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Results: 1 to 20 of 90


A domain dictionary of trimeric autotransporter adhesins.

Bassler J, Hernandez Alvarez B, Hartmann MD, Lupas AN.

Int J Med Microbiol. 2015 Feb;305(2):265-75. doi: 10.1016/j.ijmm.2014.12.010. Epub 2014 Dec 24.


Structure and evolution of N-domains in AAA metalloproteases.

Scharfenberg F, Serek-Heuberger J, Coles M, Hartmann MD, Habeck M, Martin J, Lupas AN, Alva V.

J Mol Biol. 2015 Feb 27;427(4):910-23. doi: 10.1016/j.jmb.2014.12.024. Epub 2015 Jan 8.


The thalidomide-binding domain of cereblon defines the CULT domain family and is a new member of the β-tent fold.

Lupas AN, Zhu H, Korycinski M.

PLoS Comput Biol. 2015 Jan 8;11(1):e1004023. doi: 10.1371/journal.pcbi.1004023. eCollection 2015 Jan.


Protein Design. What I cannot create, I do not understand.

Lupas AN.

Science. 2014 Dec 19;346(6216):1455-6. doi: 10.1126/science.aaa2721. No abstract available.


Thalidomide mimics uridine binding to an aromatic cage in cereblon.

Hartmann MD, Boichenko I, Coles M, Zanini F, Lupas AN, Hernandez Alvarez B.

J Struct Biol. 2014 Dec;188(3):225-32. doi: 10.1016/j.jsb.2014.10.010. Epub 2014 Nov 4.


Crystallographic snapshot of the Escherichia coli EnvZ histidine kinase in an active conformation.

Ferris HU, Coles M, Lupas AN, Hartmann MD.

J Struct Biol. 2014 Jun;186(3):376-9. doi: 10.1016/j.jsb.2014.03.014. Epub 2014 Mar 26.


Axial helix rotation as a mechanism for signal regulation inferred from the crystallographic analysis of the E. coli serine chemoreceptor.

Ferris HU, Zeth K, Hulko M, Dunin-Horkawicz S, Lupas AN.

J Struct Biol. 2014 Jun;186(3):349-56. doi: 10.1016/j.jsb.2014.03.015. Epub 2014 Mar 27.


A soluble mutant of the transmembrane receptor Af1503 features strong changes in coiled-coil periodicity.

Hartmann MD, Dunin-Horkawicz S, Hulko M, Martin J, Coles M, Lupas AN.

J Struct Biol. 2014 Jun;186(3):357-66. doi: 10.1016/j.jsb.2014.02.008. Epub 2014 Feb 22.


Prokaryotic ancestry of eukaryotic protein networks mediating innate immunity and apoptosis.

Dunin-Horkawicz S, Kopec KO, Lupas AN.

J Mol Biol. 2014 Apr 3;426(7):1568-82. doi: 10.1016/j.jmb.2013.11.030. Epub 2013 Dec 9.


β-Propeller blades as ancestral peptides in protein evolution.

Kopec KO, Lupas AN.

PLoS One. 2013 Oct 15;8(10):e77074. doi: 10.1371/journal.pone.0077074. eCollection 2013. Erratum in: PLoS One. 2014;9(1). doi:10.1371/annotation/fee01544-ff98-4ed2-9dc9-7aea9c5fe828.


The first prokaryotic trehalose synthase complex identified in the hyperthermophilic crenarchaeon Thermoproteus tenax.

Zaparty M, Hagemann A, Bräsen C, Hensel R, Lupas AN, Brinkmann H, Siebers B.

PLoS One. 2013 Apr 23;8(4):e61354. doi: 10.1371/journal.pone.0061354. Print 2013.


Complete fiber structures of complex trimeric autotransporter adhesins conserved in enterobacteria.

Hartmann MD, Grin I, Dunin-Horkawicz S, Deiss S, Linke D, Lupas AN, Hernandez Alvarez B.

Proc Natl Acad Sci U S A. 2012 Dec 18;109(51):20907-12. doi: 10.1073/pnas.1211872110. Epub 2012 Dec 3.


The archaeal proteasome is regulated by a network of AAA ATPases.

Forouzan D, Ammelburg M, Hobel CF, Ströh LJ, Sessler N, Martin J, Lupas AN.

J Biol Chem. 2012 Nov 9;287(46):39254-62. doi: 10.1074/jbc.M112.386458. Epub 2012 Sep 19.


The structure of proteins.

Lupas AN, Russell RB.

J Struct Biol. 2012 Sep;179(3):251. doi: 10.1016/j.jsb.2012.05.012. Epub 2012 May 26. No abstract available.


Mechanism of regulation of receptor histidine kinases.

Ferris HU, Dunin-Horkawicz S, Hornig N, Hulko M, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M.

Structure. 2012 Jan 11;20(1):56-66. doi: 10.1016/j.str.2011.11.014.


Evolutionary relationships of microbial aromatic prenyltransferases.

Bonitz T, Alva V, Saleh O, Lupas AN, Heide L.

PLoS One. 2011;6(11):e27336. doi: 10.1371/journal.pone.0027336. Epub 2011 Nov 30.


Bioinformatics of the TULIP domain superfamily.

Kopec KO, Alva V, Lupas AN.

Biochem Soc Trans. 2011 Aug;39(4):1033-8. doi: 10.1042/BST0391033. Review.


Structure and function of tripeptidyl peptidase II, a giant cytosolic protease.

Rockel B, Kopec KO, Lupas AN, Baumeister W.

Biochim Biophys Acta. 2012 Jan;1824(1):237-45. doi: 10.1016/j.bbapap.2011.07.002. Epub 2011 Jul 13. Review.


The structure of E. coli IgG-binding protein D suggests a general model for bending and binding in trimeric autotransporter adhesins.

Leo JC, Lyskowski A, Hattula K, Hartmann MD, Schwarz H, Butcher SJ, Linke D, Lupas AN, Goldman A.

Structure. 2011 Jul 13;19(7):1021-30. doi: 10.1016/j.str.2011.03.021.


The mechanisms of HAMP-mediated signaling in transmembrane receptors.

Ferris HU, Dunin-Horkawicz S, Mondéjar LG, Hulko M, Hantke K, Martin J, Schultz JE, Zeth K, Lupas AN, Coles M.

Structure. 2011 Mar 9;19(3):378-85. doi: 10.1016/j.str.2011.01.006.

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