;56(1):38-50. doi: 10.1194/jlr.M052670. Epub 2014 Oct 19.

PMID:
25327529
20.

From hairballs to an understanding of transendothelial migration of monocytes in atherosclerosis.

Civelek M, Lusis AJ.

Arterioscler Thromb Vasc Biol. 2014 Sep;34(9):1809-10. doi: 10.1161/ATVBAHA.114.304151. No abstract available.

PMID:
25142882
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