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Results: 1 to 20 of 285

1.

Plasma proteins predict conversion to dementia from prodromal disease.

Hye A, Riddoch-Contreras J, Baird AL, Ashton NJ, Bazenet C, Leung R, Westman E, Simmons A, Dobson R, Sattlecker M, Lupton M, Lunnon K, Keohane A, Ward M, Pike I, Zucht HD, Pepin D, Zheng W, Tunnicliffe A, Richardson J, Gauthier S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S.

Alzheimers Dement. 2014 Jul 3. pii: S1552-5260(14)02454-6. doi: 10.1016/j.jalz.2014.05.1749. [Epub ahead of print]

PMID:
25012867
[PubMed - as supplied by publisher]
2.

Gene-wide analysis detects two new susceptibility genes for Alzheimer's disease.

Escott-Price V, Bellenguez C, Wang LS, Choi SH, Harold D, Jones L, Holmans P, Gerrish A, Vedernikov A, Richards A, DeStefano AL, Lambert JC, Ibrahim-Verbaas CA, Naj AC, Sims R, Jun G, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thornton-Wells TA, Denning N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Schmidt H, Kunkle B, Dunstan ML, Vronskaya M; United Kingdom Brain Expression Consortium, Johnson AD, Ruiz A, Bihoreau MT, Reitz C, Pasquier F, Hollingworth P, Hanon O, Fitzpatrick AL, Buxbaum JD, Campion D, Crane PK, Baldwin C, Becker T, Gudnason V, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Hernández I, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MJ, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuinness B, Larson EB, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, George-Hyslop PS, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Garcia FS, Fox NC, Hardy J, Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Scarpini E, Bonuccelli U, Mancuso M, Siciliano G, Moebus S, Mecocci P, Zompo MD, Maier W, Hampel H, Pilotto A, Frank-García A, Panza F, Solfrizzi V, Caffarra P, Nacmias B, Perry W, Mayhaus M, Lannfelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltunen M, Martin ER, Schmidt R, Rujescu D, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Haines JL, Lathrop M, Pericak-Vance MA, Launer LJ, Van Broeckhoven C, Farrer LA, van Duijn CM, Ramirez A, Seshadri S, Schellenberg GD, Amouyel P, Williams J.

PLoS One. 2014 Jun 12;9(6):e94661. doi: 10.1371/journal.pone.0094661. eCollection 2014.

PMID:
24922517
[PubMed - in process]
Free PMC Article
3.

Alzheimer's disease biomarker discovery using SOMAscan multiplexed protein technology.

Sattlecker M, Kiddle SJ, Newhouse S, Proitsi P, Nelson S, Williams S, Johnston C, Killick R, Simmons A, Westman E, Hodges A, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S; the AddNeuroMed Consortium, Dobson RJ.

Alzheimers Dement. 2014 Apr 24. pii: S1552-5260(14)00031-4. doi: 10.1016/j.jalz.2013.09.016. [Epub ahead of print]

PMID:
24768341
[PubMed - as supplied by publisher]
Free Article
4.

Advanced glycation end products, dementia, and diabetes.

Lovestone S, Smith U.

Proc Natl Acad Sci U S A. 2014 Apr 1;111(13):4743-4. doi: 10.1073/pnas.1402277111. Epub 2014 Mar 25. No abstract available.

PMID:
24707042
[PubMed - indexed for MEDLINE]
5.

Cross-region reduction in 5-hydroxymethylcytosine in Alzheimer's disease brain.

Condliffe D, Wong A, Troakes C, Proitsi P, Patel Y, Chouliaras L, Fernandes C, Cooper J, Lovestone S, Schalkwyk L, Mill J, Lunnon K.

Neurobiol Aging. 2014 Aug;35(8):1850-4. doi: 10.1016/j.neurobiolaging.2014.02.002. Epub 2014 Feb 6.

PMID:
24679604
[PubMed - in process]
6.

CERAD Neuropsychological Total Scores Reflect Cortical Thinning in Prodromal Alzheimer's Disease.

Paajanen T, Hänninen T, Aitken A, Hallikainen M, Westman E, Wahlund LO, Sobow T, Mecocci P, Tsolaki M, Vellas B, Muehlboeck S, Spenger C, Lovestone S, Simmons A, Soininen H; AddNeuroMed Consortium.

Dement Geriatr Cogn Dis Extra. 2013 Nov 30;3(1):446-58. doi: 10.1159/000356725. eCollection 2013 Jan.

PMID:
24516412
[PubMed]
Free PMC Article
7.

Dynamin protein in stroke and vascular dementia.

Mulugeta E, Vallortigara J, Francis PT, Hye A, Kalaria RN, Perry EK, Lovestone S, Ballard CG.

Neurosci Lett. 2014 Mar 20;563:118-22. doi: 10.1016/j.neulet.2014.01.045. Epub 2014 Jan 31.

PMID:
24486840
[PubMed - in process]
8.

Developing novel blood-based biomarkers for Alzheimer's disease.

Snyder HM, Carrillo MC, Grodstein F, Henriksen K, Jeromin A, Lovestone S, Mielke MM, O'Bryant S, Sarasa M, Sjøgren M, Soares H, Teeling J, Trushina E, Ward M, West T, Bain LJ, Shineman DW, Weiner M, Fillit HM.

Alzheimers Dement. 2014 Jan;10(1):109-14. doi: 10.1016/j.jalz.2013.10.007.

PMID:
24365657
[PubMed - in process]
9.

No differences in hippocampal volume between carriers and non-carriers of the ApoE ε4 and ε2 alleles in young healthy adolescents.

Khan W, Giampietro V, Ginestet C, Dell'Acqua F, Bouls D, Newhouse S, Dobson R, Banaschewski T, Barker GJ, Bokde AL, Büchel C, Conrod P, Flor H, Frouin V, Garavan H, Gowland P, Heinz A, Ittermann B, Lemaître H, Nees F, Paus T, Pausova Z, Rietschel M, Smolka MN, Ströhle A, Gallinat J, Westman E, Schumann G, Lovestone S, Simmons A; IMAGEN consortium.

J Alzheimers Dis. 2014;40(1):37-43. doi: 10.3233/JAD-131841.

PMID:
24326516
[PubMed - in process]
10.

CERAD neuropsychological compound scores are accurate in detecting prodromal alzheimer's disease: a prospective AddNeuroMed study.

Paajanen T, Hänninen T, Tunnard C, Hallikainen M, Mecocci P, Sobow T, Tsolaki M, Vellas B, Lovestone S, Soininen H.

J Alzheimers Dis. 2014;39(3):679-90. doi: 10.3233/JAD-122110.

PMID:
24246420
[PubMed - in process]
11.

Meta-analysis of 74,046 individuals identifies 11 new susceptibility loci for Alzheimer's disease.

Lambert JC, Ibrahim-Verbaas CA, Harold D, Naj AC, Sims R, Bellenguez C, DeStafano AL, Bis JC, Beecham GW, Grenier-Boley B, Russo G, Thorton-Wells TA, Jones N, Smith AV, Chouraki V, Thomas C, Ikram MA, Zelenika D, Vardarajan BN, Kamatani Y, Lin CF, Gerrish A, Schmidt H, Kunkle B, Dunstan ML, Ruiz A, Bihoreau MT, Choi SH, Reitz C, Pasquier F, Cruchaga C, Craig D, Amin N, Berr C, Lopez OL, De Jager PL, Deramecourt V, Johnston JA, Evans D, Lovestone S, Letenneur L, Morón FJ, Rubinsztein DC, Eiriksdottir G, Sleegers K, Goate AM, Fiévet N, Huentelman MW, Gill M, Brown K, Kamboh MI, Keller L, Barberger-Gateau P, McGuiness B, Larson EB, Green R, Myers AJ, Dufouil C, Todd S, Wallon D, Love S, Rogaeva E, Gallacher J, St George-Hyslop P, Clarimon J, Lleo A, Bayer A, Tsuang DW, Yu L, Tsolaki M, Bossù P, Spalletta G, Proitsi P, Collinge J, Sorbi S, Sanchez-Garcia F, Fox NC, Hardy J, Deniz Naranjo MC, Bosco P, Clarke R, Brayne C, Galimberti D, Mancuso M, Matthews F; European Alzheimer's Disease Initiative (EADI); Genetic and Environmental Risk in Alzheimer's Disease; Alzheimer's Disease Genetic Consortium; Cohorts for Heart and Aging Research in Genomic Epidemiology, Moebus S, Mecocci P, Del Zompo M, Maier W, Hampel H, Pilotto A, Bullido M, Panza F, Caffarra P, Nacmias B, Gilbert JR, Mayhaus M, Lannefelt L, Hakonarson H, Pichler S, Carrasquillo MM, Ingelsson M, Beekly D, Alvarez V, Zou F, Valladares O, Younkin SG, Coto E, Hamilton-Nelson KL, Gu W, Razquin C, Pastor P, Mateo I, Owen MJ, Faber KM, Jonsson PV, Combarros O, O'Donovan MC, Cantwell LB, Soininen H, Blacker D, Mead S, Mosley TH Jr, Bennett DA, Harris TB, Fratiglioni L, Holmes C, de Bruijn RF, Passmore P, Montine TJ, Bettens K, Rotter JI, Brice A, Morgan K, Foroud TM, Kukull WA, Hannequin D, Powell JF, Nalls MA, Ritchie K, Lunetta KL, Kauwe JS, Boerwinkle E, Riemenschneider M, Boada M, Hiltuenen M, Martin ER, Schmidt R, Rujescu D, Wang LS, Dartigues JF, Mayeux R, Tzourio C, Hofman A, Nöthen MM, Graff C, Psaty BM, Jones L, Haines JL, Holmans PA, Lathrop M, Pericak-Vance MA, Launer LJ, Farrer LA, van Duijn CM, Van Broeckhoven C, Moskvina V, Seshadri S, Williams J, Schellenberg GD, Amouyel P.

Nat Genet. 2013 Dec;45(12):1452-8. doi: 10.1038/ng.2802. Epub 2013 Oct 27.

PMID:
24162737
[PubMed - indexed for MEDLINE]
Free PMC Article
12.

Candidate blood proteome markers of Alzheimer's disease onset and progression: a systematic review and replication study.

Kiddle SJ, Sattlecker M, Proitsi P, Simmons A, Westman E, Bazenet C, Nelson SK, Williams S, Hodges A, Johnston C, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Newhouse S, Lovestone S, Dobson RJ.

J Alzheimers Dis. 2014;38(3):515-31. doi: 10.3233/JAD-130380. Review.

PMID:
24121966
[PubMed - indexed for MEDLINE]
13.

Influence of age, disease onset and ApoE4 on visual medial temporal lobe atrophy cut-offs.

Pereira JB, Cavallin L, Spulber G, Aguilar C, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Aarsland D, Lovestone S, Simmons A, Wahlund LO, Westman E; AddNeuroMed consortium and for the Alzheimer's Disease Neuroimaging Initiative.

J Intern Med. 2014 Mar;275(3):317-30. doi: 10.1111/joim.12148. Epub 2013 Oct 30.

PMID:
24118559
[PubMed - indexed for MEDLINE]
14.

Alzheimer's disease susceptibility variants in the MS4A6A gene are associated with altered levels of MS4A6A expression in blood.

Proitsi P, Lee SH, Lunnon K, Keohane A, Powell J, Troakes C, Al-Sarraj S, Furney S, Soininen H, Kłoszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Hodges A; AddNeuroMed Consortium.

Neurobiol Aging. 2014 Feb;35(2):279-90. doi: 10.1016/j.neurobiolaging.2013.08.002. Epub 2013 Sep 21.

PMID:
24064185
[PubMed - in process]
15.

Evidence of altered phosphatidylcholine metabolism in Alzheimer's disease.

Whiley L, Sen A, Heaton J, Proitsi P, García-Gómez D, Leung R, Smith N, Thambisetty M, Kloszewska I, Mecocci P, Soininen H, Tsolaki M, Vellas B, Lovestone S, Legido-Quigley C; AddNeuroMed Consortium.

Neurobiol Aging. 2014 Feb;35(2):271-8. doi: 10.1016/j.neurobiolaging.2013.08.001. Epub 2013 Sep 13.

PMID:
24041970
[PubMed - in process]
16.

Correction: Harnessing Clinical Psychiatric Data with an Electronic Assessment Tool (OPCRIT+): The Utility of Symptom Dimensions.

Brittain PJ, Lobo SE, Rucker J, Amarasinghe M, Anilkumar AP, Baggaley M, Banerjee P, Bearn J, Broadbent M, Butler M, Campbell CD, Cleare AJ, Dratcu L, Frangou S, Gaughran F, Goldin M, Henke A, Kern N, Krayem A, Mufti F, McIvor R, Needham-Bennett H, Newman S, Olajide D, O'Flynn D, Rao R, Rehman IU, Seneviratne G, Stahl D, Suleman S, Treasure J, Tully J, Veale D, Stewart R, McGuffin P, Lovestone S, Hotopf M, Schumann G.

PLoS One. 2013 Sep 10;8(9). doi: 10.1371/annotation/d026ac78-2460-40ac-a045-98e95a7b1783. eCollection 2013.

PMID:
24039681
[PubMed - as supplied by publisher]
Free PMC Article
17.

Dementia in Down's syndrome: an MRI comparison with Alzheimer's disease in the general population.

Mullins D, Daly E, Simmons A, Beacher F, Foy CM, Lovestone S, Hallahan B, Murphy KC, Murphy DG.

J Neurodev Disord. 2013 Aug 20;5(1):19. doi: 10.1186/1866-1955-5-19.

PMID:
23962297
[PubMed]
Free PMC Article
18.

The future of blood-based biomarkers for Alzheimer's disease.

Henriksen K, O'Bryant SE, Hampel H, Trojanowski JQ, Montine TJ, Jeromin A, Blennow K, Lönneborg A, Wyss-Coray T, Soares H, Bazenet C, Sjögren M, Hu W, Lovestone S, Karsdal MA, Weiner MW; Blood-Based Biomarker Interest Group.

Alzheimers Dement. 2014 Jan;10(1):115-31. doi: 10.1016/j.jalz.2013.01.013. Epub 2013 Jul 11.

PMID:
23850333
[PubMed - in process]
19.

The importance of tau phosphorylation for neurodegenerative diseases.

Noble W, Hanger DP, Miller CC, Lovestone S.

Front Neurol. 2013 Jul 1;4:83. doi: 10.3389/fneur.2013.00083. eCollection 2013.

PMID:
23847585
[PubMed]
Free PMC Article
20.

Identification of functional variants from whole-exome sequencing, combined with neuroimaging genetics.

Nho K, Corneveaux JJ, Kim S, Lin H, Risacher SL, Shen L, Swaminathan S, Ramanan VK, Liu Y, Foroud T, Inlow MH, Siniard AL, Reiman RA, Aisen PS, Petersen RC, Green RC, Jack CR, Weiner MW, Baldwin CT, Lunetta K, Farrer LA; Multi-Institutional Research on Alzheimer Genetic Epidemiology (MIRAGE) Study, Furney SJ, Lovestone S, Simmons A, Mecocci P, Vellas B, Tsolaki M, Kloszewska I, Soininen H; AddNeuroMed Consortium, McDonald BC, Farlow MR, Ghetti B; Indiana Memory and Aging Study, Huentelman MJ, Saykin AJ; Alzheimer's Disease Neuroimaging Initiative (ADNI).

Mol Psychiatry. 2013 Jul;18(7):739. doi: 10.1038/mp.2013.81. No abstract available.

PMID:
23787478
[PubMed - indexed for MEDLINE]
Free PMC Article

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