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Results: 1 to 20 of 308

1.

Blood Protein Markers of Neocortical Amyloid-β Burden: A Candidate Study Using SOMAscan Technology.

Voyle N, Baker D, Burnham SC, Covin A, Zhang Z, Sangurdekar DP, Tan Hehir CA, Bazenet C, Lovestone S, Kiddle S, Dobson RJ.

J Alzheimers Dis. 2015 Apr 16. [Epub ahead of print]

PMID:
25881911
2.

Boosting translational research on Alzheimer's disease in Europe: The Innovative Medicine Initiative AD research platform.

Vaudano E, Vannieuwenhuyse B, Van Der Geyten S, van der Lei J, Visser PJ, Streffer J, Ritchie C, McHale D, Lovestone S, Hofmann-Apitius M, Truyen L, Goldman M.

Alzheimers Dement. 2015 Apr 7. pii: S1552-5260(15)00057-6. doi: 10.1016/j.jalz.2015.02.002. [Epub ahead of print] No abstract available.

PMID:
25754460
3.

Practical cut-offs for visual rating scales of medial temporal, frontal and posterior atrophy in Alzheimer's disease and mild cognitive impairment.

Ferreira D, Cavallin L, Larsson EM, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Simmons A, Wahlund LO, Westman E; AddNeuroMed consortium and the Alzheimer's Disease Neuroimaging Initiative.

J Intern Med. 2015 Mar 9. doi: 10.1111/joim.12358. [Epub ahead of print]

PMID:
25752192
4.

Prevalence and prognosis of Alzheimer's disease at the mild cognitive impairment stage.

Vos SJ, Verhey F, Frölich L, Kornhuber J, Wiltfang J, Maier W, Peters O, Rüther E, Nobili F, Morbelli S, Frisoni GB, Drzezga A, Didic M, van Berckel BN, Simmons A, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Muscio C, Herukka SK, Salmon E, Bastin C, Wallin A, Nordlund A, de Mendonça A, Silva D, Santana I, Lemos R, Engelborghs S, Van der Mussele S; Alzheimer’s Disease Neuroimaging Initiative, Freund-Levi Y, Wallin ÅK, Hampel H, van der Flier W, Scheltens P, Visser PJ.

Brain. 2015 May;138(Pt 5):1327-38. doi: 10.1093/brain/awv029. Epub 2015 Feb 17.

PMID:
25693589
5.

Linking Genetics of Brain Changes to Alzheimer's Disease: Sparse Whole Genome Association Scan of Regional MRI Volumes in the ADNI and AddNeuroMed Cohorts.

Khondoker M, Newhouse S, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Dobson R, Simmons A.

J Alzheimers Dis. 2015 Jan 1;45(3):851-64. doi: 10.3233/JAD-142214.

PMID:
25649652
6.

Common genetic variants influence human subcortical brain structures.

Hibar DP, Stein JL, Renteria ME, Arias-Vasquez A, Desrivières S, Jahanshad N, Toro R, Wittfeld K, Abramovic L, Andersson M, Aribisala BS, Armstrong NJ, Bernard M, Bohlken MM, Boks MP, Bralten J, Brown AA, Chakravarty MM, Chen Q, Ching CR, Cuellar-Partida G, den Braber A, Giddaluru S, Goldman AL, Grimm O, Guadalupe T, Hass J, Woldehawariat G, Holmes AJ, Hoogman M, Janowitz D, Jia T, Kim S, Klein M, Kraemer B, Lee PH, Olde Loohuis LM, Luciano M, Macare C, Mather KA, Mattheisen M, Milaneschi Y, Nho K, Papmeyer M, Ramasamy A, Risacher SL, Roiz-Santiañez R, Rose EJ, Salami A, Sämann PG, Schmaal L, Schork AJ, Shin J, Strike LT, Teumer A, van Donkelaar MM, van Eijk KR, Walters RK, Westlye LT, Whelan CD, Winkler AM, Zwiers MP, Alhusaini S, Athanasiu L, Ehrlich S, Hakobjan MM, Hartberg CB, Haukvik UK, Heister AJ, Hoehn D, Kasperaviciute D, Liewald DC, Lopez LM, Makkinje RR, Matarin M, Naber MA, McKay DR, Needham M, Nugent AC, Pütz B, Royle NA, Shen L, Sprooten E, Trabzuni D, van der Marel SS, van Hulzen KJ, Walton E, Wolf C, Almasy L, Ames D, Arepalli S, Assareh AA, Bastin ME, Brodaty H, Bulayeva KB, Carless MA, Cichon S, Corvin A, Curran JE, Czisch M, de Zubicaray GI, Dillman A, Duggirala R, Dyer TD, Erk S, Fedko IO, Ferrucci L, Foroud TM, Fox PT, Fukunaga M, Gibbs JR, Göring HH, Green RC, Guelfi S, Hansell NK, Hartman CA, Hegenscheid K, Heinz A, Hernandez DG, Heslenfeld DJ, Hoekstra PJ, Holsboer F, Homuth G, Hottenga JJ, Ikeda M, Jack CR Jr, Jenkinson M, Johnson R, Kanai R, Keil M, Kent JW Jr, Kochunov P, Kwok JB, Lawrie SM, Liu X, Longo DL, McMahon KL, Meisenzahl E, Melle I, Mohnke S, Montgomery GW, Mostert JC, Mühleisen TW, Nalls MA, Nichols TE, Nilsson LG, Nöthen MM, Ohi K, Olvera RL, Perez-Iglesias R, Pike GB, Potkin SG, Reinvang I, Reppermund S, Rietschel M, Romanczuk-Seiferth N, Rosen GD, Rujescu D, Schnell K, Schofield PR, Smith C, Steen VM, Sussmann JE, Thalamuthu A, Toga AW, Traynor BJ, Troncoso J, Turner JA, Valdés Hernández MC, van 't Ent D, van der Brug M, van der Wee NJ, van Tol MJ, Veltman DJ, Wassink TH, Westman E, Zielke RH, Zonderman AB, Ashbrook DG, Hager R, Lu L, McMahon FJ, Morris DW, Williams RW, Brunner HG, Buckner RL, Buitelaar JK, Cahn W, Calhoun VD, Cavalleri GL, Crespo-Facorro B, Dale AM, Davies GE, Delanty N, Depondt C, Djurovic S, Drevets WC, Espeseth T, Gollub RL, Ho BC, Hoffmann W, Hosten N, Kahn RS, Le Hellard S, Meyer-Lindenberg A, Müller-Myhsok B, Nauck M, Nyberg L, Pandolfo M, Penninx BW, Roffman JL, Sisodiya SM, Smoller JW, van Bokhoven H, van Haren NE, Völzke H, Walter H, Weiner MW, Wen W, White T, Agartz I, Andreassen OA, Blangero J, Boomsma DI, Brouwer RM, Cannon DM, Cookson MR, de Geus EJ, Deary IJ, Donohoe G, Fernández G, Fisher SE, Francks C, Glahn DC, Grabe HJ, Gruber O, Hardy J, Hashimoto R, Hulshoff Pol HE, Jönsson EG, Kloszewska I, Lovestone S, Mattay VS, Mecocci P, McDonald C, McIntosh AM, Ophoff RA, Paus T, Pausova Z, Ryten M, Sachdev PS, Saykin AJ, Simmons A, Singleton A, Soininen H, Wardlaw JM, Weale ME, Weinberger DR, Adams HH, Launer LJ, Seiler S, Schmidt R, Chauhan G, Satizabal CL, Becker JT, Yanek L, van der Lee SJ, Ebling M, Fischl B, Longstreth WT Jr, Greve D, Schmidt H, Nyquist P, Vinke LN, van Duijn CM, Xue L, Mazoyer B, Bis JC, Gudnason V, Seshadri S, Ikram MA; Alzheimer’s Disease Neuroimaging Initiative; CHARGE Consortium; EPIGEN; IMAGEN; SYS, Martin NG, Wright MJ, Schumann G, Franke B, Thompson PM, Medland SE.

Nature. 2015 Apr 9;520(7546):224-9. doi: 10.1038/nature14101. Epub 2015 Jan 21.

7.

Plasma lipidomics analysis finds long chain cholesteryl esters to be associated with Alzheimer's disease.

Proitsi P, Kim M, Whiley L, Pritchard M, Leung R, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Sham P, Lovestone S, Powell JF, Dobson RJ, Legido-Quigley C.

Transl Psychiatry. 2015 Jan 13;5:e494. doi: 10.1038/tp.2014.127.

8.

Protective variant for hippocampal atrophy identified by whole exome sequencing.

Nho K, Kim S, Risacher SL, Shen L, Corneveaux JJ, Swaminathan S, Lin H, Ramanan VK, Liu Y, Foroud TM, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR Jr, Weiner MW, Baldwin CT, Lunetta KL, Farrer LA; MIRAGE (Multi-Institutional Research on Alzheimer Genetic Epidemiology) Study, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H; AddNeuroMed Consortium, McDonald BC, Farlow MR, Ghetti B; Indiana Memory and Aging Study, Huentelman MJ, Saykin AJ; Alzheimer's Disease Neuroimaging Initiative.

Ann Neurol. 2015 Mar;77(3):547-52. doi: 10.1002/ana.24349. Epub 2015 Feb 14.

PMID:
25559091
9.

A phase II trial of tideglusib in Alzheimer's disease.

Lovestone S, Boada M, Dubois B, Hüll M, Rinne JO, Huppertz HJ, Calero M, Andrés MV, Gómez-Carrillo B, León T, del Ser T; ARGO investigators.

J Alzheimers Dis. 2015;45(1):75-88. doi: 10.3233/JAD-141959.

PMID:
25537011
10.

The Notch intracellular domain represses CRE-dependent transcription.

Hallaq R, Volpicelli F, Cuchillo-Ibanez I, Hooper C, Mizuno K, Uwanogho D, Causevic M, Asuni A, To A, Soriano S, Giese KP, Lovestone S, Killick R.

Cell Signal. 2015 Mar;27(3):621-9. doi: 10.1016/j.cellsig.2014.11.034. Epub 2014 Dec 3.

11.

Blood biomarkers for Alzheimer's disease.

Lovestone S.

Genome Med. 2014 Aug 31;6(8):65. doi: 10.1186/s13073-014-0065-7. eCollection 2014.

12.

Developing a new model for patient recruitment in mental health services: a cohort study using Electronic Health Records.

Callard F, Broadbent M, Denis M, Hotopf M, Soncul M, Wykes T, Lovestone S, Stewart R.

BMJ Open. 2014 Dec 2;4(12):e005654. doi: 10.1136/bmjopen-2014-005654.

13.

FASTKD2 is associated with memory and hippocampal structure in older adults.

Ramanan VK, Nho K, Shen L, Risacher SL, Kim S, McDonald BC, Farlow MR, Foroud TM, Gao S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Aisen PS, Petersen RC, Jack CR Jr, Shaw LM, Trojanowski JQ, Weiner MW, Green RC, Toga AW, De Jager PL, Yu L, Bennett DA, Saykin AJ.

Mol Psychiatry. 2014 Nov 11. doi: 10.1038/mp.2014.142. [Epub ahead of print]

PMID:
25385369
14.

Random Forest ensembles for detection and prediction of Alzheimer's disease with a good between-cohort robustness.

Lebedev AV, Westman E, Van Westen GJ, Kramberger MG, Lundervold A, Aarsland D, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Simmons A; Alzheimer's Disease Neuroimaging Initiative and the AddNeuroMed consortium.

Neuroimage Clin. 2014 Aug 28;6:115-25. doi: 10.1016/j.nicl.2014.08.023. eCollection 2014.

15.

Automated Hippocampal Subfield Measures as Predictors of Conversion from Mild Cognitive Impairment to Alzheimer's Disease in Two Independent Cohorts.

Khan W, Westman E, Jones N, Wahlund LO, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Lovestone S, Muehlboeck JS, Simmons A; for the AddNeuroMed consortium and for the Alzheimer’s Disease Neuroimaging Initiative.

Brain Topogr. 2014 Nov 5. [Epub ahead of print]

PMID:
25370484
16.

Guidelines for the standardization of preanalytic variables for blood-based biomarker studies in Alzheimer's disease research.

O'Bryant SE, Gupta V, Henriksen K, Edwards M, Jeromin A, Lista S, Bazenet C, Soares H, Lovestone S, Hampel H, Montine T, Blennow K, Foroud T, Carrillo M, Graff-Radford N, Laske C, Breteler M, Shaw L, Trojanowski JQ, Schupf N, Rissman RA, Fagan AM, Oberoi P, Umek R, Weiner MW, Grammas P, Posner H, Martins R; STAR-B and BBBIG working groups.

Alzheimers Dement. 2015 May;11(5):549-560. doi: 10.1016/j.jalz.2014.08.099. Epub 2014 Oct 1. Review.

17.

Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a mendelian randomization analysis.

Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B; Alzheimer's Disease Neuroimaging Initiative, Williams J; GERAD1 Consortium, Stewart R, Sham P, Lovestone S, Powell JF.

PLoS Med. 2014 Sep 16;11(9):e1001713. doi: 10.1371/journal.pmed.1001713. eCollection 2014 Sep.

18.

Generalizability of the disease state index prediction model for identifying patients progressing from mild cognitive impairment to Alzheimer's disease.

Hall A, Muñoz-Ruiz M, Mattila J, Koikkalainen J, Tsolaki M, Mecocci P, Kloszewska I, Vellas B, Lovestone S, Visser PJ, Lötjonen J, Soininen H; Alzheimer Disease Neuroimaging Initiative; AddNeuroMed consortium; DESCRIPA and Kuopio L-MCI.

J Alzheimers Dis. 2015;44(1):79-92. doi: 10.3233/JAD-140942.

PMID:
25201784
19.

Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.

Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, Soininen H, Mecocci P, Vellas B, Passmore PA, Sims R, Williams J, Brayne C; Alzheimer's Disease Neuroimaging Initiative; GERAD1 Consortium, Stewart R, Sham P, Lovestone S, Powell JF.

Neurobiol Aging. 2014 Dec;35(12):2883.e3-2883.e10. doi: 10.1016/j.neurobiolaging.2014.07.023. Epub 2014 Jul 24.

PMID:
25150574
20.

Predicting progression of Alzheimer's disease using ordinal regression.

Doyle OM, Westman E, Marquand AF, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Lovestone S, Williams SC, Simmons A.

PLoS One. 2014 Aug 20;9(8):e105542. doi: 10.1371/journal.pone.0105542. eCollection 2014.

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