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The TULIP superfamily of eukaryotic lipid-binding proteins as a mediator of lipid sensing and transport.

Alva V, Lupas AN.

Biochim Biophys Acta. 2016 Jan 26. pii: S1388-1981(16)30015-4. doi: 10.1016/j.bbalip.2016.01.016. [Epub ahead of print] Review.


α/β coiled coils.

Hartmann MD, Mendler CT, Bassler J, Karamichali I, Ridderbusch O, Lupas AN, Hernandez Alvarez B.

Elife. 2016 Jan 15;5. pii: e11861. doi: 10.7554/eLife.11861.


Structural Basis for Toughness and Flexibility in the C-terminal Passenger Domain of an Acinetobacter Trimeric Autotransporter Adhesin.

Koiwai K, Hartmann MD, Linke D, Lupas AN, Hori K.

J Biol Chem. 2016 Feb 19;291(8):3705-24. doi: 10.1074/jbc.M115.701698. Epub 2015 Dec 23.


A vocabulary of ancient peptides at the origin of folded proteins.

Alva V, Söding J, Lupas AN.

Elife. 2015 Dec 14;4:e09410. doi: 10.7554/eLife.09410.


Some of the most interesting CASP11 targets through the eyes of their authors.

Kryshtafovych A, Moult J, Baslé A, Burgin A, Craig TK, Edwards RA, Fass D, Hartmann MD, Korycinski M, Lewis RJ, Lorimer D, Lupas AN, Newman J, Peat TS, Piepenbrink KH, Prahlad J, van Raaij MJ, Rohwer F, Segall AM, Seguritan V, Sundberg EJ, Singh AK, Wilson MA, Schwede T.

Proteins. 2015 Oct 16. doi: 10.1002/prot.24942. [Epub ahead of print]


STAC--A New Domain Associated with Transmembrane Solute Transport and Two-Component Signal Transduction Systems.

Korycinski M, Albrecht R, Ursinus A, Hartmann MD, Coles M, Martin J, Dunin-Horkawicz S, Lupas AN.

J Mol Biol. 2015 Oct 9;427(20):3327-39. doi: 10.1016/j.jmb.2015.08.017. Epub 2015 Aug 28.


Structural dynamics of the cereblon ligand binding domain.

Hartmann MD, Boichenko I, Coles M, Lupas AN, Hernandez Alvarez B.

PLoS One. 2015 May 29;10(5):e0128342. doi: 10.1371/journal.pone.0128342. eCollection 2015.


A domain dictionary of trimeric autotransporter adhesins.

Bassler J, Hernandez Alvarez B, Hartmann MD, Lupas AN.

Int J Med Microbiol. 2015 Feb;305(2):265-75. doi: 10.1016/j.ijmm.2014.12.010. Epub 2014 Dec 24. Review.


Structure and evolution of N-domains in AAA metalloproteases.

Scharfenberg F, Serek-Heuberger J, Coles M, Hartmann MD, Habeck M, Martin J, Lupas AN, Alva V.

J Mol Biol. 2015 Feb 27;427(4):910-23. doi: 10.1016/j.jmb.2014.12.024. Epub 2015 Jan 8.


The thalidomide-binding domain of cereblon defines the CULT domain family and is a new member of the β-tent fold.

Lupas AN, Zhu H, Korycinski M.

PLoS Comput Biol. 2015 Jan 8;11(1):e1004023. doi: 10.1371/journal.pcbi.1004023. eCollection 2015 Jan.


Protein Design. What I cannot create, I do not understand.

Lupas AN.

Science. 2014 Dec 19;346(6216):1455-6. doi: 10.1126/science.aaa2721. No abstract available.


Thalidomide mimics uridine binding to an aromatic cage in cereblon.

Hartmann MD, Boichenko I, Coles M, Zanini F, Lupas AN, Hernandez Alvarez B.

J Struct Biol. 2014 Dec;188(3):225-32. doi: 10.1016/j.jsb.2014.10.010. Epub 2014 Nov 4.


Crystallographic snapshot of the Escherichia coli EnvZ histidine kinase in an active conformation.

Ferris HU, Coles M, Lupas AN, Hartmann MD.

J Struct Biol. 2014 Jun;186(3):376-9. doi: 10.1016/j.jsb.2014.03.014. Epub 2014 Mar 26.


Axial helix rotation as a mechanism for signal regulation inferred from the crystallographic analysis of the E. coli serine chemoreceptor.

Ferris HU, Zeth K, Hulko M, Dunin-Horkawicz S, Lupas AN.

J Struct Biol. 2014 Jun;186(3):349-56. doi: 10.1016/j.jsb.2014.03.015. Epub 2014 Mar 27.


A soluble mutant of the transmembrane receptor Af1503 features strong changes in coiled-coil periodicity.

Hartmann MD, Dunin-Horkawicz S, Hulko M, Martin J, Coles M, Lupas AN.

J Struct Biol. 2014 Jun;186(3):357-66. doi: 10.1016/j.jsb.2014.02.008. Epub 2014 Feb 22.


Prokaryotic ancestry of eukaryotic protein networks mediating innate immunity and apoptosis.

Dunin-Horkawicz S, Kopec KO, Lupas AN.

J Mol Biol. 2014 Apr 3;426(7):1568-82. doi: 10.1016/j.jmb.2013.11.030. Epub 2013 Dec 9.


β-Propeller blades as ancestral peptides in protein evolution.

Kopec KO, Lupas AN.

PLoS One. 2013 Oct 15;8(10):e77074. doi: 10.1371/journal.pone.0077074. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/fee01544-ff98-4ed2-9dc9-7aea9c5fe828.


The first prokaryotic trehalose synthase complex identified in the hyperthermophilic crenarchaeon Thermoproteus tenax.

Zaparty M, Hagemann A, Bräsen C, Hensel R, Lupas AN, Brinkmann H, Siebers B.

PLoS One. 2013 Apr 23;8(4):e61354. doi: 10.1371/journal.pone.0061354. Print 2013.


Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria.

Hartmann MD, Grin I, Dunin-Horkawicz S, Deiss S, Linke D, Lupas AN, Hernandez Alvarez B.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20907-12. doi: 10.1073/pnas.1211872110. Epub 2012 Dec 3.


The archaeal proteasome is regulated by a network of AAA ATPases.

Forouzan D, Ammelburg M, Hobel CF, Ströh LJ, Sessler N, Martin J, Lupas AN.

J Biol Chem. 2012 Nov 9;287(46):39254-62. doi: 10.1074/jbc.M112.386458. Epub 2012 Sep 19.

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