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Results: 1 to 20 of 34

1.

Adaptive evolution as a predictor of species-specific innate immune response.

Webb AE, Gerek ZN, Morgan CC, Walsh TA, Loscher CE, Edwards SV, O'Connell MJ.

Mol Biol Evol. 2015 Mar 10. pii: msv051. [Epub ahead of print]

2.

A role for syntaxin 3 in the secretion of IL-6 from dendritic cells following activation of toll-like receptors.

Collins LE, DeCourcey J, Rochfort KD, Kristek M, Loscher CE.

Front Immunol. 2015 Jan 26;5:691. doi: 10.3389/fimmu.2014.00691. eCollection 2014.

3.

Soluble factors from colonic epithelial cells contribute to gut homeostasis by modulating macrophage phenotype.

Kristek M, Collins LE, DeCourcey J, McEvoy FA, Loscher CE.

Innate Immun. 2014 Oct 7. pii: 1753425914538294. [Epub ahead of print]

PMID:
25298104
4.

Adult vascular smooth muscle cells in culture express neural stem cell markers typical of resident multipotent vascular stem cells.

Kennedy E, Mooney CJ, Hakimjavadi R, Fitzpatrick E, Guha S, Collins LE, Loscher CE, Morrow D, Redmond EM, Cahill PA.

Cell Tissue Res. 2014 Oct;358(1):203-16. doi: 10.1007/s00441-014-1937-2. Epub 2014 Jul 4.

PMID:
24992927
5.

Intracellular pH-sensing using core/shell silica nanoparticles.

Korzeniowska B, Woolley R, DeCourcey J, Wencel D, Loscher CE, McDonagh C.

J Biomed Nanotechnol. 2014 Jul;10(7):1336-45.

PMID:
24804554
6.

Conjugated linoleic acid suppresses dendritic cell activation and subsequent Th17 responses.

Draper E, DeCourcey J, Higgins SC, Canavan M, McEvoy F, Lynch M, Keogh B, Reynolds C, Roche HM, Mills KH, Loscher CE.

J Nutr Biochem. 2014 Jul;25(7):741-9. doi: 10.1016/j.jnutbio.2014.03.004. Epub 2014 Mar 27.

PMID:
24794016
7.

Embryonic rat vascular smooth muscle cells revisited - a model for neonatal, neointimal SMC or differentiated vascular stem cells?

Kennedy E, Hakimjavadi R, Greene C, Mooney CJ, Fitzpatrick E, Collins LE, Loscher CE, Guha S, Morrow D, Redmond EM, Cahill PA.

Vasc Cell. 2014 Mar 15;6(1):6. doi: 10.1186/2045-824X-6-6.

8.

Surface layer proteins isolated from Clostridium difficile induce clearance responses in macrophages.

Collins LE, Lynch M, Marszalowska I, Kristek M, Rochfort K, O'Connell M, Windle H, Kelleher D, Loscher CE.

Microbes Infect. 2014 May;16(5):391-400. doi: 10.1016/j.micinf.2014.02.001. Epub 2014 Feb 19.

PMID:
24560642
9.

Syntaxin-4 is essential for IgE secretion by plasma cells.

Rahman A, Decourcey J, Larbi NB, Loughran ST, Walls D, Loscher CE.

Biochem Biophys Res Commun. 2013 Oct 11;440(1):163-7. doi: 10.1016/j.bbrc.2013.09.058. Epub 2013 Sep 18.

PMID:
24055037
10.

Activation of liver X receptor suppresses the production of the IL-12 family of cytokines by blocking nuclear translocation of NF-κBp50.

Canavan M, McCarthy C, Larbi NB, Dowling JK, Collins L, O'Sullivan F, Hurley G, Murphy C, Quinlan A, Moloney G, Darby T, MacSharry J, Kagechika H, Moynagh P, Melgar S, Loscher CE.

Innate Immun. 2014 Oct;20(7):675-87. doi: 10.1177/1753425913501915. Epub 2013 Sep 17.

PMID:
24045337
11.

Conjugated linoleic acid suppresses IRF3 activation via modulation of CD14.

Dowling JK, McCoy CE, Doyle SL, BenLarbi N, Canavan M, O'Neill LA, Loscher CE.

J Nutr Biochem. 2013 May;24(5):920-8. doi: 10.1016/j.jnutbio.2012.06.010. Epub 2012 Aug 15.

PMID:
22901688
12.

Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions.

Morgan CC, Shakya K, Webb A, Walsh TA, Lynch M, Loscher CE, Ruskin HJ, O'Connell MJ.

BMC Evol Biol. 2012 Jul 12;12:114. doi: 10.1186/1471-2148-12-114.

13.

Aflatoxins B(1), B(2) and G(1) modulate cytokine secretion and cell surface marker expression in J774A.1 murine macrophages.

Bruneau JC, Stack E, O'Kennedy R, Loscher CE.

Toxicol In Vitro. 2012 Aug;26(5):686-93. doi: 10.1016/j.tiv.2012.03.003. Epub 2012 Mar 16.

PMID:
22445859
14.

A role for TLR4 in Clostridium difficile infection and the recognition of surface layer proteins.

Ryan A, Lynch M, Smith SM, Amu S, Nel HJ, McCoy CE, Dowling JK, Draper E, O'Reilly V, McCarthy C, O'Brien J, Ní Eidhin D, O'Connell MJ, Keogh B, Morton CO, Rogers TR, Fallon PG, O'Neill LA, Kelleher D, Loscher CE.

PLoS Pathog. 2011 Jun;7(6):e1002076. doi: 10.1371/journal.ppat.1002076. Epub 2011 Jun 30.

15.

Omega-3 fatty acids attenuate dendritic cell function via NF-κB independent of PPARγ.

Draper E, Reynolds CM, Canavan M, Mills KH, Loscher CE, Roche HM.

J Nutr Biochem. 2011 Aug;22(8):784-90. doi: 10.1016/j.jnutbio.2010.06.009. Epub 2010 Nov 26.

PMID:
21111596
16.

Synthesis and biological evaluation of pyridine-containing lipoxin A4 analogues.

Duffy CD, Maderna P, McCarthy C, Loscher CE, Godson C, Guiry PJ.

ChemMedChem. 2010 Apr 6;5(4):517-22. doi: 10.1002/cmdc.200900533. No abstract available.

PMID:
20127785
17.

A conjugated linoleic acid-enriched beef diet attenuates lipopolysaccharide-induced inflammation in mice in part through PPARgamma-mediated suppression of toll-like receptor 4.

Reynolds CM, Draper E, Keogh B, Rahman A, Moloney AP, Mills KH, Loscher CE, Roche HM.

J Nutr. 2009 Dec;139(12):2351-7. doi: 10.3945/jn.109.113035. Epub 2009 Oct 21.

18.

Attenuation of inflammation and cellular stress-related pathways maintains insulin sensitivity in obese type I interleukin-1 receptor knockout mice on a high-fat diet.

de Roos B, Rungapamestry V, Ross K, Rucklidge G, Reid M, Duncan G, Horgan G, Toomey S, Browne J, Loscher CE, Mills KH, Roche HM.

Proteomics. 2009 Jun;9(12):3244-56. doi: 10.1002/pmic.200800761.

PMID:
19562798
19.

Anti-inflammatory effects of EPA and DHA are dependent upon time and dose-response elements associated with LPS stimulation in THP-1-derived macrophages.

Mullen A, Loscher CE, Roche HM.

J Nutr Biochem. 2010 May;21(5):444-50. doi: 10.1016/j.jnutbio.2009.02.008. Epub 2009 May 8.

PMID:
19427777
20.

The Fasciola hepatica tegumental antigen suppresses dendritic cell maturation and function.

Hamilton CM, Dowling DJ, Loscher CE, Morphew RM, Brophy PM, O'Neill SM.

Infect Immun. 2009 Jun;77(6):2488-98. doi: 10.1128/IAI.00919-08. Epub 2009 Mar 30.

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